Luo Xiao

Also known as: Luo

https://orcid.org/0000-0001-8707-0914

Functional data analysis; Longitudinal data analysis; Smoothing; Semiparametric regression; high di

I am a statistician interested in developing functional data methods for applications in biostatistics including neuroimaging, wearable computing and growth data.

Works (42)

Updated: November 9th, 2023 05:00

2023 journal article

BAYESIAN INFERENCE AND DYNAMIC PREDICTION FOR MULTIVARIATE LONGITUDINAL AND SURVIVAL DATA

ANNALS OF APPLIED STATISTICS, 17(3), 2574–2595.

By: H. Zou*, D. Zeng*, L. Xiao n & S. Luo*

co-author countries: United States of America 🇺🇸
author keywords: Alzheimer's disease; multivariate longitudinal data; functional mixed model; joint model; Bayesian method; dynamic prediction
Sources: Web Of Science, ORCID
Added: November 6, 2023

2023 article

Latent factor model for multivariate functional data

Li, R., & Xiao, L. (2023, September 4). BIOMETRICS, Vol. 9.

By: R. Li n & L. Xiao n

co-author countries: United States of America 🇺🇸
author keywords: covariance function; fPCA; functional data; model identifiability; penalized splines
Sources: Web Of Science, ORCID
Added: September 11, 2023

2023 article

Multivariate functional mixed model with MRI data: An application to Alzheimer's disease

Zou, H., Xiao, L., Zeng, D., & Luo, S. (2023, February 20). STATISTICS IN MEDICINE, Vol. 2.

By: H. Zou*, L. Xiao n, D. Zeng* & S. Luo*

co-author countries: United States of America 🇺🇸
author keywords: Alzheimer's disease; Bayesian method; dynamic prediction; functional regression; magnetic resonance imaging
MeSH headings : Humans; Alzheimer Disease; Magnetic Resonance Imaging; Neuroimaging; Brain / diagnostic imaging; Brain / pathology; Disease Progression; Cognitive Dysfunction / diagnostic imaging
Sources: Web Of Science, ORCID
Added: March 20, 2023

2022 article

Fast Multilevel Functional Principal Component Analysis

Cui, E., Li, R., Crainiceanu, C. M., & Xiao, L. (2022, October 7). JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS, Vol. 10.

By: E. Cui*, R. Li n, C. Crainiceanu* & L. Xiao n

co-author countries: United States of America 🇺🇸
author keywords: Functional principal component analysis; Mixed model equations; Multilevel models
Sources: Web Of Science, ORCID
Added: October 24, 2022

2022 article

Fixed-effects inference and tests of correlation for longitudinal functional data

Li, R., Xiao, L., Smirnova, E., Cui, E., Leroux, A., & Crainiceanu, C. M. (2022, May 1). STATISTICS IN MEDICINE, Vol. 5.

By: R. Li n, L. Xiao n, E. Smirnova*, E. Cui*, A. Leroux* & C. Crainiceanu*

co-author countries: United States of America 🇺🇸
author keywords: accelerometry data; covariance function; hypothesis test; mixed effects model
MeSH headings : Computer Simulation; Exercise; Humans; Longitudinal Studies; Research Design
Sources: Web Of Science, ORCID
Added: May 10, 2022

2022 article

Functional data analysis for longitudinal data with informative observation times

Weaver, C., Xiao, L., & Lu, W. (2022, March 28). BIOMETRICS, Vol. 3.

By: C. Weaver n, L. Xiao n & W. Lu n

co-author countries: United States of America 🇺🇸
author keywords: functional data analysis; informative observation times; longitudinal data; penalized splines
MeSH headings : Models, Statistical; Longitudinal Studies; Computer Simulation
Sources: Web Of Science, ORCID
Added: February 22, 2022

2022 journal article

Joint model for survival and multivariate sparse functional data with application to a study of Alzheimer's Disease

BIOMETRICS, 78(2), 435–447.

