Works (41)

Updated: May 25th, 2023 05:00

2023 article

Effect of gentamicin on CD3+T-lymphocyte proliferation for treatment of equine recurrent uveitis: An in vitro study

Smith, H. L., Berglund, A. K., Robertson, J. B., Schnabel, L. V., McMullen, R. J., Gilger, B. C., & Oh, A. (2023, April 28). VETERINARY OPHTHALMOLOGY, Vol. 4.

author keywords: autoimmune disease; equine recurrent uveitis; gentamicin; horse; immunology; intravitreal injection
Sources: Web Of Science, ORCID
Added: April 29, 2023

2023 journal article

Pneumatic compression therapy using the EQ Press accelerates lymphatic flow in healthy equine forelimbs as determined by lymphoscintigraphy

AMERICAN JOURNAL OF VETERINARY RESEARCH, 84(4).

By: D. Koch, L. Schnabel, J. Reynolds & C. Berry n

Source: Web Of Science
Added: May 22, 2023

2022 journal article

A Platelet-Rich Plasma-Derived Biologic Clears Staphylococcus aureus Biofilms While Mitigating Cartilage Degeneration and Joint Inflammation in a Clinically Relevant Large Animal Infectious Arthritis Model

Frontiers in Cellular and Infection Microbiology, 12.

By: J. Gilbertie, T. Schaer, J. Engiles, G. Seiler, B. Deddens, A. Schubert, M. Jacob, D. Stefanovski ...

author keywords: infectious arthritis; S; aureus; biofilm; antimicrobial; platelets; cartilage; synovium; synovial fluid
Sources: Web Of Science, Crossref, ORCID
Added: June 20, 2022

2022 article

Alterations to the synovial invaginations of the navicular bone are associated with pathology of both the navicular apparatus and distal interphalangeal joint when evaluated using high field MRI

McParland, T. J., Horne, C. R., Robertson, J. B., Schnabel, L. V., & Nelson, N. C. (2022, August 15). VETERINARY RADIOLOGY & ULTRASOUND, Vol. 8.

By: T. McParland, C. Horne, J. Robertson, L. Schnabel & N. Nelson

author keywords: distal sesamoid bone; foot; horse; imaging
Sources: Web Of Science, ORCID
Added: August 22, 2022

2022 journal article

Interleukin-1 beta in tendon injury enhances reparative gene and protein expression in mesenchymal stem cells

FRONTIERS IN VETERINARY SCIENCE, 9.

author keywords: tendon; cytokine; ultrafiltration probe; mesenchymal stem cell; licensing
Source: Web Of Science
Added: December 12, 2022

2022 article

Leveraging MRI characterization of longitudinal tears of the deep digital flexor tendon in horses using machine learning

ELKhamary, A. N., Keenihan, E. K., Schnabel, L. V., Redding, W. R., & Schumacher, J. (2022, April 12). VETERINARY RADIOLOGY & ULTRASOUND.

By: A. ELKhamary*, E. Keenihan, L. Schnabel, W. Redding & J. Schumacher*

author keywords: equine; feature extraction; longitudinal tear grading; machine learning classifier; tenoscopy
Source: Web Of Science
Added: April 25, 2022

2022 article

Non-steroidal anti-inflammatory drugs in equine orthopaedics

Jacobs, C. C., Schnabel, L. V., McIlwraith, C. W., & Blikslager, A. T. (2022, February 10). EQUINE VETERINARY JOURNAL, Vol. 2.

By: C. Jacobs, L. Schnabel, C. McIlwraith* & A. Blikslager

author keywords: horse; non-steroidal anti-inflammatory drug; orthopaedics; osteoarthritis
Sources: Web Of Science, ORCID
Added: February 28, 2022

2022 journal article

Potent Activity of Ertapenem Plus Cefazolin Within Staphylococcal Biofilms: A Contributing Factor in the Treatment of Methicillin-Susceptible Staphylococcus aureus Endocarditis

OPEN FORUM INFECTIOUS DISEASES, 9(5).

By: J. Gilbertie, E. Ulloa*, J. Daiker, K. Nguyen*, D. Smelter*, W. Rose*, M. Geriak*, L. Schnabel, V. Nizet*, G. Sakoulas*

author keywords: cefazolin; ertapenem; endocarditis; Staphylococcus aureus
Source: Web Of Science
Added: May 10, 2022

2022 journal article

TGF-beta 2 enhances expression of equine bone marrow-derived mesenchymal stem cell paracrine factors with known associations to tendon healing

STEM CELL RESEARCH & THERAPY, 13(1).

