Luo Xiao

Also known as: Luo

https://orcid.org/0000-0001-8707-0914

Functional data analysis; Longitudinal data analysis; Smoothing; Semiparametric regression; high di

I am a statistician interested in developing functional data methods for applications in biostatistics including neuroimaging, wearable computing and growth data.

Works (40)

Updated: April 11th, 2023 10:13

2023 article

Multivariate functional mixed model with MRI data: An application to Alzheimer's disease

Zou, H., Xiao, L., Zeng, D., & Luo, S. (2023, February 20). STATISTICS IN MEDICINE, Vol. 2.

By: H. Zou*, L. Xiao, D. Zeng* & S. Luo*

author keywords: Alzheimer's disease; Bayesian method; dynamic prediction; functional regression; magnetic resonance imaging
Sources: Web Of Science, ORCID
Added: March 20, 2023

2022 article

Fast Multilevel Functional Principal Component Analysis

Cui, E., Li, R., Crainiceanu, C. M., & Xiao, L. (2022, October 7). JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS, Vol. 10.

By: E. Cui*, R. Li, C. Crainiceanu* & L. Xiao

author keywords: Functional principal component analysis; Mixed model equations; Multilevel models
Sources: Web Of Science, ORCID
Added: October 24, 2022

2022 article

Fixed-effects inference and tests of correlation for longitudinal functional data

Li, R., Xiao, L., Smirnova, E., Cui, E., Leroux, A., & Crainiceanu, C. M. (2022, May 1). STATISTICS IN MEDICINE, Vol. 5.

By: R. Li, L. Xiao, E. Smirnova*, E. Cui*, A. Leroux* & C. Crainiceanu*

author keywords: accelerometry data; covariance function; hypothesis test; mixed effects model
Sources: Web Of Science, ORCID
Added: May 10, 2022

2022 article

Functional data analysis for longitudinal data with informative observation times

Weaver, C., Xiao, L., & Lu, W. (2022, March 28). BIOMETRICS, Vol. 3.

By: C. Weaver, L. Xiao & W. Lu

author keywords: functional data analysis; informative observation times; longitudinal data; penalized splines
Sources: Web Of Science, ORCID
Added: February 22, 2022

2022 journal article

Joint model for survival and multivariate sparse functional data with application to a study of Alzheimer's Disease

BIOMETRICS, 78(2), 435–447.

By: C. Li, L. Xiao & S. Luo*

author keywords: EM algorithm; functional mixed model; multivariate longitudinal data; smoothing; survival
Sources: Web Of Science, ORCID
Added: March 1, 2021

2022 article

Two-stage linked component analysis for joint decomposition of multiple biologically related data sets

Chen, H., Caffo, B., Stein-O'Brien, G., Liu, J., Langmead, B., Colantuoni, C., & Xiao, L. (2022, March 31). BIOSTATISTICS, Vol. 3.

By: H. Chen*, B. Caffo*, G. Stein-O'Brien*, J. Liu*, B. Langmead*, C. Colantuoni*, L. Xiao

author keywords: Integrative methods; Joint decomposition; Low rank models; Multiview data; Principal component analysis
Sources: Web Of Science, ORCID
Added: May 2, 2022

2021 journal article

A functional mixed model for scalar on function regression with application to a functional MRI study

BIOSTATISTICS, 22(3), 439–454.

By: W. Ma n, L. Xiao, B. Liu & M. Lindquist*

author keywords: fMRI; Functional data analysis; Functional mixed model; Functional principal component; Repeated measurements; Variance component testing
Sources: Web Of Science, ORCID
Added: January 15, 2020

2021 journal article

Fetal growth velocity standards from the Fetal Growth Longitudinal Study of the INTERGROWTH-21 st Project

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 224(2).

By: E. Ohuma*, J. Villar*, Y. Feng n, L. Xiao, L. Salomon*, F. Barros*, L. Ismail*, W. Stones* ...

