Works (5)

Updated: July 5th, 2023 15:40

2020 journal article

Three-dimensional imaging of intact porcine cochlea using tissue clearing and custom-built light-sheet microscopy


By: A. Moatti n, Y. Cai n, C. Li n, T. Sattler n, L. Edwards n, J. Piedrahita n, F. Ligler n, A. Greenbaum n

Sources: Web Of Science, ORCID
Added: December 11, 2020

2018 journal article

Mast cells exert anti-inflammatory effects in an IL10(-/-) model of spontaneous colitis

Mediators of Inflammation.

By: E. Lennon, L. Borst, L. Edwards & A. Moeser

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Early weaning stress induces chronic functional diarrhea, intestinal barrier defects, and increased mast cell activity in a porcine model of early life adversity


By: C. Pohl*, J. Medland n, E. Mackey n, L. Edwards n, K. Bagley n, M. DeWilde*, K. Williams*, A. Moeser*

author keywords: developmental origins of health and disease; early life adversity; intestinal permeability; large animal model; mast cell; mast cell plexitis; translational research
MeSH headings : Animals; Cell Count; Colon / pathology; Diarrhea / etiology; Disease Models, Animal; Enteric Nervous System / pathology; Female; Ileum / metabolism; Ileum / pathology; Intestinal Mucosa / metabolism; Intestinal Mucosa / pathology; Intestinal Mucosa / physiopathology; Intestines / pathology; Intestines / physiopathology; Male; Mast Cells / metabolism; Mast Cells / physiology; Stress, Psychological / complications; Sus scrofa; Tryptases / metabolism; Weaning
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Early life adversity in piglets induces long-term upregulation of the enteric cholinergic nervous system and heightened, sex-specific secretomotor neuron responses


By: J. Medland n, C. Pohl*, L. Edwards n, S. Frandsen n, K. Bagley n, Y. Li*, A. Moeser*

author keywords: cholinergic neurons; early life adversity; enteric nervous system development; irritable bowel syndrome; porcine model
MeSH headings : Animals; Cholinergic Neurons / metabolism; Disease Models, Animal; Enteric Nervous System / metabolism; Female; Irritable Bowel Syndrome / metabolism; Male; Motor Neurons / metabolism; Sex Factors; Stress, Psychological / metabolism; Swine; Up-Regulation; Weaning
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Early-life dietary spray-dried plasma influences immunological and intestinal injury responses to later-life Salmonella typhimurium challenge


By: P. Boyer n, . S. D'Costa, L. Edwards n, M. Milloway n, E. Susick n, L. Borst n, S. Thakur n, J. Campbell ...

author keywords: Spray-dried plasma; Early-life nutrition; Salmonella typhimurium; Intestinal inflammation; Mucosal immunity; Intestinal permeability; Weaning
MeSH headings : Animals; Biomarkers / blood; Biomarkers / metabolism; Blood Proteins / administration & dosage; Blood Proteins / therapeutic use; Crosses, Genetic; Cytokines / blood; Cytokines / metabolism; Diet / adverse effects; Diet / veterinary; Energy Intake; Enterocolitis / immunology; Enterocolitis / microbiology; Enterocolitis / prevention & control; Enterocolitis / veterinary; Feces / microbiology; Female; Ileum / immunology; Ileum / metabolism; Ileum / microbiology; Ileum / pathology; Immunity, Mucosal; Immunotherapy / adverse effects; Immunotherapy / veterinary; Intestinal Mucosa / immunology; Intestinal Mucosa / metabolism; Intestinal Mucosa / microbiology; Intestinal Mucosa / pathology; Male; Salmonella Infections, Animal / immunology; Salmonella Infections, Animal / metabolism; Salmonella Infections, Animal / microbiology; Salmonella Infections, Animal / prevention & control; Salmonella typhimurium / growth & development; Salmonella typhimurium / immunology; Salmonella typhimurium / isolation & purification; Sus scrofa; Swine; Swine Diseases / immunology; Swine Diseases / metabolism; Swine Diseases / microbiology; Swine Diseases / prevention & control; Weaning; Weight Gain
Sources: Web Of Science, ORCID
Added: August 6, 2018