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Works (130)
Updated: April 5th, 2024 02:22
2023 journal article
Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer?s disease mouse models
JOURNAL OF CELL SCIENCE, 136(6).
author keywords: Alzheimer?s disease; Cell death; Inflammation; TAK1
MeSH headings : Animals; Mice; Alzheimer Disease / genetics; Calcium; Cytokines / metabolism; Neuroinflammatory Diseases; Signal Transduction / physiology
TL;DR:
It is reported that compound stimulation with the neurotoxic factors TNF and glutamate aberrantly activates neuronal TAK1 (also known as MAP3K7), which promotes the pathogenesis of AD in mouse models and provides a molecular mechanism linking cytokines, Ca2+ signaling and neuronal necroptosis in AD.
(via Semantic Scholar)
doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 30, 2023
2023 journal article
Erosive and ulcerative stomatitis in dogs and cats: which immune-mediated diseases to consider?
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 261, S48–S57.
TL;DR:
Some immune-mediated diseases such as severe adverse drug reactions, lupus diseases, canine uveodermatological syndrome, and vasculitis, may or may not involve the oral cavity, and often nonoral clinical manifestations are more diagnostic.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: September 11, 2023
2023 article
Histopathological characterisation of trunk-dominant canine pemphigus foliaceus, and comparison with classic facial and insecticide-triggered forms
Gedon, N. K. Y., Bizikova, P., Olivry, T., Mendoza-Kuznetsova, E., Oberkirchner, U., Robertson, J. B., & Linder, K. E. (2023, June 14). VETERINARY DERMATOLOGY, Vol. 6.
author keywords: acantholysis; autoimmune diseases; dog diseases; pathological findings; pemphigus; skin diseases
TL;DR:
Trunk-dominant PF and other canine PF variants are histologically similar, which indicates shared pathomechanisms, and results indicate that diagnostic biopsies cannot differentiate between these PF variants in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 3, 2023
2023 journal article
Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst
JOURNAL OF IMMUNOTOXICOLOGY, 20(1).
author keywords: Innate immunity; neutrophils; per- and polyfluoroalkyl substances (PFAS); reactive oxygen species; zebrafish
MeSH headings : Animals; Humans; Zebrafish; Neutrophils; Reactive Oxygen Species; Respiratory Burst; Fluorocarbons / toxicity; Alkanesulfonic Acids / toxicity; Environmental Pollutants
TL;DR:
This report is the first to demonstrate that these PFASs suppress neutrophil function and support the utility of employing zebrafish larvae and a human cell line as screening tools to identify chemicals that may suppress human immune function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 15, 2023
2023 article
Retrospective analysis of histologic lesions in captive arachnids
Gaudette, C., LaDouceur, E. E. B., Troan, B. V., Whitehurst, N., Dombrowski, D. S., Lewbart, G. A., … Schreeg, M. E. (2023, April 10). VETERINARY PATHOLOGY, Vol. 4.
author keywords: Araneae; arthropod; Heterometrus; histopathology; inflammation; invertebrate; scorpion; Scorpiones; tarantula
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 1, 2023
2023 review
Spontaneous autoimmune subepidermal blistering diseases in animals: a comprehensive review
[Review of ]. BMC VETERINARY RESEARCH, 19(1).
author keywords: Autoimmune; Skin; Pemphigoid; Dog; Cat; Blister
MeSH headings : Humans; Animals; Dogs; Skin; Pemphigus / veterinary; Epidermis; Autoantibodies; Breeding; Dog Diseases / diagnosis
TL;DR:
Canine AISBDs are the best characterised, particularly the more common variants such as mucous membrane pemphigoid (48%), epidermolysis bullosa acquisita (EBA) (26%), and bullous pem PHD (10%), and shorter descriptions of variants in other species are provided.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 27, 2023
2022 article
Ameloblastic carcinoma in horses: case report and literature review
Schreeg, M. E., Radkin, M., Haugland, J., Murphy, B. G., Rushton, S., & Linder, K. E. (2022, January 17). JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION.
author keywords: ameloblast; ameloblastic carcinoma; odontogenic neoplasm; odontogenesis; oral tumor; horses
MeSH headings : Ameloblastoma / diagnosis; Ameloblastoma / pathology; Ameloblastoma / veterinary; Animals; Carcinoma / veterinary; Female; Horse Diseases / diagnostic imaging; Horse Diseases / pathology; Horses; Keratins; Mandibular Neoplasms / diagnosis; Mandibular Neoplasms / pathology; Mandibular Neoplasms / veterinary; Odontogenic Tumors / diagnostic imaging; Odontogenic Tumors / veterinary; Vimentin
TL;DR:
Ameloblastic carcinoma should be considered as a differential diagnosis for rapidly growing, locally invasive masses arising from the dentate jaw of horses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: February 7, 2022
2022 article
Cutaneous epitheliotropic lymphosarcoma in a captive white catfish (Ameiurus catus Linnaeus)
Heniff, A. C., Chen, L. R., Christiansen, E. F., Harms, C. A., Law, J. M., Legner, C., & Linder, K. E. (2022, April 27). JOURNAL OF FISH DISEASES, Vol. 4.
author keywords: Ameiurus catus; cutaneous epitheliotropic lymphosarcoma; neoplasia; white catfish
MeSH headings : Animals; Epidermis / pathology; Fish Diseases; Ictaluridae; Lymphoma, Non-Hodgkin; Mammals; Skin Neoplasms / pathology; Skin Neoplasms / veterinary
TL;DR:
This is the first reported case of cutaneous epitheliotropic lymphosarcoma in an ictalurid and one of the few published cases of this condition in any fish species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 28, 2022
2022 article
Cutaneous mast cell tumors in 11 miniature pigs: a retrospective study
Rasche, B. L., Mozzachio, K., & Linder, K. E. (2022, February 22). JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION.
author keywords: immunohistochemistry; KIT; mast cell tumors; miniature swine; skin neoplasms
MeSH headings : Animals; Mast Cells; Mastocytoma, Skin / pathology; Mastocytoma, Skin / veterinary; Proto-Oncogene Proteins c-kit; Retrospective Studies; Skin Neoplasms / diagnosis; Skin Neoplasms / pathology; Skin Neoplasms / veterinary; Swine; Swine Diseases / diagnosis; Swine Diseases / pathology; Swine, Miniature; Tolonium Chloride
TL;DR:
KIT is a promising diagnostic marker for MCTs in miniature pigs in a retrospective descriptive study of 11 miniature pigs, and was present in tumors in all cases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 14, 2022
2022 article
Hyperkeratotic erythema multiforme variant in 17 dogs
Banovic, F., Olivry, T., Artlet, B., Rothstein, E., Beco, L., Linek, M., … Linder, K. (2022, December 12). VETERINARY DERMATOLOGY, Vol. 12.
author keywords: dog; erythema multiforme; hyperkeratotic
MeSH headings : Male; Dogs; Animals; Parakeratosis / pathology; Parakeratosis / veterinary; Dog Diseases / diagnosis; Erythema Multiforme / drug therapy; Erythema Multiforme / veterinary; Erythema Multiforme / diagnosis; Skin / pathology; Epidermis / pathology
TL;DR:
Hyperkeratotic ery thema multiforme (HKEM) is a chronic, persistent and clinically distinctive erythema multangulare (EM) variant that differs from 'classic' vesiculobullous erosive-to-ulcerative EM in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 13, 2022
2022 article
Localised erythema multiforme-like reaction confined to a region of clipper burn in a dog
Tham, H. L., Lanz, O. I., & Linder, K. E. (2022, January 19). VETERINARY DERMATOLOGY.
MeSH headings : Animals; Dog Diseases / diagnosis; Dog Diseases / etiology; Dogs; Erythema Multiforme / diagnosis; Erythema Multiforme / etiology; Erythema Multiforme / veterinary
TL;DR:
Clinical and histopathological features of LEM-like reaction in a dog, confined to a region of clipper burn are described.
(via Semantic Scholar)
Source: Web Of Science
Added: February 7, 2022
2022 article
Pulmonary exposure of mice to ammonium perfluoro(2-methyl-3-oxahexanoate) (GenX) suppresses the innate immune response to carbon black nanoparticles and stimulates lung cell proliferation
Lee, H. Y., You, D. J., Taylor-Just, A. J., Linder, K. E., Atkins, H. M., Ralph, L. M., … Bonner, J. C. (2022, June 14). INHALATION TOXICOLOGY.
author keywords: Carbon black; nanoparticles; PFAS; lung; immunity
MeSH headings : Ammonium Compounds / toxicity; Animals; Bronchoalveolar Lavage Fluid / chemistry; Cell Proliferation; Cytokines / metabolism; Fluorocarbons / toxicity; Immunity, Innate; Ki-67 Antigen / metabolism; Lung; Male; Mice; Mice, Inbred C57BL; NF-kappa B / metabolism; Nanoparticles / toxicity; Soot / toxicity
TL;DR:
Pulmonary exposure to GenX suppressed CBNP-induced innate immune response in the lungs of mice yet promoted the proliferation of macrophages and lung epithelial cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: June 27, 2022
2022 article
Trunk-dominant and classic facial pemphigus foliaceus in dogs - comparison of anti-desmocollin-1 and anti-desmoglein-1 autoantibodies and clinical presentations
Bizikova, P., Linder, K. E., & Mamo, L. B. (2022, June 7). VETERINARY DERMATOLOGY.
MeSH headings : Animals; Autoantibodies; Desmoglein 1; Dog Diseases; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Immunoglobulin G; Pemphigus / diagnosis; Pemphigus / veterinary
TL;DR:
Footpad involvement and grouped/polycyclic lesion organisation were identified as features of both PF phenotypes, and not of SP, and the ability to detect anti-DSC1 IgG is lower in trunk-dominant PF, yet despite the lower sensitivity, the positive predictive value and accuracy of this particular anti- DSC1 igG test are high.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 20, 2022
2021 article
Bullous amyloidosis in a horse: first description in veterinary medicine
Fussell, D., Bizikova, P., Breuhaus, B., Harris, R. A., Moore, A. R., Chen, L., & Linder, K. E. (2021, June 13). VETERINARY DERMATOLOGY, Vol. 6.
MeSH headings : Amyloid; Amyloidosis / diagnosis; Amyloidosis / veterinary; Animals; Blister / veterinary; Female; Horse Diseases / diagnosis; Horses; Mucous Membrane; Skin
TL;DR:
Bullous amyloidosis is a novel disease of the horse and a newly recognised differential for bullous disease, for which the haemorrhagic nature of bullae, scarring and deep secondary ulcers are considered clinical clues to the condition.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 21, 2021
2021 journal article
Canine junctional epidermolysis bullosa due to a novel mutation in LAMA3 with severe upper respiratory involvement
VETERINARY DERMATOLOGY, 32(4), 379-+.
MeSH headings : Animals; Australia; Cattle; Dog Diseases / genetics; Dogs; Epidermolysis Bullosa, Junctional / genetics; Epidermolysis Bullosa, Junctional / veterinary; Laminin / genetics; Mutation, Missense; Nail Diseases / genetics; Nail Diseases / veterinary
TL;DR:
A novel variant in LAMA3 caused a generalized and severe phenotype of JEB with an unique clinical presentation of upper airway obstruction in a litter of puppies with severe upper respiratory involvement.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 19, 2021
2021 journal article
Case Report: Pulmonary Conidiobolomycosis in a Vietnamese Pot-Bellied Pig
FRONTIERS IN VETERINARY SCIENCE, 8.
author keywords: Conidiobolus spp; entomophthoromycosis; pneumonia; domestic animal; pig
TL;DR:
Pan-fungal PCR and sequencing performed on formalin-fixed, paraffin-embedded lung tissue identified Conidiobolus spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 10, 2022
2021 article
Correlation of cytology to histology in a case of canine granulomatous colitis in a Boxer dog
Sims, C. S., Nagle, J., Tolbert, M. K., Anderson, K., Linder, K., & Neel, J. (2021, October 18). VETERINARY CLINICAL PATHOLOGY, Vol. 10.
