Laura H. Duncan

Works (6)

Updated: July 5th, 2023 15:50

2020 journal article

Heat shock proteins and small nucleolar RNAs are dysregulated in a Drosophila model for feline hypertrophic cardiomyopathy

G3-GENES GENOMES GENETICS, 11(1).

By: C. Tallo n, L. Duncan n, A. Yamamoto n, J. Slaydon n, G. Arya n, L. Turlapati n, T. Mackay*, M. Carbone n

author keywords: MYBPC3; cMyBP-C; Drosophila melanogaster; feline HCM; hypertrophic cardiomyopathy
MeSH headings : Animals; Cardiomyopathy, Hypertrophic / genetics; Carrier Proteins / genetics; Cats; Disease Models, Animal; Drosophila; Drosophila melanogaster; Female; Heat-Shock Proteins / genetics; Mutation; RNA, Small Nucleolar / genetics
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Source: Web Of Science
Added: June 10, 2021

2009 journal article

Alcohol Sensitivity in Drosophila: Translational Potential of Systems Genetics

GENETICS, 183(2), 733–745.

By: T. Morozova*, J. Ayroles*, K. Jordan*, L. Duncan*, M. Carbone*, R. Lyman*, E. Stone  n, D. Govindaraju ...

MeSH headings : Alcohol Drinking / genetics; Animals; Cluster Analysis; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / genetics; Ethanol / pharmacology; Female; Gene Expression Regulation / drug effects; Gene Regulatory Networks; Genes, Insect / genetics; Genetic Variation; Genome, Insect / genetics; Genome-Wide Association Study / methods; Genotype; Humans; Inbreeding; Malate Dehydrogenase / genetics; Malate Dehydrogenase / metabolism; Male; Phenotype; Polymorphism, Single Nucleotide; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction
TL;DR: Seven intronic single nucleotide polymorphisms of the Malic Enzyme 1 (ME1) gene that are associated with cocktail drinking in 1687 individuals of the Framingham Offspring cohort are identified, implicating that variation in levels of cytoplasmic malic enzyme may contribute to variation in alcohol consumption. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Systems genetics of complex traits in Drosophila melanogaster

NATURE GENETICS, 41(3), 299–307.

By: J. Ayroles n, M. Carbone n, E. Stone  n, K. Jordan n, R. Lyman n, M. Magwire n, S. Rollmann n, L. Duncan n ...

MeSH headings : Amino Acid Sequence; Animals; Animals, Inbred Strains; Base Sequence; Chromosome Mapping; Drosophila melanogaster / genetics; Female; Gene Regulatory Networks / physiology; Genetic Variation / physiology; Genetics, Population / methods; Male; Molecular Sequence Data; Phenotype; Quantitative Trait, Heritable; RNA, Messenger / analysis; RNA, Messenger / genetics; RNA, Messenger / metabolism; Sequence Homology, Amino Acid; Tissue Distribution
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15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

journal article

Epistasis dominates the genetic architecture of Drosophila quantitative traits

Huang, W., Richards, S., Carbone, M. A., Zhu, D. H., Anholt, R. R. H., Ayroles, J. F., … Muzny, D. Proceedings of the National Academy of Sciences of the United States of America, 109(39), 15553–15559.

By: W. Huang, S. Richards, M. Carbone, D. Zhu, R. Anholt, J. Ayroles, L. Duncan, K. Jordan ...

Source: NC State University Libraries
Added: August 6, 2018

journal article

The Drosophila melanogaster genetic reference panel

Mackay, T. F. C., Richards, S., Stone, E. A., Barbadilla, A., Ayroles, J. F., Zhu, D. H., … Carbone, M. A. Nature, 482(7384), 173–178.

By: T. Mackay, S. Richards, E. Stone, A. Barbadilla, J. Ayroles, D. Zhu, S. Casillas, Y. Han ...

Source: NC State University Libraries
Added: August 6, 2018

journal article

The genomic basis of postponed senescence in Drosophila melanogaster

Carnes, M. U., Campbell, T., Huang, W., Butler, D. G., Carbone, M. A., Duncan, L. H., … Mackay, T. F. C. PLoS One, 10(9).

By: M. Carnes, T. Campbell, W. Huang, D. Butler, M. Carbone, L. Duncan, S. Harbajan, E. King ...

Source: NC State University Libraries
Added: August 6, 2018

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