Sources: Web Of Science, ORCID
Added: March 15, 2021

2021 article

Single-index models with functional connectivity network predictors

Weaver, C., Xiao, L., & Lindquist, M. A. (2021, May 5). BIOSTATISTICS, Vol. 5.

By: C. Weaver, L. Xiao & M. Lindquist*

author keywords: fMRI; Networks; Nonparametric regression; Penalized splines; Sparsity
Sources: Web Of Science, ORCID
Added: July 5, 2021

2020 journal article

Asymptotic properties of penalized splines for functional data

BERNOULLI, 26(4), 2847–2875.

By: L. Xiao

author keywords: L-2 convergence; functional data analysis; nonparametric regression; penalized splines; uniform convergence
Sources: Web Of Science, ORCID
Added: September 14, 2020

2020 journal article

Correlation models for monitoring fetal growth

STATISTICAL METHODS IN MEDICAL RESEARCH, 29(10), 2795–2813.

By: Y. Feng n, L. Xiao, C. Li, S. Chen & E. Ohuma*

author keywords: Fetal health; longitudinal study; correlation; reference chart
Sources: Web Of Science, ORCID
Added: April 20, 2020

2020 journal article

Fast covariance estimation for multivariate sparse functional data

STAT, 9(1).

By: C. Li, L. Xiao & S. Luo*

author keywords: bivariate smoothing; covariance function; functional principal component analysis; longitudinal data; multivariate functional data; prediction
Sources: Web Of Science, ORCID
Added: March 1, 2021

2020 journal article

Uniform convergence of penalized splines

STAT, 9(1).

By: L. Xiao & Z. Nan*

author keywords: nonparametric regression; penalized splines; rate optimality; uniform convergence
Sources: Web Of Science, ORCID
Added: March 1, 2021

2019 journal article

A smoothing-based goodness-of-fit test of covariance for functional data

BIOMETRICS, 75(2), 562–571.

By: S. Chen, L. Xiao & A. Staicu

author keywords: functional data analysis; Functional principal components analysis; hypothesis testing; linear mixed effects models; longitudinal data analysis
Sources: Web Of Science, ORCID
Added: September 23, 2019

2019 journal article

Asymptotic theory of penalized splines

ELECTRONIC JOURNAL OF STATISTICS, 13(1), 747–794.

By: L. Xiao

author keywords: Nonparametric regression; penalized splines; L-infinity convergence; L-2 convergence; local asymptotics; rate optimality
Sources: Web Of Science, ORCID
Added: May 13, 2019

2019 journal article

Optimal design for classification of functional data

Canadian Journal of Statistics, 12.

By: C. Li n & L. Xiao

author keywords: Covariance function; linear discriminant analysis; longitudinal data
Source: ORCID
Added: January 15, 2020

2019 journal article

Using data from multiple studies to develop a child growth correlation matrix

STATISTICS IN MEDICINE, 38(19), 3540–3554.

By: C. Anderson*, L. Xiao & W. Checkley*

author keywords: child health; correlation; growth; SDS
Sources: Web Of Science, ORCID
Added: August 5, 2019

2018 journal article

A joint design for functional data with application to scheduling ultrasound scans

COMPUTATIONAL STATISTICS & DATA ANALYSIS, 122, 101–114.

By: S. Park*, L. Xiao, J. Willbur*, A. Staicu & N. Jumbe*

author keywords: Covariance function; Functional data analysis; Fetal growth; Longitudinal data; Prediction
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Asymptotics of bivariate penalised splines

Journal of Nonparametric Statistics, 31(2), 289–314.

By: L. Xiao

author keywords: B-splines; P-splines; regression spline; smoothing; tensor product splines
Sources: ORCID, Crossref
Added: January 15, 2020

2018 journal article

Dynamic prediction in functional concurrent regression with an application to child growth

STATISTICS IN MEDICINE, 37(8), 1376–1388.

