Works (38)

Updated: May 2nd, 2025 21:20

2025 article

The Evolution of CMGH as The Basic Research Journal in Gastroenterology and Hepatology: "H" is for "Home "

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, Vol. 19.

By: J. Katz*, M. Battle n & A. Vaeth*

topics (OpenAlex): Gastrointestinal Tumor Research and Treatment
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 10, 2025

2024 article

<i>CMGH:</i> Evolving to Advance Gastroenterology and Hepatology Research

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, Vol. 18, pp. 163–163.

By: M. Battle n & J. Katz*

MeSH headings : Gastroenterology / trends; Gastroenterology / methods; Humans; Biomedical Research; Periodicals as Topic
topics (OpenAlex):
Sources: Web Of Science, NC State University Libraries
Added: July 17, 2024

2023 journal article

A Balancing Act: GRHL3 Limits WNT Signaling to Promote Tissue Homeostasis in the Esophageal Epithelium

Cellular and Molecular Gastroenterology and Hepatology, 15(5), 1247–1248.

By: O. Franklin* & M. Battle*

MeSH headings : Wnt Signaling Pathway; Transcription Factors / genetics; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Epithelium / metabolism; Homeostasis
topics (OpenAlex): Cancer-related gene regulation; Helicobacter pylori-related gastroenterology studies
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2022 journal article

Pepsinogen/Proton Pump Co‐Expression in Barrett's Esophageal Cells Induces <scp>Cancer‐Associated</scp> Changes

The Laryngoscope, 133(1), 59–69.

MeSH headings : Humans; Proton Pumps; Pepsinogen A / metabolism; Proton Pump Inhibitors; Barrett Esophagus / complications; Esophageal Neoplasms / pathology; Pepsin A / metabolism; Carcinogenesis; Adenosine Triphosphatases / metabolism; Tumor Microenvironment
topics (OpenAlex): Esophageal Cancer Research and Treatment; Helicobacter pylori-related gastroenterology studies; Cancer-related gene regulation
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 27, 2024

2022 journal article

The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut

Biology Open, 11(12).

By: R. Ramadan*, V. Wouters*, S. van Neerven*, N. de Groot*, T. Garcia*, V. Muncan*, O. Franklin*, M. Battle* ...

MeSH headings : Animals; Mice; Collagen / metabolism; Extracellular Matrix; Laminin / metabolism; Laminin / pharmacology; Paneth Cells / metabolism; Stem Cells; Intestines
topics (OpenAlex): Cancer Cells and Metastasis; Digestive system and related health; Tissue Engineering and Regenerative Medicine
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2021 journal article

GATA4 Controls Epithelial Morphogenesis in the Developing Stomach to Promote Establishment of Glandular Columnar Epithelium

Cellular and Molecular Gastroenterology and Hepatology, 12(4), 1391–1413.

By: A. DeLaForest*, B. Kohlnhofer*, O. Franklin*, R. Stavniichuk*, C. Thompson*, K. Pulakanti*, S. Rao*, M. Battle*

MeSH headings : Animals; Binding Sites; Biomarkers; Esophagus; GATA4 Transcription Factor / genetics; GATA4 Transcription Factor / metabolism; GATA6 Transcription Factor / genetics; GATA6 Transcription Factor / metabolism; Gastric Mucosa / embryology; Gastric Mucosa / metabolism; Gene Expression Profiling; Gene Expression Regulation, Developmental; Immunohistochemistry; Mice; Mice, Knockout; Morphogenesis / genetics; Organogenesis / genetics; Protein Binding
topics (OpenAlex): Tracheal and airway disorders; Congenital heart defects research; Esophageal and GI Pathology
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2021 journal article

GATA4 blocks squamous epithelial cell gene expression in human esophageal squamous cells

Scientific Reports, 11(1).

By: R. Stavniichuk*, A. DeLaForest*, C. Thompson*, J. Miller*, R. Souza* & M. Battle*

MeSH headings : Adenocarcinoma / genetics; Adenocarcinoma / pathology; Barrett Esophagus / genetics; Barrett Esophagus / pathology; Cell Line; Cell Line, Tumor; Epithelial Cells / metabolism; Epithelial Cells / pathology; Esophageal Neoplasms / genetics; Esophageal Neoplasms / pathology; GATA4 Transcription Factor / genetics; Gene Amplification; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; RNA, Messenger / genetics
topics (OpenAlex): Epigenetics and DNA Methylation; Tracheal and airway disorders; Metastasis and carcinoma case studies
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2020 journal article

GATA4 Is Required for Budding Morphogenesis of Posterior Foregut Endoderm in a Model of Human Stomach Development

Frontiers in Medicine, 7.