By: C. Li*, L. Xiao n & S. Luo*

co-author countries: United States of America 🇺🇸
author keywords: EM algorithm; functional mixed model; multivariate longitudinal data; smoothing; survival
MeSH headings : Alzheimer Disease / diagnostic imaging; Databases, Factual; Disease Progression; Humans; Neuroimaging / methods
Sources: Web Of Science, ORCID
Added: March 1, 2021

2022 article

Two-stage linked component analysis for joint decomposition of multiple biologically related data sets

Chen, H., Caffo, B., Stein-O'Brien, G., Liu, J., Langmead, B., Colantuoni, C., & Xiao, L. (2022, March 31). BIOSTATISTICS, Vol. 3.

co-author countries: United States of America 🇺🇸
author keywords: Integrative methods; Joint decomposition; Low rank models; Multiview data; Principal component analysis
MeSH headings : Computer Simulation; Humans; Transcriptome
Sources: Web Of Science, ORCID
Added: May 2, 2022

2021 journal article

A functional mixed model for scalar on function regression with application to a functional MRI study

BIOSTATISTICS, 22(3), 439–454.

By: W. Ma n, L. Xiao n, B. Liu n & M. Lindquist*

co-author countries: United States of America 🇺🇸
author keywords: fMRI; Functional data analysis; Functional mixed model; Functional principal component; Repeated measurements; Variance component testing
MeSH headings : Brain / diagnostic imaging; Computer Simulation; Humans; Magnetic Resonance Imaging; Principal Component Analysis
Sources: Web Of Science, ORCID
Added: January 15, 2020

2021 journal article

Fetal growth velocity standards from the Fetal Growth Longitudinal Study of the INTERGROWTH-21 st Project

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 224(2).

By: E. Ohuma*, J. Villar*, Y. Feng n, L. Xiao n, L. Salomon*, F. Barros*, L. Ismail*, W. Stones* ...

co-author countries: United Arab Emirates 🇦🇪 Brazil 🇧🇷 Canada 🇨🇦 China 🇨🇳 France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Italy 🇮🇹 Kenya 🇰🇪 Oman 🇴🇲 United States of America 🇺🇸
MeSH headings : Abdomen / diagnostic imaging; Abdomen / embryology; Adult; Crown-Rump Length; Female; Femur / diagnostic imaging; Femur / embryology; Fetal Development; Gestational Age; Growth Charts; Head / diagnostic imaging; Head / embryology; Humans; Infant, Newborn; Internationality; Longitudinal Studies; Male; Pregnancy; Ultrasonography, Prenatal; Young Adult
Sources: Web Of Science, ORCID
Added: March 15, 2021

2021 article

Single-index models with functional connectivity network predictors

Weaver, C., Xiao, L., & Lindquist, M. A. (2021, May 5). BIOSTATISTICS, Vol. 5.

By: C. Weaver n, L. Xiao n & M. Lindquist*

co-author countries: United States of America 🇺🇸
author keywords: fMRI; Networks; Nonparametric regression; Penalized splines; Sparsity
MeSH headings : Humans; Nerve Net / diagnostic imaging; Nerve Net / physiology; Connectome / methods; Magnetic Resonance Imaging / methods; Brain / diagnostic imaging; Brain / physiology; Computer Simulation
Sources: Web Of Science, ORCID
Added: July 5, 2021

2020 journal article

Asymptotic properties of penalized splines for functional data

BERNOULLI, 26(4), 2847–2875.

By: L. Xiao*

author keywords: L-2 convergence; functional data analysis; nonparametric regression; penalized splines; uniform convergence
Sources: Web Of Science, ORCID
Added: September 14, 2020

2020 journal article

Correlation models for monitoring fetal growth

STATISTICAL METHODS IN MEDICAL RESEARCH, 29(10), 2795–2813.

By: Y. Feng n, L. Xiao n, C. Li n, S. Chen n & E. Ohuma*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: Fetal health; longitudinal study; correlation; reference chart
MeSH headings : Female; Femur / diagnostic imaging; Fetal Development; Gestational Age; Humans; Longitudinal Studies; Pregnancy; Ultrasonography, Prenatal
Sources: Web Of Science, ORCID
Added: April 20, 2020

2020 journal article

Fast covariance estimation for multivariate sparse functional data

STAT, 9(1).

By: C. Li n, L. Xiao n & S. Luo*

co-author countries: United States of America 🇺🇸
author keywords: bivariate smoothing; covariance function; functional principal component analysis; longitudinal data; multivariate functional data; prediction
Sources: Web Of Science, ORCID
Added: March 1, 2021

2020 journal article

Uniform convergence of penalized splines

STAT, 9(1).

