Works (75)

Updated: May 29th, 2024 05:01

2024 article

ACVIM consensus statement on the diagnosis of immune thrombocytopenia in dogs and cats

LeVine, D. N., Kidd, L., Garden, O. A., Brooks, M. B., Goggs, R., Kohn, B., … Spada, E. (2024, May 16). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: D. LeVine, L. Kidd, O. Garden, M. Brooks, R. Goggs, B. Kohn, A. Mackin, E. Eldermire ...

author keywords: autoimmune; hemostasis; immune-mediated; platelet; thrombopoietin
Source: Web Of Science
Added: May 28, 2024

2023 journal article

Assessment of peritubular capillary rarefaction in kidneys of cats with chronic kidney disease

Journal of Veterinary Internal Medicine.

By: R. Paschall*, J. Quimby*, R. Cianciolo*, S. McLeland*, K. Lunn* & J. Elliott*

MeSH headings : Humans; Cats; Animals; Microvascular Rarefaction / complications; Microvascular Rarefaction / pathology; Microvascular Rarefaction / veterinary; Cross-Sectional Studies; Creatinine; Kidney / pathology; Renal Insufficiency, Chronic / complications; Renal Insufficiency, Chronic / veterinary; Fibrosis; Inflammation / pathology; Inflammation / veterinary; Cat Diseases / pathology
TL;DR: Capillary rarefaction (decrease in capillary size and percent capillary area) is present in kidneys of cats with CKD and is positively correlated with renal dysfunction and histopathologic lesions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: February 19, 2023

2023 article

Hemostatic profiles in dogs with sudden acquired retinal degeneration syndrome

Lynch, A. M. M., Ruterbories, L. K. K., Robertson, J. B. B., Lunn, K. F. F., & Mowat, F. M. M. (2023, April 19). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 4.

By: A. Lynch n, L. Ruterbories n, J. Robertson n, K. Lunn n & F. Mowat n

author keywords: coagulation; fibrinogen; hypercoagulability; SARDS
MeSH headings : Dogs; Animals; Retinal Degeneration / veterinary; Case-Control Studies; Hemostatics; Pilot Projects; Thrombophilia / complications; Thrombophilia / veterinary; Fibrinogen; Antithrombins; Thrombelastography / veterinary; Dog Diseases
TL;DR: Hypercoagulability was common in both dogs with SARDS and controls, but dogs with ARDS were significantly more hypercoagULable on TEG, which remains to be determined. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: April 20, 2023

2023 article

Refrigerated multi-dose insulin vials remain sterile through 6 months of use

Berg, A. S., Jacob, M. E., Mamo, L. B., Pluta, D. H., & Lunn, K. F. (2023, August 9). JOURNAL OF SMALL ANIMAL PRACTICE, Vol. 8.

By: A. Berg n, M. Jacob n, L. Mamo n, D. Pluta n & K. Lunn n

TL;DR: Refrigerated phenol- and metacresol-containing multi-dose insulin products carry minimal risk for iatrogenic infection through 6 months of use, regardless of alcohol swab preparation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 11, 2023

2022 journal article

Frequency of histologic lesions in the kidneys of cats without kidney disease

JOURNAL OF FELINE MEDICINE AND SURGERY, 24(12), E472–E480.

By: J. Quimby*, S. McLeland*, R. Cianciolo*, K. Lunn n, J. Lulich*, A. Erikson, L. Barron*

author keywords: Fibrosis; glomerulosclerosis; lipid; chronic kidney disease; tubulointerstitial nephritis
MeSH headings : Humans; Cats; Animals; Cross-Sectional Studies; Kidney Diseases / epidemiology; Kidney Diseases / veterinary; Kidney; Fibrosis; Atrophy / veterinary; Lipids; Cat Diseases / epidemiology
TL;DR: Evidence of renal aging exists in cats and changes imply that the aging kidney may be more susceptible to injury and impaired healing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: January 23, 2023

2022 article

Outcomes of esophageal and gastric bone foreign bodies in dogs

Barash, N. R., Lashnits, E., Kern, Z. T., Tolbert, M. K., & Lunn, K. F. (2022, February 14). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 2.

By: N. Barash n, E. Lashnits n, Z. Kern n, M. Tolbert n & K. Lunn n

author keywords: endoscopy; erosion; esophagus; stomach
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dog Diseases / surgery; Dogs; Endoscopy / veterinary; Esophageal Diseases / veterinary; Foreign Bodies / complications; Foreign Bodies / surgery; Foreign Bodies / veterinary; Retrospective Studies; Stomach
TL;DR: While all E‐bFBs were dislodged either by advancement into the stomach, endoscopic removal, or esophagotomy, the majority of gastric bone foreign bodies were left in situ for dissolution, with no reported complications. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 15, 2022

2021 journal article

Neutropenia in dogs receiving vincristine for treatment of presumptive immune-mediated thrombocytopenia

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(1), 226–233.

By: K. LaQuaglia n, J. Robertson n & K. Lunn n

author keywords: cyclosporine; myelosuppression; neutrophil; platelet
MeSH headings : Animals; Dog Diseases / drug therapy; Dogs; Neutropenia / chemically induced; Neutropenia / drug therapy; Neutropenia / veterinary; Retrospective Studies; Thrombocytopenia / chemically induced; Thrombocytopenia / veterinary; Vincristine / adverse effects
TL;DR: Cyclosporine administration was associated with the development of neutropenia in dogs receiving vincristine, which might be related to effects on metabolism of vINCristine. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 15, 2021

2021 journal article

Renal Senescence, Telomere Shortening and Nitrosative Stress in Feline Chronic Kidney Disease

VETERINARY SCIENCES, 8(12).

By: J. Quimby*, A. Erickson*, S. Mcleland*, R. Cianciolo*, D. Maranon*, K. Lunn n, J. Elliott*, J. Lawson* ...

author keywords: feline; cat; renal disease; senescence; aging
TL;DR: Increased renal senescence, telomere shortening, and nitrosative stress in feline CKD is demonstrated, identifying these patients as potential candidates for senolytic therapy with translational potential. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 10, 2022

2021 article

Simultaneous primary hyperparathyroidism and multiple myeloma in a dog with hypercalcaemia

Sztukowski, K., Gin, T., Neel, J., & Lunn, K. (2021, October 5). VETERINARY RECORD CASE REPORTS, Vol. 10.