By: A. DeLaForest*, A. Quryshi*, T. Frolkis*, O. Franklin* & M. Battle*

topics (OpenAlex): Congenital heart defects research; Digestive system and related health; Pluripotent Stem Cells Research
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2020 journal article

H+/K+ATPase Expression in the Larynx of Laryngopharyngeal Reflux and Laryngeal Cancer Patients

The Laryngoscope, 131(1), 130–135.

MeSH headings : Cells, Cultured; Gene Expression Regulation; H(+)-K(+)-Exchanging ATPase / biosynthesis; H(+)-K(+)-Exchanging ATPase / genetics; Humans; Hypopharynx / cytology; Laryngeal Neoplasms / enzymology; Laryngeal Neoplasms / genetics; Laryngopharyngeal Reflux / enzymology; Laryngopharyngeal Reflux / genetics; Larynx / enzymology; Tumor Cells, Cultured
topics (OpenAlex): Gastroesophageal reflux and treatments; Helicobacter pylori-related gastroenterology studies
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2019 journal article

The Adult Murine Intestine is Dependent on Constitutive Laminin-γ1 Synthesis

Scientific Reports, 9(1).

By: B. Fields*, A. DeLaForest*, M. Zogg*, J. May*, C. Hagen*, K. Komnick*, J. Wieser*, A. Lundberg* ...

MeSH headings : Animals; Basement Membrane / growth & development; Basement Membrane / metabolism; Embryonic Development / genetics; Female; Intestines / growth & development; Laminin / biosynthesis; Laminin / genetics; Liver / metabolism; Mice
topics (OpenAlex): Cell Adhesion Molecules Research; RNA Research and Splicing; Caveolin-1 and cellular processes
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2018 journal article

Patterning the gastrointestinal epithelium to confer regional-specific functions

Developmental Biology, 435(2), 97–108.

By: C. Thompson*, A. DeLaForest* & M. Battle*

MeSH headings : Animals; Cell Differentiation; Epithelial Cells / cytology; Epithelial Cells / physiology; Gastrointestinal Tract / cytology; Gastrointestinal Tract / embryology; Gastrointestinal Tract / physiology; Gene Expression Regulation, Developmental; Homeodomain Proteins / physiology; Humans; Intestinal Absorption; Intestinal Mucosa / cytology; Intestine, Small / cytology; Intracellular Signaling Peptides and Proteins / physiology; Mice; Morphogenesis; Multigene Family; Organ Specificity; Signal Transduction / physiology; Stomach / cytology; Transcription Factors / physiology
topics (OpenAlex): Digestive system and related health; Cancer Cells and Metastasis; Epigenetics and DNA Methylation
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2017 journal article

Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection

Stem Cell Reports, 8(3), 491–499.

By: K. Mitzelfelt*, C. McDermott-Roe*, M. Grzybowski*, M. Marquez*, C. Kuo*, M. Riedel, S. Lai*, M. Choi* ...

MeSH headings : CRISPR-Cas Systems; Cell Line; DNA End-Joining Repair; Gene Editing; Gene Knock-In Techniques; Gene Targeting; Genetic Vectors; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Induced Pluripotent Stem Cells / cytology; Induced Pluripotent Stem Cells / drug effects; Induced Pluripotent Stem Cells / metabolism; Recombinational DNA Repair
topics (OpenAlex): CRISPR and Genetic Engineering; Pluripotent Stem Cells Research; RNA regulation and disease
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2017 journal article

GATA4 Is Sufficient to Establish Jejunal Versus Ileal Identity in the Small Intestine

Cellular and Molecular Gastroenterology and Hepatology, 3(3), 422–446.