Contributors: C. Sims n, J. Nagle n, M. Tolbert*, K. Anderson n, n & J. Neel n
author keywords: Boxer dog; canine; colitis; Escherichia coli; histiocytic colitis; rectal cytology; ulcerative colitis
MeSH headings : Animals; Crohn Disease / veterinary; Dog Diseases / diagnosis; Dogs; Hospitals, Animal; Hospitals, Teaching; In Situ Hybridization, Fluorescence / veterinary; Male
TL;DR:
The cytology was helpful in identifying features consistent with granulomatous colitis and prioritizing the differential diagnoses and diagnostic plan and is the first published description of the cytologic features of this uncommon disease, offering a valuable cytologic-histologic correlation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 1, 2021
2021 article
International Guidelines for Veterinary Tumor Pathology: A Call to Action
Meuten, D. J., Moore, F. M., Donovan, T. A., Bertram, C. A., Klopfleisch, R., Foster, R. A., … Whitley, D. (2021, July 20). VETERINARY PATHOLOGY.
author keywords: standardization; oncology; guidelines; protocols; validation
MeSH headings : Animals; Neoplasms / diagnosis; Neoplasms / veterinary; Pathology, Veterinary; Reproducibility of Results
TL;DR:
This initiative is a continuation of efforts published in this journal in 2011 and it is hoped that this initiative will facilitate collaboration and reproducibility between pathologists and institutions, increase case numbers, and strengthen clinical research findings, thus ensuring continued progress in veterinary oncologic pathology and improving patient care.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 2, 2021
2021 journal article
Surgical management and histopathology of wen overgrowth and neoplasia in four oranda goldfish (Carassius auratus)
VETERINARY RECORD CASE REPORTS, 9(1).
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 8, 2021
2021 journal article
Three-dimensional (3D) imaging of lipids in skin tissues with infrared matrix-assisted laser desorption electrospray ionization (MALDESI) mass spectrometry
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 413(10), 2793–2801.
author keywords: 3D; Mass spectrometry imaging; IR-MALDESI; Skin; Lipids
MeSH headings : Animals; Imaging, Three-Dimensional / methods; Lipids / analysis; Mice; Mice, Hairless; Skin / chemistry; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR:
The use of infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) in ablation-based 3D MSI for analyses of lipids within fresh frozen skin tissue is described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: January 25, 2021
2020 journal article
A Subset of Equine Gastric Squamous Cell Carcinomas Is Associated With Equus Caballus Papillomavirus-2 Infection
VETERINARY PATHOLOGY, 57(3), 427–431.
author keywords: horses; squamous cell carcinoma; Equus caballus papillomavirus; oncogenic viruses; stomach; in situ hybridization
MeSH headings : Animals; Carcinoma, Squamous Cell / genetics; Carcinoma, Squamous Cell / pathology; Carcinoma, Squamous Cell / veterinary; Carcinoma, Squamous Cell / virology; DNA, Viral / genetics; Horse Diseases / virology; Horses; In Situ Hybridization / veterinary; Oncogenes / genetics; Papillomaviridae / genetics; Papillomaviridae / isolation & purification; Papillomavirus Infections / pathology; Papillomavirus Infections / veterinary; Polymerase Chain Reaction / veterinary; Stomach / pathology; Stomach Neoplasms / veterinary
TL;DR:
Support is provided for a potential association between EcPV-2 infection and a subset of equine gastric SCCs by performing polymerase chain reaction (PCR) and in situ hybridization (ISH) for EcPVs E6/ E7 oncogenes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: April 20, 2020
2020 journal article
Cutaneous polyautoimmunity in two unrelated dogs: pemphigus foliaceus and generalized discoid lupus erythematosus
VETERINARY DERMATOLOGY, 31(4), 325-+.
MeSH headings : Administration, Cutaneous; Animals; Comorbidity; Cyclosporine / therapeutic use; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dogs; Lupus Erythematosus, Discoid / diagnosis; Lupus Erythematosus, Discoid / drug therapy; Lupus Erythematosus, Discoid / veterinary; Pemphigus / diagnosis; Pemphigus / drug therapy; Pemphigus / veterinary; Skin / pathology
TL;DR:
Cutaneous polyautoimmunity can occur in the dog and overlapping clinical features may present diagnostic and/or therapeutic challenges.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 18, 2020
2020 journal article
Feasibility study evaluating arrhythmogenesis and cardiac damage after heart-base irradiation in mice: A brief communication
VETERINARY MEDICINE AND SCIENCE, 6(4), 1009–1016.
author keywords: animal models; arrhythmia; radiation; radiobiology; radiotherapy
MeSH headings : Animals; Arrhythmias, Cardiac / etiology; Disease Models, Animal; Feasibility Studies; Female; Heart / radiation effects; Mice; Mice, Inbred C57BL; Myocardium / pathology; Pilot Projects
TL;DR:
While this study did not demonstrate significant arrhythmogenesis, certain modifications of the experimental mouse irradiation procedures are discussed which may enable more translationally relevant modelling of the canine cardiac response to SBRT‐like irradiation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 29, 2020
2020 journal article
Physiological response, function of sweat glands, and hair follicle cycling in cattle in response to fescue toxicosis and hair genotype
Journal of Animal Science, 98(3).
author keywords: beef heifers; hair follicle; prolactin receptor; slick hair trait; sweat gland; tall fescue
MeSH headings : Animal Feed; Animals; Cattle / genetics; Cattle / physiology; Cattle Diseases / microbiology; Cattle Diseases / physiopathology; Diet / veterinary; Endophytes / physiology; Female; Festuca / microbiology; Gene Expression Regulation; Genotype; Hair; Hair Follicle / physiology; Heat-Shock Response; Mycotoxicosis / microbiology; Mycotoxicosis / physiopathology; Mycotoxicosis / veterinary; Plant Poisoning / microbiology; Plant Poisoning / physiopathology; Plant Poisoning / veterinary; Sweat Glands / physiology
TL;DR:
EI fescue resulted in increased ST, changes in hair follicle cycling that support greater hair growth, and decreased TEWL for heifers with the W compared to S genotype suggesting greater heat stress in response to EI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: June 1, 2020
2020 journal article
Rapid response of hyperkeratotic erythema multiforme to oclacitinib in two dogs
VETERINARY DERMATOLOGY, 31(4), 330-+.
MeSH headings : Animals; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Dog Diseases / drug therapy; Dogs; Erythema Multiforme / diagnosis; Erythema Multiforme / drug therapy; Erythema Multiforme / veterinary; Female; Pyrimidines / therapeutic use; Skin Diseases / drug therapy; Skin Diseases / veterinary; Sulfonamides / therapeutic use; Treatment Outcome
TL;DR:
Oclacitinib could be considered as a fast-acting and effective treatment option for HKEM in dogs with a complete remission of clinical signs observed in 12 and seven weeks in cases 1 and 2.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: May 8, 2020
2020 journal article
Sex differences in the acute and subchronic lung inflammatory responses of mice to nickel nanoparticles
NANOTOXICOLOGY, 14(8), 1058–1081.
author keywords: Nickel nanoparticles; inflammation; lung; sex; susceptibility
MeSH headings : Animals; Bronchoalveolar Lavage Fluid / cytology; Chemokine CXCL1 / metabolism; Female; Humans; Inhalation Exposure; Interleukin-6 / metabolism; Lung / drug effects; Lung / immunology; Lung / pathology; Male; Metal Nanoparticles / toxicity; Mice; Mice, Inbred C57BL; Neutrophils / cytology; Neutrophils / drug effects; Nickel / toxicity; Pneumonia / chemically induced; Pneumonia / pathology; STAT Transcription Factors / metabolism; Sex Characteristics; Signal Transduction; Toxicity Tests, Acute; Toxicity Tests, Subchronic
TL;DR:
Sex differences in the lung inflammatory response of mice to NiNPs that has implications for human disease are demonstrated and indicate that susceptibility of males to acute lung inflammation involves enhanced neutrophilia with increased CXCL1 and IL-6/STAT3 signaling, whereas susceptibility to subchronic lunginflammation involves enhanced monocytic infiltration withIncreased CXcl1 and CCL2.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 7, 2020
2019 journal article
Autoimmune diseases affecting skin melanocytes in dogs, cats and horses: vitiligo and the uveodermatological syndrome: a comprehensive review
BMC Veterinary Research, 15(1).
author keywords: Autoimmune skin diseases; Vitiligo; Uveodermatological; Vogt-Koyanagi-Harada; Leukoderma; Depigmentation; Melanocytes; Canine; Feline; Equine; Dermatology
MeSH headings : Animal Diseases / diagnosis; Animal Diseases / etiology; Animal Diseases / therapy; Animals; Autoimmune Diseases / diagnosis; Autoimmune Diseases / therapy; Autoimmune Diseases / veterinary; Cats; Dogs; Horses; Melanocytes / pathology; Pigmentation Disorders / diagnosis; Pigmentation Disorders / etiology; Pigmentation Disorders / veterinary; Vitiligo / diagnosis; Vitiligo / etiology; Vitiligo / therapy; Vitiligo / veterinary
TL;DR:
The canine uveodermatological syndrome resembles the incomplete VKH variant in humans; for affected individuals, an immediate diagnosis and aggressive treatment are crucial to prevent the development of blindness.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 5, 2019
2019 journal article
C/EBP beta suppresses keratinocyte autonomous type 1 IFN response and p53 to increase cell survival and susceptibility to UVB-induced skin cancer
CARCINOGENESIS, 40(9), 1099–1109.
TL;DR:
A p53-C/E BPβ feedback loop, whereby C/EBPβ a transcriptional target of a p53 pathway, functions as a survival factor by negatively regulating p53 apoptotic activity in response to DNA damage is suggested.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 18, 2019
2019 journal article
The role of oclacitinib in the management of ischaemic dermatopathy in four dogs
Veterinary Dermatology, 30(3), 201–e63.
MeSH headings : Animals; Autoimmune Diseases / drug therapy; Autoimmune Diseases / veterinary; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Dermatologic Agents / administration & dosage; Dermatologic Agents / therapeutic use; Dog Diseases / drug therapy; Dogs; Female; Glucocorticoids / therapeutic use; Male; Pyrimidines / administration & dosage; Pyrimidines / therapeutic use; Skin Diseases / drug therapy; Skin Diseases / veterinary; Sulfonamides / administration & dosage; Sulfonamides / therapeutic use; Treatment Outcome
TL;DR:
Oclacitinib was a useful immunosuppressive adjuvant to oral glucocorticoids for the treatment of refractory or severe cases of ischaemic dermatopathy in these four dogs, and warrants further studies of the safety, efficacy and mechanism of action of oclac itinib as an Immunosuppressant.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: May 28, 2019
2018 journal article
Bartonella henselae in a dog with ear tip vasculitis
Veterinary Dermatology, 29(6), 537–e180.
MeSH headings : Animals; Bartonella henselae / genetics; Cat-Scratch Disease / pathology; Cat-Scratch Disease / veterinary; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Ear, External / microbiology; Ear, External / pathology; Female; Polymerase Chain Reaction / veterinary; Vasculitis / diagnosis; Vasculitis / pathology; Vasculitis / veterinary
TL;DR:
Bartonella henselae is an emerging zoonotic pathogen that has been associated with leucocytoclastic vasculitis in humans and may have had a contributing or causative role in the development of the cutaneous aural margin vasculopathy in this beagle.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: November 26, 2018
2018 journal article
Generalized papillomatosis in three horses associated with a novel equine papillomavirus (EcPV8)
Veterinary Dermatology, 29(1).
