Lauren V Schnabel

Cell and Gene Therapy in Equine Ocular Disease

Young, K. A. S., Schnabel, L. V., & Gilger, B. C. (2026, February 2). Veterinary Ophthalmology, Vol. 2.

Extracorporeal shock wave therapy in equine and canine practice

Horne, C. R., & Schnabel, L. V. (2026, March 6). Journal of the American Veterinary Medical Association.

The Effect of Lipemia on Insulin and Adiponectin Measurement in Equine Blood Samples

Hallowell, K. L., Eps, A. W., Kulp, J. C., & Schnabel, L. V. (2026, February 16). Veterinary Clinical Pathology.

Alpha2EQ downregulates proinflammatory cytokine and chemokine gene expression in cultured synovial fibroblasts

Pugliese, B. R., Rosario, F. K. R., & Schnabel, L. V. (2025, December 30). American Journal of Veterinary Research, Vol. 12.

Comparison of a dorsolateral approach and a dorsomedial approach to access the medial malleolus of the distal tibia in horses

Veterinary Surgery, 3.

Current and Emerging Biologic Therapies for Equine Tendon and Ligament Injuries

Connard, S. S., & Schnabel, L. V. (2025, June 13). Veterinary Clinics of North America Equine Practice, Vol. 41, pp. 371–389.

Equine neutrophils selectively release neutrophil extracellular traps in response to chemical and bacterial agonists

Sheahan, B. J., Schubert, A. G., Schubert, W., Sheats, M. K., Schnabel, L. V., & Gilbertie, J. M. (2025, February 24). Frontiers in Veterinary Science, Vol. 12.

Evidence for alpha-2-macroglobulin as an orthobiologic osteoarthritis therapy: a narrative review

Pugliese, B. R., & Schnabel, L. V. (2025, October 31). American Journal of Veterinary Research.

Noninvasive Fibrin Targeting Colloid‐Mediated Intra‐Articular Repair

Journal of Biomedical Materials Research Part A, 113(4).

Postoperative management following equine orthopedic surgery: a survey of diplomates of the ACVS and ACVSMR

Jacobs, C., Schnabel, L. V., Horne, C. R., Tufts, S., Martin, E. G. M., & Love, K. (2025, December 5). Frontiers in Veterinary Science, Vol. 12.

A NOVEL MATRIKINE STIMULATED EQUINE SYNOVIAL FIBROBLAST AND CHONDROCYTE CO-CULTURE MODEL OF OSTEOARTHRITIS: A PROPOSED ALTERNATIVE TO TRADITIONAL LPS AND IL-1B MODELS

Gagliardi, R., Loeser, R. F., & Schnabel, L. (2024, May 23). Osteoarthritis and Cartilage, Vol. 32, pp. 780–781.

A novel matrikine stimulated equine synovial fibroblast and chondrocyte co-culture model of osteoarthritis: a proposed alternative to traditional LPS and Il-1b models

OARSI 2024 World Congress on Osteoarthritis. Presented at the OARSI 2024 World Congress on Osteoarthritis.

Animal drug shortages limit veterinary therapeutic options and introduce artifacts in antimicrobial sales reporting

Journal of the American Veterinary Medical Association, 262(4), 576–579.

Controlled Stiffness of Direct-Write, Near-Field Electrospun Gelatin Fibers Generates Differences in Tenocyte Morphology and Gene Expression

Journal of Biomechanical Engineering, 146(9).

Early degenerative changes are different between partial and complete anterior cruciate ligament injury and associate with joint instability in a skeletally immature porcine model

Osteoarthritis and Cartilage, 33(2), 302–312.

Editorial: Links between regenerative medicine and immunotherapy: how cellular therapies modulate immune responses for improved outcomes

Pezzanite, L., Barrachina, L., & Schnabel, L. (2024, July 26). Frontiers in Veterinary Science, Vol. 11.

Equity and Equine Medicine

North Carolina Veterinary Conference. Presented at the North Carolina Veterinary Conference, Raleigh, NC.

Expanded library of novel 2,3-pyrrolidinedione analogues exhibit anti-biofilm activity

Bioorganic & Medicinal Chemistry Letters, 99, 129609.

