Lulu Cai

Works (2)

Updated: July 5th, 2023 15:34

2019 journal article

Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs

SCIENCE ADVANCES, 5(7).

By: J. Wang n, J. Yu n, Y. Zhang n, X. Zhang*, A. Kahkoska *, G. Chen*, Z. Wang *, W. Sun* ...

MeSH headings : Animals; Blood Glucose / drug effects; Diabetes Mellitus, Experimental / drug therapy; Drug Carriers / chemical synthesis; Drug Carriers / chemistry; Drug Delivery Systems; Insulin / administration & dosage; Mice; Molecular Structure; Polymers / chemical synthesis; Polymers / chemistry; Swine
topics (OpenAlex): Advanced Drug Delivery Systems; Pancreatic function and diabetes; RNA Interference and Gene Delivery
TL;DR: A new strategy to form a micro-sized complex between a charge-switchable polymer with a glucose-sensing moiety and insulin driven by electrostatic interaction achieves high insulin loading efficiency and loading capacity and promotes release under hyperglycemic conditions. (via Semantic Scholar)
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Source: Web Of Science
Added: August 19, 2019

2018 review

Advances in glycosylation-mediated cancer-targeted drug delivery

[Review of ]. DRUG DISCOVERY TODAY, 23(5), 1126–1138.

By: L. Cai n, Z. Gu *, J. Zhong *, D. Wen n, G. Chen n, L. He *, J. Wu *, Z. Gu n

MeSH headings : Animals; Drug Delivery Systems; Glycosylation; Humans; Neoplasms / drug therapy
topics (OpenAlex): Glycosylation and Glycoproteins Research; Cancer Research and Treatments; RNA Interference and Gene Delivery
TL;DR: This review surveys a variety of glycosylation-mediated cancer-targeted drug nanocarriers as well as their applications for cancer therapy and discusses their challenges, opportunities, and future perspectives. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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