Source: NC State University Libraries
Added: August 6, 2018
2018 journal article
Hypochlorous acid is antipruritic and anti-inflammatory in a mouse model of atopic dermatitis
CLINICAL AND EXPERIMENTAL ALLERGY, 48(1), 78–88.
author keywords: atopic dermatitis; dorsal root ganglia; hypochlorous acid; IgE; IL-13; IL-4; NC; Nga mice; sensory neurons
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Antigens, Dermatophagoides / toxicity; Antipruritics / pharmacology; Cytokines / immunology; Dermatitis, Atopic / chemically induced; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / immunology; Dermatitis, Atopic / pathology; Disease Models, Animal; Female; Hypochlorous Acid / pharmacology; Inflammation / chemically induced; Inflammation / drug therapy; Inflammation / immunology; Inflammation / pathology; Mice; Mice, Inbred BALB C
TL;DR:
It has been reported that topical hypochlorous acid (HOCl) formulations lead to relief of itch in human patients with atopic dermatitis; however, the specific antipruritic mechanism of action remains unclear.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Endothelial alterations in a canine model of immune thrombocytopenia
Platelets, 30(1), 88–97.
author keywords: Dog; endothelium; ITP
MeSH headings : Animals; Biomarkers; Biopsy; Blood Coagulation; Blood Platelets / metabolism; Blood Platelets / ultrastructure; Disease Models, Animal; Dogs; Endothelium / metabolism; Endothelium / ultrastructure; Flow Cytometry; Lysophospholipids / blood; Male; Platelet Activation; Platelet Count; Purpura, Thrombocytopenic, Idiopathic / blood; Purpura, Thrombocytopenic, Idiopathic / drug therapy; Purpura, Thrombocytopenic, Idiopathic / etiology; Purpura, Thrombocytopenic, Idiopathic / metabolism; Sphingosine / analogs & derivatives; Sphingosine / blood; von Willebrand Factor / metabolism
TL;DR:
The results indicate that endothelial damage occurs in the canine ITP model and variability in the degree of endothelialDamage may account for differences in the bleeding phenotype among patients with ITP.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: March 18, 2019
2017 journal article
Evaluation of a 2-aminoimidazole variant as adjuvant treatment for dermal bacterial infections
Drug Design Development and Therapy, 11, 153–162.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Pharmacokinetics and toxicity of subcutaneous administration of carboplatin in poloxamer 407 in a rodent model pilot study
PLoS One, 12(10).
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Clinical and microscopic features of generalized discoid lupus erythematosus in dogs (10 cases)
VETERINARY DERMATOLOGY, 27(6), 488-+.
Contributors: F. Banovic n, n, M. Uri n, M. Rossi & T. Olivry n
MeSH headings : Animals; Dog Diseases / pathology; Dogs; Female; Lupus Erythematosus, Discoid / pathology; Lupus Erythematosus, Discoid / veterinary; Male; Skin / pathology
TL;DR:
Observations support the existence of a canine homologue of human GDLE, a newly recognized canine variant of chronic cutaneous lupus erythematosus that is not well characterized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Early Activation of Th2/Th22 Inflammatory and Pruritogenic Pathways in Acute Canine Atopic Dermatitis Skin Lesions
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 136(10), 1961–1969.
MeSH headings : Adaptive Immunity / immunology; Animals; Cytokines / genetics; Cytokines / immunology; Dermatitis, Atopic / immunology; Dermatophagoides farinae / immunology; Disease Models, Animal; Dogs; Female; Immunity, Innate / immunology; Inflammation / immunology; Interleukin-9 / genetics; Interleukin-9 / immunology; Interleukins / genetics; Interleukins / immunology; Male; Pruritus / immunology; Skin / immunology; Skin / pathology; Species Specificity; Th2 Cells / immunology; Time Factors; Up-Regulation / genetics
TL;DR:
Experimental acute canine house dust mite-induced AD lesions exhibit an activation of innate and adaptive immune responses and pruritogenic pathways similar to those seen in humans with acute AD, thereby validating this model to test innovative therapeutics modalities for this disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Infective endocarditis in 13 cats
Journal of Veterinary Cardiology, 18(3), 213–225.
author keywords: BAPGM; Bartonella; Duke criteria; Vegetative lesion
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / physiopathology; Cats; Endocarditis, Bacterial / diagnosis; Endocarditis, Bacterial / drug therapy; Endocarditis, Bacterial / physiopathology; Endocarditis, Bacterial / veterinary; Female; Male; Prognosis; Retrospective Studies; Treatment Outcome
TL;DR:
In contrast to dogs, cats with IE typically present with clinical signs consistent with cardiac decompensation and locomotor abnormalities suggestive of either thromboembolic disease or inflammatory arthritis, and prognosis is grave.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Initial characterization of stiff skin-like syndrome in West Highland white terriers
VETERINARY DERMATOLOGY, 27(3), 210-+.
TL;DR:
The clinical phenotype and histopathological features of two West Highland white terrier siblings resembled stiff skin syndrome in humans and genetic analysis did not detect a candidate causative variant and warrants further research.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Mucous membrane pemphigoid in dogs: A retrospective study of 16 new cases
Veterinary Dermatology, 27(5), 376-.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Scanning technology selection impacts acceptability and usefulness of image-rich content
JOURNAL OF THE MEDICAL LIBRARY ASSOCIATION, 104(1), 15–23.
Contributors: K. Alpi n, J. Brown n, J. Neel n , C. Grindem n, n & J. Harper n
author keywords: Interlibrary Loans; Photographs; Image Enhancement; Image Compression; Pathology; Radiology
MeSH headings : Diagnostic Imaging / standards; Documentation / standards; Electronic Health Records / standards; Humans; Interlibrary Loans / standards; Libraries, Medical / standards; Microscopy, Electron, Scanning / standards; Photography / standards; United States
TL;DR:
This study addressed whether scans of figures in black and white, grayscale, or color, or portable document format to tagged image file format (TIFF) conversions as provided by interlibrary loan or document delivery were viewed as acceptable or useful by radiologists or pathologists.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2015 journal article
Canine epidermolysis bullosa acquisita: A retrospective study of 20 cases
Veterinary Dermatology, 26(6), 441-.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Clinical, histopathological and immunohistochemical characterization of a novel equine ocular disorder: heterochromic iridocyclitis with secondary keratitis in adult horses
VETERINARY OPHTHALMOLOGY, 18(6), 443–456.
author keywords: endotheliitis; iridocyclitis; keratic precipitates; keratitis; retrocorneal membrane; uveitis
MeSH headings : Animals; Cornea / pathology; Female; Horse Diseases / diagnosis; Horse Diseases / pathology; Horses; Iridocyclitis / diagnosis; Iridocyclitis / pathology; Iridocyclitis / veterinary; Keratitis / diagnosis; Keratitis / pathology; Keratitis / veterinary; Male; Uvea / pathology
TL;DR:
Heterochromic iridocyclitis with secondary keratitis (HIK) is characterized by uveal inflammation with pigment dispersion and suspected corneal endothelial dysfunction and may not respond to therapy and enucleation may ultimately be required to ensure the horse's comfort.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Dinotefuran/pyriproxyfen/permethrin pemphigus-like drug reaction in three dogs
Veterinary Dermatology, 26(3), 206-.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Generalized Canine Discoid Lupus Erythematosus Responsive to Tetracycline and Niacinamide Therapy
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 51(3), 171–175.
Contributors: M. Rossi n, L. Messenger n, n & T. Olivry n
MeSH headings : Animals; Dog Diseases / drug therapy; Dogs; Drug Therapy, Combination; Immunomodulation / drug effects; Lupus Erythematosus, Discoid / drug therapy; Lupus Erythematosus, Discoid / veterinary; Male; Niacinamide / therapeutic use; Protein Synthesis Inhibitors / therapeutic use; Tetracycline / therapeutic use; Vitamin B Complex / therapeutic use
TL;DR:
An 11 yr old shih tzu that presented with skin lesions consisting of multiple annular, erythematous papules and plaques, hyperpigmentation, adherent scaling, and atrophic scars over the caudal dorsum, flanks, craniodorsal thorax, and lateroproximal extremities is described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Mucocutaneous lupus erythematosus in dogs (21 cases)
VETERINARY DERMATOLOGY, 26(4), 256-+.
Contributors: T. Olivry n , M. Rossi, F. Banovic n & n
MeSH headings : Animals; Biopsy / veterinary; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Female; Glucocorticoids / therapeutic use; Lupus Erythematosus, Cutaneous / diagnosis; Lupus Erythematosus, Cutaneous / drug therapy; Lupus Erythematosus, Cutaneous / pathology; Lupus Erythematosus, Cutaneous / veterinary; Male; Sex Factors; Skin / pathology
TL;DR:
Observations support MCLE being another variant of canine CLE, a variant of cutaneous lupus erythematosus that affected mostly dogs in their mid-adulthood and there was an over-representation of females.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Prevalence of Bartonella spp. in Canine Cutaneous Histiocytoma
Journal of Comparative Pathology, 153(1), 14–21.
author keywords: Bartonella; canine cutaneous histiocytoma; dog
MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Dog Diseases / microbiology; Dogs; Histiocytoma, Benign Fibrous / microbiology; Histiocytoma, Benign Fibrous / veterinary; Prevalence; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms / microbiology; Skin Neoplasms / veterinary
TL;DR:
It is hypothesized that Bartonella spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Protozoal nodular dermatitis and panniculitis in a Rottweiler puppy caused by Caryospora bigenetica
Veterinary Dermatology, 27(1), 44–e12.
MeSH headings : Animals; Anti-Infective Agents / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / parasitology; Dogs; Eimeriidae / genetics; Eimeriidae / isolation & purification; Female; Protozoan Infections, Animal / parasitology; Protozoan Infections, Animal / pathology; Skin Diseases, Parasitic / drug therapy; Skin Diseases, Parasitic / parasitology; Skin Diseases, Parasitic / pathology; Skin Diseases, Parasitic / veterinary
TL;DR:
This is the first documentation of the treatment and outcome of C. bigenetica cutaneous infection in a dog and although remission of clinical signs can be achieved with combination therapy of clindamycin and TMS, long-term management is challenging and relapses should be anticipated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Canine hereditary ataxia in Old English Sheepdogs and Gordon Setters is associated with a defect in the autophagy gene encoding RAB24
PLoS Genetics, 10(2).
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Ciclosporin therapy for canine generalized discoid lupus erythematosus refractory to doxycycline and niacinamide
VETERINARY DERMATOLOGY, 25(5), 483–E79.
Contributors: F. Banovic n, T. Olivry n & n
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / therapeutic use; Antifungal Agents / administration & dosage; Antifungal Agents / therapeutic use; Cyclosporine / administration & dosage; Cyclosporine / therapeutic use; Dermatologic Agents / administration & dosage; Dermatologic Agents / therapeutic use; Dog Diseases / drug therapy; Dogs; Doxycycline / administration & dosage; Doxycycline / therapeutic use; Drug Therapy, Combination / veterinary; Ketoconazole / administration & dosage; Ketoconazole / therapeutic use; Lupus Erythematosus, Discoid / drug therapy; Lupus Erythematosus, Discoid / veterinary; Male; Niacinamide / administration & dosage; Niacinamide / therapeutic use; Treatment Failure; Treatment Outcome
TL;DR:
The combination of ciclosporin and ketoconazole appeared effective to induce and maintain lesion remission in this dog with generalized DLE.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2014 journal article
Clinical and Microscopic Characteristics of Canine Toxic Epidermal Necrolysis
Veterinary Pathology, 52(2), 321–330.
Contributors: F. Banovic n, T. Olivry n , L. Bazzle n, J. Tobias n, B. Atlee, S. Zabel*, N. Hensel*, n
author keywords: ALDEN; Canis familiaris; carprofen; drug reaction; erythema multiforme; skin; toxic epidermal necrolysis
MeSH headings : Animals; Apoptosis; Biopsy / veterinary; Disease Progression; Dog Diseases / pathology; Dogs; Drug-Related Side Effects and Adverse Reactions / veterinary; Epidermis / pathology; Female; Necrosis / veterinary; Stevens-Johnson Syndrome / pathology; Stevens-Johnson Syndrome / veterinary
TL;DR:
Clinically, irregular erythematous and purpuric macules evolved into widespread and severely painful erosions, and the sequence of changes points to lymphocyte-mediated keratinocyte apoptosis as an early step in lesion development with subsequent variation in progression to coagulation necrosis among patients.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID
Added: July 21, 2019
2014 journal article
ConcurrentBartonella henselaeinfection in a dog with panniculitis and owner with ulcerated nodular skin lesions
Veterinary Dermatology, 26(1), 60–e22.
