Trudy F. MacKay

Natural genetic variation in a dopamine receptor is associated with variation in female fertility in Drosophila melanogaster

Epistasis for head morphology in Drosophila melanogaster

G3-GENES GENOMES GENETICS, 11(10).

Functional Diversification, Redundancy, and Epistasis among Paralogs of the Drosophila melanogaster Obp50a-d Gene Cluster

MOLECULAR BIOLOGY AND EVOLUTION, 38(5), 2030–2044.

Genetic basis of variation in cocaine and methamphetamine consumption in outbred populations of Drosophila melanogaster

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(23).

Heat shock proteins and small nucleolar RNAs are dysregulated in a Drosophila model for feline hypertrophic cardiomyopathy

G3-GENES GENOMES GENETICS, 11(1).

Context-dependent genetic architecture of Drosophila life span

PLOS BIOLOGY, 18(3).

Gene expression networks in the Drosophila Genetic Reference Panel

GENOME RESEARCH, 30(3), 485–496.

Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster

G3-GENES GENOMES GENETICS, 10(3), 1087–1098.

Genetic Basis of Natural Variation in Spontaneous Grooming in Drosophila melanogaster

G3-GENES GENOMES GENETICS, 10(9), 3453–3460.

Genotype by environment interaction for gene expression in Drosophila melanogaster

NATURE COMMUNICATIONS, 11(1).

Leveraging Multiple Layers of Data To Predict Drosophila Complex Traits

G3-GENES GENOMES GENETICS, 10(12), 4599–4613.

Rapid and Predictable Evolution of Admixed Populations Between Two Drosophila Species Pairs

GENETICS, 214(1), 211–230.

Systems genetics of the Drosophila metabolome

GENOME RESEARCH, 30(3), 392–405.

Genetics of cocaine and methamphetamine consumption and preference in Drosophila melanogaster

PLOS GENETICS, 15(5).

Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster

BEHAVIOR GENETICS, 49(1), 60–82.

Lisinopril Preserves Physical Resilience and Extends Life Span in a Genotype-Specific Manner in Drosophila melanogaster

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 74(12), 1844–1852.

Effect of genetic architecture on the prediction accuracy of quantitative traits in samples of unrelated individuals

HEREDITY, 120(6), 500–514.

Estimating Realized Heritability in Panmictic Populations

GENETICS, 208(1), 89–95.

Evaluation of genes associated with human myxomatous mitral valve disease in dogs with familial myxomatous mitral valve degeneration

VETERINARY JOURNAL, 232, 16–19.

Relationship Between Sequence Homology, Genome Architecture, and Meiotic Behavior of the Sex Chromosomes in North American Voles

GENETICS, 210(1), 83–97.

Artificial selection on chill-coma recovery time in Drosophila melanogaster: Direct and correlated responses to selection

JOURNAL OF THERMAL BIOLOGY, 59, 77–85.

Natural variability in Drosophila larval and pupal NaCl tolerance

JOURNAL OF INSECT PHYSIOLOGY, 88, 15–23.

Genetic Architecture of Micro-Environmental Plasticity in Drosophila melanogaster

SCIENTIFIC REPORTS, 5.

Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines

Genome Research, 24(7), 1193–1208.

Alcohol Sensitivity in Drosophila: Translational Potential of Systems Genetics

GENETICS, 183(2), 733–745.

Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep

NATURE GENETICS, 41(3), 371–375.

Quantitative Trait Loci for Aggressive Behavior in Drosophila melanogaster

GENETICS, 182(3), 889–897.

Systems genetics of complex traits in Drosophila melanogaster

NATURE GENETICS, 41(3), 299–307.

Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(34), 12393–12398.

Phenotypic plasticity and genotype by environment interaction for olfactory behavior in Drosophila melanogaster

GENETICS, 179(2), 1079–1088.

Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure

GENETICS, 179(3), 1327–1336.

Ain't misbehavin? Genotype-environment interactions and the genetics of behavior

TRENDS IN GENETICS, 23(7), 311–314.

Association of polymorphisms in odorant-binding protein genes with variation in olfactory response to benzaldehyde in Drosophila

GENETICS, 177(3), 1655–1665.

Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping

MECHANISMS OF AGEING AND DEVELOPMENT, 128(3), 237–249.