By: C. Thompson*, K. Wojta*, K. Pulakanti*, S. Rao*, P. Dawson* & M. Battle*

topics (OpenAlex): Epigenetics and DNA Methylation; Digestive system and related health; RNA modifications and cancer
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2016 journal article

A Dynamic WNT/β-CATENIN Signaling Environment Leads to WNT-Independent and WNT-Dependent Proliferation of Embryonic Intestinal Progenitor Cells

Stem Cell Reports, 7(5), 826–839.

By: A. Chin*, Y. Tsai*, S. Finkbeiner*, M. Nagy*, E. Walker*, N. Ethen*, B. Williams*, M. Battle*, J. Spence*

MeSH headings : Animals; Cell Death; Cell Differentiation; Cell Proliferation; Embryonic Stem Cells / cytology; Embryonic Stem Cells / metabolism; Gene Expression; Intestinal Mucosa / cytology; Intestinal Mucosa / metabolism; Intestines / cytology; Intestines / embryology; Low Density Lipoprotein Receptor-Related Protein-5 / genetics; Low Density Lipoprotein Receptor-Related Protein-5 / metabolism; Low Density Lipoprotein Receptor-Related Protein-6 / genetics; Low Density Lipoprotein Receptor-Related Protein-6 / metabolism; Mice; Mice, Transgenic; Morphogenesis / genetics; Myocytes, Smooth Muscle / cytology; Myocytes, Smooth Muscle / metabolism; Organogenesis / genetics; Receptor, Platelet-Derived Growth Factor alpha / metabolism; SOX9 Transcription Factor / genetics; SOX9 Transcription Factor / metabolism; Wnt Proteins / genetics; Wnt Proteins / metabolism; Wnt Signaling Pathway; beta Catenin / genetics; beta Catenin / metabolism
topics (OpenAlex): Digestive system and related health; Cancer Cells and Metastasis
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2016 journal article

GATA4 Regulates Epithelial Cell Proliferation to Control Intestinal Growth and Development in Mice

Cellular and Molecular Gastroenterology and Hepatology, 2(2), 189–209.

By: B. Kohlnhofer*, C. Thompson*, E. Walker* & M. Battle*

topics (OpenAlex): Digestive system and related health; Congenital heart defects research; Congenital Diaphragmatic Hernia Studies
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2016 journal article

Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4α (HNF4Α) Is Vital to Beta-cell Function

Journal of Biological Chemistry, 291(12), 6146–6157.

MeSH headings : Animals; Calcium / metabolism; Cell Line; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Diabetes Mellitus, Type 2 / genetics; Endoplasmic Reticulum / metabolism; Gene Expression Regulation; Glucose / physiology; HEK293 Cells; Hepatocyte Nuclear Factor 4 / physiology; Homeostasis; Humans; Insulin / metabolism; Insulin Secretion; Insulin-Secreting Cells / physiology; Mice; Regulatory Factor X Transcription Factors; Transcription Factors / genetics; Transcription Factors / metabolism; Transcription, Genetic; X-Box Binding Protein 1
topics (OpenAlex): Endoplasmic Reticulum Stress and Disease; Pancreatic function and diabetes; Adenosine and Purinergic Signaling
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2015 journal article

Increased Prefrontal Cortex Neurogranin Enhances Plasticity and Extinction Learning

The Journal of Neuroscience, 35(19), 7503–7508.

By: L. Zhong*, J. Brown*, A. Kramer*, K. Kaleka*, A. Petersen*, J. Krueger*, M. Florence*, M. Muelbl* ...

MeSH headings : Analysis of Variance; Animals; Calcium / metabolism; Calcium-Calmodulin-Dependent Protein Kinase Type 2 / genetics; Calcium-Calmodulin-Dependent Protein Kinase Type 2 / metabolism; Conditioning, Classical / physiology; Conditioning, Operant / physiology; Electric Stimulation; Extinction, Psychological / physiology; Fear / physiology; In Vitro Techniques; Long-Term Potentiation / genetics; Male; Mice; Mice, Transgenic; Neurogranin / genetics; Neurogranin / metabolism; Neuronal Plasticity / genetics; Prefrontal Cortex / cytology; Prefrontal Cortex / physiology; Pyramidal Cells / metabolism; Sucrose / administration & dosage
topics (OpenAlex): Memory and Neural Mechanisms; Neuroscience and Neuropharmacology Research; Neurogenesis and neuroplasticity mechanisms
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2014 chapter

Basic Science of Small Intestinal Development

In D. L. Gumucio, L. C. Samuelson, & J. R. Spence (Eds.), Translational Gastroenterology: Organogenesis to Disease (pp. 85–97). Hoboken, NJ: Wiley Blackwell Publishers.

