@article{gayen_nichols_williams_2020, title={An artificial pathway for polyketide biosynthesis}, volume={3}, ISSN={2520-1158}, url={http://dx.doi.org/10.1038/s41929-020-0483-4}, DOI={10.1038/s41929-020-0483-4}, number={7}, journal={Nature Catalysis}, publisher={Springer Science and Business Media LLC}, author={Gayen, Anuran K. and Nichols, Lindsay and Williams, Gavin J.}, year={2020}, month={Jul}, pages={536–538} }
 @article{malico_nichols_williams_2020, title={Synthetic biology enabling access to designer polyketides}, volume={58}, ISSN={1367-5931}, url={http://dx.doi.org/10.1016/j.cbpa.2020.06.003}, DOI={10.1016/j.cbpa.2020.06.003}, abstractNote={The full potential of polyketide discovery has yet to be reached owing to a lack of suitable technologies and knowledge required to advance engineering of polyketide biosynthesis. Recent investigations on the discovery, enhancement, and non-natural use of these biosynthetic gene clusters via computational biology, metabolic engineering, structural biology, and enzymology-guided approaches have facilitated improved access to designer polyketides. Here, we discuss recent successes in gene cluster discovery, host strain engineering, precursor-directed biosynthesis, combinatorial biosynthesis, polyketide tailoring, and high-throughput synthetic biology, as well as challenges and outlooks for rapidly generating useful target polyketides.}, journal={Current Opinion in Chemical Biology}, publisher={Elsevier BV}, author={Malico, Alexandra A. and Nichols, Lindsay and Williams, Gavin J.}, year={2020}, month={Oct}, pages={45–53} }