Sharon R Lubkin

Works (76)

Updated: January 23rd, 2026 05:06

2024 article

Morphoelastic models discriminate between different mechanisms of left-right asymmetric stomach morphogenesis

Nikas, A. N., Curcio, E. J., Nascone-Yoder, N., & Lubkin, S. R. (2024, January 26). Cells and Development, Vol. 177.

By: A. Nikas  n, E. Curcio  n, N. Nascone-Yoder n  & S. Lubkin n 

author keywords: Stomach morphogenesis; Morphoelasticity; Modeling; left/right asymmetry
MeSH headings : Animals; Body Patterning / genetics; Morphogenesis; Vertebrates; Stomach; Signal Transduction
topics (OpenAlex): Congenital heart defects research; Developmental Biology and Gene Regulation; Morphological variations and asymmetry
TL;DR: A continuum model of asymmetric stomach morphogenesis is developed using a morphoelastic framework and reveals that, of the various differential growth mechanisms tested, only one category is consistent with the leftward stomach curvature observed in wild-type embryos. (via Semantic Scholar)
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Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 28, 2024

2024 article

Towards a Mathematical Understanding of Ventilator-Induced Lung Injury in Preterm Rat Pups

Luke, R. A., Kelly, G., Stoner, M., Jordana, E. O. B., Lubkin, S. R., & Fix, L. E. (2024, January 1). ˜The œIMA Volumes in Mathematics and Its Applications.

By: R. Luke*, G. Kelly*, M. Stoner*, E. Jordana*, S. Lubkin n  & L. Fix *

topics (OpenAlex): Neonatal Respiratory Health Research; Congenital Diaphragmatic Hernia Studies; Preterm Birth and Chorioamnionitis
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Source: ORCID
Added: January 22, 2026

2023 article

Flexural rigidity of pressurized model notochords in regular packing patterns

Curcio, E. J., & Lubkin, S. R. (2023, November 30). Cells and Development.

By: E. Curcio  n & S. Lubkin n 

MeSH headings : Notochord; Biomechanical Phenomena
topics (OpenAlex): Cellular Mechanics and Interactions; Microtubule and mitosis dynamics; Micro and Nano Robotics
TL;DR: The eccentric staircase pattern of cell packing has more than double the flexural rigidity of the radially symmetric bamboo pattern and is found to be more than twice as stiff in lateral bending than in dorsoventral bending, suggesting a mechanical advantage to the eccentric WT staircase patterns of the embryonic notochord. (via Semantic Scholar)
Source: ORCID
Added: January 28, 2024

2023 article

Physical models of notochord cell packing reveal how tension ratios determine morphometry

Curcio, E. J., & Lubkin, S. R. (2023, January 25). Cells and Development, Vol. 173.

By: E. Curcio n & S. Lubkin n 

author keywords: Notochord; Foams; Biomechanics; Cell packing; Sheath tension; Modeling
MeSH headings : Notochord / physiology; Body Weights and Measures
topics (OpenAlex): Cellular Mechanics and Interactions; Microtubule and mitosis dynamics; Cellular transport and secretion
TL;DR: Observations on the relationship between mechanics, geometry, and pattern provide a framework for further work which may provide insight into the roles of mechanosensing and pressure-volume regulation in the notochord. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: February 27, 2023

2021 article

Bubble packing, eccentricity, and notochord development

Sorrell, E. L., & Lubkin, S. R. (2021, October 30). Cells and Development, Vol. 3.

By: E. Sorrell n & S. Lubkin n 

author keywords: Notochord; Foam; Biomechanics; Packing pattern; Tissue mechanics
MeSH headings : Embryonic Development; Notochord
topics (OpenAlex): Advanced Materials and Mechanics; Micro and Nano Robotics; Microtubule and mitosis dynamics
TL;DR: The eccentricity of staircase patterns in flexible and semi-flexible tubes is found to be dependent on the tension ratio Γ, increasing as sheath tension decreases relative to interior cell tension. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: July 18, 2022

2019 article

Does viral load alter behavior of the bee parasite Varroa destructor?

Giuffre, C., Lubkin, S. R., & Tarpy, D. R. (2019, June 13). (O. Rueppell, Ed.). PLoS ONE, Vol. 14, p. e0217975.

By: C. Giuffre*, S. Lubkin n  & D. Tarpy n 

Ed(s): O. Rueppell

MeSH headings : Animals; Arachnid Vectors / virology; Bees / parasitology; Behavior, Animal; Host-Pathogen Interactions; RNA Viruses / isolation & purification; Real-Time Polymerase Chain Reaction; Varroidae / virology; Viral Load
topics (OpenAlex): Insect and Pesticide Research; Plant and animal studies; Insect and Arachnid Ecology and Behavior
TL;DR: Statistically significant models reveal that colony, DWV, and SBV all might play a role in mite behavior, suggesting that the varroa-virus interaction needs to be an integral part of future studies on honey bee pathogens. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 1, 2019

2018 article

Tissue geometry may govern lung branching mode selection

George, U. Z., & Lubkin, S. R. (2018, January 9). Journal of Theoretical Biology, Vol. 442, pp. 22–30.

By: U. George * & S. Lubkin n 

MeSH headings : Animals; Cell Proliferation; Fibroblast Growth Factor 10 / metabolism; Humans; Lung / anatomy & histology; Lung / embryology; Lung / metabolism; Mesoderm / cytology; Mesoderm / embryology; Mesoderm / metabolism; Mice; Models, Anatomic; Morphogenesis
topics (OpenAlex): Cancer Cells and Metastasis; Fibroblast Growth Factor Research
TL;DR: A computational model of the epithelial lung bud and its surrounding mesenchyme is developed and it is found that a single simple mechanism is theoretically capable of directing an epithelial tubule to elongate, bend, flatten, or bifurcate, depending solely on geometric ratios of the tissues in the vicinity of a growing tubule tip. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2018 article

Tissue self-organization underlies morphogenesis of the notochord

Norman, J., Sorrell, E. L., Hu, Y., Siripurapu, V., Garcia, J., Bagwell, J., … Bagnat, M. (2018, September 24). Philosophical Transactions of the Royal Society B Biological Sciences, Vol. 373, p. 20170320.

By: J. Norman *, E. Sorrell n, Y. Hu *, V. Siripurapu*, J. Garcia *, J. Bagwell *, P. Charbonneau *, S. Lubkin n , M. Bagnat *

author keywords: zebrafish; notochord; vacuolated cells; packing; self-organization
MeSH headings : Animals; Cell Count; Embryonic Development; Models, Biological; Morphogenesis; Notochord / embryology; Zebrafish / embryology
topics (OpenAlex): Cellular Mechanics and Interactions; Microtubule and mitosis dynamics; Caveolin-1 and cellular processes
TL;DR: It is concluded that self-organization underlies morphogenesis of the vertebrate notochord, a conserved axial structure that in vertebrates serves as a hydrostatic scaffold for embryonic axis elongation and, later on, for proper spine assembly. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 16, 2018

2017 article

Automated assay and differential model of western honey bee (Apis mellifera) autogrooming using digital image processing

Giuffre, C., Lubkin, S. R., & Tarpy, D. R. (2017, March 1). Computers and Electronics in Agriculture, Vol. 135, pp. 338–344.

