Mandy Ashton Womble

Works (14)

Updated: April 5th, 2024 06:29

2023 article

Bilateral patellar aplasia in a foal

Ludwig, E. K., Hallowell, K., Womble, M., & O'Neil, E. (2023, February 3). VETERINARY MEDICINE AND SCIENCE.

By: E. Ludwig n, K. Hallowell n, M. Womble n & E. O'Neil n

author keywords: aplasia; congenital; foal; horse; patella
MeSH headings : Animals; Horses; Male; Patella / diagnostic imaging; Patella / abnormalities; Patella / pathology; Hindlimb; Animals, Domestic; Horse Diseases / pathology
TL;DR: Bilateral congenital patellar aplasia has not been previously described in foals and post‐mortem examination identified a congenital malformation of both patella bones with failure of ossification and cardiac changes suggestive of right atrioventricular valve dysplasia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 27, 2023

2023 journal article

Pancreatic Torsion Resulting in Acute Pancreatic Necrosis in a Young Dog

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 59(6), 297–301.

By: R. Multani*, E. Cohen* , J. Haas n, L. Borst n , M. Womble n & S. Musulin n 

TL;DR: A case of 7 mo old French bulldog referred to North Carolina State University Small Animal Emergency and Triage Services because of acute abdomen, regurgitation, lethargy, and fever showed pathological changes that were supportive of a left-limb pancreatic torsion that was confirmed postmortem. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 11, 2023

2023 article

Severe bronchiectasis resulting from chronic bacterial bronchitis and bronchopneumonia in a jungle cat

Kang, D., Womble, M., Cullen, J. M., Harrison, T. M., Premanandan, C., & Schreeg, M. E. (2023, November 28). JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, Vol. 11.

By: D. Kang*, M. Womble n, J. Cullen n, T. Harrison n , C. Premanandan* & M. Schreeg n

author keywords: Escherichia coli; exotic animal; Felidae; lung; Proteus; respiratory disease; zoo animal
TL;DR: Chronic bronchitis and bronchopneumonia should be considered as a cause of bronchiectasis and a differential diagnosis for respiratory disease in non-domestic felids. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 18, 2023

2023 article

What is your diagnosis? Ulcerative shell lesions from a diamond-backed terrapin (Malaclemys terrapin)

Hastain, S. A. A., Buchy, J. M. M., Dombrowski, D. S. S., Womble, M. A. A., Armwood, A. R. R., & Gruber, E. J. J. (2023, July 27). VETERINARY CLINICAL PATHOLOGY, Vol. 7.

By: S. Hastain n, J. Buchy n, D. Dombrowski*, M. Womble n, A. Armwood n  & E. Gruber n 

UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 28, 2023

2022 journal article

Case Report: Novel Disseminated Paecilomyces formosus Infection in a Dog

FRONTIERS IN VETERINARY SCIENCE, 9.

By: S. Anderson  n, D. Murillo *, M. Womble n, N. Gibbs n, K. Harrell n  & T. Watanabe  n

author keywords: Paecilomyces formosus; hyalohyphomycosis; systemic mycosis; domestic animal; dog
TL;DR: To the authors' knowledge, this is the first case of disseminated paecilomycosis caused by P. formosus infection in a dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 13, 2022

2022 article

Outbreak in African lions of Yersinia pseudotuberculosis infection, with aberrant bacterial morphology

Womble, M., Cabot, M. L., Harrison, T., & Watanabe, T. T. N. (2022, January 17). JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, Vol. 1.

By: M. Womble n, M. Cabot n, T. Harrison n  & T. Watanabe  n

author keywords: atypical bacteria; Felidae; lions; Yersinia pseudotuberculosis; yersiniosis
MeSH headings : Animals; Disease Outbreaks / veterinary; Female; Lions; Male; Spleen / pathology; Yersinia pseudotuberculosis; Yersinia pseudotuberculosis Infections / epidemiology; Yersinia pseudotuberculosis Infections / microbiology; Yersinia pseudotuberculosis Infections / veterinary
TL;DR: Histologic examination identified lytic, necrosuppurative foci in the liver, spleen, lungs, and kidney, with abundant intralesional gram-negative coccobacilli in the male lion and similar findings were seen in the female lion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: February 7, 2022

2022 journal article

YERSINIA PSEUDOTUBERCULOSIS INFECTION IN LIONS (PANTHERA LEO) AT A ZOOLOGICAL PARK

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 53(3), 593–599.

