@article{rowe_winston_parker_mccool_suchodolski_lopes_steiner_gilor_rudinsky_2024, title={Gut microbiota promoting propionic acid production accompanies caloric restriction-induced intentional weight loss in cats}, volume={14}, ISSN={["2045-2322"]}, DOI={10.1038/s41598-024-62243-4}, abstractNote={Abstract Rodent models and human clinical studies have shown gut microbiota-derived short-chain fatty acids (SCFAs) play roles in obesity and insulin resistance. These roles have been minimally explored in cats, where in the USA an estimated 60% of cats are overweight or obese. Overweight/obese research cats (n = 7) were transitioned from a maintenance diet to a reduced calorie diet fed ad libitum for 7 days, then calories were restricted to achieve 1–2% weight loss per week for an additional 77 days. Cats then received their original maintenance diet again for 14 days. Significant intentional weight loss was noted after calorie restriction (adjusted p < 0.0001). 16S rRNA gene amplicon sequencing and targeted SCFA metabolomics were performed on fecal samples. Fecal microbial community structure significantly differed between the four study phases (PERMANOVA p = 0.011). Fecal propionic acid was significantly higher during caloric restriction-induced weight loss (adjusted p < 0.05). Repeated measures correlation revealed the relative abundances of Prevotella 9 copri (correlation coefficient = 0.532, 95% CI (0.275, 0.717), p = 0.0002) significantly correlated with propionic acid composition. Like humans, obese cats experienced an altered microbial community structure and function, favoring propionic acid production, during caloric restriction-induced weight loss.}, number={1}, journal={SCIENTIFIC REPORTS}, author={Rowe, J. C. and Winston, J. A. and Parker, V. J. and McCool, K. E. and Suchodolski, J. S. and Lopes, R. and Steiner, J. M. and Gilor, C. and Rudinsky, A. J.}, year={2024}, month={May} } @article{lyon_hofmeister_mccool_shaver_diehl_woolcock_2023, title={Examination of Motivational Influences on Clinical-Year Veterinary Students' Career Decisions}, volume={50}, ISSN={["1943-7218"]}, DOI={10.3138/jvme-2022-0090}, abstractNote={ The purpose of this study was to identify motivations for fourth-year veterinary students to choose future career paths based on post-graduation employment or post-graduation education. Approximately 500 students from four institutions were invited to participate in an online survey. Surveys were based on the cognitive evaluation theory, a minitheory within the self-determination macrotheory framework developed by Deci and Ryan. Intrinsic motivational factors were categorized by autonomy, competence, and relatedness, and extrinsic motivators were categorized by environmental and interpersonal factors. Students pursuing post-graduation education have intrinsic motivators that aligned with competence and were extrinsically motivated by a mentor, while students interested in post-graduation employment had intrinsic motivators that were more focused on autonomy with extrinsic motivational influences of debt/finances and geographic location. }, number={6}, journal={JOURNAL OF VETERINARY MEDICAL EDUCATION}, author={Lyon, Shane D. and Hofmeister, Erik H. and McCool, Katie E. and Shaver, Stephanie L. and Diehl, Kathryn A. and Woolcock, Andrew D.}, year={2023}, month={Dec}, pages={694–702} }