By: C. Giuffre n, S. Lubkin n  & D. Tarpy n 

author keywords: Grooming behavior; Honey bees; Social insects; Image processing
topics (OpenAlex): Insect and Arachnid Ecology and Behavior; Insect and Pesticide Research; Plant and animal studies
TL;DR: A novel, automated honey bee grooming assay was developed and tested to expedite data collection of grooming behavior by testing different honey bee genotypes (stocks), and bees from the different commercial stocks were not significantly different in their grooming rates. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 article

A note on how to develop interdisciplinary collaborations between experimentalists and theoreticians

Madzvamuse, A., & Lubkin, S. R. (2016, August 19). Interface Focus, Vol. 6, p. 20160069.

By: A. Madzvamuse * & S. Lubkin n 

Contributors: A. Madzvamuse * & S. Lubkin n 

author keywords: experimental biology; theoretical biology; biophysics; cell biology
topics (OpenAlex): Cellular Mechanics and Interactions; Biocrusts and Microbial Ecology; Mathematical Biology Tumor Growth; 3D Printing in Biomedical Research; Cell Image Analysis Techniques; Microfluidic and Bio-sensing Technologies
TL;DR: This special issue is inspired by and based on the six-month research programme held at the Isaac Newton Institute for Mathematical Sciences, Cambridge, UK between 13 July and 18 December 2015 entitled ‘Coupling geometric partial differential equations with physics for cell morphology, motility and pattern formation’. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 article

Quantifying cellular and subcellular stretches in embryonic lung epithelia under peristalsis: where to look for mechanosensing

Bokka, K. K., Jesudason, E. C., Warburton, D., & Lubkin, S. R. (2016, August 19). Interface Focus.

By: K. Bokka n, E. Jesudason *, D. Warburton* & S. Lubkin n 

Contributors: K. Bokka n, E. Jesudason *, D. Warburton* & S. Lubkin n 

author keywords: lung; airway; peristalsis; deformation; stenosis; morphogenesis
topics (OpenAlex): Neonatal Respiratory Health Research; Congenital Diaphragmatic Hernia Studies; Spacecraft and Cryogenic Technologies; Connective tissue disorders research; Elasticity and Material Modeling
TL;DR: This work geometrically analyses cell shapes in an epithelial tissue, and individual cell deformations resulting from peristaltic waves that completely occlude the airway, and gives a quantitative estimate of the relationship between length of occluded airway and the resulting tissue stretch in the distal tip. (via Semantic Scholar)
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Added: August 6, 2018

2015 article

Diffusion coefficients (mum2/s) of various molecules in various fluids.

Figshare.

By: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

Contributors: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

topics (OpenAlex):
Source: ORCID
Added: August 23, 2021

2015 article

Morphogenetic Implications of Peristalsis-Driven Fluid Flow in the Embryonic Lung

Bokka, K. K., Jesudason, E. C., Lozoya, O. A., Guilak, F., Warburton, D., & Lubkin, S. R. (2015, July 6). PLoS ONE, Vol. 10.

By: K. Bokka n, E. Jesudason *, O. Lozoya *, F. Guilak *, D. Warburton * & S. Lubkin n 

Contributors: K. Bokka n, E. Jesudason *, O. Lozoya *, F. Guilak *, D. Warburton * & S. Lubkin n 

MeSH headings : Animals; Embryo, Mammalian / embryology; Humans; Lung / embryology; Models, Biological; Organogenesis / physiology
topics (OpenAlex): Aerosol Filtration and Electrostatic Precipitation; Micro and Nano Robotics; Neonatal Respiratory Health Research
TL;DR: The first measurements of the viscosity of embryonic lung lumen fluid are reported, which indicate that if the airway is closed, fluid transport is minimal; by contrast, if the trachea is open, shear rates can be very high, particularly at the stenosis. (via Semantic Scholar)
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Source: ORCID
Added: August 23, 2021

2015 article

Morphogenetic implications of peristaltic fluid–tissue dynamics in the embryonic lung

Bokka, K. K., Jesudason, E. C., Warburton, D., & Lubkin, S. R. (2015, July 10). Journal of Theoretical Biology, Vol. 382, pp. 378–385.

By: K. Bokka n, E. Jesudason *, D. Warburton & S. Lubkin n 

Contributors: K. Bokka n, E. Jesudason *, D. Warburton & S. Lubkin n 

author keywords: Airway; Peristalsis; Fluid-structure interaction; Pressure; Morphogenesis
MeSH headings : Animals; Computer Simulation; Epithelium / physiology; Hydrodynamics; Lung / embryology; Lung / physiology; Models, Biological; Morphogenesis; Peristalsis / physiology; Time Factors
topics (OpenAlex): Fluid Dynamics and Vibration Analysis; Spacecraft and Cryogenic Technologies; Quantum, superfluid, helium dynamics
TL;DR: A model of the fluid-structure interactions between embryonic tissues and lumen fluid resulting from peristaltic waves that partially occlude the airway finds that if theAirway is closed, deformations are synchronized; by contrast, if the trachea is open, maximal occlusion precedes maximal pressure. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 article

Parameters and variables used in estimates and computational model.

Figshare.

By: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

Contributors: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

topics (OpenAlex):
Source: ORCID
Added: August 23, 2021

2015 article

Quantifying stretch and secretion in the embryonic lung: Implications for morphogenesis

George, U. Z., Bokka, K. K., Warburton, D., & Lubkin, S. R. (2015, July 17). Mechanisms of Development, Vol. 138, pp. 356–363.

By: U. George n, K. Bokka n, D. Warburton & S. Lubkin n 

Contributors: U. George n, K. Bokka n, D. Warburton & S. Lubkin n 

author keywords: Morphogenesis; Lung; Mechanics; Transport; Secretion; Mechanobiology
MeSH headings : Animals; Biomechanical Phenomena; Hydrodynamics; Imaging, Three-Dimensional; Lung / embryology; Lung / metabolism; Lung / physiology; Mice; Models, Biological; Morphogenesis / physiology; Rheology; Trachea / embryology; Trachea / physiology
topics (OpenAlex): Neonatal Respiratory Health Research
TL;DR: The results are consistent with the hypothesis that tracheal occlusion blocks outflow of secretions, leading to a higher number of high-flux locations at branching tips, in turn lead to a large increase in number of branching locations. (via Semantic Scholar)
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Added: August 6, 2018

2015 article

S1_File.rar

Figshare.

By: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

Contributors: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

topics (OpenAlex):
Source: ORCID
Added: August 23, 2021

2015 article

S1_Video.avi

Figshare.

By: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

Contributors: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

topics (OpenAlex):
Source: ORCID
Added: August 23, 2021

2015 article

S2_Video.avi

Figshare.

By: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

Contributors: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

topics (OpenAlex):
Source: ORCID
Added: August 23, 2021

2015 article

S3_Video.avi

Figshare.

By: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

Contributors: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

topics (OpenAlex):
Source: ORCID
Added: August 23, 2021

2015 article

S4_Video.avi

Figshare.

