Works (7)

Updated: April 30th, 2024 05:03

2024 journal article

Evaluating Bacterial Nanocellulose Interfaces for Recording Surface Biopotentials from Plants

SENSORS, 24(7).

By: J. Reynolds n, M. Wilkins n, D. Martin n, M. Taggart n, K. Rivera*, M. Tunc-Ozdemir*, T. Rufty n, E. Lobaton n, A. Bozkurt n, M. Daniele n

author keywords: nanocellulose; electrophysiology; plant; electrode
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 15, 2024

2023 journal article

Hypoxia Primes Human ISCs for Interleukin-Dependent Rescue of Stem Cell Activity


By: K. Rivera n, R. Bilton, J. Burclaff n, M. Czerwinski*, J. Liu*, J. Trueblood*, C. Hinesley*, K. Breau* ...

author keywords: Inflammatory Hypoxia; Microphysiological System; Intestinal Stem Cells; Stem Cell Priming; Oxygen Sensor; Cytokines
TL;DR: A new microphysiological system (MPS) is presented to investigate how hypoxia affects hISCs from healthy donors and test the hypothesis that prolongedHypoxia modulates how hISC respond to inflammation-associated interleukins (ILs) and has important implications for understanding intestinal epithelial regeneration mechanisms caused by inflammatory hypoxIA. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 6, 2023

2021 journal article

Monitoring of random microvessel network formation by in-line sensing of flow rates: A numerical and in vitro investigation


By: V. Pozdin*, P. Erb n, M. Downey n, K. Rivera n & M. Daniele n

author keywords: Microphysiological systems; Microfluidics; Equivalent circuit; Fluid mechanics; Vascular mechanics; Microvessels; Fluid networks
TL;DR: A strategy to monitor the dynamic formation of microscale fluid networks, which can be translated to the monitoring of microvasculature development in engineered tissue constructs and illustrates the potential to precisely and non-destructively monitor microvessel network development and volumetric changes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: October 18, 2021

2019 journal article

IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid Model


By: B. Zwarycz*, A. Gracz*, K. Rivera n, I. Williamson n, L. Samsa*, J. Starmer*, M. Daniele n, L. Salter-Cid*, Q. Zhao*, S. Magness n

author keywords: Intestinal Stem Cells; Interleukin-22; Inflammatory Bowel Disease
MeSH headings : Animals; Biomarkers / metabolism; Cell Lineage / drug effects; Cell Proliferation / drug effects; Cell Self Renewal / drug effects; Cellular Microenvironment / drug effects; Computer Simulation; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Ileum / cytology; Inflammatory Bowel Diseases / pathology; Interleukins / pharmacology; Mice, Inbred C57BL; Models, Biological; Organoids / cytology; Organoids / drug effects; Organoids / metabolism; Receptors, Interleukin / metabolism; Serum / metabolism; Stem Cells / cytology; Stem Cells / drug effects; Stem Cells / metabolism
TL;DR: Increased IL22 limits ISC expansion in favor of increased TA progenitor cell expansion, and chronically increased IL22 levels, similar to predicted microenvironment levels, showed increases in proliferative cells in the TA zone with no increase in ISCs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: January 14, 2019

2019 journal article

Integrated phosphorescence-based photonic biosensor (iPOB) for monitoring oxygen levels in 3D cell culture systems


By: K. Rivera n, V. Pozdin n, A. Young n, P. Erb n, N. Wisniewski*, S. Magness n, M. Daniele n

author keywords: Oxygen; Microdevice; Organs-on-chips; Oxygen biosensor; Biosensors; Hypoxia
MeSH headings : Biosensing Techniques; Cell Culture Techniques; Cell Hypoxia; Cell Line, Tumor; Humans; Luminescent Measurements / methods; Oxygen / chemistry; Oxygen / metabolism; Photons
TL;DR: The design and engineering of a system to remotely monitor and control oxygen concentration inside a device for 3D cell culture is reported, integrating a photonic oxygen biosensor into the 3D tissue scaffold and regulate oxygen concentration via the control of purging gas flow. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: December 3, 2018

2019 review

Measuring and regulating oxygen levels in microphysiological systems: design, material, and sensor considerations

[Review of ]. ANALYST, 144(10), 3190–3215.

By: K. Rivera n, M. Yokus n, P. Erb n, V. Pozdin n & M. Daniele n

MeSH headings : Animals; Cell Line; Humans; Lab-On-A-Chip Devices; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Models, Biological; Oxygen / analysis; Oxygen / metabolism
TL;DR: Comparisons of organ-specific MPS that do and do not consider oxygen microenvironments are offered and materials used in microphysiological models are analyzed in terms of their ability to control oxygen. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 22, 2019

2019 review

Monitoring of Microphysiological Systems: Integrating Sensors and Real-Time Data Analysis toward Autonomous Decision-Making

[Review of ]. ACS SENSORS, 4(6), 1454–1464.

By: A. Young n, K. Rivera n, P. Erb n & M. Daniele n

author keywords: microphysiological system (MPS); organ-on-chip; biosensor; real-time analysis; data; cyber-physical system
MeSH headings : Data Analysis; Humans; Lab-On-A-Chip Devices; Machine Learning; Microchip Analytical Procedures / methods; Monitoring, Physiologic / instrumentation; Monitoring, Physiologic / methods
TL;DR: In this Perspective, three stages of microphysiological system monitoring, including process, development, and function, are assessed and the unique features and remaining technical challenges for the required sensors are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 22, 2019

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