Fighting fibrin with fibrin: Vancomycin delivery into coagulase‐mediated Staphylococcus aureus biofilms via fibrin‐based nanoparticle binding

Journal of Biomedical Materials Research Part A, 112(12), 2071–2085.

IL-1β + TGF-β2 dual-licensed mesenchymal stem cells have reduced major histocompatibility class I expression and positively modulate tenocyte migration, metabolism, and gene expression

Journal of the American Veterinary Medical Association, 262(S1), S61–S72.

Initial Investigation into the Effects of Tissue Plasminogen Activator on Intrasynovial Tenocytes In Vitro

Presented at the 2024 American College of Veterinary Sports Medicine and Rehabilitation Symposium Scientific/Clinical Abstract Sessions.

Matrikine stimulation of equine synovial fibroblasts and chondrocytes results in an in vitro osteoarthritis phenotype

Journal of Orthopaedic Research, 43(2), 292–303.

Mitigating the Risk of Corticosteroid-Induced Laminitis

Association of Equine Practitioners (AAEP) Convention and Trade Show. Presented at the Association of Equine Practitioners (AAEP) Convention and Trade Show, Orlando, FL.

No correlation found between palpation and ultrasound for evaluation of effusion in the medial femorotibial and femoropatellar joint compartments of horses

Journal of the American Veterinary Medical Association, 262(4), 476–480.

Palpation and Ultrasound Assessment of Naturally Occurring Effusion of the Equine Stifle

Presented at the 2024 American College of Veterinary Sports Medicine and Rehabilitation Symposium Scientific/Clinical Abstract Sessions.

Pyrrolidine-2,3-diones: heterocyclic scaffolds that inhibit and eradicate S. aureus biofilms

Chemical Communications, 60(81), 11540–11543.

Surgical procedure of intratympanic injection and inner ear pharmacokinetics simulation in domestic pigs

Frontiers in Pharmacology, 15.

Systemic Absorption of Triamcinolone Acetonide Following Intrasynovial and Extrasynovial Articular Injection

AAEP Convention. Presented at the AAEP Convention.

Systemic absorption of triamcinolone acetonide is increased from intrasynovial versus extrasynovial sites and induces hyperglycemia, hyperinsulinemia, and suppression of the hypothalamic-pituitary-adrenal axis

Frontiers in Veterinary Science, 11.

Temperature has a greater effect than salinity on microbial survival in saltwater from a single equine hydrotherapy unit

American Journal of Veterinary Research, 85(11).

Ultrasoft platelet-like particles stop bleeding in rodent and porcine models of trauma

Science Translational Medicine, 16(742).

Understanding the Potent Antibiofilm Activity of Natural Product-derived Lipoxazolidinones

North Carolina Branch ASM Annual Meeting and Research Symposium. Presented at the North Carolina Branch ASM Annual Meeting and Research Symposium, Wilmington, NC.

A Novel Equine In Vitro Model of Osteoarthritis Utilizing Fibronectin Fragment (FN7-10) Stimulated Synovial Fibroblasts and Chondrocytes

ACVS Surgery Summit 2023. Poster presented at the ACVS Surgery Summit 2023.

Advances in the diagnosis of tendon and ligament injuries

Florida Association of Equine Practitioners (FAEP) Promoting Excellence Symposium. Presented at the Florida Association of Equine Practitioners (FAEP) Promoting Excellence Symposium, West Palm Beach, FL.

Antimicrobial Properties of Equine Stromal Cells and Platelets and Future Directions

Veterinary Clinics of North America: Equine Practice, 39(3), 565–578.

Back Pain in the Horse: Diagnosis and Management

North Carolina Veterinary Conference. Presented at the North Carolina Veterinary Conference, Raleigh, NC.

Biofilm formation in septic synovitis and novel therapies

American College of Veterinary Surgeons Surgery Summit. Presented at the American College of Veterinary Surgeons Surgery Summit, Louisville, KY.

Common causes of fetlock pain, management, and prognosis

The Equine Practice Company Lameness Program. Presented at the The Equine Practice Company Lameness Program.

Considerations for the Use of Biologic and Regenerative Therapies in Equine Practice

Veterinary Clinics of North America: Equine Practice, 39(3), xiii-xiv.