By: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

Contributors: K. Bokka, O. Lozoya, S. Lubkin , E. Jesudason, D. Warburton & F. Guilak

topics (OpenAlex):
Source: ORCID
Added: August 23, 2021

2014 article

A Robin-Robin Domain Decomposition Method for a Stokes-Darcy Structure Interaction with a Locally Modified Mesh

Wang, Z., Li, Z., & Lubkin, S. (2014, July 1). Numerical Mathematics Theory Methods and Applications, Vol. 7, pp. 435–446.

By: Z. Wang  n, Z. Li & S. Lubkin 

Contributors: Z. Wang  n, Z. Li & S. Lubkin 

author keywords: Stokes-Darcy fluid structure interactions; Robin-Robin domain decomposition method; body fitted mesh; locally modified mesh; BJS interface condition
topics (OpenAlex): Lattice Boltzmann Simulation Studies; Advanced Numerical Methods in Computational Mathematics; Fluid Dynamics and Vibration Analysis
TL;DR: A new numerical method based on locally modified Cartesian meshes is proposed for solving a coupled system of a fluid flow and a porous media flow using a Robin-Robin domain decomposition method with a Cartesian mesh with local modifications near the interface. (via Semantic Scholar)
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Sources: ORCID, NC State University Libraries
Added: August 23, 2021

2014 journal article

A robin-robin domain decomposition method for a stokes-darcy structure interaction with a locally modified mesh

Numerical Mathematics: Theory, Methods and Applications, 7(4), 435–446.

By: Z. Wang, Z. Li & S. Lubkin 

Source: NC State University Libraries
Added: August 6, 2018

2012 article

An augmented immersed interface method for moving structures with mass

Hao, J., Li, Z., & Lubkin, S. R. (2012, January 1). Discrete and Continuous Dynamical Systems - B, Vol. 17, pp. 1175–1184.

By: J. Hao n, Z. Li*  & S. Lubkin* 

Contributors: J. Ho n, Z. Li*  & S. Lubkin* 

author keywords: Immersed interface method; augmented method; projection method; Navier-Stokes; moving interface; implicit scheme; fluid-structure
topics (OpenAlex): Lattice Boltzmann Simulation Studies; Fluid Dynamics and Vibration Analysis; Fluid Dynamics and Turbulent Flows
TL;DR: An augmented immersed interface method for simulating the dynamics of a deformable structure with mass in an incompressible fluid and shows that the fluid-structure system has bi-stability: a stationary state for a smaller Reynolds number and an oscillatoryState for a larger Reynolds number. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Embryonic Airway Peristalsis: the Mechanical Framework.

Molecular Biology of the Cell, 23. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000209348605105&KeyUID=WOS:000209348605105

By: K. Krishna, E. Jesudason, D. Warburton & S. Lubkin 

Contributors: K. Krishna, E. Jesudason, D. Warburton & S. Lubkin 

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

2011 journal article

Mechanical Control of Epithelial Growth: Distinct Morphogenetic Regimes

Biophysical Journal, 100(3), 444a.

By: O. Lozoya & S. Lubkin* 

Contributors: O. Lozoya & S. Lubkin* 

topics (OpenAlex): Cellular Mechanics and Interactions; 3D Printing in Biomedical Research; Microtubule and mitosis dynamics
TL;DR: A model of transport and growth in epithelio-mesenchymal interactions provides a theoretical basis for explaining epithelial growth arrest despite proteolysis of surrounding tissue, and gives a quantitative framework for the design and interpretation of experiments. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 28, 2020

2011 article

Mechanical control of spheroid growth: Distinct morphogenetic regimes

Lozoya, O. A., & Lubkin, S. R. (2011, December 10). Journal of Biomechanics, Vol. 45, pp. 319–325.

By: O. Lozoya  n & S. Lubkin n 

Contributors: O. Lozoya  n & S. Lubkin n 

author keywords: Mechanics; Growth factor; Protease; Stem cell niche; Embryoid body; Swelling
MeSH headings : Animals; Epithelial-Mesenchymal Transition / physiology; Humans; Models, Biological; Spheroids, Cellular / physiology
topics (OpenAlex): Cellular Mechanics and Interactions; 3D Printing in Biomedical Research; Mathematical Biology Tumor Growth
TL;DR: A model of transport and growth in epithelio-mesenchymal interactions provides a theoretical basis for explaining observations of growth arrest despite proteolysis of surrounding tissue, and gives a quantitative framework for the design and interpretation of experiments involving spheroids, and tissues which are locally equivalent to spheroid. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 article

Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche

Lozoya, O. A., Wauthier, E., Turner, R. A., Barbier, C., Prestwich, G. D., Guilak, F., … Reid, L. M. (2011, July 26). Biomaterials, Vol. 32, pp. 7389–7402.

By: O. Lozoya  n, E. Wauthier n, R. Turner n, C. Barbier n, G. Prestwich*, F. Guilak *, R. Superfine, S. Lubkin n , L. Reid  n

Contributors: O. Lozoya  n, E. Wauthier n, R. Turner n, C. Barbier n, G. Prestwich*, F. Guilak *, R. Superfine, S. Lubkin n , L. Reid  n

author keywords: Maturational lineages; Human hepatic stem cells; Human hepatoblasts; Hyaluronans; Microenvironment mechanical properties; Differentiation
MeSH headings : Cell Differentiation; Cell Survival; Cells, Cultured; Diffusion; Elasticity; Gene Expression; Humans; Hyaluronic Acid / chemistry; Hyaluronic Acid / metabolism; Hydrogels / chemistry; Hydrogels / metabolism; Liver / cytology; Phenotype; Stem Cell Niche; Stem Cells / cytology; Stem Cells / metabolism
topics (OpenAlex): 3D Printing in Biomedical Research; Cellular Mechanics and Interactions; Liver physiology and pathology
TL;DR: This study shows that the mechanical properties of the microenvironment can regulate differentiation in endodermal stem cell populations. (via Semantic Scholar)
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Added: August 6, 2018

2010 article

Lung Organogenesis

Warburton, D., El-Hashash, A., Carraro, G., Tiozzo, C., Sala, F., Rogers, O., … Jesudason, E. (2010, January 1). (P. Koopman, Ed.). Current Topics in Developmental Biology/Current Topics in Developmental Biology, Vol. 90, pp. 73–158.

By: D. Warburton*, A. El-Hashash*, G. Carraro *, C. Tiozzo *, F. Sala *, O. Rogers*, S. Langhe *, P. Kemp * ...

Contributors: D. Warburton*, A. El-Hashash*, G. Carraro *, C. Tiozzo *, F. Sala *, O. Rogers*, S. De Langhe *, P. Kemp * ...

Ed(s): P. Koopman

MeSH headings : Animals; Biomechanical Phenomena; Cell Proliferation; Epithelial Cells / cytology; Epithelial Cells / physiology; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Humans; Intercellular Signaling Peptides and Proteins / genetics; Intercellular Signaling Peptides and Proteins / metabolism; Lung / anatomy & histology; Lung / embryology; Lung / growth & development; MicroRNAs / genetics; MicroRNAs / metabolism; Organogenesis / physiology; Signal Transduction / physiology; Stem Cells / cytology; Stem Cells / physiology; Transcription Factors / genetics; Transcription Factors / metabolism
topics (OpenAlex): Neonatal Respiratory Health Research; Congenital Diaphragmatic Hernia Studies; Congenital heart defects research
TL;DR: It is proposed that looking at the lung in general and branching in particular in terms of clocks may yield unexpected benefits, and efforts to parse the finer detail of lung bud signaling may need to be combined with broader consideration of overarching mechanisms that may be therapeutically easier to target. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Analysis and Computation for a Fluid Mixture Model

Communications in Computational Physics, 5(2-4), 620–634. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000263563600023&KeyUID=WOS:000263563600023

By: Q. Jiang, Z. Li & S. Lubkin 

Contributors: Q. Jiang, Z. Li & S. Lubkin 

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

2009 conference paper

Analysis and computation for a fluid mixture model

Communications in Computational Physics, 5(2-4), 620–634.