By: C. Thompson & M. Battle

Ed(s): D. Gumucio, L. Samuelson & J. Spence

Source: NC State University Libraries
Added: January 20, 2025

2014 journal article

Characterization of the developing small intestine in the absence of either GATA4 or GATA6

BMC Research Notes, 7(1).

By: E. Walker*, C. Thompson*, B. Kohlnhofer*, M. Faber* & M. Battle*

MeSH headings : Animals; GATA4 Transcription Factor / metabolism; GATA6 Transcription Factor / metabolism; Intestine, Small / growth & development; Intestine, Small / metabolism; Mice; Mice, Knockout
topics (OpenAlex): Digestive system and related health; Congenital heart defects research
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2014 journal article

GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development

Developmental Biology, 392(2), 283–294.

By: E. Walker*, C. Thompson* & M. Battle*

MeSH headings : Animals; Calcium-Binding Proteins; Cell Differentiation / genetics; Cell Differentiation / physiology; Chromatin Immunoprecipitation; Fluorescent Antibody Technique; GATA4 Transcription Factor / metabolism; GATA6 Transcription Factor / metabolism; Gene Expression Regulation, Developmental / genetics; Gene Expression Regulation, Developmental / physiology; Immunohistochemistry; Intercellular Signaling Peptides and Proteins / metabolism; Intestinal Mucosa / cytology; Intestinal Mucosa / embryology; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Receptors, Notch / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction / physiology
topics (OpenAlex): Digestive system and related health; Epigenetics and DNA Methylation; Congenital heart defects research
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2014 chapter

Translational Gastroenterology

In D. L. Gumucio, L. C. Samuelson, & J. R. Spence (Eds.), Basic Science of Small Intestinal Development (pp. 85–97). Hoboken, NJ: Wiley Blackwell Publishers.

By: C. Thompson & M. Battle

Ed(s): D. Gumucio, L. Samuelson & J. Spence

Source: NC State University Libraries
Added: January 20, 2025

2012 journal article

E-cadherin is required for intestinal morphogenesis in the mouse

Developmental Biology, 371(1), 1–12.

By: B. Bondow*, M. Faber*, K. Wojta*, E. Walker* & M. Battle*

MeSH headings : Animals; Cadherins / genetics; Cadherins / metabolism; Cell Adhesion / physiology; Fluorescent Antibody Technique; Homeostasis / physiology; Immunoblotting; Immunohistochemistry; Intestinal Mucosa / embryology; Intestinal Mucosa / ultrastructure; Intestine, Small / cytology; Intestine, Small / embryology; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Morphogenesis / physiology; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; beta Catenin / metabolism
topics (OpenAlex): Cancer-related gene regulation; Barrier Structure and Function Studies
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2012 journal article

Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

Journal of Hepatology, 57(5), 1061–1068.

By: J. Patankar*, S. Obrowsky*, P. Doddapattar*, G. Hoefler*, M. Battle*, S. Levak-Frank*, D. Kratky*

MeSH headings : AMP-Activated Protein Kinase Kinases; Animals; Choline Deficiency; Diet / adverse effects; Disease Models, Animal; Fatty Acids, Nonesterified / metabolism; Fatty Liver / chemically induced; Fatty Liver / metabolism; Fatty Liver / prevention & control; GATA4 Transcription Factor / deficiency; GATA4 Transcription Factor / genetics; GATA4 Transcription Factor / metabolism; Glucagon-Like Peptide 1 / metabolism; Jejunum / metabolism; Lipid Metabolism / physiology; Liver Cirrhosis / chemically induced; Liver Cirrhosis / metabolism; Liver Cirrhosis / prevention & control; Male; Methionine / deficiency; Mice; Mice, Knockout; Protein Kinases / metabolism; Sterol Regulatory Element Binding Protein 1 / metabolism; Thiobarbituric Acid Reactive Substances / metabolism; Triglycerides / metabolism
topics (OpenAlex): Diet and metabolism studies; Pancreatic function and diabetes; Liver Disease Diagnosis and Treatment
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2012 journal article

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

Journal of Clinical Investigation, 122(10), 3516–3528.

