Works (3)

Updated: July 5th, 2023 15:38

2022 journal article

Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature

IUCRJ, 9, 610–624.

author keywords: serial femtosecond crystallography; serial synchrotron crystallography; neutron crystallography; XFELs; room temperature; metalloenzymes
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 29, 2022

2017 journal article

Interaction of Azole-Based Environmental Pollutants with the Coelomic Hemoglobin from Amphitrite ornata: A Molecular Basis for Toxicity

Biochemistry, 56(17), 2294–2303.

By: N. McCombs n, T. Moreno-Chicano*, L. Carey n, S. Franzen n, M. Hough* & R. Ghiladi n

Contributors: N. McCombs n, T. Moreno-Chicano*, L. Carey n, S. Franzen n, M. Hough* & R. Ghiladi n

MeSH headings : Amino Acid Motifs; Animals; Benzimidazoles / chemistry; Benzimidazoles / metabolism; Benzimidazoles / toxicity; Catalytic Domain; Computational Biology; Environmental Pollutants / chemistry; Environmental Pollutants / metabolism; Environmental Pollutants / toxicity; Enzyme Inhibitors / chemistry; Enzyme Inhibitors / metabolism; Enzyme Inhibitors / toxicity; Fungicides, Industrial / chemistry; Fungicides, Industrial / metabolism; Fungicides, Industrial / toxicity; Hemoglobins / antagonists & inhibitors; Hemoglobins / chemistry; Hemoglobins / metabolism; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Imidazoles / chemistry; Imidazoles / metabolism; Imidazoles / toxicity; Indazoles / chemistry; Indazoles / metabolism; Indazoles / toxicity; Isoenzymes / antagonists & inhibitors; Isoenzymes / chemistry; Isoenzymes / metabolism; Kinetics; Ligands; Models, Molecular; Peroxidases / antagonists & inhibitors; Peroxidases / chemistry; Peroxidases / metabolism; Pesticides / chemistry; Pesticides / metabolism; Pesticides / toxicity; Polychaeta / enzymology; Recombinant Fusion Proteins / chemistry; Recombinant Fusion Proteins / metabolism; Recombinant Proteins / chemistry; Recombinant Proteins / metabolism; Triazoles / chemistry; Triazoles / metabolism; Triazoles / toxicity
TL;DR: The results demonstrate a new mechanism by which azole pollutants can potentially disrupt hemoglobin function, thereby improving the understanding of their impact on infaunal organisms in marine and aquatic environments. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2016 journal article

Nonmicrobial Nitrophenol Degradation via Peroxygenase Activity of Dehaloperoxidase-Hemoglobin fromAmphitrite ornata

Biochemistry, 55(17), 2465–2478.

By: N. McCombs n, J. D’Antonio n, D. Barrios n, L. Carey n & R. Ghiladi n

Contributors: N. McCombs n, . J. D'Antonio, D. Barrios n, L. Carey n & R. Ghiladi n

MeSH headings : Animals; Catalysis; Hemoglobins / metabolism; Hydrogen Peroxide / metabolism; Mixed Function Oxygenases / metabolism; Nitrophenols; Oxidation-Reduction; Oxygen / metabolism; Peroxidases / metabolism; Polychaeta / enzymology
TL;DR: The results demonstrate that there may be a much larger number of nonmicrobial enzymes that are underrepresented when it comes to understanding the degradation of persistent organic pollutants such as nitrophenols in the environment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

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