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Logan James Tisch

College of Sciences

Works (4)

Updated: March 24th, 2025 08:43

2025 journal article

Protease-activated receptor-2 (PAR2) mutation attenuates airway fibrosis in mice during the exacerbation of house dust mite-induced allergic lung disease by multi-walled carbon nanotubes

RESPIRATORY RESEARCH, 26(1).

By: L. Tisch, R. Bartone, S. Antoniak & J. Bonner 

author keywords: Allergens; Nanoparticles; Allergic lung disease; Asthma; PAR2
Sources: Web Of Science, NC State University Libraries
Added: March 17, 2025

2024 article

House Dust Mite Proteins Adsorb on Multiwalled Carbon Nanotubes Forming an Allergen Corona That Intensifies Allergic Lung Disease in Mice

Bartone, R. D., Tisch, L. J., Dominguez, J., Payne, C. K., & Bonner, J. C. (2024, September 11). ACS NANO, Vol. 9.

By: R. Bartone n, L. Tisch n, J. Dominguez *, C. Payne * & J. Bonner n 

author keywords: carbon nanotubes; allergens; biocorona; lung; asthma
topics (OpenAlex): Exercise and Physiological Responses; Allergic Rhinitis and Sensitization; thermodynamics and calorimetric analyses
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 23, 2024

2023 article

House dust mite extract forms a der p 2 corona on multi-walled carbon nanotubes: implications for allergic airway disease

Dominguez, J., Holmes, S. K., Bartone, R. D., Tisch, L. J., Tighe, R. M., Bonner, J. C., & Payne, C. K. (2023, December 15). ENVIRONMENTAL SCIENCE-NANO, Vol. 12.

By: J. Dominguez *, S. Holmes*, R. Bartone n, L. Tisch n, R. Tighe *, J. Bonner n , C. Payne *

topics (OpenAlex): Inhalation and Respiratory Drug Delivery; Air Quality and Health Impacts; Indoor Air Quality and Microbial Exposure
TL;DR: It is found that the corona is dominated by der p 2, a protein associated with human allergic responses to house dust mites, which remains adsorbed on the surface of the MWCNTs following subsequent exposures to lung fluid proteins. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 2, 2024

2023 journal article

Role of the protease-activated receptor-2 (PAR2) in the exacerbation of house dust mite-induced murine allergic lung disease by multi-walled carbon nanotubes

PARTICLE AND FIBRE TOXICOLOGY, 20(1).

By: H. Lee n, D. You n, A. Taylor-Just n, L. Tisch n, R. Bartone n, H. Atkins n, L. Ralph*, S. Antoniak *, J. Bonner n 

author keywords: Carbon nanotubes; Allergens; Protease-activated receptor 2; Lung; Inflammation; Fibrosis
topics (OpenAlex): Blood Coagulation and Thrombosis Mechanisms; Asthma and respiratory diseases; Neonatal Respiratory Health Research
TL;DR: This study indicates that protease-activated receptor 2 (PAR2) mediates airway fibrosis but not eosinophilic lung inflammation induced by co-exposure to MWCNTs and HDM allergens. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 28, 2023

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