@article{fowler_johannes_o'connor_collins_lustgarten_yuan_weishaar_sullivan_hume_mahoney_et al._2020, title={Ecological level analysis of primary lung tumors in dogs and cats and environmental radon activity}, volume={34}, ISSN={["1939-1676"]}, DOI={10.1111/jvim.15936}, abstractNote={AbstractBackgroundEpidemiologic studies suggest residential radon exposure might increase the risk of primary lung cancer in people, but these studies are limited by subject mobility. This limitation might be overcome by evaluating the association in pets.HypothesisPrimary pulmonary neoplasia (PPN) rate is higher in dogs and cats residing in counties with a high radon exposure risk (Environmental Protection Agency [EPA] zone 1) compared to zones 2 (moderate radon exposure risk) and 3 (low radon exposure risk).AnimalsSix hundred ninety client‐owned dogs and 205 client‐owned cats with PPN.MethodsRetrospective review of medical records at 10 veterinary colleges identified dogs and cats diagnosed with PPN between 2010 and 2015. Each patient's radon exposure was determined by matching the patient's zip code with published county radon exposure risk. County level PPN rates were calculated using the average annual county cat and dog populations. The PPN counts per 100 000 dog/cat years at risk (PPN rates) were compared across radon zones for each species.ResultsThe PPN rate ratio in counties in high radon zone (1) was approximately 2‐fold higher than in counties in lower radon zones for dogs (rate ratio zone 1 to 2, 2.49; 95% confidence interval [CI], 1.56‐4.00; rate ratio zone 1 to 3, 2.29; 95% CI, 1.46‐3.59) and cats (rate ratio zone 1 to 2, 2.13; 95% CI, 0.95‐4.79; zone 1 to 3, 1.81; 95% CI, 0.9‐3.61).Conclusions and Clinical ImportanceExposure to household radon might play a role in development of PPN in dogs and cats.}, number={6}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Fowler, Brittany L. and Johannes, Chad M. and O'Connor, Annette and Collins, Deanna and Lustgarten, Jonathan and Yuan, Chaohui and Weishaar, Kristen and Sullivan, Kelly and Hume, Kelly R. and Mahoney, Jennifer and et al.}, year={2020}, month={Nov}, pages={2660–2670} }
 @article{eisemann_lewis_broome_sullivan_boyd_odle_harrell_2014, title={Lysine requirement of 1.5-5.5 kg pigs fed liquid diets}, volume={54}, ISSN={["1836-5787"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84897497474&partnerID=MN8TOARS}, DOI={10.1071/an12280}, abstractNote={An experiment was conducted to define the lysine requirement of neonatal pigs fed a liquid diet up to 5.5 kg bodyweight (BW). Neonatal pigs, 1–2 days old, with an initial bodyweight of 1.63 ± 0.04 kg, were randomly allotted to 10 isocaloric diets varying in lysine concentration from 0.76 to 1.62 g lysine/MJ gross energy (GE). Diets were formulated using whey protein concentrate and casein as protein sources and contained similar balance of indispensable amino acids. On day 1 of the experiment, pigs were fed 350 g liquid diet/kg metabolic bodyweight (BW0.75) according to the average BW of all pigs. On day 2, feeding rate was increased to 400 g/kg BW0.75. Increments were 100 g/kg BW0.75 per day for the subsequent 3 days until pigs reached 700 g/kg BW0.75 on day 5. Thereafter, feed was offered to pigs at a common feeding level of 700 g/kg BW0.75 each day until they reached 5.5 kg BW. Feed intake and BW were measured daily. Concentration of fat in the carcass decreased (P < 0.05) and the ratio of crude protein (CP) to fat in the carcass increased (P < 0.05) linearly as lysine inclusion increased. Both average daily gain and CP accretion increased (quadratic, P < 0.05), whereas fat accretion decreased (quadratic, P < 0.05) as lysine inclusion increased. Using the maximum point of the quadratic function, the estimated dietary lysine required for maximal growth (271 g/day) and CP accretion (45.2 g/day) was 1.41 and 1.32 g lysine/MJ GE, respectively. The dietary lysine required, estimating the requirement at the lower limit of the 95% confidence interval for CP accretion of 42.9 g/day, was 1.12 g lysine/MJ GE. Gross efficiency of CP deposition (CP deposition/CP intake) achieved a maximum of 0.85 at 1.01 g lysine/MJ GE.}, number={5}, journal={ANIMAL PRODUCTION SCIENCE}, author={Eisemann, J. H. and Lewis, H. E. and Broome, A. I. and Sullivan, K. and Boyd, R. D. and Odle, J. and Harrell, R. J.}, year={2014}, pages={608–615} }
 @article{sullivan_freeman_van heugten_ange-van heugten_wolfe_poore_2012, title={Impact of two types of complete pelleted, wild ungulate feeds and two pelleted feed to hay ratios on the development of urolithogenic compounds in meat goats as a model for giraffes}, volume={97}, ISSN={0931-2439}, url={http://dx.doi.org/10.1111/j.1439-0396.2012.01297.x}, DOI={10.1111/j.1439-0396.2012.01297.x}, abstractNote={SummaryUrolith formation has been documented in giraffes and goats. As research in giraffes poses logistical challenges, 16 buck goats were used as a model. The impact of two commercially available, pelleted feeds used for giraffes, ADF‐16 and Wild Herbivore (WH), as well as the impact of alfalfa hay and pellet proportions (20% hay:80% pellets, 80P or 80% hay:20% pellet, 20P) on the formation of urolithogenic precursors in goat urine was accomplished in a 2 × 2 factorial balance study. Complete diets contained 0.60, 0.32, 0.35 and 0.26% phosphorus (P) with calcium:P ratios of 1.60, 4.16, 3.06 and 5.23, for 80P‐ADF‐16, 20P‐ADF‐16, 80P‐WH and 20P‐WH respectively. Total faeces and urine were collected over two 5‐day periods to assess N and mineral balance. Fresh urine samples were collected and evaluated microscopically for urolithic crystal content. Urinary nitrogen (N) was lower and N retention was higher in goats fed 80P diets (p < 0.05). Intake of P was greatest for goats fed 80P‐ADF‐16; however, urinary P excretion and P retention were not affected by treatment. Crystal scores were higher in animals receiving 80P diets (p = 0.08), with crystals being composed predominantly of calcium phosphate. Urine pH was alkaline (>8) for all treatments. Urinary P concentration, a risk factor for urolithiasis, was highest (p ≤ 0.06) in the 80P‐ADF‐16 treatment (0.38 vs. 0.01, 0.02 and 0.04 mg/dl for 20P‐ADF‐16, 80P‐WH and 20P‐WH respectively), reflecting its highest dietary P level. Further investigation is recommended to determine the long‐term effects of these diets on urolithogenic compound formation.}, number={3}, journal={Journal of Animal Physiology and Animal Nutrition}, publisher={Wiley}, author={Sullivan, K. and Freeman, S. and van Heugten, E. and Ange-van Heugten, K. and Wolfe, B. and Poore, M. H.}, year={2012}, month={Apr}, pages={566–576} }