By: D. Koch, L. Schnabel, I. Ellis, R. Bates & A. Berglund

author keywords: Mesenchymal stem cell; Tenocyte; TGF-beta 2; Equine; Tendon; RNA-sequencing; Paracrine factors; Extracellular matrix
Source: Web Of Science
Added: September 26, 2022

2022 article

TLR-activated mesenchymal stromal cell therapy and antibiotics to treat multi-drug resistant Staphylococcal septic arthritis in an equine model

Pezzanite, L. M., Chow, L., Phillips, J., Griffenhagen, G. M., Moore, A. R., Schaer, T. P., … Goodrich, L. R. (2022, September 23). ANNALS OF TRANSLATIONAL MEDICINE.

By: L. Pezzanite, L. Chow, J. Phillips, G. Griffenhagen, A. Moore, T. Schaer, J. Engiles, N. Werpy ...

author keywords: Antibiotic resistance; infectious arthritis; mesenchymal stromal cell (MSC)
Source: Web Of Science
Added: November 28, 2022

2022 article

Tendon sheath masses - What are the differential diagnoses and what diagnostics are needed?

Schnabel, L. V., Horne, C. R., & Jacobs, C. C. (2022, June 13). EQUINE VETERINARY EDUCATION.

By: L. Schnabel, C. Horne & C. Jacobs

Source: Web Of Science
Added: June 27, 2022

2021 journal article

Adeno-Associated Virus-Mediated Overexpression of Interleukin-10 Affects the Immunomodulatory Properties of Equine Bone Marrow-Derived Mesenchymal Stem Cells

HUMAN GENE THERAPY, 32(17-18), 907–918.

By: A. Cameron*, K. Even*, R. Linardi*, A. Berglund, L. Schnabel, J. Engiles*, K. Ortved*

author keywords: osteoarthritis; PTOA; immunomodulation; mesenchymal stem cell; IL-10; AAV
Source: Web Of Science
Added: May 24, 2021

2021 journal article

Cross-matching of allogeneic mesenchymal stromal cells eliminates recipient immune targeting

STEM CELLS TRANSLATIONAL MEDICINE, 10(5), 694–710.

By: A. Rowland*, D. Miller*, A. Berglund, L. Schnabel, G. Levine*, D. Antczak*, A. Watts*

author keywords: allogeneic; alloimmunization; antibody; autologous; cross‐ match; humoral; innate; intra‐ articular; major histocompatibility complex (MHC); MSC
Source: Web Of Science
Added: January 11, 2021

2021 article

Effects of continuous passage on the immunomodulator properties of equine bone marrow-derived mesenchymal stem cells in vitro (vol 234, 110203, 2021)

Connard, S. S., Linardi, R. L., Even, K. M., Berglund, A. K., Schnabel, L. V., & Ortved, K. F. (2021, December). VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, Vol. 242.

By: S. Connard*, R. Linardi*, K. Even*, A. Berglund, L. Schnabel & K. Ortved*

Source: Web Of Science
Added: March 7, 2022

2021 journal article

Effects of continuous passage on the immunomodulatory properties of equine bone marrow-derived mesenchymal stem cells in vitro

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 234.

By: S. Connard*, R. Linardi*, K. Even*, A. Berglund, L. Schnabel & K. Ortved*

author keywords: Horse; Mesenchymal stem cells; Continuous passage; Immunomodulation
Source: Web Of Science
Added: October 12, 2021

2021 journal article

Pathology in Practice

Journal of the American Veterinary Medical Association, 258(9), 961–964.

Sources: Web Of Science, Crossref, ORCID
Added: June 10, 2021

2021 journal article

TGF-beta 2 Reduces the Cell-Mediated Immunogenicity of Equine MHC-Mismatched Bone Marrow-Derived Mesenchymal Stem Cells Without Altering Immunomodulatory Properties

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 9.

By: A. Berglund, J. Long, J. Robertson & L. Schnabel

author keywords: mesenchymal stem cell; TGF-β 2; cytotoxicity; immunogenicity; major histocompatibility complex; allogeneic
Sources: Web Of Science, ORCID
Added: March 8, 2021

2021 journal article

The combination of mitogenic stimulation and DNA damage induces chondrocyte senescence

OSTEOARTHRITIS AND CARTILAGE, 29(3), 402–412.

By: M. Copp, M. Flanders n, R. Gagliardi, J. Gilbertie, G. Sessions*, S. Chubinskaya*, R. Loeser*, L. Schnabel, B. Diekman

author keywords: SA-beta-gal; DNA damage; Osteoarthritis; Aging; TGF- beta 1; bFGF
Source: Web Of Science
Added: March 29, 2021

2020 journal article

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

NATURE COMMUNICATIONS, 11(1).

