Works (2)

Updated: July 5th, 2023 15:58

2006 journal article

Peptide aptamers that bind to a geminivirus replication protein interfere with viral replication in plant cells

JOURNAL OF VIROLOGY, 80(12), 5841–5853.

By: L. Lopez-Ochoa n, J. Ramirez-Prado n & L. Hanley-Bowdoin n

MeSH headings : Aptamers, Peptide / pharmacology; DNA, Viral / analysis; Geminiviridae / chemistry; Geminiviridae / drug effects; Geminiviridae / physiology; Peptide Library; Plant Cells; Plant Viruses / drug effects; Plants / virology; Plants, Genetically Modified; Thioredoxins / genetics; Thioredoxins / metabolism; Transfection; Two-Hybrid System Techniques; Viral Proteins / antagonists & inhibitors; Viral Proteins / genetics; Viral Proteins / metabolism; Viral Proteins / physiology; Virus Replication / drug effects
TL;DR: The peptide aptamers characterized in these studies represent new tools for studying AL1 function and can serve as the basis for the development of crops with broad-based resistance to single-stranded DNA viruses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

A novel motif in geminivirus replication proteins interacts with the plant retinoblastoma-related protein

JOURNAL OF VIROLOGY, 78(9), 4817–4826.

By: G. Arguello-Astorga n, L. Lopez-Ochoa n, L. Kong n, B. Orozco n, S. Settlage n & L. Hanley-Bowdoin n

MeSH headings : Amino Acid Motifs; Amino Acid Sequence; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Geminiviridae / metabolism; Geminiviridae / pathogenicity; Solanum lycopersicum / virology; Molecular Sequence Data; Mutation; Plant Diseases / virology; Plant Leaves / virology; Plant Proteins / metabolism; Retinoblastoma Protein / metabolism; Tobacco / virology; Two-Hybrid System Techniques; Viral Proteins / chemistry; Viral Proteins / genetics; Viral Proteins / metabolism; Virus Replication
TL;DR: Results suggest that helix 4 and the conserved leucine residue are part of a pRBR-binding interface in begomovirus replication proteins. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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