By: M. Cabot*, T. Watanabe, M. Womble* & T. Harrison* 

MeSH headings : Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents / therapeutic use; Cefazolin; Enrofloxacin; Female; Lions; Male; Yersinia pseudotuberculosis
TL;DR: Postmortem examination, microscopic evaluation, and bacterial culture of the liver from both deceased lions confirmed systemic Yersinia pseudotuberculosis infection, andceptibility testing revealed resistance to amoxicillin–clavulanic acid and cefazolin. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: November 14, 2022

2021 journal article

Concurrent Clostridial Enteritis and Oviductal Adenocarcinoma with Carcinomatosis in an Adult Alpaca (Vicugna pacos)

JOURNAL OF COMPARATIVE PATHOLOGY, 189, 52–58.

By: M. Womble n, M. Schreeg n, A. Hoch n, E. Meira n, D. Foster n , C. Premanandan*, T. Watanabe  n

author keywords: alpaca; Camelidae; Clostridium spp; oviductal adenocarcinoma
MeSH headings : Adenocarcinoma / veterinary; Animals; Camelids, New World; Enteritis / veterinary; Female; Peritoneal Neoplasms / veterinary; Polymerase Chain Reaction / veterinary
TL;DR: The prominent ciliated morphology of the neoplastic cells and the classification of human fallopian tube (oviduct) neoplasia lead us to propose oviductal adenocarcinoma with widespread carcinomatosis as the definitive diagnosis of an adult alpaca with a history of colic and anorexia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: December 13, 2021

2021 review

MORTALITY REVIEW FOR THE NORTH AMERICAN SNOW LEOPARD (PANTHERA UNCIA) ZOO POPULATION FROM JANUARY 1999 TO DECEMBER 2019

[Review of ]. JOURNAL OF ZOO AND WILDLIFE MEDICINE, 52(1), 145–156.

By: M. Womble*, T. Georoff, K. Helmick, N. Carpenter, J. Joslin, L. Tupa, J. Tetzloff, D. McAloose

MeSH headings : Aging; Animals; Animals, Zoo; Communicable Diseases / mortality; Communicable Diseases / veterinary; Felidae; Female; Inflammation / mortality; Inflammation / veterinary; Male; Mortality; Noncommunicable Diseases; North America; Retrospective Studies
TL;DR: Overall, noninfectious diseases were the most common COD across all age groups (73%) and in adult and geriatric snow leopards, chronic renal disease (CRD) and malignant neoplasia (19.7%), including oral squamous cell carcinoma (6.4%), were a common C OD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: May 24, 2021

2020 journal article

Pathologic Lesions of the Budgett Frog (Lepidobatrachus laevis), an Emerging Laboratory Animal Model

COMPARATIVE MEDICINE, 70(3), 239–247.

By: M. Womble n, G. Lewbart n  & H. Shive n

MeSH headings : Animal Experimentation; Animals; Anura; Developmental Biology; Female; Male; Models, Animal; Retrospective Studies
TL;DR: This retrospective analysis is the first description of histologic lesions identified in captive L. laevis populations, providing new insight into spontaneous disease processes occurring in this species for use in disease diagnosis and clinical management. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 26, 2020

2019 journal article

Radiographic anatomy and barium sulfate contrast study of the gastrointestinal tract of eastern box turtles (Terrapene carolina carolina)

VETERINARY RADIOLOGY & ULTRASOUND, 60(5), 473–484.