Degenerative Changes Are Associated with Joint Stability after Partial and Complete ACL Injury in a Skeletally Immature Porcine Model

`ORS (Orthopaedic Research Society) Annual Meeting 2023. Presented at the ORS (Orthopaedic Research Society) Annual Meeting 2023.

Effect of gentamicin on CD3+ T‐lymphocyte proliferation for treatment of equine recurrent uveitis: An in vitro study

Veterinary Ophthalmology, 26(4), 347–354.

Enhanced Clotting in Synovial Fluid with Colloidal-Composite Gels for Partial Anterior Cruciate Ligament Tears

ORS (Orthopaedic Research Society) Annual Meeting 2023. Poster presented at the ORS (Orthopaedic Research Society) Annual Meeting 2023.

Evaluating the safety and efficacy of allogeneic stem cell products: what do you need to know?

Locomotion in Practice 2023. Presented at the Locomotion in Practice 2023, Netherlands.

IL-1b and TGF-b2 dual licensed mesenchymal stem cells downregulate MHC I expression and enhance tendon fibroblast migration in vitro

ACVS Surgery Summit 2023. Poster presented at the ACVS Surgery Summit 2023.

Mesenchymal stem cell licensing: enhancing MSC function as a translational approach for the treatment of tendon injury

American Journal of Veterinary Research, 84(10), 1–8.

Neo-natal castration leads to subtle differences in porcine anterior cruciate ligament morphology and function in adolescence

Thompson, J. D., Howe, D., Griffith, E. H., Schnabel, L. V., & Fisher, M. B. (2023, January 25).

New Horizons in Viscosupplementation and Rehabilitation for the Treatment of Joint Disease

American Association of Equine Veterinary Technicians and Assistants Convention. Presented at the American Association of Equine Veterinary Technicians and Assistants Convention, San Diego, CA.

Orthobiologics for soft tissue injuries

American College of Veterinary Sports Medicine and Rehabilitation Symposium. Presented at the American College of Veterinary Sports Medicine and Rehabilitation Symposium, Charleston, SC.

Pneumatic Compression Therapy Using the EQ Press Accelerates Lymphatic Flow in Healthy Equine Forelimbs as Determined by Lymphoscintigraphy

Presented at the 2023 American College of Veterinary Sports Medicine and Rehabilitation Symposium Scientific/Clinical Abstract Sessions.

Pneumatic compression therapy using the EQ Press accelerates lymphatic flow in healthy equine forelimbs as determined by lymphoscintigraphy

American Journal of Veterinary Research, 84(4), 1–6.

Point-of-care biologics and viscoelastic therapies for the treatment of musculoskeletal injuries

Florida Association of Equine Practitioners (FAEP) Promoting Excellence Symposium. Presented at the Florida Association of Equine Practitioners (FAEP) Promoting Excellence Symposium, West Palm Beach, FL.

Preclinical tendon and ligament models: Beyond the 3Rs (replacement, reduction, and refinement) to 5W1H (why, who, what, where, when, how)

Journal of Orthopaedic Research, 41(10), 2133–2162.

Rehabilitation and monitoring of tendon and ligament injuries

Florida Association of Equine Practitioners Promoting Excellence Symposium (FAEP). Presented at the Florida Association of Equine Practitioners Promoting Excellence Symposium (FAEP), West Palm Beach, FL.

Systemic Absorption of Triamcinolone Acetonide following Intrasynovial and Extrasynovial Articular Injection

Presented at the 2023 American College of Veterinary Sports Medicine and Rehabilitation Symposium Scientific/Clinical Abstract Sessions.

TGF-β downregulates antigen processing and presentation genes and MHC I surface expression through a Smad3-dependent mechanism

Berglund, A. K., Hinson, A. L., & Schnabel, L. V. (2023, February 1).

Use of mesenchymal stem cells for tendon healing in veterinary and human medicine: getting to the “core” of the problem through a one health approach

Journal of the American Veterinary Medical Association, 261(10), 1435–1442.

Use of stem cells for the treatment of musculoskeletal injuries: what type, how, and when?

Florida Association of Equine Practitioners (FAEP) Promoting Excellence Symposium. Presented at the Florida Association of Equine Practitioners (FAEP) Promoting Excellence Symposium, West Palm Beach, FL.