Genetic and behavioral analysis of natural variation in Drosophila melanogaster pupation position

FLY, 1(1), 23–32.

Speed-mapping quantitative trait loci using microarrays

NATURE METHODS, 4(10), 839–841.

The early developmental gene Semaphorin 5c contributes to olfactory behavior in adult Drosophila

GENETICS, 176(2), 947–956.

Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster

GENETICS, 174(3), 1349–1363.

High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster

GENETICS, 173(3), 1455–1463.

Phenotypic variation and natural selection at Catsup, a pleiotropic quantitative trait gene in Drosphila

CURRENT BIOLOGY, 16(9), 912–919.

Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster

NATURE GENETICS, 38(7), 824–829.

Quantitative genomics of aggressive behavior in Drosophila melanogaster

PLOS GENETICS, 2(9), 1386–1395.

Quantitative trait loci for locomotor behavior in Drosophila melanogaster

GENETICS, 174(1), 271–284.

Quantitative trait loci for thermotolerance phenotypes in Drosophila melanogaster

HEREDITY, 96(3), 232–242.

Quantitative trait loci with age-specific effects on fecundity in Drosophila melanogaster

[Review of ]. GENETICS, 172(3), 1595–1605.

The genetic basis of postzygotic reproductive isolation between Drosophila santomea and D-yakuba due to hybrid male sterility

GENETICS, 173(1), 225–233.

The genetic basis of prezygotic reproductive isolation between Drosophila santomea and D-yakuba due to mating preference

GENETICS, 173(1), 215–223.

Drosophila bristles and the nature of quantitative genetic variation

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 360(1459), 1513–1527.

Genetics and genomics of Drosophila mating behavior

Mackay, T. F. C., Heinsohn, S. L., Lyman, R. F., Moehring, A. J., Morgan, T. J., & Rollmann, S. M. (2005, May 3). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 102, pp. 6622–6629.

Microclinal variation for ovariole number and body size in Drosophila melanogaster in 'Evolution Canyon'

GENETICA, 123(3), 263–270.

Pinocchio, a novel protein expressed in the antenna, contributes to olfactory behavior in Drosophila melanogaster

JOURNAL OF NEUROBIOLOGY, 63(2), 146–158.

Polygenic mutation in Drosophila melanogaster: Mapping spontaneous mutations affecting sensory bristle number

GENETICS, 170(4), 1723–1735.

Positive assortative mating with family size as a function of predicted parental breeding values

GENETICS, 171(3), 1311–1320.

Quantitative trait loci affecting the difference in pigmentation between Drosophila yakuba and D. santomea

GENETICS, 171(1), 211–225.

Accumulation of transposable elements in the genome of Drosophila melanogaster is associated with a decrease in fitness

JOURNAL OF HEREDITY, 95(4), 284–290.

Complementing complexity

Mackay, T. F. C. (2004, November). NATURE GENETICS, Vol. 36, pp. 1145–1147.

Douglas Scott Falconer (1913-2004)

Mackay, T. F. C. (2004, August). HEREDITY, Vol. 93, pp. 119–121.

No evidence for an association between common nonsynonymous polymorphisms in Delta and bristle number variation in natural and laboratory populations of Drosophila melanogaster

GENETICS, 166(1), 291–306.

Quantitative genetic analyses of complex behaviours in Drosophila

[Review of ]. NATURE REVIEWS GENETICS, 5(11), 838–849.

Quantitative trait loci affecting natural variation in Drosophila longevity

MECHANISMS OF AGEING AND DEVELOPMENT, 125(3), 179–189.

Quantitative trait loci affecting starvation resistance in Drosophila melanogaster

GENETICS, 166(4), 1807–1823.

Quantitative trait loci for sexual isolation between Drosophila simulans and D-mauritiana

GENETICS, 167(3), 1265–1274.

Shuttle craft: a candidate quantitative trait gene for Drosophila lifespan

AGING CELL, 3(5), 297–307.

The genetic architecture of quantitative traits: lessons from Drosophila

[Review of ]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 14(3), 253–257.

The quantitative genetic basis of male mating behavior in Drosophila melanogaster

GENETICS, 167(3), 1249–1263.

Dopa decarboxylase (Ddc) affects variation in Drosophila longevity

NATURE GENETICS, 34(4), 429–433.