By: P. Dinh, D. Paudel n, H. Brochu, K. Popowski, M. Gracieux n, J. Cores, K. Huang, M. Hensley n ...

Sources: Web Of Science, ORCID
Added: March 23, 2020

2020 journal article

One health in regenerative medicine: report on the second Havemeyer symposium on regenerative medicine in horses

REGENERATIVE MEDICINE, 15(6), 1775–1787.

By: L. Fortier*, L. Goodrich*, I. Ribitsch*, L. Schnabel, D. Shepard*, A. Watts*, R. Smith*

author keywords: animal model; bone marrow concentrate; horse; interleukin-1 receptor antagonist protein; mesenchymal stem cell; platelet rich plasma; stem cell
Source: Web Of Science
Added: August 31, 2020

2020 journal article

Platelet-rich plasma lysate displays antibiofilm properties and restores antimicrobial activity against synovial fluid biofilms in vitro

JOURNAL OF ORTHOPAEDIC RESEARCH, 38(6), 1365–1374.

By: J. Gilbertie, T. Schaer*, A. Schubert, M. Jacob, S. Menegatti, R. Lavoie n, L. Schnabel

author keywords: biofilms; equine model; infectious arthritis; platelet-rich plasma; Staphylococcus aureus
Sources: Web Of Science, ORCID
Added: January 27, 2020

2019 article

5-Benzylidene-4-Oxazolidinones Are Synergistic with Antibiotics for the Treatment of Staphylococcus aureus Biofilms

CHEMBIOCHEM, Vol. 12.

By: B. Frohock, J. Gilbertie, J. Daiker, L. Schnabel & J. Pierce

Sources: Web Of Science, ORCID
Added: January 13, 2020

2019 journal article

Effects of acellular equine amniotic allografts on the healing of experimentally induced full-thickness distal limb wounds in horses

VETERINARY SURGERY, 48(8), 1416–1428.

Source: Web Of Science
Added: August 26, 2019

2019 journal article

Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections

PLOS ONE, 14(8).

Source: Web Of Science
Added: September 30, 2019

2019 journal article

Oral reserpine administration in horses results in low plasma concentrations that alter platelet biology

EQUINE VETERINARY JOURNAL, 51(4), 537–543.

By: J. Gilbertie n, J. Davis, G. Davidson, A. McDonald n, J. Schirmer & L. Schnabel

author keywords: horse; reserpine; pharmacokinetics; tranquilisation; platelets; hypercoagulability
Source: Web Of Science
Added: July 22, 2019

2018 review

Diagnosis and management of proximal sesamoid bone fractures in the horse

[Review of ]. EQUINE VETERINARY EDUCATION, 30(8), 450–455.

By: L. Schnabel & W. Redding

author keywords: horse; proximal sesamoid bone; fracture; arthroscopy
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Gram-negative multi-drug resistant bacteria influence survival to discharge for horses with septic synovial structures: 206 Cases (2010-2015)

VETERINARY MICROBIOLOGY, 226, 64–73.

author keywords: Septic synovitis; Infectious arthritis; Equine; Multi-drug resistance (MDR); Fluoroquinolones; Gram-negative bacteria
Source: Web Of Science
Added: December 3, 2018

2018 journal article

Inflammatory licensed equine MSCs are chondroprotective and exhibit enhanced immunomodulation in an inflammatory environment

STEM CELL RESEARCH & THERAPY, 9.

By: J. Cassano*, L. Schnabel, M. Goodale* & L. Fortier*

author keywords: Mesenchymal stem cells; Immunomodulation; Inflammatory licensing; Licensing; Polarization; Regenerative medicine
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Pooled Platelet-Rich Plasma Lysate Therapy Increases Synoviocyte Proliferation and Hyaluronic Acid Production While Protecting Chondrocytes From Synoviocyte-Derived Inflammatory Mediators

FRONTIERS IN VETERINARY SCIENCE, 5.

By: J. Gilbertie n, J. Long, A. Schubert n, A. Berglund, T. Schaer* & L. Schnabel

author keywords: platelet-rich plasma lysate; osteoarthritis; IL-1 beta; LPS; HA; collagen type II; aggrecan; MMP-13
Source: Web Of Science
Added: December 17, 2018

2018 journal article

The immunomodulatory function of equine MSCs is enhanced by priming through an inflammatory microenvironment or TLR3 ligand

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 195, 33–39.