By: L. Xiao n & Z. Nan*

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: nonparametric regression; penalized splines; rate optimality; uniform convergence
Sources: Web Of Science, ORCID
Added: March 1, 2021

2019 journal article

A smoothing-based goodness-of-fit test of covariance for functional data

BIOMETRICS, 75(2), 562–571.

By: S. Chen n, L. Xiao n & A. Staicu n

co-author countries: United States of America 🇺🇸
author keywords: functional data analysis; Functional principal components analysis; hypothesis testing; linear mixed effects models; longitudinal data analysis
MeSH headings : Analysis of Variance; Computer Simulation; Data Interpretation, Statistical; Humans; Longitudinal Studies; Models, Statistical
Sources: Web Of Science, ORCID
Added: September 23, 2019

2019 journal article

Asymptotic theory of penalized splines

ELECTRONIC JOURNAL OF STATISTICS, 13(1), 747–794.

By: L. Xiao*

author keywords: Nonparametric regression; penalized splines; L-infinity convergence; L-2 convergence; local asymptotics; rate optimality
Sources: Web Of Science, ORCID
Added: May 13, 2019

2019 journal article

Optimal design for classification of functional data

Canadian Journal of Statistics, 12.

By: C. Li n & L. Xiao n

co-author countries: United States of America 🇺🇸
author keywords: Covariance function; linear discriminant analysis; longitudinal data
Source: ORCID
Added: January 15, 2020

2019 journal article

Using data from multiple studies to develop a child growth correlation matrix

STATISTICS IN MEDICINE, 38(19), 3540–3554.

By: C. Anderson*, L. Xiao n & W. Checkley*

co-author countries: Australia 🇦🇺 United States of America 🇺🇸
author keywords: child health; correlation; growth; SDS
MeSH headings : Body Height / physiology; Body Weight / physiology; Child; Child Development / physiology; Child, Preschool; Female; Growth / physiology; Growth Charts; Humans; Longitudinal Studies; Male; Meta-Analysis as Topic
Sources: Web Of Science, ORCID
Added: August 5, 2019

2018 journal article

A joint design for functional data with application to scheduling ultrasound scans

COMPUTATIONAL STATISTICS & DATA ANALYSIS, 122, 101–114.

By: S. Park*, L. Xiao n, J. Willbur*, A. Staicu n & N. Jumbe*

co-author countries: United States of America 🇺🇸
author keywords: Covariance function; Functional data analysis; Fetal growth; Longitudinal data; Prediction
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Asymptotics of bivariate penalised splines

Journal of Nonparametric Statistics, 31(2), 289–314.

By: L. Xiao n

co-author countries: United States of America 🇺🇸
author keywords: B-splines; P-splines; regression spline; smoothing; tensor product splines
Sources: ORCID, Crossref
Added: January 15, 2020

2018 journal article

Dynamic prediction in functional concurrent regression with an application to child growth

STATISTICS IN MEDICINE, 37(8), 1376–1388.

co-author countries: United States of America 🇺🇸
author keywords: covariance function; face; fPCA; longitudinal data; mixed effects; penalized splines; sparse functional data
MeSH headings : Anthropometry; Body Height; Body Weight; Child Development; Child, Preschool; Computer Simulation; Data Interpretation, Statistical; Female; Forecasting / methods; Growth; Growth Charts; Humans; Infant; Infant, Newborn; Male; Peru; Regression Analysis
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Fast covariance estimation for sparse functional data

STATISTICS AND COMPUTING, 28(3), 511–522.

By: L. Xiao n, C. Li n, W. Checkley* & C. Crainiceanu*

co-author countries: United States of America 🇺🇸
author keywords: Bivariate smoothing; FACEs; fPCA
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 article

Fast covariance estimation for sparse functional data (vol 28, pg 511, 2017)

Xiao, L., Li, C., Checkley, W., & Crainiceanu, C. (2018, May). STATISTICS AND COMPUTING, Vol. 28, pp. 523–523.

By: L. Xiao n, C. Li n, W. Checkley* & C. Crainiceanu*

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Novel metrics for growth model selection

Emerging Themes in Epidemiology, 15.