By: A. Leroux*, L. Xiao, C. Crainiceanu* & W. Checkley*

author keywords: covariance function; face; fPCA; longitudinal data; mixed effects; penalized splines; sparse functional data
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Fast covariance estimation for sparse functional data

STATISTICS AND COMPUTING, 28(3), 511–522.

By: L. Xiao, C. Li, W. Checkley* & C. Crainiceanu*

author keywords: Bivariate smoothing; FACEs; fPCA
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 article

Fast covariance estimation for sparse functional data (vol 28, pg 511, 2017)

Xiao, L., Li, C., Checkley, W., & Crainiceanu, C. (2018, May). STATISTICS AND COMPUTING, Vol. 28, pp. 523–523.

By: L. Xiao, C. Li, W. Checkley* & C. Crainiceanu*

Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Novel metrics for growth model selection

Emerging Themes in Epidemiology, 15.

By: M. Grigsby, J. Di, A. Leroux, V. Zipunnikov, L. Xiao, C. Crainiceanu, W. Checkley

Source: NC State University Libraries
Added: August 6, 2018

2018 personal communication

Total volume of physical activity: TAC, TLAC or TAC(lambda)

Varma, V. R., Dey, D., Leroux, A., Di, J., Urbanek, J., Xiao, L., & Zipunnikov, V. (2018, January).

By: V. Varma*, D. Dey*, A. Leroux*, J. Di*, J. Urbanek*, L. Xiao, V. Zipunnikov*

author keywords: Physical activity
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

AN ACTIVITY INDEX FOR RAW ACCELEROMETRY DATA AND ITS APPLICATION IN OLDER ADULTS

Innovation in Aging, 1(suppl_1), 1239–1239.

By: J. Bai*, C. Di*, L. Xiao, K. Evenson*, A. LaCroix*, C. Crainiceanu, D. Buchner*

Source: ORCID
Added: January 15, 2020

2017 journal article

Re-evaluating the effect of age on physical activity over the lifespan

PREVENTIVE MEDICINE, 101, 102–108.

By: V. Varma*, D. Dey*, A. Leroux*, J. Di*, J. Urbanek*, L. Xiao, V. Zipunnikov*

author keywords: Accelerometer; Diurnal; Lifespan; NHANES; Physical activity; Sex differences; Gender
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Simple fixed-effects inference for complex functional models

Biostatistics, 19(2), 137–152.

By: S. Park n, A. Staicu, L. Xiao & C. Crainiceanu*

author keywords: Bootstrap/resampling; Functional data; Measurement error; Smoothing and nonparametric regression
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Two-way principal component analysis for matrix-variate data, with an application to functional magnetic resonance imaging data

Biostatistics (Oxford, England), 18(2), 214–229.

By: L. Huang, P. Reiss, L. Xiao, V. Zipunnikov, M. Lindquist & C. Crainiceanu

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

An Activity Index for Raw Accelerometry Data and Its Comparison with Other Activity Metrics

PLOS ONE, 11(8), 1–14.

By: J. Bai*, C. Di*, L. Xiao, K. Evenson*, A. LaCroix*, C. Crainiceanu*, D. Buchner*

Sources: ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

CollocInfer: Collocation Inference in Differential Equation Models

Journal of Statistical Software, 75(2).

By: G. Hooker, J. Ramsay & L. Xiao

author keywords: differential equation; collocation; profiled estimation; smoothing
Sources: ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

Convex Banding of the Covariance Matrix

Journal of the American Statistical Association, 111(514), 834–845.

By: J. Bien*, F. Bunea* & L. Xiao

author keywords: Adaptive; Hierarchical group lasso; High-dimensional; Structured sparsity
Sources: ORCID, Crossref
Added: January 15, 2020

2016 journal article

Fast covariance estimation for high-dimensional functional data

Statistics and Computing, 26(1-2), 409–421.