By: E. Houck n, E. Cohen n , M. Womble n, G. Lewbart n  & O. Petritz n 

author keywords: cecum; radiology; Testudines
MeSH headings : Animals; Barium Sulfate / analysis; Female; Gastrointestinal Tract / anatomy & histology; Gastrointestinal Tract / diagnostic imaging; Male; Prospective Studies; Radiography / veterinary; Reference Values; Turtles / anatomy & histology
TL;DR: A novel, horizontal beam, rostrocaudal view for gastrointestinal contrast studies in chelonians is introduced to serve as a reference on the gastrointestinal anatomy, transit, and emptying times in healthy eastern box turtles. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 7, 2019

2016 review

Frogs as integrative models for understanding digestive organ development and evolution

[Review of ]. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 51, 92–105.

By: M. Womble n, M. Pickett n & N. Nascone-Yoder n

author keywords: Embryo; Xenopus; Lepidobatrachus; Eleutherodactylous coqui; Gut; Specification; Morphogenesis; Evolution
MeSH headings : Animals; Biological Evolution; Calcium Signaling; Cell Communication; Digestive System / cytology; Digestive System / embryology; Endoderm / cytology; Endoderm / embryology; Gene Expression; Gene Expression Regulation, Developmental; Humans; Morphogenesis; Xenopus Proteins / genetics; Xenopus Proteins / metabolism; Xenopus laevis / embryology
TL;DR: The unparalleled experimental versatility of frog embryos make them excellent, integrative models for studying digestive organ development across multiple disciplines, including the regeneration or replacement of diseased organs, the etiology of digestive organ birth defects, and the evolution of specialized features of digestive anatomy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Budgett's frog (Lepidobatrachus laevis): A new amphibian embryo for developmental biology

DEVELOPMENTAL BIOLOGY, 405(2), 291–303.

By: N. Amin n, M. Womble n, C. Ledon-Rettig *, M. Hull n, A. Dickinson & N. Nascone-Yoder n

author keywords: Lepidobatrachus; Xenopus; Amphibian; Embryo; Stages; Scaling
MeSH headings : Amphibians; Animals; Anura / embryology; Cell Lineage; Developmental Biology; Embryonic Development; Immunohistochemistry; Models, Animal; Morphogenesis; Organogenesis; Regeneration; Species Specificity; Xenopus laevis / physiology
TL;DR: The Budgett's frog is described, an unusual species with eggs that are over twice the diameter of laboratory Xenopus, and embryos that can tolerate higher temperatures to develop into a tadpole four times more rapidly, which substantially accelerates the pace of experimentation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Morphogenesis of the Primitive Gut Tube Is Generated by Rho/ROCK/Myosin II-Mediated Endoderm Rearrangements

DEVELOPMENTAL DYNAMICS, 238(12), 3111–3125.

By: R. Reed n, M. Womble n, M. Dush n, R. Tull n, S. Bloom n, A. Morckel n, E. Devlin*, N. Nascone-Yoder n

author keywords: gut; Xenopus; morphogenesis; endoderm, intercalation; elongation
MeSH headings : Animals; Animals, Genetically Modified; Body Patterning / genetics; Cell Polarity / genetics; Cell Shape / genetics; Embryo, Nonmammalian; Endoderm / cytology; Endoderm / embryology; Endoderm / metabolism; Gastrointestinal Diseases / congenital; Gastrointestinal Diseases / embryology; Gastrointestinal Tract / abnormalities; Gastrointestinal Tract / embryology; Gastrula / embryology; Gastrula / metabolism; Models, Biological; Morphogenesis / genetics; Nonmuscle Myosin Type IIB / genetics; Nonmuscle Myosin Type IIB / metabolism; Nonmuscle Myosin Type IIB / physiology; Signal Transduction / genetics; Xenopus / embryology; Xenopus / genetics; Xenopus / metabolism; rho-Associated Kinases / genetics; rho-Associated Kinases / metabolism; rho-Associated Kinases / physiology; rhoA GTP-Binding Protein / genetics; rhoA GTP-Binding Protein / metabolism; rhoA GTP-Binding Protein / physiology
TL;DR: The results suggest that the cellular and molecular events driving tissue elongation in the PGT are mechanistically analogous to those that function during gastrulation, but occur within a novel cylindrical geometry to generate an epithelial‐lined tube. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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