By: M. Grigsby, J. Di, A. Leroux, V. Zipunnikov, L. Xiao, C. Crainiceanu, W. Checkley

Source: NC State University Libraries
Added: August 6, 2018

2018 personal communication

Total volume of physical activity: TAC, TLAC or TAC(lambda)

Varma, V. R., Dey, D., Leroux, A., Di, J., Urbanek, J., Xiao, L., & Zipunnikov, V. (2018, January).

co-author countries: United States of America 🇺🇸
author keywords: Physical activity
MeSH headings : Accelerometry; Exercise
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

AN ACTIVITY INDEX FOR RAW ACCELEROMETRY DATA AND ITS APPLICATION IN OLDER ADULTS

Innovation in Aging, 1(suppl_1), 1239–1239.

By: J. Bai*, C. Di*, L. Xiao n, K. Evenson*, A. LaCroix*, C. Crainiceanu*, D. Buchner*

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: January 15, 2020

2017 journal article

Re-evaluating the effect of age on physical activity over the lifespan

PREVENTIVE MEDICINE, 101, 102–108.

co-author countries: United States of America 🇺🇸
author keywords: Accelerometer; Diurnal; Lifespan; NHANES; Physical activity; Sex differences; Gender
MeSH headings : Adolescent; Aged; Aging / physiology; Cross-Sectional Studies; Exercise; Female; Humans; Male; Nutrition Surveys; Sedentary Behavior; Sex Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Simple fixed-effects inference for complex functional models

Biostatistics, 19(2), 137–152.

By: S. Park n, A. Staicu n, L. Xiao n & C. Crainiceanu*

co-author countries: United States of America 🇺🇸
author keywords: Bootstrap/resampling; Functional data; Measurement error; Smoothing and nonparametric regression
MeSH headings : Accelerometry / statistics & numerical data; Aged; Aged, 80 and over; Aging / physiology; Baltimore; Data Interpretation, Statistical; Exercise / physiology; Female; Humans; Longitudinal Studies; Middle Aged; Models, Statistical
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Two-way principal component analysis for matrix-variate data, with an application to functional magnetic resonance imaging data

Biostatistics (Oxford, England), 18(2), 214–229.

By: L. Huang, P. Reiss, L. Xiao, V. Zipunnikov, M. Lindquist & C. Crainiceanu

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

An Activity Index for Raw Accelerometry Data and Its Comparison with Other Activity Metrics

PLOS ONE, 11(8), 1–14.

co-author countries: United States of America 🇺🇸
MeSH headings : Accelerometry / instrumentation; Accelerometry / methods; Accelerometry / standards; Aged; Aged, 80 and over; Energy Metabolism; Exercise; Female; Humans; Middle Aged; ROC Curve; Software
Sources: ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

CollocInfer: Collocation Inference in Differential Equation Models

Journal of Statistical Software, 75(2).

By: G. Hooker, J. Ramsay & L. Xiao*

author keywords: differential equation; collocation; profiled estimation; smoothing
Sources: ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

Convex Banding of the Covariance Matrix

Journal of the American Statistical Association, 111(514), 834–845.

By: J. Bien, F. Bunea & L. Xiao*

author keywords: Adaptive; Hierarchical group lasso; High-dimensional; Structured sparsity
Sources: ORCID, Crossref
Added: January 15, 2020

2016 journal article

Fast covariance estimation for high-dimensional functional data

Statistics and Computing, 26(1-2), 409–421.

By: L. Xiao*, V. Zipunnikov*, D. Ruppert* & C. Crainiceanu*

co-author countries: United States of America 🇺🇸
author keywords: FACE; fPCA; Penalized splines; Sandwich smoother; Smoothing; Singular value decomposition
Sources: Crossref, ORCID
Added: January 15, 2020

2016 journal article

Movement prediction using accelerometers in a human population

BIOMETRICS, 72(2), 513–524.

co-author countries: Denmark 🇩🇰 Netherlands 🇳🇱 United States of America 🇺🇸
author keywords: Accelerometer; Activity type; Movelets; Prediction
MeSH headings : Accelerometry / statistics & numerical data; Activities of Daily Living; Forecasting; Humans; Movement / physiology; Posture; Supervised Machine Learning
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Two-way principal component analysis for matrix-variate data, with an application to functional magnetic resonance imaging data

Biostatistics, 8, kxw040.