Variable stiffness Crosslinking method of aligned direct-write, near-field electrospun gelatin fibers alter stiffness, cytocompatibility, and increased cellular aspect ratios of tenocytes

ORS (Orthopaedic Research Society) Annual Meeting 2023. Poster presented at the ORS (Orthopaedic Research Society) Annual Meeting 2023.

Viscoelastic therapies for osteoarthritis management

American College of Veterinary Sports Medicine and Rehabilitation Symposium. Presented at the American College of Veterinary Sports Medicine and Rehabilitation Symposium, Charleston, SC.

A Model of Orthopedic Device-Related Infection Due to Staphylococcus aureus Biofilms

NCSU Litwack Research Day. Poster presented at the NCSU Litwack Research Day.

A Platelet-Rich Plasma-Derived Biologic Clears Staphylococcus aureus Biofilms While Mitigating Cartilage Degeneration and Joint Inflammation in a Clinically Relevant Large Animal Infectious Arthritis Model

Frontiers in Cellular and Infection Microbiology, 12.

A call to action for veterinarians and partners in animal health to collect antimicrobial use data for the purposes of supporting medical decision-making and antimicrobial stewardship

Journal of the American Veterinary Medical Association, 260(8), 853–859.

ACL Injury Impacts Long-Term Knee Function and Tissue Remodeling in a Skeletally Immature Porcine Model

ORS (Orthopaedic Research Society) Annual Meeting. Presented at the ORS (Orthopaedic Research Society) Annual Meeting.

Advances in the diagnosis and treatment of septic synovial structures

Maryland Delaware Veterinary Medical Association Annual Summer Conference. Presented at the Maryland Delaware Veterinary Medical Association Annual Summer Conference, Ocean City, MD.

Advances in the diagnosis of tendon and ligament injuries

Maryland Delaware Veterinary Medical Association Annual Summer Conference. Presented at the Maryland Delaware Veterinary Medical Association Annual Summer Conference, Ocean City, MD.

Alterations to the synovial invaginations of the navicular bone are associated with pathology of both the navicular apparatus and distal interphalangeal joint when evaluated using high field MRI

Veterinary Radiology & Ultrasound, 64(1), 9–17.

Alterations to the synovial invaginations of the navicular bone are associated with pathology of both the navicular apparatus and distal interphalangeal joint when evaluated using magnetic resonance imaging

ACVS Surgery Summit. Presented at the ACVS Surgery Summit.

Changes In Serum, But Not Synovial Fluid, Levels of Inflammatory Biomarker MCP-1 Are Correlated With Cartilage T2* Relaxation Times After ACL Injury In A Juvenile Porcine Model

ORS Annual Meeting. Presented at the ORS Annual Meeting.

Defining the Inflammatory Cytokine Profile In Acute Tendon Injury to Enhance Mesenchymal Stem Cell Therapy

NCSU Litwack Research Day 2022. Poster presented at the NCSU Litwack Research Day 2022.

Defining the profile: Characterizing cytokines in tendon injury to improve clinical therapy

Journal of Immunology and Regenerative Medicine, 16, 100059.

Demystifying stem cells and biologics in the joint disease challenge - emphasis on the stifle

American College of Veterinary Surgeons Surgery Summit. Presented at the American College of Veterinary Surgeons Surgery Summit, Portland, OR.

Dynamic Provisional Matrix Colloidal-Composite Scaffolds for Partial Anterior Cruciate Ligament Tears

Society for Biomaterials Annual Meeting. Poster presented at the Society for Biomaterials Annual Meeting.

Effect of gentamicin on CD3+ T-lymphocyte proliferation and cell viability for treatment of recurrent uveitis in horses: a pilot study

International Equine Ophthalmology Consortium. Presented at the International Equine Ophthalmology Consortium.

Effect of serum deprivation on viability and proliferation of equine tenocytes

National Veterinary Scholars Symposium. Poster presented at the National Veterinary Scholars Symposium.

Evaluation of Safety and Efficacy of Platelet-like Particles in Trauma Models

Society for Biomaterials Annual Meeting. Poster presented at the Society for Biomaterials Annual Meeting.

Evaluation of poor performance in the sport horse - axial skeleton

Maryland Delaware Veterinary Medical Association Annual Summer Conference. Presented at the Maryland Delaware Veterinary Medical Association Annual Summer Conference, Ocean City, MD.