MeSH headings : Aged; Angiomatosis, Bacillary / diagnosis; Angiomatosis, Bacillary / pathology; Angiomatosis, Bacillary / transmission; Angiomatosis, Bacillary / veterinary; Animals; Bartonella henselae; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dog Diseases / transmission; Dogs; Female; Humans; Male; Skin / pathology; Skin Ulcer / microbiology; Zoonoses / diagnosis; Zoonoses / microbiology; Zoonoses / pathology
TL;DR:
B Bartonella henselae is an emerging zoonotic pathogen that induces granulomatous inflammatory lesions in various tissues of animals, including humans, and is concluded that this bacterium had a contributory or causative role in the development of the dermatological lesions in the dog and owner.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Fipronil-amitraz-S-methoprene-triggered pemphigus foliaceus in 21 dogs: clinical, histological and immunological characteristics
Veterinary Dermatology, 25(2), 103–e30.
Contributors: P. Bizikova n, n & T. Olivry n
MeSH headings : Animals; Dog Diseases / chemically induced; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Drug Combinations; Female; Insecticides / administration & dosage; Insecticides / adverse effects; Insecticides / therapeutic use; Male; Methoprene / administration & dosage; Methoprene / adverse effects; Methoprene / therapeutic use; Pemphigus / chemically induced; Pemphigus / immunology; Pemphigus / pathology; Pemphigus / veterinary; Pyrazoles / administration & dosage; Pyrazoles / adverse effects; Pyrazoles / therapeutic use; Toluidines / administration & dosage; Toluidines / adverse effects; Toluidines / therapeutic use
TL;DR:
This new topical ectoparasiticide containing fipronil, amitraz and S-methoprene is capable of triggering the development of an acantholytic pustular dermatosis that is a clinical, histological and immunological close match for Promeris-triggered PF and naturally occurring autoimmune PF in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, ORCID, NC State University Libraries
Added: July 21, 2019
2014 article
Pathology in Practice
Banovic, F., Olivry, T., Linder, K. E., & Tobias, J. R. (2014, December 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 245, pp. 1237–1239.
MeSH headings : Animals; Anti-Inflammatory Agents / administration & dosage; Anti-Inflammatory Agents / therapeutic use; Cyclosporine / administration & dosage; Cyclosporine / adverse effects; Cyclosporine / therapeutic use; Dog Diseases / pathology; Dogs; Drug Eruptions / pathology; Drug Eruptions / veterinary; Drug Therapy, Combination; Female; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / adverse effects; Immunosuppressive Agents / therapeutic use; Lupus Erythematosus, Cutaneous / drug therapy; Lupus Erythematosus, Cutaneous / pathology; Lupus Erythematosus, Cutaneous / veterinary; Prednisolone / administration & dosage; Prednisolone / therapeutic use
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
The Effect of Photodynamic Therapy on Cisterna Chyli Patency in Rats
VETERINARY SURGERY, 43(6), 642–649.
MeSH headings : Animals; Dose-Response Relationship, Drug; Injections; Lymph Nodes; Lymphography; Male; Photochemotherapy; Photosensitizing Agents / pharmacology; Phytotherapy; Porphyrins / pharmacology; Rats; Rats, Sprague-Dawley; Thoracic Duct / diagnostic imaging; Thoracic Duct / drug effects; Thoracic Duct / pathology; Verteporfin
TL;DR:
Investigations into the timing of laser application and light dose, or alternative photodynamic agents are required to limit injury to adjacent tissues and to improve the effectiveness of cisternal photoablation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Cat scratch-induced Pasteurella multocida necrotizing cellulitis in a dog
Veterinary Dermatology, 24(4), 463–e108.
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Carbazoles / therapeutic use; Cat-Scratch Disease / microbiology; Cat-Scratch Disease / pathology; Cat-Scratch Disease / veterinary; Cellulitis / etiology; Cellulitis / microbiology; Cellulitis / pathology; Cellulitis / veterinary; Dog Diseases; Dogs; Female; Pasteurella Infections / microbiology; Pasteurella Infections / veterinary; Pasteurella multocida; Skin Transplantation / veterinary
TL;DR:
This case highlights the rapidity and severity of P. multocida cellulitis, if not recognized and treated early, and should be included in the differential diagnosis of any local wound infection following a cat scratch.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: August 30, 2019
2013 journal article
Experimental infection of dogs with Bartonella henselae and Bartonella vinsonii subsp. berkhoffii
Veterinary Immunology and Immunopathology, 156(1-2), 153–158.
author keywords: PCR; Bacteria; Bartonella henselae SA2; Bartonella vinsonii subsp berkhoffii genotype III; Isolation; Dog model
MeSH headings : Animals; Antibodies, Bacterial / blood; Bacteremia / immunology; Bacteremia / microbiology; Bacteremia / veterinary; Bartonella Infections / immunology; Bartonella Infections / microbiology; Bartonella henselae / immunology; DNA, Bacterial / analysis; Dog Diseases / immunology; Dog Diseases / microbiology; Dogs
TL;DR:
Following intradermal infection, sequestration of Bartonella spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2013 journal article
Koch's Postulates and the Pathogenesis of Comparative Infectious Disease Causation Associated with Bartonella species
Journal of Comparative Pathology, 148(2-3), 115–125.
author keywords: disease; infection; pathology; Koch's postulates
TL;DR:
Recent research observations involving the genus Bartonella are used to propose an additional postulate of comparative infectious disease causation to Koch's postulates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, Web Of Science, NC State University Libraries
Added: August 6, 2018
2013 journal article
Lichenoid psoriasifrom dermatitis
Journal of the American Veterinary Medical Association, 245(11), 1237–1239.
Source: NC State University Libraries
Added: August 30, 2019
2013 journal article
Necrolytic migratory erythema associated with a glucagon-producing primary hepatic neuroendocrine carcinoma in a cat
VETERINARY DERMATOLOGY, 24(4), 466–E110.
MeSH headings : Animals; Carcinoma, Neuroendocrine / complications; Carcinoma, Neuroendocrine / pathology; Carcinoma, Neuroendocrine / veterinary; Cat Diseases / etiology; Cat Diseases / pathology; Cats; Glucagon / metabolism; Liver Neoplasms / complications; Liver Neoplasms / pathology; Liver Neoplasms / veterinary; Male; Necrolytic Migratory Erythema / etiology; Necrolytic Migratory Erythema / pathology; Necrolytic Migratory Erythema / veterinary
TL;DR:
This is the first case report of NME associated with a glucagon-producing primary hepatic neuroendocrine carcinoma in a cat and it was euthanized 11 months after the initial presentation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Polyomavirus-Associated Nephritis in 2 Horses
Veterinary Pathology, 50(5), 769–774.
author keywords: kidney; horse; myocarditis; nephritis; polyomavirus
MeSH headings : Animals; Blood Chemical Analysis / veterinary; Capsid Proteins / genetics; DNA Primers / genetics; Fatal Outcome; Female; Horse Diseases / immunology; Horse Diseases / pathology; Horse Diseases / virology; Horses; Immunocompromised Host / immunology; Immunoglobulin G / blood; Immunohistochemistry / veterinary; Kidney Cortex Necrosis / pathology; Kidney Cortex Necrosis / veterinary; Kidney Cortex Necrosis / virology; Male; Nephritis, Interstitial / pathology; Nephritis, Interstitial / veterinary; Nephritis, Interstitial / virology; Phylogeny; Polyomavirus / genetics; Polyomavirus Infections / pathology; Polyomavirus Infections / veterinary
TL;DR:
2 Standardbred horses with tubular necrosis and tubulointerstitial nephritis associated with productive equine polyomvirus infection that resembles BK polyomavirus nephropathy in immunocompromised humans are described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2013 journal article
What Is Your Diagnosis?
Journal of the American Veterinary Medical Association, 242(3), 311–313.
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Horse Diseases / diagnosis; Horse Diseases / pathology; Horse Diseases / therapy; Horses; Lymphedema / diagnosis; Lymphedema / pathology; Lymphedema / therapy; Lymphedema / veterinary; Male
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
A Case of Enzootic Nasal Adenocarcinoma in a Ewe
Case Reports in Veterinary Medicine, 2012, 1–4.
TL;DR:
An approximately 2-year-old open Suffolk ewe presented to the North Carolina State University College of Veterinary Medicine Veterinary Health Complex for evaluation of a left nasal mass, and IHC and RT-PCR identified the presence of enzootic nasal tumor virus and confirmed the final diagnosis of enzooting nasal adenocarcinoma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 20, 2019
2012 journal article
Bartonella vinsonii subsp. berkhoffii and Bartonella henselae as potential causes of proliferative vascular diseases in animals
Medical Microbiology and Immunology, 201(3), 319–326.
author keywords: Infection; Pathology; Systemic angiomatosis; Hemangiopericytoma; Bacteria
MeSH headings : Angiomatosis, Bacillary / microbiology; Angiomatosis, Bacillary / pathology; Angiomatosis, Bacillary / veterinary; Animals; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae / classification; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Cat Diseases / microbiology; Cat Diseases / pathology; Cats; Cattle; Cattle Diseases / microbiology; Cattle Diseases / pathology; DNA, Bacterial / analysis; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; HeLa Cells; Hemangiopericytoma / microbiology; Hemangiopericytoma / pathology; Hemangiopericytoma / veterinary; Humans; Polymerase Chain Reaction / methods
TL;DR:
It is suggested that a fourth species, B. vinsonii subsp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2012 journal article
Bilaterally Symmetrical Alopecia With Reticulated Hyperpigmentation
Veterinary Pathology, 50(4), 682–685.
Contributors: T. Olivry n & n
author keywords: alopecia; autoimmunity; dog diseases; hair follicle; lupus
MeSH headings : Alopecia / immunology; Alopecia / pathology; Alopecia / veterinary; Animals; Autoimmunity; Biopsy; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Folliculitis / immunology; Folliculitis / pathology; Folliculitis / veterinary; Hair Follicle / pathology; Hyperpigmentation / immunology; Hyperpigmentation / pathology; Hyperpigmentation / veterinary; Lupus Erythematosus, Discoid / immunology; Lupus Erythematosus, Discoid / pathology; Lupus Erythematosus, Discoid / veterinary; Lupus Erythematosus, Systemic / immunology; Lupus Erythematosus, Systemic / pathology; Lupus Erythematosus, Systemic / veterinary; Male; Skin / pathology
TL;DR:
An adult castrated male Doberman Pinscher was presented with a 6-month history of well-demarcated alopecic patches with reticulated hyperpigmentation and fine peripheral scaling, eventually associated with the development of systemic lupus erythematosus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID
Added: July 21, 2019
2012 journal article
Characterization of the origin and body of the normal equine rear suspensory ligament using ultrasonography, magnetic resonance imaging, and histology
Veterinary Radiology & Ultrasound, 53(3), 318–328.
MeSH headings : Animals; Hindlimb / anatomy & histology; Hindlimb / diagnostic imaging; Histological Techniques / veterinary; Horses / anatomy & histology; Ligaments / anatomy & histology; Magnetic Resonance Imaging / veterinary; Ultrasonography / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Crossref
Added: August 30, 2019
2012 journal article
Deficient Plakophilin-1 Expression Due to a Mutation in PKP1 Causes Ectodermal Dysplasia-Skin Fragility Syndrome in Chesapeake Bay Retriever Dogs
PLoS ONE, 7(2), e32072.