By: Q. Jiang, Z. Li  & S. Lubkin 

Source: NC State University Libraries
Added: August 6, 2018

2008 article

Convergent extension by intercalation without mediolaterally fixed cell motion

Backes, T. M., Latterman, R., Small, S. A., Mattis, S., Pauley, G., Reilly, E., & Lubkin, S. R. (2008, September 28). Journal of Theoretical Biology, Vol. 256, pp. 180–186.

By: T. Backes n, R. Latterman n, S. Small n, S. Mattis n, G. Pauley n, E. Reilly n, S. Lubkin n 

Contributors: T. Backes n, R. Latterman n, S. Small n, S. Mattis n, G. Pauley n, E. Reilly n, S. Lubkin n 

author keywords: Convergent extension; Morphogenesis; Intercalation; Stochastic model
MeSH headings : Animals; Cell Adhesion / physiology; Cell Movement / physiology; Cell Shape / physiology; Models, Biological; Morphogenesis / physiology; Stochastic Processes
topics (OpenAlex): Cellular Mechanics and Interactions; 3D Printing in Biomedical Research; Cell Adhesion Molecules Research
TL;DR: A stochastic model of convergent extension of tissue that extends and converges to a stacked arrangement of elongated cells one cell wide, an arrangement which is seen in ascidian notochords, but which has not been observed in other models. (via Semantic Scholar)
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Added: August 6, 2018

2007 article

Branched Organs: Mechanics of Morphogenesis by Multiple Mechanisms

Lubkin, S. R. (2007, December 1). (S. Schnell, P. K. Maini, S. A. Newman, & T. J. Newman, Eds.). Current Topics in Developmental Biology/Current Topics in Developmental Biology, Vol. 81, pp. 249-+.

By: S. Lubkin n 

Contributors: S. Lubkin n 

Ed(s): S. Schnell, P. Maini, S. Newman & T. Newman

MeSH headings : Animals; Apoptosis; Basement Membrane / cytology; Biomechanical Phenomena; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Shape; Cell Size; Extracellular Matrix / physiology; Mesoderm / cytology; Models, Biological; Morphogenesis; Viscosity
topics (OpenAlex): Cellular Mechanics and Interactions; Microtubule and mitosis dynamics; Advanced Materials and Mechanics
TL;DR: Several models of the mechanics of cleft formation are developed and the implications of several candidate mechanisms are discussed and what has been found in models and in experiments are reviewed. (via Semantic Scholar)
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Added: August 6, 2018

2007 article

Mechanics of mesenchymal contribution to clefting force in branching morphogenesis

Wan, X., Li, Z., & Lubkin, S. R. (2007, September 27). Biomechanics and Modeling in Mechanobiology, Vol. 7, pp. 417–426.

By: X. Wan n, Z. Li n  & S. Lubkin n 

Contributors: X. Wan n, Z. Li n  & S. Lubkin n 

MeSH headings : Animals; Computer Simulation; Embryo, Mammalian; Epithelium / physiology; Extracellular Matrix / physiology; Kinetics; Mesoderm / cytology; Mesoderm / physiology; Models, Biological; Morphogenesis / physiology; Stress, Mechanical; Viscosity
topics (OpenAlex): Cellular Mechanics and Interactions; Connective tissue disorders research; Microtubule and mitosis dynamics
TL;DR: A 3D model of the mechanics of clefting is developed, focusing in this paper solely on the potential role of mesenchyme-generated traction forces, and finds that mesenchymal traction forces are sufficient to generate a cleft of the correct size and morphology, in the correct time frame. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2006 journal article

An augmented approach for the pressure boundary condition in a Stokes flow

Communications in Computational Physics, 1(5), 874–885. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000241516600006&KeyUID=WOS:000241516600006

By: Z. Li , X. Wan, K. Ito & S. Lubkin 

Contributors: Z. Li , X. Wan, K. Ito & S. Lubkin 

gateway.webofknowledge.com
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2006 book

Developmental biology: Branching morphogenesis

In Complex Systems Science in BioMedicine (pp. 357–374). http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=BCI&KeyUT=BCI:BCI200700025770&KeyUID=BCI:BCI200700025770

By: S. Lubkin , T. Deisboeck & J. Kresh

Contributors: S. Lubkin , T. Deisboeck & J. Kresh

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

2006 article

Optimizing Detection of Tissue Anisotropy by Fluorescence Recovery after Photobleaching

Lubkin, S. R., & Wan, X. (2006, July 19). Bulletin of Mathematical Biology, Vol. 68, pp. 1873–1891.

By: S. Lubkin n  & X. Wan n

Contributors: S. Lubkin n  & X. Wan n

author keywords: hindered diffusion; anisotropic diffusion; polydisperse; cartilage; fluorescence microscopy
MeSH headings : Anisotropy; Cartilage / chemistry; Cartilage / metabolism; Collagen / chemistry; Computer Simulation; Fluorescence Recovery After Photobleaching / methods; Microscopy, Fluorescence; Models, Biological
topics (OpenAlex): Optical Imaging and Spectroscopy Techniques; Medical Imaging Techniques and Applications; Spaceflight effects on biology
TL;DR: It is concluded that FRAP can be used to detect tissue anisotropy when the tracer molecule is sufficiently large relative to the fiber diameter, volume fraction, and degree of polydispersivity, and when the anisOTropy is sufficiently pronounced. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2006 article

Quantifying the Significance of Phage Attack on Starter Cultures: a Mechanistic Model for Population Dynamics of Phage and Their Hosts Isolated from Fermenting Sauerkraut

Mudgal, P., Breidt, F., Lubkin, S. R., & Sandeep, K. P. (2006, June 1). Applied and Environmental Microbiology, Vol. 72, pp. 3908–3915.

By: P. Mudgal n, F. Breidt n, S. Lubkin n  & K. Sandeep n 

Contributors: P. Mudgal n, F. Breidt n, S. Lubkin n  & K. Sandeep n 

MeSH headings : Bacteria / growth & development; Bacteria / virology; Bacteriophages / growth & development; Bacteriophages / isolation & purification; Brassica / microbiology; Food Handling / methods; Leuconostoc / growth & development; Leuconostoc / isolation & purification; Leuconostoc / virology; Models, Theoretical
topics (OpenAlex): Bacteriophages and microbial interactions; Plant Virus Research Studies; Plant and Fungal Interactions Research
TL;DR: It was suggested that the kinetic parameters of phage-host interaction, especially the adsorption rate, vary with the initial phage and host densities and with time, and the effects of heterogeneity and other environmental factors should be considered to make the model applicable to commercial fermentations. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2006 article

Semi-mechanistic Partial Buffer Approach to Modeling pH, the Buffer Properties, and the Distribution of Ionic Species in Complex Solutions

Dougherty, D. P., Neta, E. R. D. C., McFeeters, R. F., Lubkin, S. R., & Breidt, F. (2006, July 15). Journal of Agricultural and Food Chemistry, Vol. 54, pp. 6021–6029.