Fibrin Based Drug Delivery System for Treatment of Staphylococcus Aureus Biofilms

Biomedical Engineering Society Annual Meeting. Presented at the Biomedical Engineering Society Annual Meeting.

Fighting Fibrin with Fibrin: Fibrin Based Nanoparticle Incorporation into S. aureus Biofilms

Biomedical Engineering Society Annual Meeting. Presented at the Biomedical Engineering Society Annual Meeting.

Functional Outcomes After Partial ACL Injury in A Skeletally Immature Porcine Model Differ by Injury Location

Summer Biomechanics, Bioengineering and Biotransport Conference. Presented at the Summer Biomechanics, Bioengineering and Biotransport Conference 2022.

Inflammation in Tendon Injury Enhances Mesenchymal Stem Cell Expression of Reparative Genes

ORS Tendon Section Conference. Poster presented at the ORS Tendon Section Conference.

Interleukin-1β in tendon injury enhances reparative gene and protein expression in mesenchymal stem cells

Frontiers in Veterinary Science, 9.

Interleukin-1 Present in Tendon Injury Enhances the Reparative Function of Mesenchymal Stem Cells

ACVS Surgery Summit. Presented at the ACVS Surgery Summit.

Leveraging MRI characterization of longitudinal tears of the deep digital flexor tendon in horses using machine learning

ELKhamary, A. N., Keenihan, E. K., Schnabel, L. V., Redding, W. R., & Schumacher, J. (2022, April 12). Veterinary Radiology & Ultrasound, Vol. 4.

Non‐steroidal anti‐inflammatory drugs in equine orthopaedics

Equine Veterinary Journal, 54(4), 636–648.

Point-of-care-biologics for the treatment of musculoskeletal injuries

Maryland Delaware Veterinary Medical Association Annual Summer Conference. Presented at the Maryland Delaware Veterinary Medical Association Annual Summer Conference, Ocean City, MD.

Polyacrylamide Hydrogels (PAAGs) for intra-articular therapy: How they work and how they fit in

2022 Hambletonian CE Seminar. Presented at the 2022 Hambletonian CE Seminar, East Rutherford, NJ.

Potent Activity of Ertapenem Plus Cefazolin Within Staphylococcal Biofilms: A Contributing Factor in the Treatment of Methicillin-Susceptible Staphylococcus aureus Endocarditis

Open Forum Infectious Diseases, 9(5).

Principles behind and clinical use of biologic therapies in veterinary medicine

American Association of Equine Veterinary Technicians and Assistants Convention. Presented at the American Association of Equine Veterinary Technicians and Assistants Convention, San Antonio, TX.

Rehabilitation and monitoring of tendon and ligament injuries

Maryland Delaware Veterinary Medical Association Annual Summer Conference. Presented at the Maryland Delaware Veterinary Medical Association Annual Summer Conference, Ocean City, MD.

Shearing Tenocytes on Direct-write Near-field Electrospun Gelatin Fibers: Towards a Tendon-on-chip

Biomedical Engineering Society Annual Meeting. Poster presented at the Biomedical Engineering Society Annual Meeting.

TGF-β2 enhances expression of equine bone marrow-derived mesenchymal stem cell paracrine factors with known associations to tendon healing

Stem Cell Research & Therapy, 13(1).

TLR-activated mesenchymal stromal cell therapy and antibiotics to treat multi-drug resistant Staphylococcal septic arthritis in an equine model

Annals of Translational Medicine, 10(21), 1157–1157.

Tendon sheath masses – What are the differential diagnoses and what diagnostics are needed?

Equine Veterinary Education, 35(2), 74–76.

Use of stem cells for the treatment of musculoskeletal injuries: what type, how, and when?

Maryland Delaware Veterinary Medical Association Annual Summer Conference. Presented at the Maryland Delaware Veterinary Medical Association Annual Summer Conference, Ocean City, MD.

ACL Injury Impacts Long-Term Knee Function and Tissue Remodeling in a Skeletally Immature Porcine Model

TARC Research Day. Presented at the TARC Research Day.

Adeno-Associated Virus-Mediated Overexpression of Interleukin-10 Affects the Immunomodulatory Properties of Equine Bone Marrow-Derived Mesenchymal Stem Cells

Cameron, A. D., Even, K. M., Linardi, R. L., Berglund, A. K., Schnabel, L. V., Engiles, J. B., & Ortved, K. F. (2021, April 12). Human Gene Therapy, Vol. 32, pp. 907–918.