By: S. Xuan*, M. Borok*, K. Decker*, M. Battle*, S. Duncan*, M. Hale*, R. Macdonald, L. Sussel*

MeSH headings : Animals; Basic Helix-Loop-Helix Transcription Factors / analysis; Binding Sites; Carboxypeptidases A / analysis; Cell Differentiation; Cell Division; Cell Lineage; Disease Models, Animal; Endoderm / metabolism; Epithelial Cells / pathology; GATA4 Transcription Factor / deficiency; GATA4 Transcription Factor / genetics; GATA4 Transcription Factor / physiology; GATA6 Transcription Factor / deficiency; GATA6 Transcription Factor / genetics; GATA6 Transcription Factor / physiology; Gene Expression Regulation, Developmental / genetics; Gene Knockdown Techniques; Genotype; Gestational Age; Hyperglycemia / congenital; Hyperglycemia / genetics; Insulin / metabolism; Insulin Secretion; Mice; Nerve Tissue Proteins / analysis; Organ Specificity; Organogenesis / genetics; Pancreas / abnormalities; Pancreas / embryology; Pancreas / pathology; Transcription, Genetic
topics (OpenAlex): Pancreatic function and diabetes; Congenital heart defects research
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2011 journal article

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

Nature Medicine, 17(12), 1585–1593.

By: N. Shulzhenko*, A. Morgun*, W. Hsiao*, M. Battle*, M. Yao*, O. Gavrilova*, M. Orandle*, L. Mayer* ...

MeSH headings : Animals; B-Lymphocytes / immunology; B-Lymphocytes / metabolism; DNA, Bacterial / isolation & purification; Epithelial Cells / immunology; Epithelial Cells / microbiology; GATA4 Transcription Factor / genetics; GATA4 Transcription Factor / metabolism; Gene Expression Profiling; Gene Regulatory Networks; Humans; Immunoglobulin A / immunology; Intestinal Mucosa / immunology; Intestinal Mucosa / metabolism; Intestinal Mucosa / microbiology; Lipid Metabolism; Metagenome; Mice; Mice, Inbred BALB C; Mice, Knockout; Microarray Analysis; Up-Regulation
topics (OpenAlex): Diabetes and associated disorders; Gut microbiota and health; Immune Cell Function and Interaction
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2011 journal article

HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells

Development, 138(19), 4143–4153.

By: A. DeLaForest*, M. Nagaoka*, K. Si-Tayeb*, F. Noto*, G. Konopka*, M. Battle*, S. Duncan*

MeSH headings : Animals; Cell Differentiation; Cell Lineage; Cell Proliferation; Gene Expression Regulation, Developmental; Hepatocyte Nuclear Factor 4 / metabolism; Hepatocyte Nuclear Factor 4 / physiology; Hepatocytes / cytology; Humans; Lentivirus / genetics; Liver / embryology; Mice; Pluripotent Stem Cells / cytology; RNA, Small Interfering / metabolism
topics (OpenAlex): Pluripotent Stem Cells Research; Liver physiology and pathology; Pancreatic function and diabetes
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2011 journal article

Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice

American Journal of Physiology-Endocrinology and Metabolism, 300(3), E478–E488.

By: J. Patankar*, P. Chandak*, S. Obrowsky*, T. Pfeifer*, C. Diwoky, A. Uellen*, W. Sattler*, R. Stollberger ...

MeSH headings : Adipose Tissue / anatomy & histology; Animals; Diet; Dietary Fats / pharmacokinetics; Enzyme-Linked Immunosorbent Assay; Feces / chemistry; GATA4 Transcription Factor / genetics; GATA4 Transcription Factor / physiology; Gastric Emptying / physiology; Glucagon-Like Peptide 1 / physiology; Glucose Tolerance Test; Hyperlipidemias / genetics; Hyperlipidemias / metabolism; Insulin Resistance / genetics; Insulin Resistance / physiology; Intestinal Absorption / genetics; Intestinal Absorption / physiology; Intestinal Mucosa / metabolism; Lipolysis / physiology; Magnetic Resonance Imaging; Mice; Mice, Knockout; Obesity / genetics; Obesity / metabolism; RNA / biosynthesis; RNA / genetics; Reverse Transcriptase Polymerase Chain Reaction; Tissue Distribution
topics (OpenAlex): Congenital heart defects research; Pancreatic function and diabetes; Genomic variations and chromosomal abnormalities
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2010 journal article

Highly Efficient Generation of Human Hepatocyte–Like Cells From Induced Pluripotent Stem Cells

Hepatology, 51(1), 297–305.

