Works (3)

Updated: July 15th, 2023 13:30

2021 journal article

Transcriptomic, proteomic, and metabolomic analyses identify candidate pathways linking maternal cadmium exposure to altered neurodevelopment and behavior

SCIENTIFIC REPORTS, 11(1).

By: K. Hudson n, E. Shiver n, J. Yu*, S. Mehta n, D. Jima n, M. Kane*, H. Patisaul n, M. Cowley n

MeSH headings : Animals; Body Weight / drug effects; Body Weight / genetics; Cadmium / toxicity; Female; Fetal Development / drug effects; Fetal Development / genetics; Humans; Maternal Exposure; Metabolomics / methods; Mice; Mice, Inbred C57BL; Neurodevelopmental Disorders / chemically induced; Neurodevelopmental Disorders / genetics; Placenta / drug effects; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Proteomics / methods; Transcriptome / genetics
TL;DR: The identification of multiple pathways perturbed in the developing brain provides a basis for future studies determining the mechanistic links between maternal Cd exposure and altered neurodevelopment and behavior. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 30, 2021

2019 journal article

Maternal cadmium exposure in the mouse leads to increased heart weight at birth and programs susceptibility to hypertension in adulthood

SCIENTIFIC REPORTS, 9(1).

By: K. Hudson n, S. Belcher n & M. Cowley n

Contributors: K. Hudson n, S. Belcher n & M. Cowley n

MeSH headings : Animals; Animals, Newborn; Body Weight / drug effects; Cadmium / adverse effects; Disease Models, Animal; Female; Gene Expression Profiling / methods; Gene Expression Regulation / drug effects; Gene Regulatory Networks / drug effects; Heart / anatomy & histology; Heart / drug effects; Hypotension / chemically induced; Hypotension / genetics; Maternal Exposure / adverse effects; Metabolic Networks and Pathways / drug effects; Mice; Organ Size / drug effects; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Sequence Analysis, RNA
TL;DR: It is proposed that a maternal Cd exposure-induced iron deficiency leads to altered cellular metabolic pathways and hypoxic conditions during fetal development; this stress may contribute to increased heart weight at birth and the programming of susceptibility to hypertension in adulthood. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 7, 2019

2018 journal article

Effects of cadmium exposure on DNA methylation at imprinting control regions and genome-wide in mothers and newborn children

Environmental Health Perspectives, 126(3).

Source: NC State University Libraries
Added: August 6, 2018

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