@article{poole_mayberry_newsome_poole_galliou_khanal_poore_serao_2020, title={Evaluation of Resistance to Fescue Toxicosis in Purebred Angus Cattle Utilizing Animal Performance and Cytokine Response}, volume={12}, ISSN={["2072-6651"]}, DOI={10.3390/toxins12120796}, abstractNote={Fescue toxicosis is a multifaceted syndrome common in cattle grazing endophyte-infected tall fescue; however, varying symptomatic responses potentially imply genetic tolerance to the syndrome. It was hypothesized that a subpopulation of animals within a herd would develop tolerance to ergot alkaloid toxicity. Therefore, the goals of this study were to develop selection criteria to identify tolerant and susceptible animals within a herd based on animal performance, and then examine responsive phenotypic and cytokine profiles to fescue toxicosis. Angus cows grazed endophyte-infected tall fescue at two locations for 13 weeks starting in mid-April 2016. Forage measurements were collected to evaluate ergot alkaloid exposure during the study. A post hoc analysis of animal performance was utilized to designate cattle into either tolerant or susceptible groups, and weekly physiological measurements and blood samples were collected to evaluate responses to chronic exposure to endophyte-infected tall fescue. Findings from this study support the proposed fescue toxicosis selection method formulated herein, could accurately distinguish between tolerant and susceptible animals based on the performance parameters in cattle chronically exposed to ergot alkaloids, and provides evidence to warrant additional analysis to examine the impact of ergot alkaloids on immune responsiveness in cattle experiencing fescue toxicosis.}, number={12}, journal={TOXINS}, author={Poole, Daniel H. and Mayberry, Kyle J. and Newsome, McKayla and Poole, Rebecca K. and Galliou, Justine M. and Khanal, Piush and Poore, Matthew H. and Serao, Nick V. L.}, year={2020}, month={Dec} }
 @article{mayberry_poole_newsome_khanal_poore_serao_poole_2019, title={Evaluation of cytokine response as an indicator of genetic resistance to fescue toxicosis in purebred Angus cattle.}, volume={97}, ISSN={["1525-3163"]}, DOI={10.1093/jas/skz053.102}, abstractNote={Abstract}, journal={JOURNAL OF ANIMAL SCIENCE}, author={Mayberry, Kyle and Poole, Rebecca K. and Newsome, McKayla A. and Khanal, Piush and Poore, Matthew H. and Serao, Nick V. L. and Poole, Daniel H.}, year={2019}, month={Jul}, pages={45–46} }
 @article{jackson_newsome_brown_poole_dudley_poore_poole_2019, title={Long term impact of ergot alkaloids on fetal heifer development and subsequent growth and reproductive performance.}, volume={97}, ISSN={["1525-3163"]}, DOI={10.1093/jas/skz053.103}, abstractNote={Abstract}, journal={JOURNAL OF ANIMAL SCIENCE}, author={Jackson, McKenzie Lane and Newsome, McKayla A. and Brown, Alecia R. and Poole, Rebecca K. and Dudley, Harrison B. and Poore, Matthew H. and Poole, Daniel H.}, year={2019}, month={Jul}, pages={46–46} }
 @article{smith_poole_mayberry_newsome_dudley_poole_2019, title={Timing of progesterone exposure effects pregnancy rates following fixed time artificial insemination in postpartum beef cows.}, volume={97}, ISSN={["1525-3163"]}, DOI={10.1093/jas/skz053.098}, abstractNote={Abstract}, journal={JOURNAL OF ANIMAL SCIENCE}, author={Smith, Anna L. and Poole, Rebecca K. and Mayberry, Kyle and Newsome, McKayla A. and Dudley, Harrison B. and Poole, Daniel H.}, year={2019}, month={Jul}, pages={43–44} }
 @article{smith_poole_mayberry_newsome_dudley_poole_2019, title={Timing of progesterone exposure effects pregnancy rates following fixed timed artificial insemination in postpartum beef cows.}, volume={97}, ISSN={["1525-3163"]}, DOI={10.1093/jas/skz053.195}, abstractNote={Abstract}, journal={JOURNAL OF ANIMAL SCIENCE}, author={Smith, Anna L. and Poole, Rebecca K. and Mayberry, Kyle and Newsome, McKayla A. and Dudley, Harrison B. and Poole, Daniel H.}, year={2019}, month={Jul}, pages={85–85} }
 @article{newsome_monn_mayberry_poole_young_poore_poole_2018, title={Grazing Novel or Endophyte-Infected Tall Fescue during Mid-Gestation Impacts Cow Performance.}, volume={96}, ISSN={["1525-3163"]}, DOI={10.1093/jas/sky027.025}, abstractNote={Consumption of endophyte-infected tall fescue results in poor reproductive performance. The objective of this study was to examine physiological changes in pregnant cows grazing tall fescue to develop a better understanding of the factors that contribute to the poor reproductive performance attributed to fescue toxicosis. Pregnant Angus and Simmental-Angus cows were blocked by age (2–3, 4–7, and >7 y), BW, and breed; and then randomly assigned to graze either novel (E-; <5% infection rate; n=27) or endophyte-infected tall fescue (E+; 79.5% infection rate; n=27). Weekly BW, BCS, hair coat scores (HCS), and hair shedding scores (HSS) were collected from mid-April through July when ergot alkaloid concentrations are greatest in the forage. Blood samples were collected to measure progesterone concentrations. Forage samples were taken every 2 wks to determine forage quality and composition. Data were analyzed using the MIXED procedure of SAS with repeated measures examined for effects of age, treatment (E- or E+) and time. Statistical significance was determined at P<0.05 and a tendency at 0.05<P<0.10. Pastures consisted of 69% and 67.5% available fescue for the novel and endophyte infected pastures, respectively. Average daily gain tended to be higher in E- cows than E+ (0.16, 0.01 kg/d, respectively; P=0.09). Cows on E- pastures had greater BCS compared to cows on E+ pastures (6.09, 5.77, respectively; P<0.05). Similarly, an age effect was observed with mature (4–7 and >7 y) cows having higher scores when compared to younger cows (6.0, 6.1, and 5.7, respectively; P<0.05). The HCS and HSS were greater in cows on E+ pastures compared to cows on E- pastures (P<0.05). The HSS were greater in the >7 y cows (2.69) compared to other age groups (2.40, 2.51, for 2–3 and 4–7 y, respectively, P<0.05) on E+ pastures, whereas no age differences in HCS were observed in cows on E- pastures. By d21 of the grazing period, cows on E- pastures displayed a greater ability to shed hair compared to cattle on E+ pastures (P<0.0001), which continued throughout the remainder of the grazing period. Progesterone concentrations in E+ cows (3.75 ng/ml) were decreased throughout the grazing period compared to E- cows (6.53 ng/mL, P<0.05). The impact of reduced progesterone concentrations, greater HCS and HSS and tendency for decreased ADG in cows grazing E+ during mid-gestation, compared to cows grazing E-, on calf development remains unknown.}, journal={JOURNAL OF ANIMAL SCIENCE}, author={Newsome, M. A. and Monn, R. E. and Mayberry, K. and Poole, R. K. and Young, Z. and Poore, M. H. and Poole, D. H.}, year={2018}, month={Mar}, pages={13–13} }