By: K. Si-Tayeb*, F. Noto*, M. Nagaoka*, J. Li*, M. Battle*, C. Duris*, P. North*, S. Dalton*, S. Duncan*

MeSH headings : Animals; Cell Differentiation / physiology; Hepatocytes / transplantation; Humans; Induced Pluripotent Stem Cells / physiology; Mice
topics (OpenAlex): Pluripotent Stem Cells Research; CRISPR and Genetic Engineering; Pancreatic function and diabetes
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2010 journal article

The Peroxisomal<i>3-keto-acyl-CoA thiolase B</i>Gene Expression Is under the Dual Control of PPARα and HNF4α in the Liver

PPAR Research, 2010, 1–17.

By: J. Chamouton*, F. Hansmannel*, J. Bonzo*, M. Clémencet*, G. Chevillard*, M. Battle*, P. Martin, T. Pineau ...

topics (OpenAlex): Peroxisome Proliferator-Activated Receptors; Adipose Tissue and Metabolism; Metabolism, Diabetes, and Cancer
Sources: Crossref, NC State University Libraries
Added: December 27, 2024

2009 journal article

Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice #

Hepatology, 49(5), 1645–1654.

By: K. Sun, M. Battle*, R. Misra* & S. Duncan

MeSH headings : Animals; Blood Glucose / analysis; Body Size; Cell Proliferation; Cell Survival; Female; Gene Expression; Hepatocytes / metabolism; Insulin-Like Growth Factor I / metabolism; Liver / physiology; Male; Mice; Mice, Knockout; Organ Size; Organogenesis; Serum Response Factor / metabolism; Triglycerides / blood
topics (OpenAlex): Growth Hormone and Insulin-like Growth Factors; Liver physiology and pathology; Pancreatic function and diabetes
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2008 journal article

GATA4 Is Essential for Jejunal Function in Mice

Gastroenterology, 135(5), 1676–1686.e1.

By: M. Battle*, B. Bondow*, M. Iverson*, S. Adams*, R. Jandacek*, P. Tso*, S. Duncan*

MeSH headings : Animals; Cholesterol, Dietary / pharmacokinetics; DNA / genetics; Dietary Fats / pharmacokinetics; Enterocytes / cytology; Enterocytes / metabolism; GATA4 Transcription Factor / biosynthesis; GATA4 Transcription Factor / genetics; Gene Expression; Ileum / cytology; Ileum / physiology; Immunohistochemistry; Intestinal Absorption / physiology; Jejunum / cytology; Jejunum / physiology; Mice; Reverse Transcriptase Polymerase Chain Reaction; Zinc Fingers
topics (OpenAlex): Pediatric Hepatobiliary Diseases and Treatments; Epigenetics and DNA Methylation; Drug Transport and Resistance Mechanisms
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2008 journal article

Hepatocyte nuclear factor 4α is implicated in endoplasmic reticulum stress–induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H†

Hepatology, 48(4), 1242–1250.

By: J. Luebke‐Wheeler*, K. Zhang*, M. Battle*, K. Si‐Tayeb*, W. Garrison*, S. Chhinder*, J. Li*, R. Kaufman*, S. Duncan*

MeSH headings : Acute-Phase Proteins / drug effects; Acute-Phase Proteins / metabolism; Animals; Anti-Bacterial Agents / pharmacology; Cell Differentiation; Cyclic AMP Response Element-Binding Protein / genetics; Cyclic AMP Response Element-Binding Protein / metabolism; Endoplasmic Reticulum / metabolism; Gastric Mucosa / metabolism; Hepatocyte Nuclear Factor 4 / genetics; Hepatocyte Nuclear Factor 4 / metabolism; Hepatocytes / cytology; Hepatocytes / drug effects; Hepatocytes / metabolism; Intestine, Small / metabolism; Liver / cytology; Liver / embryology; Liver / metabolism; Mice; Mice, Inbred Strains; Mice, Knockout; RNA, Messenger / metabolism; Tunicamycin / pharmacology
topics (OpenAlex): Pancreatic function and diabetes; Endoplasmic Reticulum Stress and Disease; Genetics and Neurodevelopmental Disorders
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 27, 2024

2008 journal article

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice

Developmental Biology, 317(2), 614–619.