By: K. Sztukowski n, T. Gin n, J. Neel n & K. Lunn n

Contributors: K. Sztukowski n, T. Gin n, J. Neel n & K. Lunn n

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 18, 2021

2020 other

Leptospirosis

By: K. Lunn n

Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2020 journal article

Perceptions and attitudes of Small Animal Internal Medicine specialists toward the publication requirement for board certification

JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(2), 574–580.

By: A. Birkenheuer n, K. Royal n, A. Cerreta n, D. Hemstreet n, K. Lunn n, J. Gookin n, S. McGarvey n

author keywords: board certification; credentials; education; residency training
MeSH headings : Authorship; Certification; Humans; Societies, Scientific / organization & administration; Societies, Scientific / standards; Specialization; Specialty Boards / standards; Veterinary Medicine / organization & administration; Veterinary Medicine / standards
TL;DR: A majority of SAIM Diplomates favored the retention of the publication requirement in some form, and publications submitted for credentialing purposes were cited at rates similar to control articles. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 17, 2020

2020 chapter

Tumors of the Endocrine System

In D. M. Vail, D. H. Thamm, & J. M. Liptak (Eds.), Withrow and MacEwen's Small Animal Clinical Oncology (6th edition, pp. 565–596).

By: K. Lunn* & S. Boston

Ed(s): D. Vail, D. Thamm & J. Liptak

Sources: Crossref, NC State University Libraries
Added: October 23, 2020

2019 journal article

Circulating neurohormone imbalances in canine sudden acquired retinal degeneration syndrome and canine pituitary-dependent hypercortisolism

JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(6), 2587–2594.

By: A. Oh n, M. Foster n, K. Lunn n & F. Mowat n

author keywords: dog; dopamine; melatonin; PDH; retina; SARDS; serotonin
MeSH headings : Animals; Case-Control Studies; Dog Diseases / blood; Dog Diseases / metabolism; Dogs; Dopamine / blood; Melatonin / analogs & derivatives; Melatonin / blood; Melatonin / urine; Pituitary ACTH Hypersecretion / blood; Pituitary ACTH Hypersecretion / metabolism; Pituitary ACTH Hypersecretion / veterinary; Prospective Studies; Retinal Degeneration / blood; Retinal Degeneration / metabolism; Retinal Degeneration / veterinary; Serotonin / blood
TL;DR: This study has identified neurohormone differences between dogs with SARDS and PDH, although the study was underpowered for detection of significant differences in serum serotonin. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: November 11, 2019

2019 journal article

Diagnostic utility of clinical and laboratory test parameters for differentiating between sudden acquired retinal degeneration syndrome and pituitary‐dependent hyperadrenocorticism in dogs

Veterinary Ophthalmology, 22(6), 842–858.

By: A. Oh n, M. Foster n, J. Williams n, C. Zheng n, H. Ru n, K. Lunn n, F. Mowat n

author keywords: biomarker; dog; hyperadrenocorticism; retina; sudden acquired retinal degeneration syndrome
MeSH headings : Animals; Case-Control Studies; Dog Diseases / diagnosis; Dogs; Electroretinography / veterinary; Female; Male; Pituitary ACTH Hypersecretion / diagnosis; Pituitary ACTH Hypersecretion / veterinary; Retina / pathology; Retinal Degeneration / diagnosis; Retinal Degeneration / veterinary; Tomography, Optical Coherence / veterinary
TL;DR: This work provides the basis for future studies that could identify and examine dogs with SARDS prior to vision loss, which may extend the potential therapeutic window for SARDS. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: December 16, 2019

2019 journal article

Investigation of adrenal and thyroid gland dysfunction in dogs with ultrasonographic diagnosis of gallbladder mucocele formation

PLOS ONE, 14(2), e0212638.

By: K. Aicher n, J. Cullen n, G. Seiler n, K. Lunn n, K. Mathews n & J. Gookin n

Ed(s): J. Loor

MeSH headings : Adrenal Glands / physiopathology; Adrenocortical Hyperfunction / epidemiology; Adrenocortical Hyperfunction / physiopathology; Adrenocortical Hyperfunction / veterinary; Animals; Autoantibodies / blood; Case-Control Studies; Dehydroepiandrosterone / blood; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / physiopathology; Dogs; Electronic Health Records; Female; Gallbladder / diagnostic imaging; Gallbladder Diseases / blood; Gallbladder Diseases / physiopathology; Gallbladder Diseases / veterinary; Hypothyroidism / epidemiology; Hypothyroidism / physiopathology; Hypothyroidism / veterinary; Male; Mucocele / blood; Mucocele / physiopathology; Mucocele / veterinary; Prevalence; Retrospective Studies; Thyroid Gland / physiopathology; Ultrasonography
TL;DR: It is suggested that dogs with gallbladder mucocele formation have a greater capacity for cortisol synthesis and pinpoint DHEAS elevations as a potential clue to the underlying pathogenesis of the disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: November 11, 2019

2018 journal article

Clinical therapeutic efficacy of mycophenolate mofetil in the treatment of SARDS in dogs-a prospective open-label pilot study

VETERINARY OPHTHALMOLOGY, 21(6), 565–576.

By: W. Young n, A. Oh n, J. Williams n, M. Foster n, W. Miller*, K. Lunn n, F. Mowat n

author keywords: dog; mycophenolate mofetil; retina; sudden acquired retinal degeneration syndrome; treatment; vision
MeSH headings : Animals; Dog Diseases / drug therapy; Dogs; Female; Immunosuppressive Agents / therapeutic use; Male; Mycophenolic Acid / therapeutic use; Pilot Projects; Prospective Studies; Retinal Degeneration / drug therapy; Retinal Degeneration / veterinary; Vision Tests / veterinary
TL;DR: The effect of sole-agent treatment with mycophenolate mofetil as a sole agent has no measureable positive effect on physical health, vision, or retinal structure following a 6-week trial period. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 3, 2018

2018 journal article

Stereotactic radiation therapy for the treatment of functional pituitary adenomas associated with feline acromegaly

Journal of Veterinary Internal Medicine, 32(4), 1383–1391.

