Megan A Cullen

Works (3)

Updated: July 5th, 2023 15:29

2019 journal article

A Fixed-Depth Microneedle Enhances Reproducibility and Safety for Corneal Gene Therapy

CORNEA, 39(3), 362–369.

By: B. Gilger n , E. Crabtree  n, L. Song *, T. Llanga*, M. Cullen n, A. Blanchard n, J. Salmon n, S. Patel, V. Zarnitsyn, M. Hirsch*

author keywords: cornea; stromal; gene therapy; safety
MeSH headings : Animals; Corneal Stroma / metabolism; Dependovirus / genetics; Gene Expression; Gene Transfer Techniques; Genetic Therapy / methods; Genetic Vectors; Green Fluorescent Proteins / genetics; Injections, Intraocular; Male; Microscopy, Confocal; Needles; Rabbits; Reproducibility of Results; Swine; Ultrasonography
TL;DR: This research presents a novel probabilistic approach that allows us to assess the importance of knowing the carrier and removal status of canine coronavirus as a source of infection in animals and its role in the immune system is investigated. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 18, 2020

2019 journal article

AAV-mediated expression of HLA-G1/5 reduces severity of experimental autoimmune uveitis

Scientific Reports, 9(1), 19864.

By: E. Crabtree  n, L. Song *, T. Llanga*, J. Bower *, M. Cullen n, J. Salmon n, M. Hirsch*, B. Gilger n 

MeSH headings : Animals; Antibodies, Neutralizing / metabolism; Dependovirus / genetics; Female; Genetic Therapy; HLA-G Antigens / genetics; HLA-G Antigens / metabolism; HLA-G Antigens / physiology; Intravitreal Injections; Rats; Uveitis / genetics; Uveitis / metabolism; Uveitis / pathology; Uveitis / therapy
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: February 10, 2020

2019 journal article

Multi-locus DNA sequence analysis, antifungal agent susceptibility, and fungal keratitis outcome in horses from Southeastern United States

PLOS ONE, 14(3), e0214214.

By: M. Cullen n, M. Jacob n, V. Cornish n , I. VanderSchel  n, H. Cotter n, M. Cubeta n , I. Carbone n , B. Gilger n 

Ed(s): O. Kniemeyer

MeSH headings : Animals; Antifungal Agents / pharmacology; Eye Infections, Fungal / drug therapy; Eye Infections, Fungal / microbiology; Eye Infections, Fungal / veterinary; Horse Diseases / drug therapy; Horse Diseases / microbiology; Horses; Keratitis / drug therapy; Keratitis / microbiology; Keratitis / veterinary; Southeastern United States; Species Specificity; Thiabendazole / pharmacology
TL;DR: The results of this study suggest that treatment of equine FK with antifungal agents requires accurate fungal species identification, and demonstrate the importance of fungal identification to the species rather than genus level. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: April 15, 2019

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