Matthew Breen
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Works (117)
Updated: August 29th, 2023 11:23
2023 article
Defining the relevance of surgical margins. Part two: Strategies to improve prediction of recurrence risk
Bray, J., Eward, W., & Breen, M. (2023, February 15). VETERINARY AND COMPARATIVE ONCOLOGY.
co-author countries:
United States of America 🇺🇸
author keywords: genetics; pathology; small animal; surgical oncology; tumour biology
MeSH headings : Animals; Cats; Dogs; Margins of Excision; Neoplasm, Residual / pathology; Neoplasm, Residual / veterinary; Cat Diseases / surgery; Neoplasm Recurrence, Local / veterinary; Dog Diseases / surgery
Source: Web Of Science
Added: March 13, 2023
2023 journal article
Dirofilaria immitis Identified in Galapagos Sea Lions (Zalophus wollebaeki): A Wildlife Health and Conservation Concern
JOURNAL OF WILDLIFE DISEASES, 59(3), 487–494.
co-author countries:
Ecuador 🇪🇨 United States of America 🇺🇸
author keywords: Dirofilaria immitis; Galapagos Islands; heartworm; Zalophus wollebaeki
MeSH headings : Animals; Dogs; Male; Sea Lions; Dirofilaria immitis; Animals, Wild; Caniformia; Animals, Domestic; Endangered Species; Dirofilariasis / epidemiology; Dog Diseases
Sources: Web Of Science, ORCID
Added: August 14, 2023
2023 journal article
The dogs of Chernobyl: Demographic insights into populations inhabiting the nuclear exclusion zone
SCIENCE ADVANCES, 9(9).
co-author countries:
China 🇨🇳 Poland 🇵🇱 Ukraine 🇺🇦 United States of America 🇺🇸
MeSH headings : Dogs; Animals; Chernobyl Nuclear Accident; Environment; Disasters; Environmental Pollution; Demography
www.science.org (publisher PDF)
Source: Web Of Science
Added: April 4, 2023
2023 journal article
Whole exome sequencing analysis of canine urothelial carcinomas without BRAF V595E mutation: Short in-frame deletions in BRAF and MAP2K1 suggest alternative mechanisms for MAPK pathway disruption
PLOS GENETICS, 19(4).
co-author countries:
United States of America 🇺🇸
MeSH headings : Dogs; Animals; Humans; Urinary Bladder Neoplasms / genetics; Urinary Bladder Neoplasms / veterinary; Carcinoma, Transitional Cell / genetics; Carcinoma, Transitional Cell / veterinary; Proto-Oncogene Proteins B-raf / genetics; Exome Sequencing; Mutation; MAP Kinase Kinase 1 / genetics
Sources: Web Of Science, ORCID
Added: May 15, 2023
2022 article
Evaluating the relevance of surgical margins. Part one: The problems with current methodology
Bray, J., Eward, W., & Breen, M. (2022, November 25). VETERINARY AND COMPARATIVE ONCOLOGY.
co-author countries:
United States of America 🇺🇸
author keywords: genetics'; pathology; small animal; surgical oncology; tumour biology
MeSH headings : Animals; Margins of Excision; Neoplasm Recurrence, Local / veterinary; Retrospective Studies
Source: Web Of Science
Added: December 12, 2022
2022 article
Inter-pathologist agreement on diagnosis, classification and grading of canine glioma
Krane, G. A., Shockley, K. R., Malarkey, D. E., Miller, A. D., Miller, C. R., Tokarz, D. A., … Mariani, C. L. (2022, July 30). VETERINARY AND COMPARATIVE ONCOLOGY, Vol. 7.
co-author countries:
United States of America 🇺🇸
author keywords: brain; cancer; dog; histopathology; immunohistochemistry
MeSH headings : Humans; Animals; Dogs; Oligodendroglioma / diagnosis; Oligodendroglioma / veterinary; Oligodendroglioma / pathology; Pathologists; Dog Diseases / diagnosis; Dog Diseases / pathology; Glioma / diagnosis; Glioma / veterinary; Glioma / pathology; Astrocytoma / veterinary; Brain Neoplasms / diagnosis; Brain Neoplasms / veterinary; Brain Neoplasms / pathology
Sources: Web Of Science, ORCID
Added: August 8, 2022
2022 journal article
The AGMK1-9T7 cell model of neoplasia: Evolution of DNA copy-number aberrations and miRNA expression during transition from normal to metastatic cancer cells
PLOS ONE, 17(10).