By: T. Wormhoudt*, M. Boss*, K. Lunn n, L. Griffin*, D. Leary*, K. Dowers*, S. Rao*, S. LaRue*

author keywords: cats; hypofractionated radiation therapy; megavoltage radiation; SRT
MeSH headings : Adenoma / diagnostic imaging; Adenoma / mortality; Adenoma / radiotherapy; Adenoma / veterinary; Animals; Cat Diseases / diagnostic imaging; Cat Diseases / mortality; Cat Diseases / radiotherapy; Cats; Female; Growth Hormone-Secreting Pituitary Adenoma / diagnostic imaging; Growth Hormone-Secreting Pituitary Adenoma / mortality; Growth Hormone-Secreting Pituitary Adenoma / radiotherapy; Growth Hormone-Secreting Pituitary Adenoma / veterinary; Male; Radiosurgery / mortality; Radiosurgery / veterinary; Retrospective Studies; Survival Analysis; Tomography, X-Ray Computed / veterinary; Treatment Outcome
TL;DR: Stereotactic radiation therapy is safe and effective for treating cats with acromegaly and Cats treated with SRT have improved survival time and control of their DM when compared to previously reported patients treated with non‐SRT. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: October 23, 2020

2016 conference paper

Coalescence prevention algorithm for level set method

Proceedings of the asme fluids engineering division summer meeting, 2016, vol 1b.

By: M. Talley n, M. Zimmer n & I. Bolotnov n

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2016 journal article

Evaluation of the genetic basis of primary hypoadrenocorticism in Standard Poodles using SNP array genotyping and whole-genome sequencing

Mammalian Genome, 28(1-2), 56–65.

By: S. Friedenberg n, K. Lunn n & K. Meurs n

MeSH headings : Addison Disease / genetics; Addison Disease / pathology; Animals; Dog Diseases / genetics; Dogs; Genome-Wide Association Study; Genotyping Techniques; Humans; Hypoadrenocorticism, Familial / genetics; Hypoadrenocorticism, Familial / pathology; Polymorphism, Single Nucleotide; Whole Genome Sequencing / methods
TL;DR: A genome-wide association study of 133 carefully phenotyped Standard Poodles found no markers significantly associated with primary hypoadrenocorticism and identified several candidate genes that may be fixed in both Standard POODles and a small population of dogs of related breeds. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2016 chapter

Fever of Unknown Origin

In S. E. Aiello, M. A. Moses, & D. G. Allen (Eds.), The Merck Veterinary Manual (11th Edition, pp. 1015–1017). Kenilworth, NJ: Merck & Co., Inc.

By: K. Lunn

Ed(s): S. Aiello, M. Moses & D. Allen

Source: NC State University Libraries
Added: March 17, 2021

2016 chapter

Leptospirosis

In S. E. Aiello & M. A. Moses (Eds.), The Merck Veterinary Manual (11th Edition, pp. 646–653). Kenilworth, NJ: Merck & Co., Inc.

By: K. Lunn

Ed(s): S. Aiello & M. Moses

Source: NC State University Libraries
Added: March 5, 2021

2015 journal article

Abdominal ultrasonographic findings in acromegalic cats

JOURNAL OF FELINE MEDICINE AND SURGERY, 17(8), 698–703.

By: B. Lourenco n, E. Randall*, G. Seiler n & K. Lunn n

MeSH headings : Acromegaly / pathology; Acromegaly / veterinary; Animals; Case-Control Studies; Cat Diseases / blood; Cat Diseases / diagnostic imaging; Cat Diseases / pathology; Cats; Female; Insulin-Like Growth Factor I / metabolism; Male; Reference Values; Retrospective Studies; Statistics, Nonparametric; Ultrasonography
TL;DR: Findings indicate that compared with non-acromegalic cats, age-matched acromegaly patients have measurably larger kidneys, adrenal glands and pancreas than poorly regulated diabetic cats exhibiting organomegaly on abdominal ultrasound examination. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Opinions of clinical veterinarians at a US veterinary teaching hospital regarding antimicrobial use and antimicrobial-resistant infections

Journal of the American Veterinary Medical Association, 247(8), 938–944.

By: M. Jacob*, J. Hoppin*, N. Steers*, J. Davis*, G. Davidson*, B. Hansen, K. Lunn*, K. Murphy, M. Papich*

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteria / drug effects; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Cross-Sectional Studies; Data Collection; Drug Resistance, Bacterial; Education, Veterinary; Female; Hospitals, Animal; Humans; Male; Professional Practice; Schools, Veterinary; United States; Veterinarians
TL;DR: Findings indicated that veterinarians at this teaching hospital were concerned about antimicrobial resistance, thought antimicrobials were overprescribed, and supported restricting use of certain antimicrobial classes in companion animals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Echocardiographic Findings in 11 Cats with Acromegaly

JOURNAL OF VETERINARY INTERNAL MEDICINE, 28(4), 1235–1238.

By: J. Myers*, K. Lunn n & J. Bright*

author keywords: Acromegaly; Cardiomyopathy; Endocrinopathy; Feline
MeSH headings : Acromegaly / complications; Acromegaly / diagnostic imaging; Acromegaly / veterinary; Animals; Cat Diseases / diagnostic imaging; Cats; Echocardiography / veterinary; Female; Heart Atria / diagnostic imaging; Heart Diseases / diagnostic imaging; Heart Diseases / etiology; Heart Diseases / veterinary; Hypertrophy, Left Ventricular / diagnostic imaging; Hypertrophy, Left Ventricular / veterinary; Male; Retrospective Studies
TL;DR: Cardiovascular abnormalities frequently are present in cats with acromegaly, and a complete cardiac evaluation should be considered in these patients. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 chapter

Leptospirosis

In J. D. Bonagura & D. C. Twedt (Eds.), Kirk’s Current Veterinary Therapy (15th edition, pp. 1286–1289). St. Louis, MO: Elsevier Saunders.

By: K. Lunn

Ed(s): J. Bonagura & D. Twedt

Source: NC State University Libraries
Added: March 17, 2021

2014 journal article

Relationship among Serum Creatinine, Serum Gastrin, Calcium-phosphorus Product, and Uremic Gastropathy in Cats with Chronic Kidney Disease

Journal of Veterinary Internal Medicine, 28(3), 827–837.

By: S. McLeland*, K. Lunn*, C. Duncan*, K. Refsal* & J. Quimby*

author keywords: Chronic renal failure; Feline; Gastritis; Stomach
MeSH headings : Animals; Calcium / blood; Cat Diseases / blood; Cat Diseases / pathology; Cats / blood; Creatinine / blood; Female; Fibrosis; Gastrins / blood; Male; Phosphorus / blood; Renal Insufficiency, Chronic / blood; Renal Insufficiency, Chronic / complications; Renal Insufficiency, Chronic / pathology; Renal Insufficiency, Chronic / veterinary; Stomach / pathology; Uremia / complications; Uremia / pathology; Uremia / veterinary
TL;DR: Uremic gastropathy in CKD cats differs from that described in other species and this difference should be considered when devising medical management. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2013 journal article

Accuracy of CT and MRI for contouring the feline optic apparatus for radiation therapy planning

Veterinary Radiology & Ultrasound, 54(5), 560–566.