By: D. Dougherty  n, E. Neta n, R. McFeeters n, S. Lubkin n  & F. Breidt n

Contributors: D. Dougherty  n, E. Neta n, R. McFeeters n, S. Lubkin n  & F. Breidt n

author keywords: buffer capacity; Cucumis sativus; vegetable; titration; pH prediction; Davies equation
MeSH headings : Algorithms; Buffers; Cucumis sativus / chemistry; Hydrogen-Ion Concentration; Ions / chemistry; Models, Chemical; Osmolar Concentration; Sensitivity and Specificity; Solutions / chemistry
topics (OpenAlex): Chemical and Physical Properties in Aqueous Solutions; Analytical Chemistry and Sensors; Electrochemical Analysis and Applications
TL;DR: A flexible, semi-mechanistic, partial buffering (SMPB) approach is presented that uses local polynomial regression to model the buffering influence of complex or undefined components in a solution, while identified components of known concentration are modeled using expressions based on extensions of the standard acid-base theory. (via Semantic Scholar)
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Added: August 6, 2018

2005 journal article

Quantifying Vasculature: New Measures Applied to Arterial Trees in the Quail Chorioallantoic Membrane

Journal of Theoretical Medicine, 6(3), 173–180.

By: S. Lubkin n , S. Funk & E. Sage

topics (OpenAlex): Fish Ecology and Management Studies; Ichthyology and Marine Biology; Retinal Imaging and Analysis
TL;DR: Two additional classes of measures based on erosions and dilations of the image are introduced, one inversely highly correlated with fractal dimension of the skeletonized image, but has a more direct biological interpretation. (via Semantic Scholar)
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15. Life on Land (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020

2003 article

Enhanced growth of tumors in SPARC null mice is associated with changes in the ECM

Brekken, R. A., Puolakkainen, P., Graves, D. C., Workman, G., Lubkin, S. R., & Sage, E. H. (2003, February 14). Journal of Clinical Investigation, Vol. 111, pp. 487–495.

By: R. Brekken *, P. Puolakkainen *, D. Graves*, G. Workman*, S. Lubkin n  & E. Sage*

topics (OpenAlex): Bone and Dental Protein Studies; Cancer, Hypoxia, and Metabolism; Cancer Research and Treatments
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 article

Enhanced growth of tumors in SPARC null mice is associated with changes in the ECM

Brekken, R. A., Puolakkainen, P., Graves, D. C., Workman, G., Lubkin, S. R., & Sage, E. H. (2003, February 15). Journal of Clinical Investigation, Vol. 111, pp. 487–495.

By: R. Brekken *, P. Puolakkainen *, D. Graves*, G. Workman*, S. Lubkin n  & E. Sage*

Contributors: R. Brekken *, P. Puolakkainen *, D. Graves*, G. Workman*, S. Lubkin n  & E. Sage*

MeSH headings : Animals; Apoptosis; Base Sequence; Cell Division; DNA / genetics; Extracellular Matrix / metabolism; Extracellular Matrix / pathology; Gene Expression; Macrophages / pathology; Macrophages / physiology; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental / genetics; Neoplasms, Experimental / metabolism; Neoplasms, Experimental / pathology; Osteonectin / deficiency; Osteonectin / genetics; Osteonectin / physiology; RNA, Messenger / genetics; RNA, Messenger / metabolism; Tumor Cells, Cultured
topics (OpenAlex): Bone and Dental Protein Studies; Cancer Research and Treatments; Connective tissue disorders research
TL;DR: It is reported that implanted tumors grew more rapidly in mice lacking SPARC and the data indicate that host-derived SPARC is important for the appropriate organization of the ECM in response to implanted tumors and highlight the importance of theECM in regulating tumor growth. (via Semantic Scholar)
Source: ORCID
Added: August 23, 2021

2002 article

Energy-Based Dynamic Model for Variable Temperature Batch Fermentation by Lactococcus lactis

Dougherty, D. P., Frederick Breidt, McFeeters, R. F., & Lubkin, S. R. (2002, May 1). Applied and Environmental Microbiology, Vol. 68, pp. 2468–2478.

By: D. Dougherty  n, . Frederick Breidt n, R. McFeeters n & S. Lubkin n 

Contributors: D. Dougherty  n, F. Breidt n, R. McFeeters n & S. Lubkin n 

MeSH headings : Calibration; Energy Metabolism; Fermentation; Lactococcus lactis / metabolism; Models, Biological; Reproducibility of Results; Temperature
topics (OpenAlex): Microbial Metabolic Engineering and Bioproduction; Listeria monocytogenes in Food Safety; thermodynamics and calorimetric analyses
TL;DR: A dynamic energy budget approach is used to model the dependence of growth on present as well as past environmental conditions and suggests plausible and testable mechanistic assumptions about the interplay between cellular energetics and the modes of inhibition by temperature and end product accumulation. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2002 article

Force and deformation on branching rudiments: cleaving between hypotheses

Lubkin, S. R., & Li, Z. (2002, June 1). Biomechanics and Modeling in Mechanobiology, Vol. 1, pp. 5–16.

By: S. Lubkin n  & Z. Li n 

Contributors: S. Lubkin n  & Z. Li n 

MeSH headings : Animals; Cell Size / physiology; Computer Simulation; Elasticity; Epithelium / anatomy & histology; Epithelium / embryology; Epithelium / growth & development; Humans; Mechanotransduction, Cellular / physiology; Mesoderm / cytology; Mesoderm / physiology; Models, Biological; Morphogenesis / physiology; Rheology / methods; Stress, Mechanical; Surface Properties; Viscosity
topics (OpenAlex): Cellular Mechanics and Interactions; Spaceflight effects on biology
TL;DR: It is proposed that a complete understanding of branching morphogenesis requires measurements of the mechanical aspects, and it is found that the surface tension, clefting force, and viscosity ratio of the two tissues have significant effects on the branching. (via Semantic Scholar)
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Added: August 6, 2018

2002 journal article

Mechanistic modeling of pH and buffer capacity during the growth of Listeria monocytogenes and Lactococcus lactis in vegetable broth medium

Abstracts of the General Meeting of the American Society for Microbiology, 102, 263. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=BCI&KeyUT=BCI:BCI200200597258&KeyUID=BCI:BCI200200597258

By: D. Dougherty, R. McFeeters, S. Lubkin  & F. Breidt

Contributors: D. Dougherty, R. McFeeters, S. Lubkin  & F. Breidt

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

2002 article

Multiphase Mechanics of Capsule Formation in Tumors

Lubkin, S. R., & Jackson, T. (2002, March 29). Journal of Biomechanical Engineering, Vol. 124, pp. 237–243.