By: L. Huang*, P. Reiss, L. Xiao n, V. Zipunnikov*, M. Lindquist* & C. Crainiceanu*

co-author countries: United States of America 🇺🇸
author keywords: fMRI; Latent process modeling; Matrix-variate; Principal component analysis; Separability
MeSH headings : Brain Mapping / methods; Humans; Magnetic Resonance Imaging / methods; Principal Component Analysis
Source: ORCID
Added: January 15, 2020

2015 journal article

On tests of activation map dimensionality for fMRI-based studies of learning

Frontiers in Neuroscience, 9.

By: J. Yang*, L. Shmuelof*, L. Xiao*, J. Krakauer* & B. Caffo*

co-author countries: Israel 🇮🇱 United States of America 🇺🇸
author keywords: canonical variates analysis; cognitive learning; BOLD fMRI; statistical parametric mapping; interaction test
Source: ORCID
Added: January 15, 2020

2015 journal article

On the sample covariance matrix estimator of reduced effective rank population matrices, with applications to fPCA

Bernoulli, 21(2), 1200–1230.

By: F. Bunea & L. Xiao*

author keywords: covariance matrix; eigenvalue; eigenvector; fPCA; high dimensions; minimax rate; optimal rate of convergence; PCA; scree plot; sparsity
Source: ORCID
Added: January 15, 2020

2014 journal article

Bayesian Models for Multiple Outcomes in Domains With Application to the Seychelles Child Development Study

Journal of the American Statistical Association, 109(505), 1–10.

By: L. Xiao*, S. Thurston*, D. Ruppert*, T. Love* & P. Davidson*

co-author countries: United States of America 🇺🇸
author keywords: Bayesian variable selection; Latent variable model; Markov chain Monte Carlo; Methylmercury; Sparsity
Source: ORCID
Added: January 15, 2020

2014 journal article

Learning regulatory programs by threshold SVD regression

Proceedings of the National Academy of Sciences, 111(44), 15675–15680.

By: X. Ma, L. Xiao* & W. Wong*

co-author countries: United States of America 🇺🇸
author keywords: regulatory program; SVD; sparse; multivariate; regression
MeSH headings : Computer Simulation; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs / biosynthesis; MicroRNAs / genetics; Models, Genetic; Neoplasms / genetics; Neoplasms / metabolism; RNA, Neoplasm / biosynthesis; RNA, Neoplasm / genetics
Source: ORCID
Added: January 15, 2020

2014 journal article

Quantifying the lifetime circadian rhythm of physical activity: a covariate-dependent functional approach

Biostatistics, 16(2), 352–367.

By: L. Xiao*, L. Huang*, J. Schrack*, L. Ferrucci*, V. Zipunnikov* & C. Crainiceanu*

co-author countries: United States of America 🇺🇸
author keywords: Accelerometer; Bivariate smoothing; Covariance; Sandwich smoother; Trivariate smoothing
MeSH headings : Accelerometry / statistics & numerical data; Adult; Aged; Aged, 80 and over; Aging / physiology; Circadian Rhythm / physiology; Female; Humans; Male; Middle Aged; Motor Activity / physiology; Principal Component Analysis; Sex Factors
Source: ORCID
Added: January 15, 2020

2013 journal article

Fast bivariateP-splines: the sandwich smoother

Journal of the Royal Statistical Society: Series B (Statistical Methodology), 75(3), 577–599.

By: L. Xiao*, Y. Li* & D. Ruppert*

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: Asymptotics; Bivariate smoothing; Covariance function; Generalized linear array model; Non-parametric regression; Penalized splines; Sandwich smoother; Thin plate splines
Source: ORCID
Added: January 15, 2020

Employment

Updated: November 27th, 2017 22:41

2015 - present

North Carolina State University Raleigh, NC, US
Assistant Professor Department of Statistics

2012 - 2015

Johns Hopkins University Baltimore, MD, US
Postdoctoral Fellow Deparment of Biostatistics

Education

Updated: November 27th, 2017 22:38

2007 - 2012

Cornell University Ithaca, NY, US
PhD Department of Statistics

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