Works (2)

Updated: July 5th, 2023 15:43

2014 article

The Comparative Toxicogenomics Database's 10th year anniversary: update 2015

Davis, A. P., Grondin, C. J., Lennon-Hopkins, K., Saraceni-Richards, C., Sciaky, D., King, B. L., … Mattingly, C. J. (2014, October 17). Nucleic Acids Research, Vol. 43, pp. D914–920.

By: A. Davis n, C. Grondin n, K. Lennon-Hopkins n, C. Saraceni-Richards n, D. Sciaky n, B. King*, T. Wiegers n, C. Mattingly n

MeSH headings : Databases, Chemical / history; Disease / etiology; Disease / genetics; Genomics / history; History, 21st Century; Internet; Phenotype; Toxicogenetics / history
topics (OpenAlex): Bioinformatics and Genomic Networks; Biomedical Text Mining and Ontologies; Computational Drug Discovery Methods
TL;DR: The prototype database originally described in its first report has transformed into a sophisticated resource used actively today to help scientists develop and test hypotheses about the etiologies of environmentally influenced diseases. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 article

A CTD-Pfizer collaboration: manual curation of 88 000 scientific articles text mined for drug-disease and drug-phenotype interactions

Davis, A. P., Wiegers, T. C., Roberts, P. M., King, B. L., Lay, J. M., Lennon-Hopkins, K., … Mattingly, C. J. (2013, November 28). Database.

By: A. Davis n, T. Wiegers n, P. Roberts n, B. King n, J. Lay n, K. Lennon-Hopkins n, D. Sciaky n, R. Johnson n ...

MeSH headings : Cooperative Behavior; Data Mining; Databases, Factual; Disease; Drug Industry; Humans; Pharmaceutical Preparations / metabolism; Phenotype; Publications; Toxicogenetics
topics (OpenAlex): Biomedical Text Mining and Ontologies; Bioinformatics and Genomic Networks; Computational Drug Discovery Methods
TL;DR: A collaboration between safety researchers at Pfizer and the research team at the Comparative Toxicogenomics Database (CTD) to text mine and manually review a collection of 88 629 articles relating over 1 200 pharmaceutical drugs to their potential involvement in cardiovascular, neurological, renal and hepatic toxicity. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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