By: S. Lubkin n  & T. Jackson *

Contributors: S. Lubkin n  & T. Jackson *

MeSH headings : Cell Count; Cell Size; Computer Simulation; Disease Progression; Elasticity; Extracellular Matrix; Fibrosis; Intercellular Junctions; Models, Biological; Neoplasms / pathology; Neoplasms / physiopathology; Osmotic Pressure; Rheology; Sensitivity and Specificity; Stress, Mechanical; Viscosity; Water / physiology
topics (OpenAlex): Cellular Mechanics and Interactions; Blood properties and coagulation; Tendon Structure and Treatment
TL;DR: It is shown that the presence of contractility in the surrounding tissue, corresponding to a host defense, can make an existing capsule denser and constrain the tumor better, but cannot be responsible for the observed pressure gradients in encapsulated tumors. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2001 journal article

An energy-based approach for modeling the batch culture of Lactococcus lactis in vegetable broth

Abstracts of the General Meeting of the American Society for Microbiology, 101, 434–435. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=BCI&KeyUT=BCI:BCI200200212002&KeyUID=BCI:BCI200200212002

By: D. Dougherty, S. Lubkin  & F. Breidt

Contributors: D. Dougherty, S. Lubkin  & F. Breidt

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

2001 journal article

Biomathematics

Encyclopedia of Mathematics Education, 77–78.

By: S. Lubkin 

Ed(s): . L. S. Grinstein & S. Lipsey

Source: NC State University Libraries
Added: August 6, 2018

2001 article

Epithelial Branching

Nakanishi, Y., Hieda, Y., Cardoso, W. V., Lubkin, S. R., & Daniel, C. W. (2001, April 19). Encyclopedia of Life Sciences.

By: Y. Nakanishi, Y. Hieda, W. Cardoso, S. Lubkin*  & C. Daniel

topics (OpenAlex): Skin and Cellular Biology Research; Developmental Biology and Gene Regulation
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2001 article

Numerical analysis of interfacial two‐dimensional Stokes flow with discontinuous viscosity and variable surface tension

Li, Z., & Lubkin, S. R. (2001, October 8). International Journal for Numerical Methods in Fluids, Vol. 37, pp. 525–540.

By: Z. Li n  & S. Lubkin n 

Contributors: Z. Li n  & S. Lubkin n 

author keywords: discontinuous and non-smooth solution; immersed interface method; interface; jump condition; Stokes equation; variable surface tension
topics (OpenAlex): Lattice Boltzmann Simulation Studies; Advanced Mathematical Modeling in Engineering; Navier-Stokes equation solutions
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

1999 article

A minimal mechanism for bacterial pattern formation

Tyson, R., Lubkin, S. R., & Murray, J. D. (1999, February 7). Proceedings of the Royal Society B Biological Sciences.

By: R. Tyson *, S. Lubkin n  & J. Murray*

author keywords: chemotaxis; bacterial patterns; mathematical modelling; bacterial aggregates; spots; stripes
MeSH headings : Bacterial Adhesion / physiology; Chemotaxis / physiology; Citric Acid Cycle; Culture Media; Escherichia coli / cytology; Escherichia coli / physiology; Models, Biological; Salmonella typhimurium / cytology; Salmonella typhimurium / physiology
topics (OpenAlex): Mathematical Biology Tumor Growth; Slime Mold and Myxomycetes Research; Gene Regulatory Network Analysis
TL;DR: A mathematical model is presented which captures all three of the pattern forming processes experimentally observed in both E. coli and S. typhimurium, using a minimum of assumptions. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

1999 journal article

A minimal mechanism for bacterial pattern formation

Proceedings of the Royal Society of London Series B-Biological Sciences, 266(1416), 299–304. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000078573000013&KeyUID=WOS:000078573000013

By: R. Tyson, S. Lubkin  & J. Murray

Contributors: R. Tyson, S. Lubkin  & J. Murray

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

1999 article

Mathematical and experimental analysis of localization of anti-tumour antibody–enzyme conjugates

Jackson, T. L., Lubkin, S. R., Siemers, N. O., Kerr, D. E., Senter, P. D., & Murray, J. D. (1999, July 9). British Journal of Cancer, Vol. 80, pp. 1747–1753.

By: T. Jackson *, S. Lubkin* , N. Siemers *, D. Kerr*, P. Senter * & J. Murray*

Contributors: T. Jackson *, S. Lubkin* , N. Siemers *, D. Kerr*, P. Senter * & J. Murray*

MeSH headings : Animals; Antibodies, Monoclonal / pharmacokinetics; Female; Humans; Immunoglobulin G / metabolism; Immunoglobulin G / therapeutic use; Kinetics; Melanoma / drug therapy; Melanoma / immunology; Melanoma / metabolism; Mice; Mice, Nude; Models, Biological; Models, Statistical; Neoplasms / drug therapy; Neoplasms / immunology; Neoplasms / metabolism; Recombinant Fusion Proteins / metabolism; Recombinant Fusion Proteins / pharmacokinetics; Recombinant Fusion Proteins / therapeutic use; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured; beta-Lactamases / metabolism; beta-Lactamases / therapeutic use
topics (OpenAlex): Monoclonal and Polyclonal Antibodies Research; HER2/EGFR in Cancer Research; Protein purification and stability
TL;DR: The model predicts that dosing strategy has little effect on the amount of conjugate that localizes in the tumour, and is used to examine various dosing strategies in an attempt to determine which regimen would provide the best biodistribution results. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

1999 article

Model and analysis of chemotactic bacterial patterns in a liquid medium

Tyson, R., Lubkin, S. R., & Murray, J. D. (1999, April 16). Journal of Mathematical Biology, Vol. 38, pp. 359–375.

By: R. Tyson *, S. Lubkin n  & J. Murray*

Contributors: R. Tyson *, S. Lubkin n  & J. Murray*

author keywords: chemotaxis; partial differential equations; bacteria; mathematical modeling; pattern formation
MeSH headings : Bacterial Physiological Phenomena; Chemotaxis / physiology; Culture Media; Escherichia coli / physiology; Linear Models; Mathematics; Models, Biological; Salmonella typhimurium / physiology
topics (OpenAlex): Mathematical Biology Tumor Growth; Gene Regulatory Network Analysis; Slime Mold and Myxomycetes Research
TL;DR: A simple and intuitively revealing analysis of the patterns generated by the modeled dynamics of the bacteria, nutrient and chemoattractant give rise to a nonlinear partial differential equation system. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

1999 article

Theoretical analysis of conjugate localization in two-step cancer chemotherapy

Jackson, T. L., Lubkin, S. R., & Murray, J. D. (1999, October 18). Journal of Mathematical Biology, Vol. 39, pp. 353–376.

