@article{cassady_balko_bailey_posner_robertson_minter_2023, title={EVALUATION OF OSCILLOMETRIC BLOOD PRESSURE MEASUREMENT USING A FINGER CUFF IN ANESTHETIZED CHIMPANZEES (PAN TROGLODYTES)}, volume={54}, ISSN={["1937-2825"]}, DOI={10.1638/2021-0001}, abstractNote={Abstract: Cardiovascular disease is common among chimpanzees (Pan troglodytes), and serial blood pressure monitoring in conscious animals may improve disease surveillance and guide hypertension treatment strategies. The objective of this study was to compare the accuracy of a noninvasive, oscillometric blood pressure monitor using a finger blood pressure cuff with invasively measured blood pressure in anesthetized chimpanzees. Twelve chimpanzees were anesthetized with tiletamine–zolazepam intramuscularly, intubated, and maintained on inhaled isoflurane to effect. Blood pressure measurements, which included systolic arterial pressure (SAP), mean arterial pressure (MAP), and diastolic arterial pressure (DAP), were collected simultaneously from an oscillometric blood pressure cuff placed on a forelimb digit (FBP) and a direct arterial catheter (IBP) every 5–10 min while anesthetized. One hundred paired samples were collected, and results were compared using Bland–Altman plots and analysis. FBP showed good agreement with IBP for SAP, MAP, and DAP but consistently overestimated values compared with IBP. FBP may be useful for serial blood pressure monitoring in conscious chimpanzees.}, number={1}, journal={JOURNAL OF ZOO AND WILDLIFE MEDICINE}, author={Cassady, Katherine R. and Balko, Julie A. and Bailey, Kate M. and Posner, Lysa P. and Robertson, James B. and Minter, Larry J.}, year={2023}, month={Mar}, pages={16–22} }
 @article{schlake_cassady_gruber_minter_2023, title={Effect of Prolonged Serum Storage Time and Varied Temperatures on Biochemical Values in African Savanna Elephants (<i>Loxodonta africana</i>)}, volume={4}, ISSN={["2673-5636"]}, DOI={10.3390/jzbg4010002}, abstractNote={Blood samples are routinely collected from wild populations in remote locations with limited electricity, minimal diagnostic capabilities, and extreme environmental conditions. Under these conditions, serum samples may be stored for prolonged time under varied temperatures prior to processing, which could affect the ability to interpretation the results. This study’s objective was to evaluate the effects of delayed processing of serum samples and varied storage temperatures on biochemical values in African savanna elephants (Loxodonta africana). Blood samples were collected from six elephants managed by the North Carolina Zoo. For each elephant, seven red top tubes were collected. One serum sample for each elephant was analyzed on Day 0 (control group). The remaining samples were stored under different temperatures including room temperature (23 °C), refrigeration (2.2 °C), and incubation (32.2 °C), with samples from each temperature group being analyzed on Day 5 and Day 10. Many of analytes (10 out of 18) did not change significantly regardless of storage temperature or time. Refrigeration improved stability in an additional four analytes over prolonged storage. We conclude that if serum is properly separated shortly after collection, many serum biochemical analytes can be accurately measured even after suboptimal serum storage, but refrigeration and prompt evaluation are still required for some analytes.}, number={1}, journal={JOURNAL OF ZOOLOGICAL AND BOTANICAL GARDENS}, author={Schlake, Emily L. and Cassady, Katherine R. and Gruber, Erika J. and Minter, Larry J.}, year={2023}, month={Mar}, pages={12–20} }
 @article{cassady_minter_gruber_2023, title={Performance of a manually operated salad spinner centrifuge for serum separation in the healthy domestic horse (Equus caballus) and southern white rhinoceros (Ceratotherium simum)}, volume={7}, ISSN={["1939-165X"]}, url={https://doi.org/10.1111/vcp.13290}, DOI={10.1111/vcp.13290}, abstractNote={Abstract}, journal={VETERINARY CLINICAL PATHOLOGY}, author={Cassady, Katherine R. and Minter, Larry J. and Gruber, Erika J.}, year={2023}, month={Jul} }
 @article{salger_cassady_reading_noga_2016, title={A Diverse Family of Host-Defense Peptides (Piscidins) Exhibit Specialized Anti-Bacterial and Anti-Protozoal Activities in Fishes}, volume={11}, ISSN={["1932-6203"]}, DOI={10.1371/journal.pone.0159423}, abstractNote={Conventional antibiotics and other chemical-based drugs are currently one of the most common methods used to control disease-related mortality in animal agriculture. Use of the innate immune system to decrease disease related mortalities is a novel alternative to conventional drugs. One component of the innate immune system is the host-defense peptides, also known as antimicrobial peptides. Host-defense peptides are typically small, amphipathic, α-helical peptides with a broad-spectrum of action against viral, bacterial, fungal, and/or protozoal pathogens. Piscidins are host-defense peptides first discovered in the hybrid striped bass (white bass, Morone chrysops, x striped bass, M. saxatilis). In this paper we identify four new piscidin isoforms in the hybrid striped bass and describe their tissue distributions. We also determine the progenitor species of origin of each piscidin (orthology) and propose a revised nomenclature for this newly described piscidin family based on a three class system. The Class I piscidins (22 amino acids in length; striped bass and white bass piscidin 1 and piscidin 3) show broad-spectrum activity against bacteria and ciliated protozoans, while the Class III piscidins (55 amino acids in length; striped bass and white bass piscidin 6 and striped bass piscidin 7) primarily show anti-protozoal activity. The Class II piscidins (44–46 amino acids in length; striped bass and white bass piscidin 4 and white bass piscidin 5) have a level of activity against bacteria and protozoans intermediate to Classes I and III. Knowledge of piscidin function and activity may help in the future development of disease-resistant lines of striped bass and white bass that could be used to produce superior hybrids for aquaculture.}, number={8}, journal={PLOS ONE}, author={Salger, Scott A. and Cassady, Katherine R. and Reading, Benjamin J. and Noga, Edward J.}, year={2016}, month={Aug} }