Genotype-environment interactions at quantitative trait loci affecting inflorescence development in Arabidopsis thaliana

Genetics, 165(1), 353–365.

Heterogeneous selection at specific loci in natural environments in Arabidopsis thaliana

Genetics, 165(1), 321–329.

Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development

CURRENT BIOLOGY, 13(16), 1388–1397.

Scribble is essential for olfactory Behavior in Drosphila melanogaster

Genetics, 164(4), 1447–1457.

The genetic architecture of odor-guided behavior in Drosophila: epistasis and the transcriptome

NATURE GENETICS, 35(2), 180–184.

Transcription profiling in Drosophila eyes that overexpress the human glaucoma-associated trabecular meshwork-inducible glucocorticoid response protein/myocilin (TIGR/MYOC)

Genetics, 163(2), 637–645.

Association of single-nucleotide polymorphisms at the Delta locus with genotype by environment interaction for sensory bristle number in Drosophila melanogaster

GENETICS RESEARCH, 79(3), 211–218.

Enabling population and quantitative genomics

[Review of ]. GENETICS RESEARCH, 80(1), 1–6.

Novel loci control variation in reproductive timing in Arabidopsis thaliana in natural environments

Genetics, 162(4), 1875–1884.

Quantitative trait loci for inflorescence development in Arabidopsis thaliana

Genetics, 160(3), 1133–1151.

The DSC1 channel, encoded by the smi60E locus, contributes to odor-guided behavior in Drosophila melanogaster

Genetics, 161(4), 1507–1516.

The complex genetic architecture of Drosophila life span

EXPERIMENTAL AGING RESEARCH, 28(4), 361–390.

The genetic architecture of drosophila sensory bristle number

Genetics, 162(4), 1655–1674.

The hairy: A quantitative trait locus for Drosophila sensory bristle number

Genetics, 162(1), 155–164.

The nature of quantitative genetic variation for Drosophila longevity

Mechanisms of Ageing and Development, 123(2-3), 95–104.

Vanaso is a candidate quantitative trait gene for Drosophila olfactory behavior

Genetics, 162(3), 1321–1328.

Variation in Drosophila sensory bristle number at 'Evolution Canyon'

GENETICS RESEARCH, 80(3), 215–223.

Functional genomics of odor-guided behavior in Drosophila melanogaster

CHEMICAL SENSES, 26(2), 215–221.

Quantitative trait loci in Drosophila

[Review of ]. NATURE REVIEWS GENETICS, 2(1), 11–20.

Quantitative trait locus mapping of fitness-related traits in Drosophila melanogaster

GENETICAL RESEARCH, 77(1), 107–116.

The genetic architecture of odor-guided behavior in Drosophila melanogaster

BEHAVIOR GENETICS, 31(1), 17–27.

The genetic architecture of quantitative traits

[Review of ]. ANNUAL REVIEW OF GENETICS, 35, 303–339.

Both naturally occurring insertions of transposable elements and intermediate frequency polymorphisms at the achaete-scute complex are associated with variation in bristle number in Drosophila melanogaster

Genetics, 154(3), 1255–1269.

Deficiency mapping of quantitative trait loci affecting longevity in Drosophila melanogaster

Genetics, 156(3), 1129–1146.

Genotype-environment interaction for quantitative trait loci affecting life span in Drosophila melanogaster

Genetics, 154(1), 213–227.

Quantitative trait loci for floral morphology in Arabidopsis thaliana

Genetics, 156(3), 1379–1392.

Quantitative trait loci for life span in Drosophila melanogaster: Interactions with genetic background and larval density

Genetics, 155(4), 1773–1788.

High-resolution mapping of quantitative trait loci for sternopleural bristle number in Drosophila melanogaster

Genetics, 152(4), 1585–1604.

Linkage disequilibrium mapping of molecular polymorphisms at the scabrous locus associated with naturally occurring variation in bristle number in Drosophila melanogaster

GENETICS RESEARCH, 74(3), 303–311.

The genetic architecture of selection response: Inferences from fine-scale mapping of bristle number quantitative trait loci in Drosophila melanogaster

Genetics, 153(3), 1317–1331.

Candidate quantitative trait loci and naturally occurring phenotypic variation for bristle number in Drosophila melanogaster: The Delta-Hairless gene region

Genetics, 149(2), 983–998.