By: T. Jackson *, S. Lubkin n  & J. Murray*

Contributors: T. Jackson *, S. Lubkin n  & J. Murray*

author keywords: mathematical modeling; cancer chemotherapy; antibody-enzyme conjugate
MeSH headings : Animals; Antibodies, Monoclonal / administration & dosage; Antibodies, Monoclonal / pharmacokinetics; Antibodies, Monoclonal / therapeutic use; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Antineoplastic Agents / therapeutic use; Computer Simulation; Humans; Melanoma / drug therapy; Melanoma / metabolism; Mice; Mice, Nude; Models, Biological; Numerical Analysis, Computer-Assisted; Prodrugs / administration & dosage; Prodrugs / pharmacokinetics; Prodrugs / therapeutic use; Recombinant Fusion Proteins / administration & dosage; Recombinant Fusion Proteins / pharmacokinetics; Recombinant Fusion Proteins / therapeutic use; Skin Neoplasms / drug therapy; Skin Neoplasms / metabolism; Transplantation, Heterologous; beta-Lactamases / administration & dosage; beta-Lactamases / pharmacokinetics; beta-Lactamases / therapeutic use
topics (OpenAlex): Monoclonal and Polyclonal Antibodies Research; Mathematical Biology Tumor Growth; Computational Drug Discovery Methods
TL;DR: A mathematical model based on the biology of human 3677 melanoma xenografts in nude mice is presented, analyzed, and numerically simulated to study the biodistribution, pharmacokinetics, and intratumoral localization properties of L49-β-lactamase fusion proteins in solid tumor masses. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

1998 book

A mechanical theory of in vitro vascular network formation

In Cardiovascular Molecular Morphogenesis Series; Vascular morphogenesis: In vivo, in vitro, in mente (pp. 173–188). http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=BIOSIS&KeyUT=BIOSIS:PREV199900155952&KeyUID=BIOSIS:PREV199900155952

By: J. Murray, D. Manoussaki, S. Lubkin , R. Vernon, C. Little, V. Mironov, E. Sage

Contributors: J. Murray, D. Manoussaki, S. Lubkin , R. Vernon, C. Little, V. Mironov, E. Sage

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

1998 article

Spatial pattern formation in biology: I. Dermal wound healing. II. Bacterial patterns

Murray, J. D., Cook, J., Tyson, R., & Lubkin, S. R. (1998, March 1). Journal of the Franklin Institute, Vol. 335B, pp. 303–332.

By: J. Murray*, J. Cook *, R. Tyson * & S. Lubkin* 

Contributors: J. Murray*, J. Cook *, R. Tyson * & S. Lubkin* 

topics (OpenAlex): Cellular Mechanics and Interactions; Biocrusts and Microbial Ecology; Mathematical Biology Tumor Growth
TL;DR: A model is described for the complex patterns formed by bacterial colonies, specifically Escherichia coli, and derive and analyse a model firmly based on experimental data, and the results from the model compare well with experiment. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

1997 chapter

Dynamics within tissues stresses, growth, and morphogenesis

In A. D. W. Alt & G. Dunn (Eds.), Dynamics of cell and tissue motion (pp. 211–284). Basel: Birkhauser Verlag.

By: S. Lubkin  & L. Beloussov

Ed(s): A. W. Alt & G. Dunn

Source: NC State University Libraries
Added: August 6, 2018

1997 article

Mechanisms for Branching Morphogenesis of the Lung

Lubkin, S. R. (1997, January 1). (A. D. W. Alt & G. Dunn, Eds.). Birkhäuser Basel EBooks, pp. 229–234.

By: S. Lubkin* 

Ed(s): A. Alt & G. Dunn

topics (OpenAlex): Neonatal Respiratory Health Research
TL;DR: The human lung is a dichotomously branched, hollow structure, which forms in a similar manner to other glandular organs such as the kidney, pancreas, mammary and salivary glands. (via Semantic Scholar)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

1997 book

Mechanisms for branching morphogenesis of the lung

In W. Alt, A. Deutsch, & G. Dunn (Eds.), Dynamics of Cell and Tissue Motion (pp. 229–234). http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000071666700027&KeyUID=WOS:000071666700027

By: S. Lubkin 

Contributors: S. Lubkin 

Ed(s): W. Alt, A. Deutsch & G. Dunn

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

1997 article

On Pattern Formation in Reptilian Dentition

Lubkin, S. R. (1997, May 1). Journal of Theoretical Biology, Vol. 186, pp. 145–157.

By: S. Lubkin* 

Contributors: S. Lubkin* 

topics (OpenAlex): dental development and anomalies
TL;DR: Sequences of tooth initiation are observed robustly in the model which have not hitherto been documented in vivo, suggesting the as yet undocumented occurrence of such a sequence in a living or extinct reptile. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

1997 journal article

Use of an epidemiologic model to evaluate feline leukemia virus control measures

Feline Practice, 25(4), 6–11. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997XU72500002&KeyUID=WOS:A1997XU72500002

By: J. Romatowski & S. Lubkin 

Contributors: J. Romatowski & S. Lubkin 

gateway.webofknowledge.com
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1996 article

A Mechanical Theory of In Vitro Vascular Network Formation

Murray, J. D., Manoussaki, D., Lubkin, S. R., & Vernon, R. (1996, January 1). (V. M. C. D. Little & E. H. Sage, Eds.). Birkhäuser Boston EBooks, pp. 173–188.

By: J. Murray*, D. Manoussaki*, S. Lubkin n  & R. Vernon*

Ed(s): V. Little & E. Sage

topics (OpenAlex): Cellular Mechanics and Interactions; Developmental Biology and Gene Regulation; 3D Printing in Biomedical Research
TL;DR: There has, in the past few years, been an increasing recognition among experimentalist and theoreticians that dramatic progress in biology could come about through a genuine interdisciplinary approach involving experimentalists and theoretician. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

1996 journal article

A mechanical model for the formation of vascular networks in vitro

Acta Biotheoretica, 44(3-4), 271–282. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1996VW59000008&KeyUID=WOS:A1996VW59000008

By: D. Manoussaki, S. Lubkin , R. Vernon & J. Murray

Contributors: D. Manoussaki, S. Lubkin , R. Vernon & J. Murray

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

1996 article

Evaluation of Feline Leukemia Virus Control Measures

Lubkin, S. R., Romatowski, J., Zhu, M., Kulesa, P. M., & White, K. A. J. (1996, January 1). Journal of Theoretical Biology, Vol. 178, pp. 53–60.

By: S. Lubkin* , J. Romatowski*, M. Zhu*, P. Kulesa * & K. White

Contributors: S. Lubkin* , J. Romatowski*, M. Zhu*, P. Kulesa * & K. White

MeSH headings : Animals; Cats; Disease Susceptibility; Evaluation Studies as Topic; Immunization / veterinary; Leukemia, Feline / epidemiology; Leukemia, Feline / prevention & control; Models, Biological; Population Density; Prevalence; Social Environment
topics (OpenAlex): HIV Research and Treatment; T-cell and Retrovirus Studies; Virus-based gene therapy research
TL;DR: It is concluded that the current estimated effective feline leukemia virus immunization rate of 11-19% of the general population is inadequate to provide herd immunity in the subpopulation of cats which are genuinely at risk of infection. (via Semantic Scholar)
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Source: ORCID
Added: August 23, 2021

1996 article

Modelling the spatial patterning of teeth primordia in the alligator

Kulesa, P. M., Cruywagen, G. C., Lubkin, S. R., Ferguson, M. W. J., & Murray, J. D. (1996, June 1). Acta Biotheoretica, Vol. 44, pp. 153–164.

