Works (3)
Updated: July 15th, 2023 13:30
2021 journal article
Transcriptomic, proteomic, and metabolomic analyses identify candidate pathways linking maternal cadmium exposure to altered neurodevelopment and behavior
SCIENTIFIC REPORTS, 11(1).
MeSH headings : Animals; Body Weight / drug effects; Body Weight / genetics; Cadmium / toxicity; Female; Fetal Development / drug effects; Fetal Development / genetics; Humans; Maternal Exposure; Metabolomics / methods; Mice; Mice, Inbred C57BL; Neurodevelopmental Disorders / chemically induced; Neurodevelopmental Disorders / genetics; Placenta / drug effects; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Proteomics / methods; Transcriptome / genetics
TL;DR:
The identification of multiple pathways perturbed in the developing brain provides a basis for future studies determining the mechanistic links between maternal Cd exposure and altered neurodevelopment and behavior.
(via Semantic Scholar)
open access via www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 30, 2021
2019 journal article
Maternal cadmium exposure in the mouse leads to increased heart weight at birth and programs susceptibility to hypertension in adulthood
SCIENTIFIC REPORTS, 9(1).
Contributors: n, S. Belcher n & M. Cowley n
MeSH headings : Animals; Animals, Newborn; Body Weight / drug effects; Cadmium / adverse effects; Disease Models, Animal; Female; Gene Expression Profiling / methods; Gene Expression Regulation / drug effects; Gene Regulatory Networks / drug effects; Heart / anatomy & histology; Heart / drug effects; Hypotension / chemically induced; Hypotension / genetics; Maternal Exposure / adverse effects; Metabolic Networks and Pathways / drug effects; Mice; Organ Size / drug effects; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Sequence Analysis, RNA
TL;DR:
It is proposed that a maternal Cd exposure-induced iron deficiency leads to altered cellular metabolic pathways and hypoxic conditions during fetal development; this stress may contribute to increased heart weight at birth and the programming of susceptibility to hypertension in adulthood.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 7, 2019
2018 journal article
Effects of cadmium exposure on DNA methylation at imprinting control regions and genome-wide in mothers and newborn children
Environmental Health Perspectives, 126(3).
Source: NC State University Libraries
Added: August 6, 2018
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