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Humans; Chlorocebus aethiops; MicroRNAs / genetics; MicroRNAs / metabolism; Neoplasms / genetics; Carcinogenesis / genetics; DNA Copy Number Variations / genetics; Chromosome Aberrations; Neoplasms, Second Primary / genetics; DNA; Gene Expression Regulation, Neoplastic; Gene Expression Profiling
Source: Web Of Science
Added: February 27, 2023
2022 article
Transcriptome annotation reveals minimal immunogenetic diversity among Wyoming toads, Anaxyrus baxteri
Carlson, K. B., Wcisel, D. J., Ackerman, H. D., Romanet, J., Christiansen, E. F., Niemuth, J. N., … Yoder, J. A. (2022, April 28). CONSERVATION GENETICS, Vol. 4.
co-author countries:
United States of America 🇺🇸
author keywords: Amphibian; Bufonidae; Immunogenetics; MHC; TLR; Transcriptomics
Sources: Web Of Science, ORCID
Added: April 29, 2022
2021 article
Comparative Assessment of Pesticide Exposures in Domestic Dogs and Their Owners Using Silicone Passive Samplers and Biomonitoring
Wise, C. F., Hammel, S. C., Herkert, N. J., Ospina, M., Calafat, A. M., Breen, M., & Stapleton, H. M. (2021, December 29). ENVIRONMENTAL SCIENCE & TECHNOLOGY.
co-author countries:
United States of America 🇺🇸
author keywords: exposure; wristband; silicone; biomonitoring; pesticide; dog
MeSH headings : Animals; Biological Monitoring; Chlorpyrifos; Dogs; Environmental Exposure / analysis; Environmental Monitoring; Humans; Pesticides / analysis; Silicones
Source: Web Of Science
Added: January 18, 2022
2021 journal article
Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions
MOLECULAR CANCER RESEARCH, 19(5), 847–861.
co-author countries:
Canada 🇨🇦 Sweden 🇸🇪 United States of America 🇺🇸
MeSH headings : Animals; Dog Diseases / genetics; Dogs; Gene Expression Profiling / methods; Gene Fusion; Genomics / methods; Hemangiosarcoma / genetics; Humans; Transcription, Genetic; Vascular Neoplasms / genetics
Source: Web Of Science
Added: June 10, 2021
2021 article
Hi-C scaffolded short- and long-read genome assemblies of the California sea lion are broadly consistent for syntenic inference across 45 million years of evolution
Peart, C. R., Williams, C., Pophaly, S. D., Neely, B. A., Gulland, F. M. D., Adams, D. J., … Wolf, J. B. W. (2021, June 27). MOLECULAR ECOLOGY RESOURCES.
co-author countries:
Germany 🇩🇪 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: California sea lion (Zalophus californianus); cancer; Carnivora; chromatin interaction mapping; genome assembly; genome evolution; Hi-C
MeSH headings : Animals; Dogs; Ferrets; Genome; Sea Lions / genetics; Synteny; X Chromosome
Source: Web Of Science
Added: July 6, 2021
2021 journal article
Phase I/II Trial of Vemurafenib in Dogs with Naturally Occurring, BRAF-mutated Urothelial Carcinoma
MOLECULAR CANCER THERAPEUTICS, 20(11), 2177–2188.
co-author countries:
Switzerland 🇨🇭 United States of America 🇺🇸
MeSH headings : Adolescent; Animals; Carcinoma, Transitional Cell / drug therapy; Carcinoma, Transitional Cell / pathology; Child; Disease Models, Animal; Dogs; Humans; Mutation; Proto-Oncogene Proteins B-raf / drug effects; Vemurafenib / pharmacology; Vemurafenib / therapeutic use
Source: Web Of Science
Added: November 23, 2021
2021 journal article
Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species
PLOS COMPUTATIONAL BIOLOGY, 17(9).