Contributors: T. Olivry n , n, P. Wang *, P. Bizikova n, J. Bernstein, S. Dunston n, J. Paps n, M. Casal *
Ed(s): J. Brandner
MeSH headings : Animals; DNA Primers / genetics; Desmosomes / metabolism; Disease Models, Animal; Dogs; Ectodermal Dysplasia / genetics; Gene Expression Regulation; Keratins / chemistry; Microscopy, Electron / methods; Microscopy, Electron, Transmission / methods; Mutation; Phenotype; Plakophilins / biosynthesis; Plakophilins / genetics; Sequence Analysis, DNA / methods; Skin / pathology; Skin Diseases / genetics; Skin Diseases / metabolism
TL;DR:
The clinical and pathological findings, along with the PKP1 mutation, were consistent with the diagnosis of ectodermal dysplasia-skin fragility syndrome with plakophilin-1 deficiency, a novel congenital acantholytic dermatosis that developed in Chesapeake Bay retriever dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Crossref, ORCID, NC State University Libraries
Added: July 21, 2019
2012 journal article
Infection of human brain vascular pericytes (HBVPs) by Bartonella henselae
Medical Microbiology and Immunology, 202(2), 143–151.
author keywords: Blood vessels; Bacteria; Cytokines; Vascular endothelial growth factor; Pericyte coverage
MeSH headings : Angiomatosis, Bacillary / metabolism; Angiomatosis, Bacillary / microbiology; Apoptosis; Bartonella henselae / physiology; Brain / metabolism; Brain / microbiology; Brain / pathology; Cell Proliferation; Cells, Cultured; Humans; Pericytes / metabolism; Pericytes / microbiology; Pericytes / ultrastructure; Vascular Endothelial Growth Factor A / biosynthesis
TL;DR:
After infecting human brain vascular pericytes with Bartonella henselae, it was found that these bacteria were able to invade HBVPs and that bacterial infection resulted in decreased pericyte proliferation and increased pericyter production of vascular endothelial growth factor (VEGF) when compared to the uninfected control cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2012 journal article
LACK OF HYDROXYLATED FULLERENE TOXICITY AFTER INTRAVENOUS ADMINISTRATION TO FEMALE SPRAGUE-DAWLEY RATS
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 75(7), 367–373.
Contributors: N. Monteiro-Riviere n , n, A. Inman n, J. Saathoff n, X. Xia n & J. Riviere n
MeSH headings : Animals; Blood Chemical Analysis; Drug Administration Schedule; Female; Fullerenes / administration & dosage; Fullerenes / chemistry; Fullerenes / toxicity; Injections, Intravenous; Liver / drug effects; Lymphocytes / drug effects; Nanoparticles / administration & dosage; Nanoparticles / chemistry; Nanoparticles / toxicity; Rats; Rats, Sprague-Dawley; Thymus Gland / drug effects; Toxicity Tests, Acute; Urinalysis
TL;DR:
These experiments suggest that this fullerol was well tolerated after iv administration to rats, and no clinically significant chemistry changes were observed after treatment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Mapping of Purkinje Neuron Loss and Polyglucosan Body Accumulation in Hereditary Cerebellar Degeneration in Scottish Terriers
VETERINARY PATHOLOGY, 49(5), 852–859.
author keywords: dog; cerebellar abiotrophy; cerebellar ataxia; cerebellar cortex; inclusion; molecular layer; polyglucosan body
MeSH headings : Aging / pathology; Animals; Case-Control Studies; Cerebellar Cortex / metabolism; Cerebellar Cortex / pathology; Cerebellar Cortex / ultrastructure; Cerebellum / metabolism; Cerebellum / pathology; Cerebellum / ultrastructure; Dog Diseases / genetics; Dog Diseases / metabolism; Dog Diseases / pathology; Dogs; Female; Glucans / metabolism; Immunohistochemistry / veterinary; Inclusion Bodies / metabolism; Inclusion Bodies / pathology; Inclusion Bodies / ultrastructure; Male; Microscopy, Electron, Transmission / veterinary; Purkinje Cells / metabolism; Purkinje Cells / pathology; Purkinje Cells / ultrastructure; Spinocerebellar Degenerations / genetics; Spinocerebellar Degenerations / metabolism; Spinocerebellar Degenerations / pathology; Spinocerebellar Degenerations / veterinary
TL;DR:
Significant Purkinje cell loss and increased polyglucosan bodies in the cerebellum of affected Scottish Terriers are demonstrated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 article
Pathology in Practice
Stevens, B. J., & Linder, K. E. (2012, September 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 241, pp. 567–569.
MeSH headings : Animals; Cat Diseases / drug therapy; Cat Diseases / pathology; Cats; Ear / pathology; Immunosuppressive Agents / therapeutic use; Male; Necrosis / drug therapy; Necrosis / pathology; Necrosis / veterinary; Otitis Externa / drug therapy; Otitis Externa / pathology; Otitis Externa / veterinary; Tacrolimus / therapeutic use; Treatment Outcome
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Proliferative and necrotizing otitis externa
Journal of the American Veterinary Medical Association, 241(5), 567–569.
Source: NC State University Libraries
Added: September 8, 2019
2012 journal article
Successful treatment of a novel generalized variant of canine discoid lupus erythematosus with oral hydroxychloroquine
VETERINARY DERMATOLOGY, 23(1), 65–E16.
Contributors: U. Oberkirchner, n & T. Olivry n
MeSH headings : Administration, Oral; Animals; Antirheumatic Agents / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Female; Hydroxychloroquine / therapeutic use; Lupus Erythematosus, Discoid / drug therapy; Lupus Erythematosus, Discoid / pathology; Lupus Erythematosus, Discoid / veterinary; Treatment Outcome
TL;DR:
A generalized variant of canine DLE successfully treated with the antimalarial immunomodulator hydroxychloroquine (HCQ) mirrored the generalized discoid variant of chronic cutaneous lupus erythematosus of humans, and the apparent benefit of HCQ, its safety and low cost warrant future investigations of its use for treatment of canine cutaneouslupus variants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Surgical treatment of a pulmonary artery vascular hamartoma in a dog
Journal of the American Veterinary Medical Association, 240(7), 858–862.
MeSH headings : Animals; Dog Diseases / pathology; Dog Diseases / surgery; Dogs; Hamartoma / surgery; Hamartoma / veterinary; Male; Pulmonary Artery / pathology; Pulmonary Artery / surgery; Vascular Neoplasms / pathology; Vascular Neoplasms / surgery; Vascular Neoplasms / veterinary
TL;DR:
Computed tomography was helpful in predicting the resectability of the intracardiac mass in this dog, and treatment with arteriotomy under inflow occlusion and mild hypothermia resulted in a favorable outcome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, Web Of Science
Added: August 6, 2018
2012 journal article
Thermal dose fractionation affects tumour physiological response
INTERNATIONAL JOURNAL OF HYPERTHERMIA, 28(5), 431–440.
author keywords: thermal dosimetry; tumor oxygenation; microenvironment
MeSH headings : Animals; Antigens, Neoplasm / metabolism; Carbonic Anhydrases / metabolism; Caspase 3 / metabolism; Dogs; Hyperthermia, Induced; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; Sarcoma / metabolism; Sarcoma / pathology; Sarcoma / therapy; Soft Tissue Neoplasms / metabolism; Soft Tissue Neoplasms / pathology; Soft Tissue Neoplasms / therapy; Tumor Burden; Vascular Endothelial Growth Factor A / metabolism
TL;DR:
There was a greater reduction in tumour volume and water diffusion at the end of therapy in tumours receiving one hyperthermia fraction per week, and response data pointed to a one per week prescription being superior.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Uropathogenic E. coli Promote a Paracellular Urothelial Barrier Defect Characterized by Altered Tight Junction Integrity, Epithelial Cell Sloughing and Cytokine Release
Journal of Comparative Pathology, 147(1), 11–19.
author keywords: cytokine; tight junction; urinary tract infection; urothelial permeability
MeSH headings : Animals; Cell Membrane Permeability / physiology; Cytokines / metabolism; Diffusion Chambers, Culture; Dogs; Electric Conductivity; Epithelial Cells / metabolism; Epithelial Cells / microbiology; Epithelial Cells / pathology; Tight Junctions / pathology; Tight Junctions / ultrastructure; Tissue Culture Techniques; Urinary Bladder / metabolism; Urinary Bladder / microbiology; Urinary Bladder / pathology; Uropathogenic Escherichia coli / physiology; Urothelium / metabolism; Urothelium / microbiology; Urothelium / pathology
TL;DR:
A potential role for IL-15 is pointed to in UTI-induced urothelial injury after changes in both tissue ultrastructure and TER indicated that uropathogenic E. coli infection promotes a paracellular permeability defect associated with the failure of umbrella cell tight junction formation and umbrella cell sloughing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 21, 2019
2012 journal article
VESICULOBULLOUS SKIN REACTION TEMPORALLY RELATED TO FIROCOXIB TREATMENT IN A WHITE RHINOCEROS (CERATOTHERIUM SIMUM)
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 43(1), 186–189.
author keywords: Adverse drug reaction; Ceratotherium simum; firocoxib; vesiculobullous dermatitis; white rhinoceros
MeSH headings : 4-Butyrolactone / adverse effects; 4-Butyrolactone / analogs & derivatives; 4-Butyrolactone / therapeutic use; Animals; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Drug Eruptions / veterinary; Female; Lameness, Animal / drug therapy; Perissodactyla; Skin Diseases, Vesiculobullous / chemically induced; Skin Diseases, Vesiculobullous / veterinary; Sulfones / adverse effects; Sulfones / therapeutic use
TL;DR:
Findings in the lesions of chronic nail-bed abscesses in a 40 yr-old female white rhinoceros are similar to those seen in some drug reactions in people; therefore an adverse drug reaction to the firocoxib was suspected.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Validation of a novel epicutaneous delivery system for patch testing of house dust mite-hypersensitive dogs
Veterinary Dermatology, 23(6).
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Congenital peritoneopericardial diaphragmatic hernia in an alpaca
Australian Veterinary Journal, 89(1-2), 51–54.
author keywords: abdominal pain; alpacas; camelids; coeliotomy; diaphragmatic hernia; zoo animals
MeSH headings : Abdominal Pain / etiology; Abdominal Pain / surgery; Abdominal Pain / veterinary; Animals; Animals, Zoo; Camelids, New World; Fatal Outcome; Hernia, Diaphragmatic / surgery; Hernia, Diaphragmatic / veterinary; Hernias, Diaphragmatic, Congenital; Laparotomy / veterinary; Male; Postoperative Complications / veterinary
TL;DR:
The alpaca died soon after surgery from post-surgical complications and a peritoneopericardial diaphragmatic hernia that was not diagnosed until necropsy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: August 6, 2018
2011 journal article
Establishment and Characterization of a Canine Soft Tissue Sarcoma Cell Line
VETERINARY PATHOLOGY, 48(2), 482–485.
author keywords: dog; domestic mammals; species; immunohistochemistry; technology; cell culture; technology; oncology; disease process
MeSH headings : Animals; Cell Line, Tumor; Chromosomes, Mammalian / genetics; Dog Diseases / pathology; Dogs; Immunohistochemistry / veterinary; Male; Mice; Mice, Nude; Microscopy, Fluorescence / veterinary; Sarcoma / pathology; Sarcoma / veterinary
TL;DR:
The establishment of a new canine soft tissue sarcoma cell line (MBSa1) derived from a high-grade, metastatic neurofibrosarcoma resulting in a large number of in vitro passages coupled with solid tumor formation in athymic nude mice demonstrates that MBSa 1 has been immortalized and is tumorigenic.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Identification of Bartonella henselae in 2 Cats With Pyogranulomatous Myocarditis and Diaphragmatic Myositis
Veterinary Pathology, 49(4), 608–611.
author keywords: Bartonella; cats; diaphragmatic myositis; myocarditis
MeSH headings : Animals; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae; Cat Diseases / microbiology; Cat Diseases / pathology; Cats; Fatal Outcome; Female; Male; Myocarditis / pathology; Myocarditis / veterinary; Myositis / pathology; Myositis / veterinary
TL;DR:
This study supports a potential association between B. henselae and what has been historically described as “transmissible myocarditis and diaphragmitis” of undetermined cause in cats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2011 journal article
Immunomapping of desmosomal and nondesmosomal adhesion molecules in healthy canine footpad, haired skin and buccal mucosal epithelia: comparison with canine pemphigus foliaceus serum immunoglobulin G staining patterns
VETERINARY DERMATOLOGY, 22(2), 132–142.