By: R. Zhao*, A. Watt*, M. Battle*, J. Li*, B. Bondow* & S. Duncan*

MeSH headings : Animals; Cell Differentiation / physiology; Endoderm / physiology; GATA4 Transcription Factor / deficiency; GATA4 Transcription Factor / metabolism; GATA6 Transcription Factor / deficiency; GATA6 Transcription Factor / metabolism; Gene Expression Regulation, Developmental / genetics; Heart / embryology; Immunohistochemistry; In Situ Hybridization; Mice; Mice, Knockout; Models, Biological; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Oligonucleotides; Reverse Transcriptase Polymerase Chain Reaction
topics (OpenAlex): Congenital heart defects research; Pluripotent Stem Cells Research; Chromosomal and Genetic Variations
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2006 journal article

Hepatocyte Nuclear Factor 4α Is Essential for Embryonic Development of the Mouse Colon

Gastroenterology, 130(4), 19.e1–19.e.

By: W. Garrison*, M. Battle*, C. Yang*, K. Kaestner*, F. Sladek* & S. Duncan*

MeSH headings : Animals; Cell Count; Colon / embryology; Embryo, Mammalian / cytology; Embryo, Mammalian / metabolism; Embryonic Development / physiology; Gastric Mucosa / embryology; Gene Expression / physiology; Goblet Cells / physiology; Hepatocyte Nuclear Factor 4 / genetics; Hepatocyte Nuclear Factor 4 / physiology; Immunohistochemistry; Intestinal Mucosa / embryology; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Reference Values; Reverse Transcriptase Polymerase Chain Reaction
topics (OpenAlex): Pancreatic function and diabetes; Digestive system and related health; FOXO transcription factor regulation
Sources: Crossref, NC State University Libraries
Added: December 27, 2024

2006 journal article

Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

Proceedings of the National Academy of Sciences, 103(22), 8419–8424.

By: M. Battle*, G. Konopka*, F. Parviz*, A. Gaggl*, C. Yang*, F. Sladek*, S. Duncan*

MeSH headings : Animals; Cadherins / metabolism; Cell Adhesion Molecules / genetics; Cell Adhesion Molecules / metabolism; Cell Differentiation; Epithelial Cells / cytology; Epithelial Cells / metabolism; Female; Gene Expression Regulation, Developmental; Hepatocyte Nuclear Factor 4 / deficiency; Hepatocyte Nuclear Factor 4 / genetics; Hepatocyte Nuclear Factor 4 / metabolism; Intercellular Junctions / metabolism; Liver / cytology; Liver / embryology; Liver / metabolism; Male; Mice; Mice, Transgenic; Microscopy, Electron, Transmission
topics (OpenAlex): Liver physiology and pathology; Pancreatic function and diabetes
Sources: Crossref, NC State University Libraries
Added: December 27, 2024

2006 journal article

Transcriptional regulation of the human hepatic lipase (LIPC) gene promoter

Journal of Lipid Research, 47(7), 1463–1477.

By: L. Rufibach*, S. Duncan*, M. Battle* & S. Deeb*

MeSH headings : Animals; Base Sequence; Binding Sites / genetics; COS Cells; COUP Transcription Factor II / genetics; COUP Transcription Factor II / metabolism; Cell Line; Chlorocebus aethiops; DNA / genetics; DNA / metabolism; Gene Expression Regulation, Enzymologic; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Hepatocyte Nuclear Factor 1-alpha / genetics; Hepatocyte Nuclear Factor 1-alpha / metabolism; Hepatocyte Nuclear Factor 4 / antagonists & inhibitors; Hepatocyte Nuclear Factor 4 / deficiency; Hepatocyte Nuclear Factor 4 / genetics; Hepatocyte Nuclear Factor 4 / metabolism; Humans; Lipase / genetics; Lipase / metabolism; Liver / enzymology; Mice; Mice, Knockout; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear / metabolism; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism; Transcriptional Activation; Transfection
topics (OpenAlex): Diabetes and associated disorders; Pancreatic function and diabetes; Lipid metabolism and disorders
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2004 journal article

GATA4 is essential for formation of the proepicardium and regulates cardiogenesis

Proceedings of the National Academy of Sciences, 101(34), 12573–12578.

