Laura Elizabeth Griffin

Works (11)

Updated: August 24th, 2023 10:30
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2023 journal article

Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro & beta;-Cell Functions Critical for Metabolic Health

Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro & beta;-Cell Functions Critical for Metabolic Health. METABOLITES, 13(7).

By: E. Krueger *, L. Griffin n, J. Beales*, T. Lloyd*, N. Brown *, W. Elison *, C. Kay n , A. Neilson n , J. Tessem *

author keywords: gut microbiome; phytochemicals; flavanol metabolites; glucose sensitivity; responder analysis; personalized nutrition
Sources: Web Of Science, ORCID
Added: August 14, 2023

2022 journal article

Microbial Metabolites of Flavanols in Urine are Associated with Enhanced Anti-Proliferative Activity in Bladder Cancer Cells In Vitro

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 74(1), 194–210.

By: L. Griffin n, S. Kohrt *, A. Rathore n, C. Kay n , M. Grabowska * & A. Neilson n 

MeSH headings : Animals; Chromatography, Liquid; Gastrointestinal Microbiome; Polyphenols / analysis; Rats; Tandem Mass Spectrometry; Urinary Bladder Neoplasms / drug therapy
Sources: Web Of Science, ORCID
Added: February 10, 2021

2021 journal article

Diet-induced obesity in genetically diverse collaborative cross mouse founder strains reveals diverse phenotype response and amelioration by quercetin treatment in 129S1/SvImJ, PWK/EiJ, CAST/PhJ, and WSB/EiJ mice

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 87.

By: L. Griffin n, L. Essenmacher*, K. Racine n, L. Iglesias-Carres  n, J. Tessem *, S. Smith *, A. Neilson n 

author keywords: Natural products; Genetic diversity; Diabetes; Flavonoids; Personalized nutrition; Interindividual variation
MeSH headings : Animals; Anti-Obesity Agents / therapeutic use; Collaborative Cross Mice / genetics; Collaborative Cross Mice / physiology; Diet, High-Fat / adverse effects; Disease Models, Animal; Female; Genetic Variation; Male; Obesity / drug therapy; Obesity / etiology; Obesity / genetics; Quercetin / therapeutic use; Sex Factors
Source: Web Of Science
Added: January 11, 2021

2021 journal article

Fasting and postprandial trimethylamine N-oxide in sedentary and endurance-trained males following a short-term high-fat diet

PHYSIOLOGICAL REPORTS, 9(16).

By: C. Steele *, M. Baugh *, L. Griffin n, A. Neilson n , B. Davy *, M. Hulver*, K. Davy*

author keywords: endurance-trained; high-fat diet; sedentary; trimethylamine N-oxide
MeSH headings : Adolescent; Adult; Cardiometabolic Risk Factors; Diet, High-Fat / adverse effects; Dietary Fats / metabolism; Endurance Training; Fasting / metabolism; Humans; Male; Methylamines / blood; Postprandial Period; Sedentary Behavior
Source: Web Of Science
Added: September 7, 2021

2020 journal article

Modulating Phenolic Bioaccessibility and Glycemic Response of Starch-Based Foods in Wistar Rats by Physical Complexation between Starch and Phenolic Acid

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68(46), 13257–13266.

By: M. Li n, L. Griffin n, S. Corbin n, A. Neilson n  & M. Ferruzzi n

author keywords: LC-MS; in vitro bioaccessibility; cellular uptake efficiency; postprandial glycemic response; Caco-2 human intestinal cells; starch-phenolic complexes
MeSH headings : Animals; Blood Glucose / metabolism; Caco-2 Cells; Glycemic Index; Humans; Hydroxybenzoates / metabolism; Intestines; Male; Phenols / metabolism; Rats; Rats, Wistar; Solanum tuberosum / metabolism; Starch / analysis; Starch / metabolism; Zea mays / metabolism
Source: Web Of Science
Added: January 4, 2021

2020 journal article

Preference for and sensitivity to flavanol mean degree of polymerization in model wines is correlated with body composition

APPETITE, 144.