By: P. Kulesa *, G. Cruywagen, S. Lubkin* , M. Ferguson * & J. Murray*

Contributors: P. Kulesa *, G. Cruywagen, S. Lubkin* , M. Ferguson * & J. Murray*

topics (OpenAlex): dental development and anomalies; Developmental Biology and Gene Regulation; Proteoglycans and glycosaminoglycans research
TL;DR: A dynamic patterning mechanism is developed, which crucially includes domain growth, that can reproduce the spatial pattern development of the first seven teeth primordia in each half jaw of A. mississippiensis. (via Semantic Scholar)
Source: ORCID
Added: August 23, 2021

1996 article

On a Model Mechanism for the Spatial Patterning of Teeth Primordia in the Alligator

Kulesa, P. M., Cruywagen, G. C., Lubkin, S. R., Main, P. K., Sneyd, J., Ferguson, M. W. J., & Murray, J. D. (1996, June 1). Journal of Theoretical Biology, Vol. 180, pp. 287–296.

By: P. Kulesa *, G. Cruywagen, S. Lubkin* , P. Main, J. Sneyd *, M. Ferguson *, J. Murray*

Contributors: P. Kulesa *, G. Cruywagen, S. Lubkin* , P. Maini, J. Sneyd *, M. Ferguson *, J. Murray*

topics (OpenAlex): dental development and anomalies; Developmental Biology and Gene Regulation
TL;DR: Based on biological data, a reaction-diffusion mechanism is developed which can reproduce the spatial pattern development of the first seven teeth primordia in the lower half jaw of the alligator, Alligator mississippiensis. (via Semantic Scholar)
Source: ORCID
Added: August 23, 2021

1996 journal article

Simple versus sophisticated models of breath alcohol exhalation profiles

Alcohol and Alcoholism, 31(1), 61–67. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1996UF38500008&KeyUID=WOS:A1996UF38500008

By: S. Lubkin , R. Gullberg, B. Logan, P. Maini & J. Murray

Contributors: S. Lubkin , R. Gullberg, B. Logan, P. Maini & J. Murray

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

1995 article

A mechanism for early branching in lung morphogenesis

Lubkin, S. R., & Murray, J. D. (1995, January 1). Journal of Mathematical Biology, Vol. 34, pp. 77–94.

By: S. Lubkin*  & J. Murray*

Contributors: S. Lubkin*  & J. Murray*

author keywords: LUNG; PATTERN FORMATION; MORPHOGENESIS; FETAL DEVELOPMENT
MeSH headings : Animals; Embryo, Mammalian; Embryonic and Fetal Development; Humans; Lung / anatomy & histology; Lung / embryology; Mathematics; Models, Biological; Morphogenesis
topics (OpenAlex): Scientific Research and Discoveries; Earth Systems and Cosmic Evolution; Magnetic and Electromagnetic Effects
TL;DR: It is suggested that the repeated branching of the early embryonic lung can be understood as the natural physical consequence of the interactions of two or more plastic substances with surface tension between them. (via Semantic Scholar)
Source: ORCID
Added: August 23, 2021

1995 book

A pair formation approach to modeling inheritance of social traits

In V. Lakshmikantham (Ed.), World Congress of Nonlinear Analysis '92, Vols 1-4 (pp. 3227–3234). http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1995BF46J00295&KeyUID=WOS:A1995BF46J00295

By: S. Lubkin  & C. CastilloChavez

Contributors: S. Lubkin  & C. CastilloChavez

Ed(s): V. Lakshmikantham

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

1995 journal article

Modelling the spatial patterning of the teeth primordia in the lower jaw of Alligator mississippiensis

Journal of Biological Systems, Vol 3, Nos 1-4, 1995: Special Issue: 2nd Ecmbm-Lyon, Pts 1-4, 975–985. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1995BF06V00086&KeyUID=WOS:A1995BF06V00086

By: P. Kulesa, G. Cruywagen, S. Lubkin , P. Maini, J. Sneyd & J. Murray

Contributors: P. Kulesa, G. Cruywagen, S. Lubkin , P. Maini, J. Sneyd & J. Murray

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

1994 article

Oscillatory reaction-diffusion equations on rings

Lubkin, S., & Rand, R. (1994, January 1). Journal of Mathematical Biology, Vol. 32, pp. 617–632.

By: S. Lubkin*  & R. Rand *

Contributors: S. Lubkin*  & R. Rand *

author keywords: OSCILLATORS; BIFURCATIONS; REACTION-DIFFUSION EQUATIONS; SPATIAL HETEROGENEITY
topics (OpenAlex): Nonlinear Dynamics and Pattern Formation; Mathematical and Theoretical Epidemiology and Ecology Models; stochastic dynamics and bifurcation
Source: ORCID
Added: August 23, 2021

1994 article

Unidirectional waves on rings: Models for chiral preference of circumnutating plants

LUBKIN, S. (1994, September 1). Bulletin of Mathematical Biology, Vol. 56, pp. 795–810.

By: S. Lubkin* 

Contributors: S. Lubkin* 

topics (OpenAlex): Plant Reproductive Biology; Plant Molecular Biology Research; Plant Physiology and Cultivation Studies
TL;DR: Wave phenomena on asymmetric but isotropic rings, and seek systems which will only support (stable) waves in one direction around the ring, and not in the other, indicate that chiral asymmetries of circumnutating plants cannot be explained by continuum oscillator phenomena, but can be explaining by general discrete oscillators, or excitable phenomena on the continuum. (via Semantic Scholar)
Source: ORCID
Added: August 23, 2021

1992 journal article

A thin-shell model of the cornea and its application to corneal surgery.

Refractive &Amp; Corneal Surgery, 8(2), 183–186. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:1591214&KeyUID=MEDLINE:1591214

By: H. Howland, R. Rand & S. Lubkin 

Contributors: H. Howland, R. Rand & S. Lubkin 

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

1991 article

Analytical Model of Corneal Surgery

Rand, R. H., Lubkin, S. R., & Howland, H. C. (1991, May 1). Journal of Biomechanical Engineering, Vol. 113, pp. 239–241.

By: R. Rand *, S. Lubkin*  & H. Howland*

Contributors: R. Rand *, S. Lubkin*  & H. Howland*

MeSH headings : Cornea / pathology; Cornea / physiopathology; Elasticity; Humans; Intraocular Pressure / physiology; Keratotomy, Radial; Models, Biological
topics (OpenAlex): Corneal surgery and disorders; Corneal Surgery and Treatments
TL;DR: A model of the human cornea is presented in order to study the changes in its shape resulting from surgical operations, and the effect of surgery on corneal flattening and the associated sensitivity to intraocular pressure changes is investigated. (via Semantic Scholar)
Source: ORCID
Added: August 23, 2021

1990 journal article

ANALYTICAL MODEL OF CORNEAL SURGERY

Investigative Ophthalmology and Visual Science, 31(4 ABSTR. ISSUE), 481. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=BCI&KeyUT=BCI:BCI199039098517&KeyUID=BCI:BCI199039098517

By: H. C, R. H & L. R

Contributors: H. Howland, R. Rand & S. Lubkin 

gateway.webofknowledge.com
Source: ORCID
Added: August 23, 2021

Employment

Updated: January 22nd, 2026 18:22

1997 - present

North Carolina State University Raleigh, NC, US

Education

Updated: January 22nd, 2015 09:48

1987 - 1992

Cornell University Ithaca, NY, US
PhD

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