Michael Cowley

Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction

Simmers, M. D., Hudson, K. M., Baptissart, M., & Cowley, M. (2022, July 1). EPIGENETICS, Vol. 7.

Genomic map of candidate human imprint control regions: the imprintome

Jima, D. D., Skaar, D. A., Planchart, A., Motsinger-Reif, A., Cevik, S. E., Park, S. S., … Hoyo, C. (2022, June 25). EPIGENETICS, Vol. 6.

The imprinted gene Zac1 regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease

Riegl, S. D., Starnes, C., Jima, D. D., Baptissart, M., Diehl, A. M., Belcher, S. M., & Cowley, M. (2022, October 6). TOXICOLOGICAL SCIENCES, Vol. 10.

Zac1 and the Imprinted Gene Network program juvenile NAFLD in response to maternal metabolic syndrome

Baptissart, M., Bradish, C. M., Jones, B. S., Walsh, E., Tehrani, J., Marrero-Colon, V., … Cowley, M. (2022, February 28). HEPATOLOGY, Vol. 2.

Imprinted Gene Expression and Function of the Dopa Decarboxylase Gene in the Developing Heart

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 9.

Transcriptomic, proteomic, and metabolomic analyses identify candidate pathways linking maternal cadmium exposure to altered neurodevelopment and behavior

SCIENTIFIC REPORTS, 11(1).

Transcription of intragenic CpG islands influences spatiotemporal host gene pre-mRNA processing

NUCLEIC ACIDS RESEARCH, 48(15), 8349–8359.

Maternal cadmium exposure in the mouse leads to increased heart weight at birth and programs susceptibility to hypertension in adulthood

SCIENTIFIC REPORTS, 9(1).

Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study

EPIGENETICS, 14(4), 325–340.

Effects of Cadmium Exposure on DNA Methylation at Imprinting Control Regions and Genome-Wide in Mothers and Newborn Children.

Environmental Health Perspectives, 3(3).

Neonatal mice exposed to a high-fat diet in utero influence the behaviour of their nursing dam

Proceedings of the Royal Society B: Biological Sciences, 285(1891), 20181237.

Regulatory links between imprinted genes: Evolutionary predictions and consequences

Regulatory links between imprinted genes: evolutionary predictions and consequences.

Coadaptation between Mother and Offspring: Why Not?

Wolf, J. B., Cowley, M., & Ward, A. (2015, March). PLOS BIOLOGY, Vol. 13.

Antagonistic roles in fetal development and adult physiology for the oppositely imprinted Grb10 and Dlk1 genes.

BMC Biology, 12, 771,

Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pup.

PLoS Biology, 12(2), 1001799,

Transposable elements re-wire and fine-tune the transcriptome.

9(1), 1003234.

Epigenetic control of alternative mRNA processing at the imprinted Herc3/Nap1l5 locus.

40(18), 8917–8926.

Protection against De Novo Methylation Is Instrumental in Maintaining Parent-of-Origin Methylation Inherited from the Gametes

Molecular Cell, 47(6), 909–920.

Resetting for the Next Generation

Molecular Cell, 48(6), 819–821.

Distinct physiological and behavioural functions for parental alleles of imprinted Grb10

Nature, 469(7331), 534–538.

Human imprinted retrogenes exhibit non-canonical imprint chromatin signatures and reside in non-imprinted host genes.

Nucleic Acids Research, 39(11), 4577–4586.

Short interspersed element (SINE) depletion and long interspersed element (LINE) abundance are not features universally required for imprinting.

PloS One, 6(4), 18953.

Maternally-inherited Grb10 reduces placental size and efficiency

Developmental Biology, 337(1), 1–8.

Retrotransposition and genomic imprinting.

9(4), 340–346.