Lauren E. Bain

Works (5)

Updated: July 5th, 2023 15:43

2015 journal article

Neurotypic cell attachment and growth on III-nitride lateral polarity structures

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 58, 1194–1198.

By: L. Bain n, R. Kirste n, C. Johnson  n, H. Ghashghaei  n, R. Collazo n  & A. Ivanisevic n

author keywords: Gallium nitride; Cell adhesion; Neurons; Semiconductor; Polarity
MeSH headings : Aluminum Compounds / chemistry; Aluminum Compounds / pharmacology; Animals; Cell Adhesion / drug effects; Cell Differentiation / drug effects; Gallium / chemistry; Gallium / pharmacology; Neurons / cytology; Neurons / drug effects; PC12 Cells; Rats; Semiconductors
TL;DR: The designed material configuration is further explored for biochemical sensing, and the lateral polarity scheme may provide a route in assessing the non-specific protein adsorption to this varying nano-topography that drives the subsequent cell response. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Adsorption and adhesion of common serum proteins to nanotextured gallium nitride

NANOSCALE, 7(6), 2360–2365.

By: L. Bain n, M. Hoffmann n, I. Bryan n, R. Collazo n  & A. Ivanisevic n

MeSH headings : Adsorption; Biocompatible Materials / chemistry; Blood Proteins / chemistry; Cell Adhesion / drug effects; Fibrinogen / chemistry; Gallium / chemistry; Humans; Immunoglobulin G / chemistry; Metal Nanoparticles / chemistry; Microscopy, Atomic Force; Molecular Conformation; Nanotechnology / methods; Protein Binding; Reproducibility of Results; Serum Albumin / chemistry; Surface Properties
TL;DR: Interactions between common serum proteins - serum albumin, fibrinogen, and immunoglobulin G - and a nanotextured gallium nitride surface are explored and an assessment of the role of surface texture in dictating protein-surface interactions is provided. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 review

Engineering the Cell-Semiconductor Interface: A Materials Modification Approach using II-VI and III-V Semiconductor Materials

[Review of ]. SMALL, 11(7), 768–780.

By: L. Bain n & A. Ivanisevic n

TL;DR: This review discusses experiments involving unmodified II-VI and III-V semiconductors - a starting point for assessing cytotoxicity and biocompatibility - followed by specific surface modification, including the generation of submicron roughness or the potential effect of quantum dot structures. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Surface topography and chemistry shape cellular behavior on wide band-gap semiconductors

Acta Biomaterialia, 10(6), 2455–2462.

By: L. Bain n, R. Collazo n , S. Hsu*, N. Latham, M. Manfra * & A. Ivanisevic n

author keywords: Gallium nitride; Rat pheochromocytoma (PC12) cells; Surface topography; Surface chemistry; Cell differentiation
MeSH headings : Animals; Cell Adhesion; Microscopy, Electron, Scanning; PC12 Cells; Rats; Semiconductors; Surface Properties
TL;DR: The dependence of cell behavior on both the topographic morphology and surface chemistry is demonstrated, providing further evidence for the importance of surface modification for modulating bio-inorganic interfaces. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2013 journal article

Biomolecular Gradients via Semiconductor Gradients: Characterization of Amino Acid Adsorption to InxGa1–xN Surfaces

ACS Applied Materials & Interfaces, 5(15), 7236–7243.

By: L. Bain n, S. Jewett*, A. Mukund, S. Bedair*, T. Paskova* & A. Ivanisevic*

author keywords: III-V semiconductor; indium gallium nitride; X-ray photoelectron spectroscopy; surface gradient; amino acid; atomic force microscopy
MeSH headings : Adsorption; Amino Acids / chemistry; Arginine / chemistry; Biocompatible Materials / chemistry; Gallium / chemistry; Humans; Indium / chemistry; Microscopy, Atomic Force / methods; Oxides / chemistry; Photochemistry / methods; Photoelectron Spectroscopy / methods; Semiconductors; Spectrophotometry, Ultraviolet / methods; Spectroscopy, Near-Infrared / methods; Static Electricity; Surface Properties
TL;DR: A gradient inorganic substrate featuring varying affinity for amino acid adhesion is presented, which can be applied in generating gradient architectures for biosensors and studying cellular behaviors without application of specialized patterning processes. (via Semantic Scholar)
Sources: Web Of Science, Crossref
Added: August 6, 2018

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