By: M. Nolan*, E. Randall*, S. LaRue*, K. Lunn n, J. Stewart* & S. Kraft*

author keywords: acromegaly; brain tumors; optic chiasm; optic pathway; stereotactic radiation therapy; radiosurgery
MeSH headings : Acromegaly / diagnosis; Acromegaly / etiology; Acromegaly / pathology; Acromegaly / veterinary; Animals; Cadaver; Cat Diseases / diagnosis; Cat Diseases / etiology; Cat Diseases / pathology; Cats / anatomy & histology; Magnetic Resonance Imaging / methods; Magnetic Resonance Imaging / standards; Magnetic Resonance Imaging / veterinary; Optic Chiasm / anatomy & histology; Optic Chiasm / diagnostic imaging; Optic Chiasm / pathology; Optic Nerve / anatomy & histology; Optic Nerve / diagnostic imaging; Optic Nerve / pathology; Prospective Studies; Reference Values; Tomography, X-Ray Computed / methods; Tomography, X-Ray Computed / standards; Tomography, X-Ray Computed / veterinary
TL;DR: Findings from the current study supported the use of a combination of CT and MR images and a priori knowledge of the shape of the optic apparatus to guide accurate contouring, especially where image contrast is not sufficient to clearly delineate the margins. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Comparison of the Infectivity and Transmission of Contemporary Canine and Equine H3N8 Influenza Viruses in Dogs

Veterinary Medicine International, 2013, 1–10.

By: H. Pecoraro*, S. Bennett*, K. Garretson*, A. Quintana*, K. Lunn* & G. Landolt*

TL;DR: The results of the in vivo experiments reported here suggesting that dogs are susceptible to EIV and previous reports by members of the authors' laboratory showing limited CIV infection in horses have been mirrored in CIV and EIV infections studies in primary canine and equine respiratory epithelial cells. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2013 chapter

Diabetes Insipidus and Polyuria/Polydipsia in Dogs

In J. Rand (Ed.), Clinical Endocrinology of Companion Animals (pp. 436–449).

By: K. Lunn* & K. James

Ed(s): J. Rand

Sources: NC State University Libraries, NC State University Libraries
Added: March 17, 2021

2013 journal article

Equine Viral Respiratory Pathogen Surveillance at Horse Shows and Sales

Journal of Equine Veterinary Science, 33(4), 229–237.

By: J. Carlson*, J. Traub-Dargatz*, D. Lunn*, P. Morley*, A. Kohler*, K. Kasper*, G. Landolt*, D. Barnett, K. Lunn*

author keywords: Horse respiratory viruses; Equine herpesvirus-1; Equine herpesvirus-4; Equine influenza virus
TL;DR: Horses younger than 2 years had a significantly greater risk of shedding EHV-1 compared with older horses; no other significant risk factors associated with viral shedding were identified, and there is a risk of exposure to EIV, EHv-1, and EHVs at equine events, and horses and events should be managed to mitigate this risk. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2013 journal article

Evaluation of virus isolation, one-step real-time reverse transcription polymerase chain reaction assay, and two rapid influenza diagnostic tests for detecting canine Influenza A virus H3N8 shedding in dogs

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 25(3), 402–406.

By: H. Pecoraro n, M. Spindel n, S. Bennett n, K. Lunn n & G. Landolt n

author keywords: Canine infectious respiratory disease complex; dogs; Influenza A virus; rapid influenza diagnostic test; real-time reverse transcription polymerase chain reaction; virus isolation
MeSH headings : Animals; Dog Diseases / diagnosis; Dog Diseases / virology; Dogs; Influenza A Virus, H3N8 Subtype / isolation & purification; Orthomyxoviridae Infections / diagnosis; Orthomyxoviridae Infections / veterinary; Orthomyxoviridae Infections / virology; Reverse Transcriptase Polymerase Chain Reaction / veterinary; Sensitivity and Specificity
TL;DR: The real-time RT-PCR has the highest sensitivity for detecting virus nasal shedding and can be used as a rapid diagnostic test for CIV. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Mirtazapine as an appetite stimulant and anti-emetic in cats with chronic kidney disease: A masked placebo-controlled crossover clinical trial

The Veterinary Journal, 197(3), 651–655.

By: J. Quimby* & K. Lunn n

author keywords: Feline; Nutrition; Kidney; Pharmacokinetics; Vomiting
MeSH headings : Animals; Anorexia / drug therapy; Anorexia / veterinary; Antiemetics / therapeutic use; Appetite Stimulants / therapeutic use; Cat Diseases / drug therapy; Cats; Cross-Over Studies; Female; Male; Mianserin / analogs & derivatives; Mianserin / therapeutic use; Mirtazapine; Renal Insufficiency, Chronic / complications; Renal Insufficiency, Chronic / veterinary; Vomiting / drug therapy; Vomiting / veterinary
TL;DR: Mirtazapine is an effective appetite stimulant and anti-emetic for cats with CKD and could be a useful adjunct to the nutritional management of these cases. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 21, 2020

2013 chapter

Tumors of the Endocrine System

In Withrow and MacEwen's Small Animal Clinical Oncology (pp. 504–531).

By: K. Lunn* & R. Page

Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2012 chapter

Fever

In C. E. Greene (Ed.), Infectious Diseases of the Dog and Cat (4th Edition, pp. 1115–1123). St. Louis, MO: Elsevier.

By: K. Lunn

Ed(s): C. Greene

Source: NC State University Libraries
Added: March 17, 2021

2012 chapter

Fluid Therapy

In The Cat (pp. 52–89).

By: K. Lunn*, A. Johnson & K. James

Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2011 journal article

Evaluation of the Effects of Hospital Visit Stress on Physiologic Parameters in the Cat

Journal of Feline Medicine and Surgery, 13(10), 733–737.

By: J. Quimby*, M. Smith* & K. Lunn*

MeSH headings : Animals; Behavior, Animal; Blood Pressure; Cat Diseases / physiopathology; Cats; Female; Heart Rate; Male; Monitoring, Physiologic / veterinary; Office Visits; Respiratory Rate; Stress, Physiological
TL;DR: Comparing physiologic parameter data gathered from cats in the home environment with those gathered in a veterinary hospital environments may help practitioners recognize that physiologic abnormalities can sometimes be due to transportation or environmental stress rather than medical illness. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020

2011 journal article

Raw Food Diets in Dogs: Concerns for Canine and Human Health

Advances in Small Animal Medicine and Surgery, 24(2), 1–2.

