Lindsay Nichols
College of Sciences
Works (2)
Updated: July 5th, 2023 14:41
2020 journal article
An artificial pathway for polyketide biosynthesis
Nature Catalysis, 3(7), 536–538.
TL;DR:
Some of the inefficiencies and limitations of these systems have been solved by designing an artificial pathway for carbon–carbon bond formation via iterative rounds of non-decarboxylative thio-Claisen reactions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 3, 2020
2020 journal article
Synthetic biology enabling access to designer polyketides
Current Opinion in Chemical Biology, 58, 45–53.
author keywords: Polyketides; Synthetic biology; Metabolic engineering; Enzyme engineering; Natural products
MeSH headings : Genetic Engineering; Multigene Family; Polyketides / chemistry; Polyketides / metabolism; Synthetic Biology / methods
TL;DR:
Recent successes in gene cluster discovery, host strain engineering, precursor-directed biosynthesis, combinatorial biosynthesis), polyketide tailoring, and high-throughput synthetic biology are discussed, as well as challenges and outlooks for rapidly generating useful target polyketides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: December 22, 2020
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