Contributors: P. Bizikova n, n & T. Olivry n
MeSH headings : Animals; Cell Adhesion Molecules / analysis; Desmosomal Cadherins / analysis; Dog Diseases / blood; Dog Diseases / immunology; Dog Diseases / metabolism; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Foot; Immunoglobulin G / blood; Mouth Mucosa / immunology; Mouth Mucosa / metabolism; Pemphigus / blood; Pemphigus / immunology; Pemphigus / metabolism; Pemphigus / veterinary; Skin / immunology; Skin / metabolism
TL;DR:
The immunological heterogeneity of cPF immunoglobulin G autoantibodies is confirmed and the major indirect immunofluorescence staining pattern and the inability of most cPF sera to label the buccal mucosa closely matched that of desmocollin-1.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
Metaflumizone-amitraz (Promeris)-associated pustular acantholytic dermatitis in 22 dogs: evidence suggests contact drug-triggered pemphigus foliaceus
VETERINARY DERMATOLOGY, 22(5), 436–448.
Contributors: U. Oberkirchner, n, S. Dunston*, P. Bizikova* & T. Olivry n
MeSH headings : Administration, Topical; Animals; Apoptosis / drug effects; Apoptosis / physiology; Caspase 3 / metabolism; Dog Diseases / chemically induced; Dog Diseases / drug therapy; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Female; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / therapeutic use; Insecticides / administration & dosage; Insecticides / adverse effects; Keratinocytes / enzymology; Male; Pemphigus / chemically induced; Pemphigus / drug therapy; Pemphigus / veterinary; Semicarbazones / administration & dosage; Semicarbazones / adverse effects; Skin / pathology; Toluidines / administration & dosage; Toluidines / adverse effects
TL;DR:
PD has the potential of triggering a variant of PF that resembles spontaneously occurring autoimmune PF at clinical, morphological, immunological and treatment outcome levels.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
Molecular Prevalence of Bartonella, Babesia, and Hemotropic Mycoplasma sp. in Dogs with Splenic Disease
Journal of Veterinary Internal Medicine, 25(6), 1284–1291.
author keywords: Cancer; Endothelium; Histiocytes; Spleen
MeSH headings : Animals; Babesia / isolation & purification; Babesiosis / veterinary; Bartonella / isolation & purification; Bartonella Infections / veterinary; Biopsy / veterinary; Dog Diseases / microbiology; Dog Diseases / parasitology; Dog Diseases / pathology; Dogs; Female; Male; Mycoplasma / classification; Mycoplasma Infections / veterinary; Paraffin Embedding; Spleen / microbiology; Spleen / parasitology; Splenic Diseases / microbiology; Splenic Diseases / parasitology; Splenic Diseases / pathology; Splenic Diseases / veterinary
TL;DR:
The higher prevalence of Bartonella sp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: July 21, 2019
2011 journal article
Recognizing and treating ProMeris-triggered pemphigus foliaceus in dogs
Veterinary Medicine, 106(6), 284.
Source: NC State University Libraries
Added: September 8, 2019
2010 journal article
C/EBP alpha and C/EBP beta Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin
PLOS ONE, 5(3).
MeSH headings : Animals; CCAAT-Enhancer-Binding Protein-alpha / physiology; CCAAT-Enhancer-Binding Protein-beta / physiology; Cell Cycle; Cell Differentiation; Cell Proliferation; Epithelial Cells / cytology; Gene Expression Regulation; Genotype; Homozygote; Immunoblotting; Immunohistochemistry / methods; Keratinocytes / cytology; Mice; Sebaceous Glands / cytology; Skin / cytology
TL;DR:
Results indicate that in adult mouse skin, C/EBPα and C-EBPβ are critically involved in regulating sebocyte differentiation and epidermal homeostasis involving the basal to spinous keratinocyte transition and basal cell cycle withdrawal.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2010 journal article
Effect of a novel topical diester glucocorticoid spray on immediate- and late-phase cutaneous allergic reactions in Maltese-beagle atopic dogs: a placebo-controlled study
Veterinary Dermatology, 21(1), 71–80.
Contributors: P. Bizikova n, n, J. Paps n & T. Olivry n
MeSH headings : Administration, Topical; Animals; Anti-Inflammatory Agents / administration & dosage; Anti-Inflammatory Agents / therapeutic use; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dog Diseases / drug therapy; Dogs; Female; Histamine / adverse effects; Hydrocortisone / administration & dosage; Hydrocortisone / analogs & derivatives; Hydrocortisone / therapeutic use; Hypersensitivity, Delayed / chemically induced; Hypersensitivity, Delayed / drug therapy; Hypersensitivity, Delayed / veterinary; Hypersensitivity, Immediate / chemically induced; Hypersensitivity, Immediate / drug therapy; Hypersensitivity, Immediate / veterinary; Inflammation / drug therapy; Inflammation / pathology; Inflammation / veterinary; Intradermal Tests; Male; Skin / pathology; Skin Tests
TL;DR:
The inhibitory effect of 0.0584% hydrocortisone aceponate spray significantly decreased immediate- and late-phase IDT reactions, and prolonged application caused skin atrophy at treated sites.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, ORCID
Added: July 21, 2019
2010 journal article
Hereditary Cerebellar Degeneration in Scottish Terriers
JOURNAL OF VETERINARY INTERNAL MEDICINE, 24(3), 565–570.
author keywords: Canine; Cerebellar abiotrophy; Cerebellar ataxia; Polyglucosan body; Purkinje cell
MeSH headings : Animals; Cerebellum / pathology; Dog Diseases / genetics; Dogs; Female; Genetic Predisposition to Disease; Male; Pedigree; Spinocerebellar Degenerations / genetics; Spinocerebellar Degenerations / veterinary
TL;DR:
A hereditary cerebellar degenerative disorder with a relatively mild phenotype has emerged in the Scottish Terrier and genetic analysis results are consistent with an autosomal recessive mode of inheritance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2010 journal article
Overexpression of Transcription Factor Sp2 Inhibits Epidermal Differentiation and Increases Susceptibility to Wound- and Carcinogen-Induced Tumorigenesis
CANCER RESEARCH, 70(21), 8507–8516.
MeSH headings : 9,10-Dimethyl-1,2-benzanthracene / toxicity; Animals; Blotting, Western; COS Cells; Carcinogens / toxicity; Carcinoma, Squamous Cell / etiology; Carcinoma, Squamous Cell / metabolism; Carcinoma, Squamous Cell / pathology; Cattle; Cell Differentiation; Chlorocebus aethiops; Disease Susceptibility; Epidermal Cells; Epidermis / drug effects; Epidermis / metabolism; Female; Humans; Immunoenzyme Techniques; Keratin-5 / genetics; Keratinocytes / cytology; Keratinocytes / drug effects; Keratinocytes / metabolism; Male; Mice; Mice, Transgenic; Promoter Regions, Genetic; RNA, Messenger / genetics; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms / etiology; Skin Neoplasms / metabolism; Skin Neoplasms / pathology; Sp2 Transcription Factor / physiology; Wounds and Injuries
TL;DR:
It is reported that Sp2 protein abundance in mice increases in concert with the progression of carcinogen-induced murine squamous cell carcinomas, and this results directly support the likelihood that Sp2 overexpression occurring in various human cancers has significant functional effect.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2010 journal article
Successful treatment of canine necrolytic migratory erythema (superficial necrolytic dermatitis) due to metastatic glucagonoma with octreotide
VETERINARY DERMATOLOGY, 21(5), 510–516.
Contributors: U. Oberkirchner n, n, L. Zadrozny n & T. Olivry n
MeSH headings : Animals; Anorexia / chemically induced; Anorexia / veterinary; Antineoplastic Agents, Hormonal / administration & dosage; Antineoplastic Agents, Hormonal / adverse effects; Antineoplastic Agents, Hormonal / therapeutic use; Dog Diseases / drug therapy; Dogs; Dose-Response Relationship, Drug; Glucagonoma / complications; Glucagonoma / pathology; Glucagonoma / veterinary; Lymph Nodes / pathology; Male; Necrolytic Migratory Erythema / drug therapy; Necrolytic Migratory Erythema / veterinary; Octreotide / administration & dosage; Octreotide / adverse effects; Octreotide / therapeutic use; Pancreatic Neoplasms / complications; Pancreatic Neoplasms / veterinary; Paraneoplastic Syndromes / pathology; Paraneoplastic Syndromes / veterinary
TL;DR:
Subcutaneous octreotide injections were beneficial in this dog with glucagonoma-associated NME and this somatostatin analogue could be a valuable option to treat canine patients with non-resectable or relapsing pancreatic glucagonomas- associated NME.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2010 article
ULTRASONOGRAPHY OF HISTOLOGICALLY NORMAL PARATHYROID GLANDS AND THYROID LOBULES IN NORMOCALCEMIC DOGS
VETERINARY RADIOLOGY & ULTRASOUND, Vol. 51, pp. 447–452.
author keywords: canine; parathyroid; thyroid; ultrasound
TL;DR:
The purpose of this study is to characterize the sonographic appearance of canine parathyroid glands using high-resolution ultrasonography, with a focus on cadaver dogs studied after euthanasia for reasons not relating to theParathyroid.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Varying phenotypes in swine versus murine transgenic models constitutively expressing the same human Sonic hedgehog transcriptional activator, K5-HGLI2ΔN
Transgenic Research, 19(5), 869–887.
author keywords: Basal cell carcinoma; Pig; Somatic cell nuclear transfer; Gli2; Hedgehog
MeSH headings : Animals; Animals, Genetically Modified / genetics; Animals, Suckling; Epidermis / metabolism; Epidermis / pathology; Female; Fibroblasts / metabolism; Genetic Predisposition to Disease; Hair Follicle / metabolism; Humans; Keratins / metabolism; Kruppel-Like Transcription Factors / genetics; Kruppel-Like Transcription Factors / physiology; Male; Mice; Nuclear Proteins / genetics; Nuclear Proteins / physiology; Phenotype; Pyoderma / etiology; Recombinant Fusion Proteins / physiology; Skin Diseases, Infectious / etiology; Skin Diseases, Infectious / pathology; Species Specificity; Sus scrofa; Swine / metabolism; Transgenes; Zinc Finger Protein Gli2
TL;DR:
There is a need for a multiple species animal model approach in order to better understand the role of Gli2 in mammalian skin, as constitutive expression of the human hGli2ΔN in keratinocytes results in cutaneous changes that have not been reported in the K5-hGli-N murine model.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2009 journal article
ACQUIRED ARTERIOVENOUS FISTULA IN A GRIZZLY BEAR (URSUS ARCTOS HORRIBILIS)
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 40(1), 193–195.
author keywords: Acquired arteriovenous fistula; grizzly bear; Ursus arctos horribilis; trauma; wound
MeSH headings : Animals; Arteriovenous Fistula / diagnosis; Arteriovenous Fistula / surgery; Arteriovenous Fistula / veterinary; Male; Treatment Outcome; Ursidae; Wounds and Injuries / complications; Wounds and Injuries / veterinary
TL;DR:
Arteriovenous fistulas can develop after traumatic injury and should be considered as a potential complication in bears with nonhealing wounds.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Assessment of clotrimazole gels for in vitro stability and in vivo retention in the frontal sinus of dogs
AMERICAN JOURNAL OF VETERINARY RESEARCH, 70(5), 640–647.
MeSH headings : Animals; Antifungal Agents / chemistry; Antifungal Agents / metabolism; Antifungal Agents / pharmacokinetics; Clotrimazole / chemistry; Clotrimazole / metabolism; Clotrimazole / pharmacokinetics; Dogs / metabolism; Drug Stability; Frontal Sinus / diagnostic imaging; Frontal Sinus / metabolism; Gels / chemistry; Gels / metabolism; Male; Poloxamer / chemistry; Poloxamer / metabolism; Tomography, X-Ray Computed / veterinary
TL;DR:
Poloxamer gels had the most promise for improving drug contact within the frontal sinus of dogs, while limiting the inflammatory response.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Canine cutaneous epitheliotropic T-cell lymphoma with vesiculobullous lesions resembling human bullous mycosis fungoides
Veterinary Dermatology, 20(4), 281–288.