By: K. Lunn*

TL;DR: Pet owners should be aware of the potential health implications of feeding raw diets to pet dogs and the risk of carriage of Salmonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020

2011 journal article

Serum fructosamine in cats receiving an oral chondroprotective agent

International Journal of Applied Research in Veterinary Medicine, 9(1), 52–57.

By: K. Davis & K. Lunn

Source: NC State University Libraries
Added: March 17, 2021

2011 journal article

Studies on the pharmacokinetics and pharmacodynamics of mirtazapine in healthy young cats

Journal of Veterinary Pharmacology and Therapeutics, 34(4), 388–396.

By: J. Quimby*, D. Gustafson*, B. Samber & K. Lunn*

MeSH headings : Adrenergic alpha-Antagonists / blood; Adrenergic alpha-Antagonists / pharmacokinetics; Adrenergic alpha-Antagonists / pharmacology; Animals; Appetite / drug effects; Appetite Stimulants / blood; Appetite Stimulants / pharmacokinetics; Appetite Stimulants / pharmacology; Cats / metabolism; Chromatography, Liquid / veterinary; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule / veterinary; Feeding Behavior / drug effects; Female; Male; Mianserin / analogs & derivatives; Mianserin / blood; Mianserin / pharmacokinetics; Mianserin / pharmacology; Mirtazapine; Random Allocation; Tandem Mass Spectrometry / veterinary
TL;DR: Limited serum sampling during the pharmacodynamic study revealed drug exposure comparable with the pharmacokinetic study, but no correlation between exposure and food consumed, and mirtazapine does not appear to display linear pharmacokinetics in cats. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: October 23, 2020

2011 journal article

The Kidney in Critically Ill Small Animals

Veterinary Clinics of North America: Small Animal Practice, 41(4), 727–744.

By: K. Lunn*

author keywords: Kidney; Azotemia; Uremia; Acute renal failure; Acute kidney injury
MeSH headings : Acute Kidney Injury / drug therapy; Acute Kidney Injury / etiology; Acute Kidney Injury / physiopathology; Acute Kidney Injury / veterinary; Animals; Azotemia / drug therapy; Azotemia / etiology; Azotemia / physiopathology; Azotemia / veterinary; Cat Diseases / drug therapy; Cat Diseases / etiology; Cat Diseases / physiopathology; Cats; Creatinine / blood; Critical Illness / epidemiology; Critical Illness / therapy; Dog Diseases / drug therapy; Dog Diseases / etiology; Dog Diseases / physiopathology; Dogs; Humans; Kidney / physiology; Kidney / physiopathology; Kidney Diseases / drug therapy; Kidney Diseases / etiology; Kidney Diseases / physiopathology; Kidney Diseases / veterinary; Reference Values; Risk Factors; Species Specificity; Uremia / drug therapy; Uremia / etiology; Uremia / physiopathology; Uremia / veterinary; Urinalysis / veterinary; Urine / chemistry; Urine / physiology
TL;DR: Measurement of serum creatinine is insensitive for the detection of acute kidney injury, and clinicians should consider assessment of other parameters such as urine output, urinalysis, and urine chemistry results. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020

2011 journal article

The Pharmacokinetics of Mirtazapine in Cats with Chronic Kidney Disease and In Age-Matched Control Cats

Journal of Veterinary Internal Medicine, 25(5), 985–989.

By: J. Quimby*, D. Gustafson* & K. Lunn*

author keywords: Appetite; Feline; Nutrition; Renal
MeSH headings : Animals; Appetite Stimulants / blood; Appetite Stimulants / pharmacokinetics; Appetite Stimulants / therapeutic use; Cat Diseases / drug therapy; Cat Diseases / metabolism; Cats; Creatinine / blood; Female; Half-Life; Kidney Failure, Chronic / drug therapy; Kidney Failure, Chronic / metabolism; Kidney Failure, Chronic / veterinary; Male; Mianserin / analogs & derivatives; Mianserin / blood; Mianserin / pharmacokinetics; Mianserin / therapeutic use; Mirtazapine
TL;DR: A single low dose of mirtazapine resulted in a half-life compatible with a 48-hour dosing interval in CKD cats, suggesting that chronic kidney disease may delay the clearance/bioavailability (CL/F) of mIRTZapine. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2011 journal article

Variability in Results of the Microscopic Agglutination Test in Dogs with Clinical Leptospirosis and Dogs Vaccinated against Leptospirosis

Journal of Veterinary Internal Medicine, 25(3), 426–432.

By: M. Miller*, K. Annis*, M. Lappin* & K. Lunn*

author keywords: Antibody; Diagnosis; Laboratory; Serology
MeSH headings : Agglutination Tests / methods; Agglutination Tests / standards; Agglutination Tests / veterinary; Animals; Antibodies, Bacterial / blood; Bacterial Vaccines / immunology; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / prevention & control; Dogs; Leptospira / immunology; Leptospirosis / blood; Leptospirosis / diagnosis; Leptospirosis / prevention & control; Leptospirosis / veterinary; Reproducibility of Results; Specific Pathogen-Free Organisms
TL;DR: The MAT is a valuable test for the diagnosis of leptospirosis in dogs, but it is unlikely that test results can be used to predict the infecting serogroup, so Laboratories offering the MAT should consider participation in a proficiency scheme. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2010 journal article

2010 ACVIM Small Animal Consensus Statement on Leptospirosis: Diagnosis, Epidemiology, Treatment, and Prevention

Journal of Veterinary Internal Medicine, 25(1), 1–13.

By: J. Sykes*, K. Hartmann*, K. Lunn*, G. Moore*, R. Stoddard* & R. Goldstein*

author keywords: Hepatitis; Leptospira interrogans; Nephritis; Zoonosis
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Antibodies, Bacterial / blood; Bacterial Vaccines / therapeutic use; Consensus; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dog Diseases / prevention & control; Dogs; Doxycycline / therapeutic use; Leptospira / isolation & purification; Leptospirosis / diagnosis; Leptospirosis / drug therapy; Leptospirosis / microbiology; Leptospirosis / prevention & control; Leptospirosis / veterinary; Practice Guidelines as Topic; Zoonoses / microbiology
TL;DR: Diagnosis is based on acute and convalescent phase antibody titers by the microscopic agglutination test (MAT), with or without use of polymerase chain reaction assays, and the MAT does not accurately predict the infecting serogroup. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2010 journal article

Effects of glucosamine–chondroitin sulfate supplementation on serum fructosamine concentration in healthy dogs

Journal of the American Veterinary Medical Association, 236(2), 183–186.