By: L. Xiao, V. Zipunnikov*, D. Ruppert* & C. Crainiceanu*

author keywords: FACE; fPCA; Penalized splines; Sandwich smoother; Smoothing; Singular value decomposition
Sources: Crossref, ORCID
Added: January 15, 2020

2016 journal article

Movement prediction using accelerometers in a human population

BIOMETRICS, 72(2), 513–524.

By: L. Xiao, B. He*, A. Koster*, P. Caserotti*, B. Lange-Maia*, N. Glynn*, T. Harris*, C. Crainiceanu*

author keywords: Accelerometer; Activity type; Movelets; Prediction
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Two-way principal component analysis for matrix-variate data, with an application to functional magnetic resonance imaging data

Biostatistics, 8, kxw040.

By: L. Huang*, P. Reiss, L. Xiao, V. Zipunnikov*, M. Lindquist* & C. Crainiceanu*

author keywords: fMRI; Latent process modeling; Matrix-variate; Principal component analysis; Separability
Source: ORCID
Added: January 15, 2020

2015 journal article

On tests of activation map dimensionality for fMRI-based studies of learning

Frontiers in Neuroscience, 9.

By: J. Yang, L. Shmuelof, L. Xiao, J. Krakauer & B. Caffo

author keywords: canonical variates analysis; cognitive learning; BOLD fMRI; statistical parametric mapping; interaction test
Source: ORCID
Added: January 15, 2020

2015 journal article

On the sample covariance matrix estimator of reduced effective rank population matrices, with applications to fPCA

Bernoulli, 21(2), 1200–1230.

By: F. Bunea & L. Xiao

author keywords: covariance matrix; eigenvalue; eigenvector; fPCA; high dimensions; minimax rate; optimal rate of convergence; PCA; scree plot; sparsity
Source: ORCID
Added: January 15, 2020

2014 journal article

Bayesian Models for Multiple Outcomes in Domains With Application to the Seychelles Child Development Study

Journal of the American Statistical Association, 109(505), 1–10.

By: L. Xiao, S. Thurston*, D. Ruppert*, T. Love* & P. Davidson*

author keywords: Bayesian variable selection; Latent variable model; Markov chain Monte Carlo; Methylmercury; Sparsity
Source: ORCID
Added: January 15, 2020

2014 journal article

Learning regulatory programs by threshold SVD regression

Proceedings of the National Academy of Sciences, 111(44), 15675–15680.

By: X. Ma*, L. Xiao & W. Wong*

author keywords: regulatory program; SVD; sparse; multivariate; regression
Source: ORCID
Added: January 15, 2020

2014 journal article

Quantifying the lifetime circadian rhythm of physical activity: a covariate-dependent functional approach

Biostatistics, 16(2), 352–367.

By: L. Xiao, L. Huang*, J. Schrack*, L. Ferrucci*, V. Zipunnikov* & C. Crainiceanu*

author keywords: Accelerometer; Bivariate smoothing; Covariance; Sandwich smoother; Trivariate smoothing
Source: ORCID
Added: January 15, 2020

2013 journal article

Fast bivariateP-splines: the sandwich smoother

Journal of the Royal Statistical Society: Series B (Statistical Methodology), 75(3), 577–599.

By: L. Xiao, Y. Li* & D. Ruppert*

author keywords: Asymptotics; Bivariate smoothing; Covariance function; Generalized linear array model; Non-parametric regression; Penalized splines; Sandwich smoother; Thin plate splines
Source: ORCID
Added: January 15, 2020

Employment

Updated: November 27th, 2017 22:41

2015 - present

North Carolina State University Raleigh, NC, US
Assistant Professor Department of Statistics

2012 - 2015

Johns Hopkins University Baltimore, MD, US
Postdoctoral Fellow Deparment of Biostatistics

Education

Updated: November 27th, 2017 22:38

2007 - 2012

Cornell University Ithaca, NY, US
PhD Department of Statistics