By: L. Griffin n, C. Diako *, L. Miller *, A. Neilson n , C. Ross * & A. Stewart* 

author keywords: Astringency; Preference; BMI; Body fat percentage; PROP
MeSH headings : Adipose Tissue; Adult; Body Composition / physiology; Body Mass Index; Body Weight / physiology; Female; Food Preferences / drug effects; Food Preferences / physiology; Humans; Male; Middle Aged; Polymerization; Polyphenols / administration & dosage; Propylthiouracil / administration & dosage; Taste / drug effects; Taste / physiology; Taste Buds / drug effects; Taste Threshold / drug effects; Wine / analysis; Young Adult
Sources: Web Of Science, ORCID
Added: December 9, 2019

2020 article

Supplemental treatment options for diabetes: how flavanol metabolites improve beta-cell function

Lloyd, T., Griffin, L., Krueger, E., Beales, J., Barlow, A., Sheets, J., … Tessem, J. (2020, April). FASEB JOURNAL, Vol. 34.

By: T. Lloyd*, L. Griffin n, E. Krueger *, J. Beales*, A. Barlow*, J. Sheets*, I. Ekpo*, M. Ross* ...

Sources: Web Of Science, ORCID
Added: October 12, 2020

2019 journal article

A Mediterranean diet does not alter plasma trimethylamine N-oxide concentrations in healthy adults at risk for colon cancer

FOOD & FUNCTION, 10(4), 2138–2147.

By: L. Griffin*, Z. Djuric *, C. Angiletta*, C. Mitchell *, M. Baugh *, K. Davy*, A. Neilson* 

MeSH headings : Adult; Aged; Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; Bacteria / metabolism; Betaine / blood; Choline / blood; Colonic Neoplasms / blood; Colonic Neoplasms / diet therapy; Colonic Neoplasms / metabolism; Colonic Neoplasms / microbiology; Diet, Mediterranean; Fasting; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines / blood; Middle Aged
Source: Web Of Science
Added: April 20, 2020

2019 journal article

Comparison of Common Analytical Methods for the Quantification of Total Polyphenols and Flavanols in Fruit Juices and Ciders

JOURNAL OF FOOD SCIENCE, 84(8), 2147–2158.

By: S. Ma*, C. Kim*, A. Neilson n , L. Griffin n, G. Peck *, . Sean F. O'Keefe*, A. Stewart* 

author keywords: BSA precipitation; DMAC; flavanols; Folin-Ciocalteu; Lowenthal permanganate titration
MeSH headings : Flavanones / analysis; Food Analysis / methods; Fruit / chemistry; Fruit and Vegetable Juices / analysis; Malus / chemistry; Polyphenols / analysis
Sources: Web Of Science, ORCID
Added: August 5, 2019

2019 journal article

Flavanol Polymerization Is a Superior Predictor of alpha-Glucosidase Inhibitory Activity Compared to Flavanol or Total Polyphenol Concentrations in Cocoas Prepared by Variations in Controlled Fermentation and Roasting of the Same Raw Cocoa Beans

ANTIOXIDANTS, 8(12).

By: K. Racine*, B. Wiersema *, L. Griffin n, L. Essenmacher*, A. Lee *, H. Hopfer *, J. Lambert *, A. Stewart *, A. Neilson n 

author keywords: flavan-3-ol; procyanidin; alpha-glucosidase; melanoidin; Maillard reaction
Source: Web Of Science
Added: January 27, 2020

2019 journal article

Flavanol supplementation protects against obesity-associated increases in systemic interleukin-6 levels without inhibiting body mass gain in mice fed a high-fat diet

NUTRITION RESEARCH, 66, 32–47.

By: L. Griffin*, D. Fausnacht *, J. Tuzo*, A. Addington *, K. Racine*, H. Zhang *, M. Hughes *, K. England* ...

author keywords: Mean degree of polymerization (mDP); Flavanols; Procyanidins (PCs); Glucose intolerance; Cytokines
MeSH headings : Adipose Tissue / chemistry; Animals; Body Composition / drug effects; Diet, High-Fat / adverse effects; Dietary Supplements; Eating / drug effects; Flavonols / administration & dosage; Glucose Intolerance / prevention & control; Grape Seed Extract / chemistry; Inflammation / prevention & control; Insulin Resistance; Interleukin-6 / analysis; Male; Mice; Mice, Inbred C57BL; Obesity / physiopathology; Pinus / chemistry; Plant Bark / chemistry; Weight Gain / drug effects
Source: Web Of Science
Added: July 22, 2019