By: C. Lenox* & K. Lunn*

MeSH headings : Administration, Oral; Animals; Chondroitin Sulfates / administration & dosage; Chondroitin Sulfates / metabolism; Dogs / blood; Drug Therapy, Combination; Fructosamine / blood; Glucosamine / administration & dosage; Glucosamine / metabolism; Male
TL;DR: Results suggest that in healthy dogs, short-term (ie, 21 days) oral Glu-CS administration does not affect glycemic control or cause diabetes mellitus. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2010 chapter

Fever of Unknown Origin

In C. M. Kahn & S. Line (Eds.), The Merck Veterinary Manual (10th edition, pp. 924–927). Whitehouse Station, NJ: Merck & Co., Inc.

By: K. Lunn

Ed(s): C. Kahn & S. Line

Source: NC State University Libraries
Added: March 23, 2021

2010 journal article

Seroprevalence and Risk Factors for Canine H3N8 Influenza Virus Exposure in Household Dogs in Colorado

Journal of Veterinary Internal Medicine, 24(6), 1524–1527.

By: E. Barrell*, H. Pecoraro*, C. Torres-Henderson*, P. Morley*, K. Lunn* & G. Landolt*

MeSH headings : Animals; Colorado / epidemiology; Dog Diseases / epidemiology; Dog Diseases / virology; Dogs; Female; Influenza A Virus, H3N8 Subtype / isolation & purification; Male; Orthomyxoviridae Infections / epidemiology; Orthomyxoviridae Infections / veterinary; Orthomyxoviridae Infections / virology; Risk Factors; Seroepidemiologic Studies
TL;DR: CIV seroprevalence in household dogs in Colorado is low, although it has increased since 2004, and dogs boarded in kennels or attending daycare might be at an increased risk of CIV infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2009 journal article

Current perspectives on canine leptospirosis

In Practice, 31(3), 98–102.

By: P. Burr, K. Lunn* & P. Yam

TL;DR: The current understanding of leptospirosis in dogs is reviewed, and the available strategies for diagnosis and prevention are outlined. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2009 journal article

Use of a point-of-care urine drug test in a dog to assist in diagnosing barbiturate toxicosis secondary to ingestion of a euthanized carcass

Journal of Veterinary Emergency and Critical Care, 19(3), 286–291.

By: V. Campbell*, A. Butler* & K. Lunn*

author keywords: drug intoxication; endocrinology; hypoadrenocorticism; pharmacology anesthetics; toxicology; wildlife medicine
MeSH headings : Animals; Barbiturates / toxicity; Cadaver; Dog Diseases / chemically induced; Dog Diseases / urine; Dogs; Euthanasia; Goats; Male; Point-of-Care Systems
TL;DR: Urine drug testing is a fast, easy, and point-of-care test that may be useful in dogs to assist in the diagnosis of barbiturate intoxication. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2008 chapter

Canine Influenza

In J. D. Bonagura & R. W. Kirk (Eds.), Kirk’s Current Veterinary Therapy (14th Edition, pp. 1291–1294). Philadelphia, PA: Saunders Elsevier.

By: G. Landolt & K. Lunn

Ed(s): J. Bonagura & R. Kirk

Source: NC State University Libraries
Added: March 23, 2021

2008 chapter

Managing the Patient with Polyuria and Polydipsia

In J. D. Bonagura & R. W. Kirk (Eds.), Kirk’s Current Veterinary Therapy (14th Edition, pp. 844–850). Philadelphia, PA: Saunders Elsevier.

By: K. Lunn

Ed(s): J. Bonagura & R. Kirk

Source: NC State University Libraries
Added: March 23, 2021

2008 journal article

Unilateral improvement in glomerular filtration rate after permanent drainage of a perinephric pseudocyst in a cat

Journal of Feline Medicine and Surgery, 10(3), 280–283.

By: K. McCord, P. Steyn* & K. Lunn*

MeSH headings : Animals; Cat Diseases / diagnostic imaging; Cat Diseases / surgery; Cats; Drainage / veterinary; Glomerular Filtration Rate / veterinary; Kidney Diseases, Cystic / surgery; Kidney Diseases, Cystic / veterinary; Male; Radionuclide Imaging / veterinary; Treatment Outcome; Ultrasonography, Interventional / veterinary
TL;DR: A 12-year-old, 6 kg, castrated male Siamese-cross cat was referred for investigation of an abdominal mass and found to have a left perinephric pseudocyst (PNP), accompanied by azotemia, with a small right kidney detected on ultrasound. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020

2007 journal article

Diagnostic use of cytologic examination of bone marrow from dogs with thrombocytopenia: 58 cases (1994–2004)

Journal of the American Veterinary Medical Association, 231(10), 1540–1544.

By: M. Miller* & K. Lunn*

MeSH headings : Animals; Bone Marrow Cells / cytology; Bone Marrow Cells / pathology; Cytological Techniques / veterinary; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / pathology; Dogs; Female; Male; Predictive Value of Tests; Prognosis; Retrospective Studies; Severity of Illness Index; Thrombocytopenia / diagnosis; Thrombocytopenia / pathology; Thrombocytopenia / veterinary
TL;DR: Cytologic examination of bone marrow is unlikely to provide specific diagnostic or prognostic information in dogs with severe thrombocytopenia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

2007 chapter

Fever of Unknown Origin

In C. M. Kahn & S. Line (Eds.), The Merck/Merial Manual for Pet Health. Whitehouse Station, NJ: Merck & Co.

By: K. Lunn

Ed(s): C. Kahn & S. Line

Source: NC State University Libraries
Added: March 23, 2021

2007 journal article

Infectious disease updates

Advances in Small Animal Medicine and Surgery, 20(6), 1–2.

By: K. Lunn*

TL;DR: All antibiotic classes except the macrolides and first generation cephalosporins were associated with CDI; carbapenems and 2nd and 3rd generation cesporins conferred the highest risk. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020

2007 journal article

Normal and abnormal water balance: hyponatremia and hypernatremia

Compendium on Continuing Education for the Practising Veterinarian- North American Edition, 29(10), 589–609.

By: K. James & K. Lunn

Source: NC State University Libraries
Added: March 29, 2021

2007 journal article

Normal and abnormal water balance: polyuria and polydipsia

Compendium on Continuing Education for the Practising Veterinarian- North American Edition, 29(10), 612–624.

