Lulu Cai

Works (2)

Updated: July 5th, 2023 15:34

2019 journal article

Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs

SCIENCE ADVANCES, 5(7).

By: J. Wang n, J. Yu n, Y. Zhang n, X. Zhang*, A. Kahkoska *, G. Chen*, Z. Wang *, W. Sun* ...

MeSH headings : Animals; Blood Glucose / drug effects; Diabetes Mellitus, Experimental / drug therapy; Drug Carriers / chemical synthesis; Drug Carriers / chemistry; Drug Delivery Systems; Insulin / administration & dosage; Mice; Molecular Structure; Polymers / chemical synthesis; Polymers / chemistry; Swine
TL;DR: A new strategy to form a micro-sized complex between a charge-switchable polymer with a glucose-sensing moiety and insulin driven by electrostatic interaction achieves high insulin loading efficiency and loading capacity and promotes release under hyperglycemic conditions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 19, 2019

2018 review

Advances in glycosylation-mediated cancer-targeted drug delivery

[Review of ]. DRUG DISCOVERY TODAY, 23(5), 1126–1138.

By: L. Cai n, Z. Gu *, J. Zhong *, D. Wen n, G. Chen n, L. He *, J. Wu *, Z. Gu n

MeSH headings : Animals; Drug Delivery Systems; Glycosylation; Humans; Neoplasms / drug therapy
TL;DR: This review surveys a variety of glycosylation-mediated cancer-targeted drug nanocarriers as well as their applications for cancer therapy and discusses their challenges, opportunities, and future perspectives. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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