By: J. Cassano*, L. Schnabel, M. Goodale* & L. Fortier*

author keywords: Mesenchymal stem cells; MSC; Immunomodulation; TLR; Polarization; Regenerative medicine
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Allogeneic major histocompatibility complex-mismatched equine bone marrow-derived mesenchymal stem cells are targeted for death by cytotoxic anti-major histocompatibility complex antibodies

EQUINE VETERINARY JOURNAL, 49(4), 539–544.

By: A. Berglund & L. Schnabel

author keywords: horse; mesenchymal stem cell; allogeneic; major histocompatibility complex-mismatched; antibody response; complement-dependent cytotoxicity
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Effect of bone marrow-derived mesenchymal stem cells and stem cell supernatant on equine corneal wound healing in vitro

Stem Cell Research & Therapy, 8(1).

By: A. Sherman, B. Gilger, A. Berglund & L. Schnabel

author keywords: Mesenchymal stem cells; Equine; Corneal wound healing; Corneal stromal cells/fibroblasts; Scratch assay; TGF-beta 1
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2016 journal article

Navigational ultrasound imaging: A novel imaging tool for aiding interventional therapies of equine musculoskeletal injuries

EQUINE VETERINARY JOURNAL, 48(2), 195–200.

author keywords: horse; navigational ultrasound imaging; fusion imaging; musculoskeletal; MRI
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Equine allogeneic bone marrow-derived mesenchymal stromal cells elicit antibody responses in vivo

STEM CELL RESEARCH & THERAPY, 6.

By: L. Pezzanite*, L. Fortier*, D. Antczak*, J. Cassano*, M. Brosnahan*, D. Miller*, L. Schnabel

Source: Web Of Science
Added: August 6, 2018

2015 journal article

Mesenchymal Stem Cell Therapy: Clinical Progress and Opportunities for Advancement

Current Pathobiology Reports, 3(1), 1–7.

By: J. Cassano*, L. Schnabel, A. Betancourt*, D. Antczak* & L. Fortier*

Source: Crossref
Added: February 24, 2020

2014 journal article

Equine bone marrow-derived mesenchymal stromal cells are heterogeneous in MHC class II expression and capable of inciting an immune response in vitro

STEM CELL RESEARCH & THERAPY, 5.

By: L. Schnabel, L. Pezzanite*, D. Antczak*, M. Felippe* & L. Fortier*

Source: Web Of Science
Added: August 6, 2018

2014 journal article

Induced pluripotent stem cells have similar immunogenic and more potent immunomodulatory properties compared with bone marrow-derived stromal cells in vitro

REGENERATIVE MEDICINE, 9(5), 621–635.

By: L. Schnabel, C. Abratte*, J. Schimenti*, M. Felippe*, J. Cassano*, T. Southard*, J. Cross*, L. Fortier*

author keywords: allogeneic stem cell therapy; immunogenicity; immunomodulatory; induced pluripotent stem cell; mesenchymal stromal cell; transplantation medicine
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Therapeutic use of stem cells in horses: Which type, how, and when?

The Veterinary Journal, 197(3), 570–577.

By: L. Schnabel, L. Fortier*, C. Wayne McIlwraith* & K. Nobert*

author keywords: Stem cells; Equine musculoskeletal disorders; Tendonitis; Osteoarthritis; FDA
Source: Crossref
Added: February 24, 2020

2012 journal article

Cell- and gene-based approaches to tendon regeneration

Journal of Shoulder and Elbow Surgery, 21(2), 278–294.

By: A. Nixon, A. Watts & L. Schnabel

author keywords: Tendon; rotator cuff; shoulder; MSC; stem cells; gene therapy; regeneration
Source: Crossref
Added: February 24, 2020

2009 journal article

Mesenchymal stem cells and insulin-like growth factor-I gene-enhanced mesenchymal stem cells improve structural aspects of healing in equine flexor digitorum superficialis tendons

Journal of Orthopaedic Research, 27(10), 1392–1398.

By: L. Schnabel, M. Lynch*, M. van der Meulen*, A. Yeager*, M. Kornatowski* & A. Nixon*

author keywords: mesenchymal stem cells; IGF-I; gene therapy; tendinitis; in vivo
Source: Crossref
Added: December 29, 2020

2007 journal article

Platelet rich plasma (PRP) enhances anabolic gene expression patterns in flexor digitorum superficialis tendons

Journal of Orthopaedic Research, 25(2), 230–240.

By: L. Schnabel, H. Mohammed*, B. Miller*, W. McDermott*, M. Jacobson*, K. Santangelo*, L. Fortier*

author keywords: platelet rich plasma (PRP); tendonitis; collagen; cartilage oligomeric matrix protein (COMP); matrix metalloproteinase (MMP)
Source: Crossref
Added: February 24, 2020