By: K. James & K. Lunn

Source: NC State University Libraries
Added: March 23, 2021

2006 journal article

Detection and Quantification of Equine Herpesvirus-1 Viremia and Nasal Shedding by Real-Time Polymerase Chain Reaction

Journal of Veterinary Diagnostic Investigation, 18(4), 335–342.

By: S. Hussey*, R. Clark*, K. Lunn*, C. Breathnach*, G. Soboll*, J. Whalley*, D. Lunn*

author keywords: diagnosis; equine herpesvirus-1; real-time PCR
MeSH headings : Animals; Female; Herpesvirus 1, Equid / genetics; Herpesvirus 1, Equid / isolation & purification; Horse Diseases / diagnosis; Horse Diseases / virology; Horses / virology; Male; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Sensitivity and Specificity; Viremia / veterinary; Viremia / virology; Virus Latency; Virus Shedding
TL;DR: It is concluded that real-time PCR is a sensitive and quantitative test for EHV-1 nasal shedding and viremia and provides a valuable tool for E hvirus-1 surveillance, diagnosis of clinical disease, and investigation of vaccine efficacy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 27, 2019

2006 chapter

Fever

In C. E. Greene (Ed.), Infectious Diseases of the Dog and Cat (3rd Edition, pp. 1028–1037). St. Louis, MO: Saunders Elsevier.

By: K. Lunn

Ed(s): C. Greene

Source: NC State University Libraries
Added: March 29, 2021

2005 chapter

Fever of Unknown Origin

In C. M. Kahn (Ed.), The Merck Veterinary Manual (9th ed., pp. 821–824). Whitehouse Station, NJ: Merck & Co., Inc.

By: K. Lunn

Ed(s): C. Kahn

Source: NC State University Libraries
Added: March 29, 2021

2001 journal article

Fever of unknown origin: a systematic approach to diagnosis

Compendium on Continuing Education for the Practising Veterinarian- North American Edition, 23(11), 976–994.

By: K. Lunn

Source: NC State University Libraries
Added: March 29, 2021

1997 journal article

Journal of Neurocytology, 26(5), 267–281.

By: K. Lunn*, M. Clayton* & I. Duncan*

MeSH headings : Aging; Animals; Axons / pathology; Cell Count; Central Nervous System Diseases / pathology; Central Nervous System Diseases / physiopathology; Endoplasmic Reticulum, Smooth / pathology; Microscopy, Electron; Microtubules / pathology; Myelin Sheath / pathology; Myelin Sheath / physiology; Neuroglia / pathology; Oligodendroglia / pathology; Optic Nerve / pathology; Pyramidal Tracts / pathology; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Spinal Cord / pathology
TL;DR: It is suggested that the microtubule abnormality in the taiep mutant inhibits both the initial formation and the long-term maintenance of myelin by the oligodendrocyte. (via Semantic Scholar)
Source: Crossref
Added: September 16, 2020

1997 journal article

Microtubule Organization and Stability in the Oligodendrocyte

The Journal of Neuroscience, 17(13), 4921–4932.

By: K. Lunn*, P. Baas* & I. Duncan

MeSH headings : Animals; Cell Polarity / drug effects; Cells, Cultured; Fluorescent Antibody Technique, Indirect; Microscopy, Electron; Microtubules / drug effects; Microtubules / physiology; Microtubules / ultrastructure; Nocodazole / pharmacology; Oligodendroglia / drug effects; Oligodendroglia / ultrastructure; Rats; Rats, Sprague-Dawley
TL;DR: The results suggest that oligodendrocyte microtubules can be resolved into at least three distinct microtubule populations that differ in their kinetics of depolymerization in the presence of nocodazole. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

1995 journal article

Myelin mutants: New models and new observations

Microscopy Research and Technique, 32(3), 183–203.

By: K. Lunn*, M. Fanarraga* & I. Duncan*

author keywords: X-LINKED; AUTOSOMAL RECESSIVE; PNS; CNS; OLIGODENDROCYTE; SCHWANN CELL
MeSH headings : Animals; Cricetinae; Dogs; Mesocricetus; Mice; Mutation; Myelin Basic Protein / analysis; Myelin Proteolipid Protein / analysis; Myelin Proteolipid Protein / genetics; Myelin Sheath / chemistry; Myelin Sheath / pathology; Myelin Sheath / physiology; Rabbits; Rats; Rats, Sprague-Dawley
TL;DR: A number of new myelin mutants which have recently been described are presented and the range of abnormalities in the mutants described includes defects in specific myelin proteins, suspected abnormalities in membrane formation, and apparent defects of the oligodendrocyte cytoskeleton. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

1995 journal article

Oligodendrocyte survival and function in the long-lived strain of the myelin deficient rat

Journal of Neurocytology, 24(10), 745–762.

By: I. Duncan*, N. Nadon*, R. Hoffman*, K. Lunn*, C. Csiza* & M. Wells*

MeSH headings : Animals; Astrocytes / pathology; Base Sequence; Blotting, Northern; Cell Survival; Female; Glial Fibrillary Acidic Protein / analysis; Glial Fibrillary Acidic Protein / genetics; Male; Microscopy, Electron; Molecular Sequence Data; Myelin Basic Protein / genetics; Myelin Proteolipid Protein / deficiency; Myelin Sheath / pathology; Myelin Sheath / physiology; Nerve Fibers, Myelinated / pathology; Oligodendroglia / pathology; Oligodendroglia / physiology; Optic Nerve / pathology; RNA, Messenger / analysis; RNA, Messenger / metabolism; Rats; Rats, Mutant Strains; Spinal Cord / pathology
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

1993 journal article

Insulin-secreting tumours of the canine pancreas: Clinical and pathological features of 11 cases

Journal of Small Animal Practice, 34(7), 325–331.

By: J. Dunn*, D. Bostock*, M. Herrtage*, K. Jackson* & M. Walker

TL;DR: The clinical and pathological features of 11 dogs with insulin-secreting tumours of the pancreas are described and a suggestion that tumours with a high mitotic count carried a worse prognosis is suggested. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2021

1992 journal article

Diagnosis of insulinoma in the dog: A study of 11 cases

Journal of Small Animal Practice, 33(11), 514–520.

By: J. Dunn*, M. Heath*, M. Herrtage*, K. Jackson* & M. Walker

TL;DR: It appears that insulin-secreting tumours retain a degree of responsiveness to a glucose challenge and that the IVGTT, using a dose of 0–5 g glucose/kg bodyweight, is a useful diagnostic procedure in dogs with insulinoma. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2021

1992 journal article

The taiep rat: A myelin mutant with an associated oligodendrocyte microtubular defect

Journal of Neurocytology, 21(12), 870–884.