Epistatic interactions between smell-impaired loci in Drosophila melanogaster

Genetics, 148(4), 1885–1891.

Genotype-environment interaction at quantitative trait loci affecting sensory bristle number in Drosophila melanogaster

Genetics, 149(4), 1883–1898.

Heterosis for viability, fecundity, and male fertility in Drosophila melanogaster: Comparison of mutational and standing variation

Genetics, 148(3), 1171–1188.

Pervasive effects of P element mutagenesis on body size in Drosophila melanogaster

GENETICS RESEARCH, 72(1), 19–24.

Quantitative genetics of ovariole number in Drosophila melanogaster. II. Mutational variation and genotype-environment interaction

Genetics, 148(1), 201–210.

Quemao, a Drosophila bristle locus, encodes geranylgeranyl pyrophosphate synthase

Genetics, 149(2), 1051–1061.

The mutation rates of di-, tri- and tetranucleotide repeats in Drosophila melanogaster

MOLECULAR BIOLOGY AND EVOLUTION, 15(12), 1751–1760.

Two sites in the Delta gene region contribute to naturally occurring variation in bristle number in Drosophila melanogaster

Genetics, 149(2), 999–1017.

Accumulation of transposable elements in laboratory lines of Drosophila melanogaster

GENETICA, Vol. 100, pp. 167–175.

Genetic and molecular analysis of smooth, a quantitative trait locus affecting bristle number in Drosophila melanogaster

Genetics, 146(2), 607–618.

Low mutation rates of microsatellite loci in Drosophila melanogaster

NATURE GENETICS, 15(1), 99–102.

Quantitative genetics of ovariole number in Drosophila melanogaster. I. Segregating variation and fitness

Evolution, 51(4), 1156–1163.

Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 94(18), 9734–9739.

The contribution of new mutations to genotype-environment interaction for fitness in Drosophila melanogaster

Evolution, 50(6), 2316–2327.

The nature of quantitative genetic variation revisited: Lessons from Drosophila bristles

[Review of ]. BIOESSAYS, 18(2), 113–121.

THE GENETIC-BASIS OF QUANTITATIVE VARIATION - NUMBERS OF SENSORY BRISTLES OF DROSOPHILA-MELANOGASTER AS A MODEL SYSTEM

TRENDS IN GENETICS, 11(12), 464–470.

A drosophila model for toxicogenomics: Genetic variation in susceptibility to heavy metal exposure

Zhou, S. S., Luoma, S. E., Armour, G. E. S., Thakkar, E., Mackay, T. F. C., & Anholt, R. R. H. PLoS Genetics, 13(7).

A transcriptional network associated with natural variation in Drosophila aggressive behavior

Edwards, A. C., Ayroles, J. F., Stone, E. A., Carbone, M. A., Lyman, R. F., & Mackay, T. F. C. Genome Biology, 10(7).

A-maize-ing diversity

Mackay, T. F. C. Science, 325(5941), 688–689.

Accounting for genetic architecture improves sequence based genomic prediction for a Drosophila fitness trait

Ober, U., Huang, W., Magwire, M., Schlather, M., Simianer, H., & Mackay, T. F. C. PLoS One, 10(5).

Alan Robertson (1920-1989)

Mackay, T. F. C. Genetics, 125(1), 1.

Analysis of natural variation reveals neurogenetic networks for Drosophila olfactory behavior

Swarup, S., Huang, W., Mackay, T. F. C., & Anholt, R. R. H. Proceedings of the National Academy of Sciences of the United States of America, 110(3), 1017–1022.

Anecdotal, historical and critical commentaries on genetics

Hill, W. G., & Mackay, T. F. C. Genetics, 167(4), 1529–1536.

Charting the genotype-phenotype map: Lessons from the Drosophila melanogaster genetic reference panel

Mackay, T. F. C., & Huang, W. [Review of ]. Wiley Interdisciplinary Reviews-Developmental Biology, 7(1).

Complex genetic architecture of Drosophila aggressive behavior

Zwarts, L., Magwire, M. M., Carbone, M. A., Versteven, M., Herteleer, L., Anholt, R. R. H., … Mackay, T. F. C. Proceedings of the National Academy of Sciences of the United States of America, 108(41), 17070–17075.