By: A. Watt*, M. Battle*, J. Li* & S. Duncan*

MeSH headings : Animals; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Embryo, Mammalian / anatomy & histology; Embryo, Mammalian / physiology; Embryonic Structures / anatomy & histology; Embryonic Structures / physiology; GATA4 Transcription Factor; Genetic Complementation Test; Heart / anatomy & histology; Heart / embryology; Heart Defects, Congenital; Mice; Mice, Knockout; Morphogenesis / physiology; Myocardium / cytology; Myocardium / metabolism; Myocardium / pathology; Pericardium / anatomy & histology; Pericardium / embryology; Stem Cells / physiology; Transcription Factors / genetics; Transcription Factors / metabolism
topics (OpenAlex): Congenital heart defects research; RNA modifications and cancer; Congenital Heart Disease Studies
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

2003 journal article

ST7 Is a Novel Low-Density Lipoprotein Receptor-Related Protein (LRP) with a Cytoplasmic Tail that Interacts with Proteins Related to Signal Transduction Pathways

Biochemistry, 42(24), 7270–7282.

By: M. Battle*, V. Maher* & J. McCormick*

MeSH headings : Amino Acid Motifs; Amino Acid Sequence; Base Sequence; Carrier Proteins / metabolism; Cytoplasm / metabolism; Endocytosis / physiology; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins / chemistry; Membrane Proteins / genetics; Membrane Proteins / metabolism; Molecular Sequence Data; Myogenic Regulatory Factors / metabolism; Peptides / metabolism; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Tertiary; Receptors for Activated C Kinase; Receptors, LDL / chemistry; Receptors, LDL / genetics; Receptors, LDL / metabolism; Sequence Alignment; Sequence Homology, Amino Acid; Serine Endopeptidases; Signal Transduction / physiology; Tumor Cells, Cultured
topics (OpenAlex): Protease and Inhibitor Mechanisms; Cellular transport and secretion; Cell Adhesion Molecules Research
Sources: Crossref, NC State University Libraries
Added: December 20, 2024

Employment

Updated: February 7th, 2024 15:32

2023 - present

North Carolina State University Raleigh, US
Professor and Department Head Molecular Biomedical Sciences

2003 - 2023

Medical College of Wisconsin Milwaukee, Wisconsin, US
Professor Cell Biology, Neurobiology, and Anatomy

Funding History

Funding history based on the linked ORCID record. Updated: February 21st, 2023 18:01

grant August 1, 2022 - May 31, 2026
Defining GATA4’s Molecular Function in Gastric Cell Biology
National Institute of Diabetes and Digestive and Kidney Diseases
grant June 1, 2020 - May 31, 2021
RAPID: How do vertebrate endolysosomal Ca2+ channels control coronaviral tropism?
Directorate for Biological Sciences
grant July 1, 2017 - June 30, 2022
GATA4 in development of a normal squamocolumnar junction and Barretts esophagus
National Institute of Diabetes and Digestive and Kidney Diseases
grant May 15, 2017 - November 14, 2018
Epithelial and Neuronal Interactions in Colitis: A Role for Sensory Neurons in Protecting the Colon Epithelium
Congressionally Directed Medical Research Programs
grant September 15, 2016 - August 31, 2017
Determining the mechanisms regulating functional regionalization of the intestine
National Institute of Diabetes and Digestive and Kidney Diseases
grant July 1, 2010 - June 30, 2016
Determining the Mechanisms Regulating Functional Regionalization of the Intestine
National Institute of Diabetes and Digestive and Kidney Diseases
grant June 1, 2004 - May 31, 2007
The role of HNF4 in gastrointestinal development
National Institute of Diabetes and Digestive and Kidney Diseases

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