@article{harbison_kumar_huang_mccoy_smith_mackay_2019, title={Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster}, volume={49}, ISSN={["1573-3297"]}, DOI={10.1007/s10519-018-9932-0}, abstractNote={Circadian rhythms influence physiological processes from sleep-wake cycles to body temperature and are controlled by highly conserved cycling molecules. Although the mechanistic basis of the circadian clock has been known for decades, the extent to which circadian rhythms vary in nature and the underlying genetic basis for that variation is not well understood. We measured circadian period (Ʈ) and rhythmicity index in the Drosophila Genetic Reference Panel (DGRP) and observed extensive genetic variation in both. Seven DGRP lines had sexually dimorphic arrhythmicity and one line had an exceptionally long Ʈ. Genome-wide analyses identified 584 polymorphisms in 268 genes. We observed differences among transcripts for nine genes predicted to interact among themselves and canonical clock genes in the long period line and a control. Mutations/RNAi knockdown targeting these genes also affected circadian behavior. Our observations reveal that complex genetic interactions influence high levels of variation in circadian phenotypes.}, number={1}, journal={BEHAVIOR GENETICS}, author={Harbison, Susan T. and Kumar, Shailesh and Huang, Wen and McCoy, Lenovia J. and Smith, Kirklin R. and Mackay, Trudy F. C.}, year={2019}, month={Jan}, pages={60–82} }
 @article{gaertner_ruedi_mccoy_moore_wolfner_mackay, title={Heritable variation in courtship patterns in Drosophila melanogaster}, volume={5}, number={4}, journal={G3-Genes Genomes Genetics}, author={Gaertner, B. E. and Ruedi, E. A. and McCoy, L. J. and Moore, J. M. and Wolfner, M. F. and Mackay, T. F. C.}, pages={531–539} }
 @article{zhou_morozova_hussain_luoma_mccoy_yamamoto_mackay_anholt, title={The genetic basis for variation in sensitivity to lead toxicity in Drosophila melanogaster}, volume={124}, number={7}, journal={Environmental Health Perspectives}, author={Zhou, S. S. and Morozova, T. V. and Hussain, Y. N. and Luoma, S. E. and McCoy, L. and Yamamoto, A. and Mackay, T. F. C. and Anholt, R. R. H.}, pages={1062–1070} }