Contributors: P. Bizikova*, *, S. Suter*, A. Van Wettere* & T. Olivry*
MeSH headings : Animals; Dog Diseases / pathology; Dogs; Lymphoma, T-Cell / pathology; Lymphoma, T-Cell / veterinary; Male; Skin Neoplasms / pathology; Skin Neoplasms / veterinary
TL;DR:
Clonal rearrangement analysis of antigen receptor genes in samples from skin and lung lesions using primers specific for canine T- cell receptor gamma produced a single-sized amplicon of identical sequence, indicating that both lesions resulted from the expansion of the same neoplastic T-cell population.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2009 journal article
Cross-contamination in the Molecular Detection of Bartonella from Paraffin-embedded Tissues
Veterinary Pathology, 46(5), 940–944.
author keywords: Bartonellosis; cross-contamination; necropsy; paraffin-embedded tissue; PCR contamination
MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Equipment Contamination; Polymerase Chain Reaction / methods
TL;DR:
Unless stringent procedures are established and followed to avoid cross-contamination, the molecular detection of Bartonella spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2009 journal article
Dermatoses affecting desmosomes in animals: a mechanistic review of acantholytic blistering skin diseases
VETERINARY DERMATOLOGY, 20(5-6), 313–326.
Contributors: T. Olivry n & n
MeSH headings : Animals; Cell Adhesion; Dermatomycoses / genetics; Dermatomycoses / pathology; Dermatomycoses / physiopathology; Dermatomycoses / veterinary; Desmosomes / pathology; Epidermolysis Bullosa / genetics; Epidermolysis Bullosa / pathology; Epidermolysis Bullosa / physiopathology; Epidermolysis Bullosa / veterinary; Skin Diseases, Bacterial / genetics; Skin Diseases, Bacterial / pathology; Skin Diseases, Bacterial / physiopathology; Skin Diseases, Bacterial / veterinary
TL;DR:
The similarity of mechanisms explains why clinical and microscopic skin lesions overlap between entities, thus leaving clinicians and dermatopathologists with the conundrum of determining whether the acantholysis is of genetic, autoimmune or infectious origin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2009 journal article
Effects of fascial abrasion, fasciotomy, and fascial excision on cutaneous wound healing in cats
American Journal of Veterinary Research, 70(4), 532–538.
MeSH headings : Animals; Cats / injuries; Cats / physiology; Fasciotomy; Male; Random Allocation; Skin / growth & development; Skin / injuries; Time Factors; Wound Healing
TL;DR:
Fasciotomy and fascial excision facilitated early granulation tissue development in cutaneous wounds in cats and may expedite secondary wound closure or skin grafting in clinical use.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2009 journal article
Isolation of Bartonella vinsonii subsp. berkhoffii Genotype II from a Boy with Epithelioid Hemangioendothelioma and a Dog with Hemangiopericytoma
Journal of Clinical Microbiology, 47(6), 1957–1960.
MeSH headings : Adolescent; Animals; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Dog Diseases / microbiology; Dogs; Female; Genotype; Hemangioendothelioma, Epithelioid / complications; Hemangiopericytoma / complications; Hemangiopericytoma / veterinary; Humans; Male
TL;DR:
Results suggest that B. vinsonii subsp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2009 journal article
Post-traumatic peripheral arteriovenous fistula manifesting as digital haemorrhages in a cat: diagnosis with contrast-enhanced 3D CT imaging
VETERINARY DERMATOLOGY, 20(3), 206–213.
Contributors: D. Santoro n, A. Pease n, n & T. Olivry n
MeSH headings : Animals; Arteriovenous Fistula / diagnosis; Arteriovenous Fistula / etiology; Arteriovenous Fistula / pathology; Arteriovenous Fistula / veterinary; Cat Diseases / diagnosis; Cat Diseases / pathology; Cats; Diagnosis, Differential; Female; Forelimb / pathology; Hypertension / complications; Hypertension / veterinary; Imaging, Three-Dimensional / veterinary; Tomography Scanners, X-Ray Computed / veterinary
TL;DR:
The differential diagnosis for localized, nonhealing, haemorrhagic, crusted, erosive or ulcerative distal extremity skin lesions in cats should include acquired AVF, and diagnosis may be confirmed with contrast-enhanced CT imaging.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2009 journal article
Recurrent Osteomyelitis in a Cat due to Infection with Bartonella vinsonii subsp. berkhoffii Genotype II
Journal of Veterinary Internal Medicine, 23(6), 1273–1277.
MeSH headings : Amoxicillin-Potassium Clavulanate Combination / therapeutic use; Animals; Anti-Bacterial Agents / therapeutic use; Azithromycin / therapeutic use; Bartonella / classification; Bartonella / genetics; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Cat Diseases / drug therapy; Cat Diseases / microbiology; Cats; Female; Osteomyelitis / drug therapy; Osteomyelitis / microbiology; Osteomyelitis / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2009 journal article
Solitary Intracerebral Plasmacytoma in a Dog: Microscopic, Immunohistochemical, and Molecular Features
Veterinary Pathology, 46(5), 949–951.
author keywords: Brain neoplasia; canine; dogs; immunohistochemistry; plasma cell tumor; plasmacytoma; PCR
MeSH headings : Animals; Brain Neoplasms / pathology; Brain Neoplasms / veterinary; Dog Diseases / pathology; Dogs; Fatal Outcome; Female; Histocytochemistry / veterinary; Plasmacytoma / pathology; Plasmacytoma / veterinary; Seizures / pathology; Seizures / veterinary
TL;DR:
Although primary solitary intracerebral plasmacytoma is rare in dogs and other species, it should be included in the differential diagnosis for central nervous system round-cell neoplasms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2009 journal article
‘Putting our heads together’: insights into genomic conservation between human and canine intracranial tumors
Journal of Neuro-Oncology, 94(3), 333–349.
author keywords: Comparative genomic hybridization; Canine; Brain tumor; Chromosome; Microarray
MeSH headings : Animals; Brain Neoplasms / genetics; Brain Neoplasms / pathology; Chromosome Aberrations; Chromosome Mapping; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 22; Cluster Analysis; Dogs; Female; Gene Expression Regulation, Neoplastic; Genome / genetics; Glioma / genetics; Glioma / pathology; Humans; In Situ Hybridization, Fluorescence; Male; Meningeal Neoplasms / genetics; Meningeal Neoplasms / pathology; Meningioma / genetics; Meningioma / pathology
TL;DR:
A microarray-based comparative genomic hybridization analysis of 60 spontaneous canine intracranial tumors was performed to examine the degree to which dog and human patients exhibit aberrations of ancestrally related chromosome regions, consistent with a shared pathogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2008 journal article
Aural Cholesteatoma in Twenty Dogs
VETERINARY SURGERY, 37(8), 763–770.
MeSH headings : Animals; Cholesteatoma, Middle Ear / pathology; Cholesteatoma, Middle Ear / surgery; Cholesteatoma, Middle Ear / veterinary; Dog Diseases / pathology; Dog Diseases / surgery; Dogs; Female; Male; Osteotomy / methods; Osteotomy / veterinary; Postoperative Complications / veterinary; Prognosis; Recurrence; Severity of Illness Index; Treatment Outcome
TL;DR:
Signs and symptoms of aural cholesteatoma may affect the prognosis for successful surgical treatment of middle ear disease and early surgical treatment with curative treatment may be curative.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2008 journal article
MORTALITIES ASSOCIATED WITH SEPSIS, PARASITISM, AND DISSEMINATED ROUND CELL NEOPLASIA IN YELLOW-LIPPED SEA KRAITS (LATICAUDA COLUBRINA)
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 39(4), 626–630.
author keywords: Laticauda colubrina; neoplasia; parasite; sepsis; yellow-tipped sea krait
MeSH headings : Animals; Animals, Zoo; Cause of Death; Elapidae; Neoplasms / mortality; Neoplasms / pathology; Neoplasms / veterinary; Parasitic Diseases, Animal / mortality; Parasitic Diseases, Animal / pathology; Sepsis / mortality; Sepsis / pathology; Sepsis / veterinary; Stress, Psychological; Transportation
TL;DR:
It is presumed that an immunosuppressive event, such as transport, captivity stress, or possible concurrent viral infection, resulted in a septic event and death in yellow-lipped sea kraits at an exhibit aquarium.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2008 journal article
Primary intimal aortic angiosarcoma in a dog
VETERINARY PATHOLOGY, 45(3), 361–364.
author keywords: aneurysm; angiosarcoma; aorta; canines; CD31; immunohistochemistry; thromboembolism
MeSH headings : Animals; Aortic Diseases / pathology; Aortic Diseases / veterinary; Dog Diseases / pathology; Dogs; Euthanasia; Factor VIII / analysis; Female; Hemangiosarcoma / pathology; Hemangiosarcoma / veterinary; Orchiectomy / veterinary; Platelet Endothelial Cell Adhesion Molecule-1 / analysis; Tunica Intima / pathology; Vimentin / analysis
TL;DR:
This is the first description of a primary intimal aortic angiosarcoma in a dog, with immunohistochemical evidence of endothelial origin, in a 4-year-old, spayed female German Shepherd.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Secondary amyloidosis and renal failure in a captive California sea lion (Zalophus californianus)
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 39(2), 274–278.
author keywords: California sea lion; renal failure; secondary amyloidosis; Zalophus californianus
MeSH headings : Amyloidosis / complications; Amyloidosis / diagnosis; Amyloidosis / pathology; Amyloidosis / veterinary; Animals; Animals, Zoo; Fatal Outcome; Female; Immunohistochemistry / veterinary; Renal Insufficiency / diagnosis; Renal Insufficiency / etiology; Renal Insufficiency / pathology; Renal Insufficiency / veterinary; Sea Lions
TL;DR:
Systemic amyloidosis should be considered as an additional differential diagnosis for renal failure in California sea lions after intermittent lethargy, partial anorexia, and polydipsia of 2 wk duration.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2007 journal article
Imaging diagnosis-synchronous primary brain tumors in a dog
VETERINARY RADIOLOGY & ULTRASOUND, 48(6), 550–553.
Contributors: E. MacKillop n, D. Thrall n, R. Ranck n, n & K. Munana n
MeSH headings : Animals; Astrocytoma / pathology; Astrocytoma / veterinary; Cerebellar Neoplasms / pathology; Cerebellar Neoplasms / veterinary; Diagnosis, Differential; Dog Diseases / cerebrospinal fluid; Dog Diseases / pathology; Dogs; Magnetic Resonance Imaging / veterinary; Male; Medulloblastoma / pathology; Medulloblastoma / veterinary; Neoplasms, Multiple Primary / pathology; Neoplasms, Multiple Primary / veterinary; Thalamic Diseases / pathology; Thalamic Diseases / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
4. Quality Education
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 journal article
Intramedullary cavernous malformation of the spinal cord in two dogs
VETERINARY PATHOLOGY, 44(4), 528–532.
author keywords: cavernous hemangioma; hemorrhage; spinal cord; vascular malformation
MeSH headings : Animals; Dog Diseases / pathology; Dogs; Female; Male; Spinal Cord / abnormalities; Spinal Cord / blood supply; Spinal Cord / pathology
TL;DR:
CVMs appear to be an uncommon cause of both acute and chronic spinal cord disease in the dog.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2007 journal article
Malignant peripheral nerve sheath tumor in a hamster
Journal of the American Association for Laboratory Animal Science, 46(6), 55–57.
Source: NC State University Libraries
Added: August 6, 2018
2007 journal article
Pathological fracture of the ulna due to osteosarcoma in an Arabian camel (Camelus dromedarius)
VETERINARY RECORD, 161(1), 30–33.