Characterizing the cytokine environment in acute tendon injury to enhance stem cell therapy

American Association of Equine Practitioners (AAEP) Convention and Trade Show. Presented at the American Association of Equine Practitioners (AAEP) Convention and Trade Show.

Corrigendum to “Effects of continuous passage on the immunomodulator properties of equine bone marrow-derived mesenchymal stem cells in vitro” [Vet. Immunol. Immunopathol. 234 (2021) 110203]

Connard, S. S., Linardi, R. L., Even, K. M., Berglund, A. K., Schnabel, L. V., & Ortved, K. F. (2021, October 28). Veterinary Immunology and Immunopathology, Vol. 242.

Defining the Inflammatory Cytokine Profile in Acute Tendon Injury to Enhance Mesenchymal Stem Cell Therapy

National Veterinary Scholars Symposium. Presented at the National Veterinary Scholars Symposium.

Effect of TFG-b2 on MHC-related gene expression in equine mesenchymal stem cells

NCSU Litwack Research Day. Poster presented at the NCSU Litwack Research Day.

Effects of continuous passage on the immunomodulatory properties of equine bone marrow-derived mesenchymal stem cells in vitro

Veterinary Immunology and Immunopathology, 234, 110203.

Fibrin Based Nanoparticles for S. aureus Infection and Biofilm Treatment

Biomedical Engineering Society Meeting. Presented at the Biomedical Engineering Society Meeting.

Frontiers in Athletic Rehabilitation: What is Translatable to the Horse

Association of Equine Practitioners (AAEP) Convention and Trade Show. Presented at the Association of Equine Practitioners (AAEP) Convention and Trade Show, Nashville, TN.

Gene expression in equine bone marrow-derived mesenchymal stem cells

13th Dorothy Russell Havemeyer International Horse Genome Workshop. Presented at the 13th Dorothy Russell Havemeyer International Horse Genome Workshop.

Pathology in Practice

Journal of the American Veterinary Medical Association, 258(9), 961–964.

TGF-β2 Reduces the Cell-Mediated Immunogenicity of Equine MHC-Mismatched Bone Marrow-Derived Mesenchymal Stem Cells Without Altering Immunomodulatory Properties

Frontiers in Cell and Developmental Biology, 9.

Temporal assessment of the cytokine environment of acute tendon injury in an equine model by use of a novel ultrafiltrate probe

NCSU Litwack Research Day. Presented at the NCSU Litwack Research Day.

Therapeutic use of stem cells in horses: which type, how, and when?

10th International Symposium of the Athletic Horse (SIMCAV). Presented at the 10th International Symposium of the Athletic Horse (SIMCAV), Brazil.

Time Course of Inflammatory Biomarker MCP-1 and Cartilage T2* after ACL Injury in a Juvenile Porcine Model Analysis

TARC Research Day. Presented at the TARC Research Day.

What do we know about Immunomodulatory effect of stem cells for joint disease?10th

International Symposium of the Athletic Horse (SIMCAV). Presented at the International Symposium of the Athletic Horse (SIMCAV), Brazil.

A pooled equine platelet-rich plasma lysate biologic as a novel disease-modifying osteoarthritis therapy

American Association of Equine Practitioners (AAEP) Virtual Convention and Trade Show. Presented at the American Association of Equine Practitioners (AAEP) Virtual Convention and Trade Show.

Advances in the diagnosis of tendon and ligament injuries

Northeast Association of Equine Practitioners (NAEP) Symposium. Presented at the Northeast Association of Equine Practitioners (NAEP) Symposium.

Allorecognition of Mesenchymal Stem Cells is Dependent on Major Histocompatibility Complex Haplotype

Presented at the Abstracts of the 47th Annual Conference of the Veterinary Orthopedic Society.

Cross-matching of allogeneic mesenchymal stromal cells eliminates recipient immune targeting

Rowland, A. L., Miller, D., Berglund, A., Schnabel, L. V., Levine, G. J., Antczak, D. F., & Watts, A. E. (2020, December 25). Stem Cells Translational Medicine, Vol. 10, pp. 694–710.