By: I. Duncan*, K. Lunn*, B. Holmgren*, R. Urba-Holmgren* & L. Brignolo-Holmes*

MeSH headings : Animals; Central Nervous System Diseases / genetics; Central Nervous System Diseases / pathology; Microscopy, Electron; Microtubules / pathology; Myelin Sheath / physiology; Oligodendroglia / ultrastructure; Rats; Rats, Mutant Strains
TL;DR: It is proposed that the microtubular defect in oligodendrocytes results in a disruption of the normal myelination process in certain areas of the CNS of this mutant, and eventually leads to failure of maintenance of the myelin sheath. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 16, 2020

1991 journal article

Hypercalcaemia in the dog: a study of 40 cases

Journal of Small Animal Practice, 32(11), 564–571.

By: J. Elliott*, J. Dobson*, J. Dunn*, M. Herrtage* & K. Jackson*

TL;DR: Forty dogs referred to the University Department of Clinical Veterinary Medicine, Cambridge for medical and oncological conditions between 1985 and 1990 were found to be hypercalcaemia, with lymphoproliferative disease with multicentric lymphoma occurring most commonly. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2021

1991 journal article

Preferential denervation of the adductor muscles of the equine larynx I: muscle pathology

Equine Veterinary Journal, 23(2), 94–98.

By: I. Duncan*, J. Amundson*, P. Cuddon*, R. Sufit*, K. Jackson* & W. Lindsay*

MeSH headings : Analysis of Variance; Animals; Atrophy; Female; Horse Diseases / pathology; Horses; Hypertrophy; Laryngeal Diseases / pathology; Laryngeal Diseases / veterinary; Laryngeal Muscles / innervation; Laryngeal Muscles / pathology; Laryngoscopy / veterinary; Male; Retrospective Studies
TL;DR: The propensity for denervation of the adductor muscles should provide clues as to the pathogenesis and natural history of horses with sub-clinical laryngeal disease and ILH. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2021

1991 journal article

Preferential denervation of the adductor muscles of the equine larynx II: Nerve pathology

Equine Veterinary Journal, 23(2), 99–103.

By: I. Duncan*, P. Reifenrath*, K. Jackson* & M. Clayton*

MeSH headings : Animals; Hemiplegia / pathology; Hemiplegia / veterinary; Horse Diseases / pathology; Horses; Laryngeal Diseases / pathology; Laryngeal Diseases / veterinary; Laryngeal Muscles / innervation; Laryngeal Muscles / pathology; Laryngeal Nerves / pathology; Laryngoscopy / veterinary; Vocal Cord Paralysis / pathology; Vocal Cord Paralysis / veterinary
TL;DR: While no simple morphometrical feature was found to explain the selective muscle denervation, the greater loss of large diameter myelinated fibres in the adductor branches confirms the earlier observation of adductionor muscle susceptibility in the neuropathy of ILH. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2021

1989 chapter

Hypomyelination in Dogs

In R. W. Kirk (Ed.), Current Veterinary Therapy (10th edition, pp. 834–838). Philadelphia, PA: W B Saunders Co.

By: K. Jackson & I. Duncan

Ed(s): R. Kirk

Source: NC State University Libraries
Added: March 29, 2021

1989 journal article

Hypomyelination in the neonatal rat central and peripheral nervous systems following tellurium intoxication

Acta Neuropathologica, 78(3), 301–309.

By: K. Jackson*, J. Hammang*, S. Worth* & I. Duncan*

MeSH headings : Animals; Central Nervous System / physiopathology; Female; Microscopy, Electron; Myelin Sheath / drug effects; Myelin Sheath / physiopathology; Optic Nerve / pathology; Optic Nerve / ultrastructure; Peripheral Nerves / physiopathology; Rats; Rats, Inbred Strains; Sciatic Nerve / pathology; Sciatic Nerve / ultrastructure; Spinal Cord / pathology; Spinal Cord / ultrastructure; Tellurium / toxicity
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2021

1988 journal article

Cell kinetics and cell death in the optic nerve of the myelin deficient rat

Journal of Neurocytology, 17(5), 657–670.

By: K. Jackson* & I. Duncan*

MeSH headings : Age Factors; Animals; Autoradiography; Cell Count; Cell Division; Cell Survival; Demyelinating Diseases / pathology; Demyelinating Diseases / physiopathology; Microscopy, Electron; Neuroglia / pathology; Neuroglia / ultrastructure; Optic Nerve / pathology; Optic Nerve / physiopathology; Optic Nerve / ultrastructure; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Thymidine
TL;DR: Results suggest a defect in the md rat oligodendrocyte, resulting in a protracted uptake of thymidine and increased cell death, which may reveal more about the role of myelin proteins in the CNS, and the specific cellular defect(s) in this mutant. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2021

1988 journal article

Transplantation of oligodendrocytes and Schwann cells into the spinal cord of the myelin-deficient rat

Journal of Neurocytology, 17(3), 351–360.

By: I. Duncan*, J. Hammang*, K. Jackson*, P. Wood*, R. Bunge & L. Langford*

MeSH headings : Animals; Cells, Cultured; Female; Male; Microscopy, Electron; Myelin Sheath / physiology; Neuroglia / transplantation; Oligodendroglia / transplantation; Rats; Rats, Mutant Strains; Schwann Cells / transplantation; Spinal Cord / cytology; Spinal Cord / ultrastructure
TL;DR: Injection of cultured Schwann cells resulted in extensive myelination of axons in the dorsal columns by these cells, which was interpreted as evidence of the origin of this myelin from donor oligodendrocytes, as the md rat has an abnormality in synthesis of this protein. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: October 23, 2020

1987 journal article

Myelin mosaicism in female heterozygotes of the canine shaking pup and myelin-deficient rat mutants

Brain Research, 402(1), 168–172.

By: I. Duncan*, J. Hammang* & K. Jackson*

MeSH headings : Animals; Central Nervous System / pathology; Central Nervous System Diseases / genetics; Dogs; Female; Genetic Linkage; Heterozygote; Mosaicism; Myelin Sheath / physiology; Optic Nerve / pathology; Rats; Rats, Mutant Strains; Spinal Cord / pathology; X Chromosome
TL;DR: Female heterozygote dogs can develop a marked tremor which disappears with age and in both the rat and dog, abnormal oligodendrocytes with distended rough endoplasmic reticulum are found in the abnormal patches and are a marker of the trait. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2021

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