MeSH headings : Animals; Bone Neoplasms / complications; Bone Neoplasms / diagnosis; Bone Neoplasms / diagnostic imaging; Bone Neoplasms / surgery; Bone Neoplasms / veterinary; Bone Screws / veterinary; Camelus; Diagnosis, Differential; Female; Fracture Fixation, Internal / veterinary; Fracture Healing; Osteosarcoma / complications; Osteosarcoma / diagnosis; Osteosarcoma / diagnostic imaging; Osteosarcoma / surgery; Osteosarcoma / veterinary; Radiography; Ulna Fractures / complications; Ulna Fractures / diagnosis; Ulna Fractures / diagnostic imaging; Ulna Fractures / surgery; Ulna Fractures / veterinary
TL;DR:
This short communication describes a case of pathological fracture secondary to osteosarcoma in an Arabian camel, a seven-year-old intact female Arabian camel presented to the North Carolina State University's College of Veterinary Medicine Veterinary Teaching Hospital for evaluation of a left forelimb lameness of three days’ duration.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Marked swelling with coalescing ecchymoses of the lower mandible in a Xenopus laevis frog
LAB ANIMAL, 35(5), 19–22.
MeSH headings : Animals; Ecchymosis / microbiology; Ecchymosis / pathology; Ecchymosis / veterinary; Fatal Outcome; Female; Mandible / microbiology; Mandible / pathology; Mouth Mucosa / microbiology; Mouth Mucosa / pathology; Mycobacterium Infections / complications; Mycobacterium Infections / pathology; Mycobacterium Infections / veterinary; Mycobacterium marinum / isolation & purification; Oral Ulcer / microbiology; Oral Ulcer / pathology; Oral Ulcer / veterinary; Purpura / microbiology; Purpura / pathology; Purpura / veterinary; Xenopus laevis
TL;DR:
A female African clawed frog, Xenopus laevis, was housed at the Biological Resources Facility of North Carolina State University in a tank with two other females and euthanized in buffered MS-222 so that a complete necropsy could be performed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
What is your diagnosis? Reluctant to dive: coelomic effusion in a frog
VETERINARY CLINICAL PATHOLOGY, 35(3), 341–344.
Contributors: J. Tarigo*, *, J. Neel* , S. Harvey*, A. Remick* & C. Grindem*
author keywords: amphibian; cytology; mycobacteriosis; Xenopus
MeSH headings : Animals; Fatal Outcome; Female; Mycobacterium Infections, Nontuberculous / diagnosis; Mycobacterium Infections, Nontuberculous / pathology; Mycobacterium Infections, Nontuberculous / veterinary; Mycobacterium marinum / isolation & purification; Polymerase Chain Reaction / veterinary; Staining and Labeling / methods; Staining and Labeling / veterinary; Xenopus laevis / microbiology
TL;DR:
Cytologic examination of coelomic effusion fluid at the NCSU veterinary teaching hospital revealed a mixed population of inflammatory cells, including heterophils and a predominance of large mononuclear cells (macrophages) that often contained intracytoplasmic, negatively-stained, rod-shaped to filamentous organisms consistent with Mycobacterium sp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2004 journal article
Effect of four different suture materials on the surgical wound healing of loggerhead sea turtles, Caretta caretta
Journal of Herpetological Medicine and Surgery, 14(4), 6.
TL;DR:
The tissue reaction to four suture materials placed in the skin of juvenile loggerhead sea turtles, Caretta caretta, was evaluated both grossly and histologically.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2004 journal article
Uterine smooth muscle tumors in potbellied pigs (Sus scrofa) resemble human fibroids: A potential animal model
TOXICOLOGIC PATHOLOGY, 32(4), 402–407.
author keywords: uterus; leiomyoma; potbellied pig; fibroids; porcine; animal model
MeSH headings : Animals; Disease Models, Animal; Female; Humans; Immunohistochemistry; Leiomyoma / pathology; Medical Records; Retrospective Studies; Smooth Muscle Tumor / pathology; Smooth Muscle Tumor / veterinary; Sus scrofa; Uterine Neoplasms / pathology; Uterine Neoplasms / veterinary
TL;DR:
The results of this retrospective study support further investigation of uterine leiomyomas in potbellied pigs as a potentially valuable animal model for studying human fibroids.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 chapter
The skin xenograft mouse model in veterinary dermatology research modeling canine demodicosis
In K. Thoday, C. Foil, R. Bond, K. Linder, W. Parker, G. Kunkle, & J. Yager (Eds.), Advances in Veterinary Dermatology (Vol. 4). Boston, MA: Blackwell Science.
Ed(s): K. Thoday, C. Foil, R. Bond, , W. Parker, G. Kunkle, J. Yager
Source: NC State University Libraries
Added: August 13, 2021
2002 journal article
Animal Models for Skin Blistering Conditions: Absence of Laminin 5 Causes Hereditary Junctional Mechanobullous Disease in the Belgian Horse
Journal of Investigative Dermatology, 119(3), 684–691.
author keywords: epitheliogenesis imperfecta; genodermatosis; Lamc2
TL;DR:
The observations suggest that the affected foals are a convenient source of epithelial cells from tissues that cannot be obtained from human junctional epidermolysis bullosa patients, and imply that hairless strains of animals with recessive skin disorders would be the best models for in vivo gene therapy approaches to skin blistering diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: July 21, 2019
2001 journal article
Primer for non-immunologists on immune-deficient mice and their applications in research
Comparative Medicine, 45(4), 300–313.
Source: NC State University Libraries
Added: August 13, 2021
2001 journal article
Skin biopsy site selection in small animal dermatology with an introduction to histologic pattern-analysis of inflammatory skin lesions
CLINICAL TECHNIQUES IN SMALL ANIMAL PRACTICE, 16(4), 207–213.
MeSH headings : Animals; Cat Diseases / pathology; Cats; Dermatitis / pathology; Dermatitis / veterinary; Dog Diseases / pathology; Dogs; Skin Diseases / pathology; Skin Diseases / veterinary; Specimen Handling / veterinary
TL;DR:
To increase the information returned to clinicians for a biopsy, veterinary dermatopathologists have adopted the pattern-analysis method of classifying inflammatory skin lesions, based on recognizing morphologically distinct inflammatory patterns in skin biopsies and their association with particular sets of diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Halicephalobus gingivalis encephalomyelitis in a horse
Canadian Veterinary Journal, 41(7), 559–561.
Source: NC State University Libraries
Added: October 29, 2021
2000 journal article
Sebaceous adenitis in four domestic rabbits (Oryctatagus cuniculus)
Veterinary Dermatology, 11(1), 53–60.
author keywords: rabbit; retinoids; sebaceous adenitis
TL;DR:
Histological changes not consistent with sebaceous adenitis in other species were interface dermatitis and interface folliculitis with single cell necrosis and basal cell hydropic degeneration.
(via Semantic Scholar)
Source: Crossref
Added: July 21, 2019
1998 journal article
Functional anatomy of the cartilage of the distal phalanx and digital cushion in the equine foot and a hemodynamic flow hypothesis of energy dissipation
American Journal of Veterinary Research, 59(8), 961–968.
Source: NC State University Libraries
Added: October 29, 2021
1998 journal article
Halicephalobus gingivalis (Stefanski, 1954) from a fatal infection in a horse in Ontario, Canada with comments on the validity of H. deletrix and a review of the genus
Parasite, 5(3), 255–261.
author keywords: Halicephalobus gingivalis; Micronema; Nematoda; Panagrolaimidae; horse; taxonomy
MeSH headings : Animals; Female; Horse Diseases / parasitology; Horses; Ontario; Parthenogenesis; Rhabditida Infections / parasitology; Rhabditida Infections / veterinary; Rhabditoidea / anatomy & histology; Rhabditoidea / classification; Rhabditoidea / physiology
TL;DR:
It is believed the species reported in horses and humans is H. gingivalis and that H. deletrix is its synonym.
(via Semantic Scholar)
Source: Crossref
Added: April 4, 2021
1997 journal article
Anatomy of the distal interphalangeal joint of the mature horse: relationships with navicular suspensory ligaments, sensory nerves and neurovascular bundle
Equine Veterinary Journal, 29(2), 126–135.
author keywords: horse; sensory nerves; navicular syndrome; sesamoidean impar ligament; distal interphalangeal joint
MeSH headings : Animals; Carpus, Animal / anatomy & histology; Connective Tissue / anatomy & histology; Horses / anatomy & histology; Immunohistochemistry; Joints / anatomy & histology; Ligaments / anatomy & histology; Neurons, Afferent / cytology; Synovial Membrane / anatomy & histology
TL;DR:
Using polymer plastic injections, anatomical observations provide support for the idea that a DIP joint injection of local anaesthetic cannot be considered to be selective for only the joint surfaces, but must be considered also to desensitise much of the navicular suspensory apparatus, navicular bone and proximal intramedullary portions of the distal phalanx.
(via Semantic Scholar)
Source: Crossref
Added: July 21, 2019
1996 journal article
Verteilung eines in das Hufgelenk und in die Bursa podotrochlearis injizierten Lokalanästhetikums: eine experimentelle Studie = Distributions of local anesthetics injected into the distal interphalangeal joint and podotrochlear bursa: an experimental study
Pferdeheilkunde, 12(4), 609–612.
Source: NC State University Libraries
Added: October 29, 2021
1995 journal article
Mammals, other than man, do not have follicular bulges: implications for the bulge-activation hypothesis
Dermatopathology, Practical & Conceptual : Dermatology, Pathology, 1, 155–162.
Source: NC State University Libraries
Added: October 29, 2021
1995 journal article
Sensory innervation of the navicular bone and bursa in the foal
Equine Veterinary Journal, 27(1), 60–65.
author keywords: HORSE; NAVICULAR BURSA; EQUINE ANATOMY; SUBSTANCE P; CALCITONIN GENE-RELATED PEPTIDE
MeSH headings : Animals; Animals, Newborn; Bursa, Synovial / innervation; Horses / anatomy & histology; Immunohistochemistry; Neurons, Afferent / chemistry; Neurons, Afferent / physiology; Neuropeptides / analysis; Sesamoid Bones / innervation
TL;DR:
The sensory innervation of the navicular bone and its suspensory ligaments was examined in the neonatal foal using immunocytochemistry and immunoreactive nerves were demonstrated to innervate the CSL and navicular bursa and SP- and CGRP-like nerves were present in the synovial lining, appearing to reach the surface lining.
(via Semantic Scholar)
Source: Crossref
Added: July 21, 2019
1994 journal article
A silver-impregnation and immunocytochemical study of innervation of the distal sesamoid bone and its suspensory ligaments in the horse
Equine Veterinary Journal, 26(3), 212–219.
author keywords: HORSE; SENSORY NERVES; NAVICULAR SYNDROME; SESAMOIDEAN-IMPAR LIGAMENT; DISTAL INTERPHALANGEAL JOINT
MeSH headings : Animals; Calcitonin Gene-Related Peptide / analysis; Female; Horses / anatomy & histology; Immunohistochemistry / methods; Ligaments, Articular / innervation; Male; Nerve Fibers / chemistry; Nerve Fibers / ultrastructure; Neurokinin A / analysis; Sesamoid Bones / innervation; Silver Staining / veterinary; Substance P / analysis
TL;DR:
The distribution of the nerves in the CSL and the DS-impar ligament could explain the clinical effects of local anaesthetics injected into the distal interphalangeal joint and contribute to the pathology of the navicular syndrome.
(via Semantic Scholar)
Source: Crossref
Added: July 21, 2019
1993 journal article
Sensory receptors in the equine foot
American Journal of Veterinary Research, 54(11), 1840–1844.
Source: NC State University Libraries
Added: October 29, 2021
1992 chapter
Culture Conditions Affect Expression of the α6β4 Integrin Associated with Aggressive Behavior in Head and Neck Cancer
In Advances in Experimental Medicine and Biology (pp. 69–79).
MeSH headings : Antigens, Neoplasm / biosynthesis; Antigens, Surface / biosynthesis; Carcinoma, Squamous Cell / metabolism; Cells, Cultured; Contact Inhibition; Gene Expression Regulation, Neoplastic; Humans; Integrin alpha6beta4; Integrins / biosynthesis; Keratinocytes / metabolism; Keratinocytes / pathology; Laryngeal Neoplasms / metabolism; Melanoma / metabolism; Mouth Neoplasms / metabolism; Skin Neoplasms / metabolism; Tumor Cells, Cultured
TL;DR:
The authors can now examine growth-regulatory mechanisms at the cellular and molecular levels, and they can begin to apply what they learn in new clinical and experimental systems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: July 21, 2019
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