Leigh Anne Mickelson-Young

Works (5)

Updated: April 5th, 2024 09:32

2021 journal article

Population diversity of cassava mosaic begomoviruses increases over the course of serial vegetative propagation

Journal of General Virology, 102(7).

By: C. Aimone n, E. Lavington*, J. Hoyer*, D. Deppong n, L. Mickelson-Young n, A. Jacobson*, G. Kennedy n, I. Carbone n, L. Hanley-Bowdoin n, S. Duffy*

author keywords: cassava mosaic begomoviruses; vegetative propagation; viral diversity
MeSH headings : Base Sequence; Begomovirus / genetics; Begomovirus / physiology; Codon; DNA, Intergenic; DNA, Viral / genetics; Evolution, Molecular; Genetic Variation; Genome, Viral; Manihot / growth & development; Manihot / virology; Mutation; Plant Diseases / virology; Polymorphism, Single Nucleotide; Satellite Viruses / genetics; Satellite Viruses / physiology; Sequence Deletion; Temperature; Viral Proteins / genetics
TL;DR: It is found that vegetative propagation had a significant effect on viral nucleotide diversity, while temperature and a satellite DNA did not have measurable impacts in this study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 16, 2021

2020 journal article

Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots


By: E. Wear n, J. Song, G. Zynda, L. Mickelson-Young n, C. LeBlanc*, T. Lee n, D. Deppong n, G. Allen n ...

MeSH headings : Cell Nucleus / drug effects; Cell Nucleus / genetics; Centromere / drug effects; Centromere / genetics; DNA Replication / drug effects; DNA Replication / genetics; DNA Replication Timing / drug effects; DNA Replication Timing / genetics; DNA, Plant / drug effects; DNA, Plant / genetics; Deoxyuridine / analogs & derivatives; Deoxyuridine / pharmacology; Endocytosis / drug effects; Meristem / drug effects; Meristem / genetics; Mitosis / drug effects; Mitosis / genetics; Nucleosomes / drug effects; Plant Roots / drug effects; Plant Roots / genetics; Plant Roots / growth & development; S Phase / genetics; Zea mays / genetics; Zea mays / growth & development
Sources: Web Of Science, NC State University Libraries
Added: November 9, 2020

2018 article

Chromatin structure profile data from DNS-seq: Differential nuclease sensitivity mapping of four reference tissues of B73 maize (Zea mays L)

Turpin, Z. M., Vera, D. L., Savadel, S. D., Lung, P.-Y., Wear, E. E., Mickelson-Young, L., … Bass, H. W. (2018, October). DATA IN BRIEF, Vol. 20, pp. 358–363.

By: Z. Turpin*, D. Vera*, S. Savadel*, P. Lung*, E. Wear n, L. Mickelson-Young n, W. Thompson n, L. Hanley-Bowdoin n ...

TL;DR: Data from Next-Generation Sequencing of differential micrococcal nuclease digestions of formaldehyde-crosslinked chromatin in selected tissues of maize (Zea mays) inbred line B73 are presented. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 3, 2018

2017 journal article

Genomic Analysis of the DNA Replication Timing Program during Mitotic S Phase in Maize (Zea mays) Root Tips

PLANT CELL, 29(9), 2126–2149.

By: E. Wear n, J. Song, G. Zynda, C. LeBlanc*, T. Lee n, L. Mickelson-Young n, L. Concia n, P. Mulvaney n ...

MeSH headings : Base Sequence; Chromosomes, Plant / genetics; DNA Replication Timing / genetics; DNA Transposable Elements / genetics; Genes, Plant; Genomics; Meristem / cytology; Meristem / genetics; Mitosis / genetics; Models, Genetic; S Phase / genetics; Tandem Repeat Sequences / genetics; Time Factors; Transcription, Genetic; Zea mays / cytology; Zea mays / genetics
TL;DR: A novel adaptation of the “Repli-seq” assay for use in intact root tips of maize (Zea mays) that includes several different cell lineages and present whole-genome replication timing profiles from cells in early, mid, and late S phase of the mitotic cell cycle is reported. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

A flow cytometric method for estimating S-phase duration in plants


By: L. Mickelson-Young n, E. Wear n, P. Mulvaney n, T. Lee n, E. Szymanski n, G. Allen n, L. Hanley-Bowdoin n, W. Thompson n

author keywords: Arabidopsis; barley; EdU; flow cytometry; maize; replication timing; rice; S-phase duration; wheat
MeSH headings : Arabidopsis / cytology; Arabidopsis / growth & development; DNA, Plant / metabolism; Deoxyuridine / analogs & derivatives; Deoxyuridine / metabolism; Flow Cytometry / methods; G1 Phase / physiology; G2 Phase / physiology; Hordeum / cytology; Hordeum / growth & development; Meristem / cytology; Meristem / growth & development; Oryza / cytology; Oryza / growth & development; S Phase / physiology; Triticum / cytology; Triticum / growth & development; Zea mays / cytology; Zea mays / growth & development
TL;DR: This work estimated S-phase duration for several plant species by following EdU-labeled nuclei from G1 to G2 using bivariate flow cytometry, finding that S- phase duration is relatively consistent over a range of genome sizes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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