Leslie R. Wilson

Works (2)

Updated: July 5th, 2023 15:38

2017 journal article

Selective and Mechanically Robust Sensors for Electrochemical Measurements of Real-Time Hydrogen Peroxide Dynamics in Vivo

Analytical Chemistry, 90(1), 888–895.

By: L. Wilson n, S. Panda  n, A. Schmidt  n & L. Sombers n 

MeSH headings : Animals; Carbon / chemistry; Corpus Striatum / metabolism; Electrochemical Techniques / instrumentation; Electrochemical Techniques / methods; Hydrogen Peroxide / analysis; Male; Microelectrodes; Phenylenediamines / chemistry; Rats, Sprague-Dawley
TL;DR: The data demonstrate that this technology can be used to ensure the selective detection of H2O2, enabling confident characterization of the role this molecule plays in normal physiological function as well as in the progression of PD and other neuropathies involving oxidative stress. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Unmasking the Effects of L-DOPA on Rapid Dopamine Signaling with an Improved Approach for Nafion Coating Carbon-Fiber Microelectrodes

ANALYTICAL CHEMISTRY, 88(16), 8129–8136.

By: L. Qi n, E. Thomas  n, S. White n, S. Smith n, C. Lee n, L. Wilson n, L. Sombers n 

MeSH headings : Animals; Brain / drug effects; Brain / metabolism; Carbon / chemistry; Carbon Fiber; Dopamine / analysis; Electrochemical Techniques; Electrodes, Implanted; Evoked Potentials / drug effects; Levodopa / pharmacology; Male; Microelectrodes; Parkinson Disease / metabolism; Parkinson Disease / pathology; Rats; Rats, Sprague-Dawley; Signal Transduction / drug effects
TL;DR: Overall, this work describes a reliable tool that allows a better measure of L-DOPA augmented dopamine release in vivo, measured using fast-scan cyclic voltammetry. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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