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Biomarkers, Tumor / genetics; Bone Neoplasms / genetics; Bone Neoplasms / veterinary; Computational Biology; Dog Diseases / classification; Dog Diseases / genetics; Dogs; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Lung Neoplasms / genetics; Lung Neoplasms / veterinary; Lymphoma, B-Cell / genetics; Lymphoma, B-Cell / veterinary; Lymphoma, T-Cell / genetics; Lymphoma, T-Cell / veterinary; Melanoma / genetics; Melanoma / veterinary; Molecular Sequence Annotation; Molecular Targeted Therapy; Neoplasms / classification; Neoplasms / genetics; Neoplasms / veterinary; Oncogenes; Osteosarcoma / genetics; Osteosarcoma / veterinary; Species Specificity; Translational Research, Biomedical
Source: Web Of Science
Added: February 21, 2022
2020 article
A comparative oncology approach to biomarker and drug discovery for cancer diagnosis and treatment in dogs and humans
LeBlanc, A. K., Mazcko, C. N., Breen, M., Thomas, R., & Thamm, D. H. (2020, August). CANCER RESEARCH, Vol. 80.
Source: Web Of Science
Added: March 8, 2021
2020 journal article
Comparative Exposure Assessment Using Silicone Passive Samplers Indicates That Domestic Dogs Are Sentinels To Support Human Health Research
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 54(12), 7409–7419.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Biomarkers; Dogs; Environmental Monitoring; Humans; Organophosphates; Silicones
Source: Web Of Science
Added: July 13, 2020
2020 journal article
Development of a Genome-Wide Oligonucleotide Microarray Platform for Detection of DNA Copy Number Aberrations in Feline Cancers
VETERINARY SCIENCES, 7(3).
co-author countries:
United States of America 🇺🇸
author keywords: feline; cat; cancer; genomics; chromosome; comparative genomic hybridization (CGH)
Sources: Web Of Science, ORCID
Added: November 9, 2020
2020 article
Molecular mechanisms that activate convergent oncogenic pathway in genomically complex angiosarcoma
Kim, J. H., Megquier, K., Sarver, A. L., Thomas, R., Schulte, A. J., Wang, C., … Modiano, J. F. (2020, August). CANCER RESEARCH, Vol. 80.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
Source: Web Of Science
Added: March 8, 2021
2020 journal article
PTPN11mutations in canine and human disseminated histiocytic sarcoma
INTERNATIONAL JOURNAL OF CANCER, 147(6), 1657–1665.
co-author countries:
Germany 🇩🇪 France 🇫🇷 United States of America 🇺🇸
author keywords: histiocytic sarcoma; dog; spontaneous model; PTPN11
MeSH headings : Adult; Aged; Aged, 80 and over; Animals; Biopsy; Cell Line, Tumor; Cell Proliferation / drug effects; Child; Child, Preschool; DNA Mutational Analysis; Disease Models, Animal; Dog Diseases / blood; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Drug Screening Assays, Antitumor / methods; Female; Histiocytes / pathology; Histiocytic Sarcoma / drug therapy; Histiocytic Sarcoma / genetics; Histiocytic Sarcoma / pathology; Histiocytic Sarcoma / veterinary; Humans; Infant; MAP Kinase Signaling System / drug effects; MAP Kinase Signaling System / genetics; Male; Middle Aged; Mitogen-Activated Protein Kinases / antagonists & inhibitors; Mitogen-Activated Protein Kinases / metabolism; Mutation; Protein Kinase Inhibitors / pharmacology; Protein Kinase Inhibitors / therapeutic use; Protein Tyrosine Phosphatase, Non-Receptor Type 11 / antagonists & inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 11 / genetics; Ribonucleases; Tumor Suppressor Proteins; Young Adult
Source: Web Of Science
Added: August 10, 2020
2020 journal article
Use of standardized bioinformatics for the analysis of fungal DNA signatures applied to sample provenance
FORENSIC SCIENCE INTERNATIONAL, 310.
co-author countries:
United States of America 🇺🇸
author keywords: Forensic microbiology; Bioinformatics; Metabarcoding; Sample provenance
MeSH headings : DNA Barcoding, Taxonomic; DNA, Fungal / chemistry; Demography; Forensic Sciences; Fungi; Humans; Reference Values; Soil
Sources: Web Of Science, ORCID
Added: May 26, 2020
2019 journal article
Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma
MOLECULAR CANCER RESEARCH, 17(12), 2410–2421.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
MeSH headings : Animals; Blood Vessels / pathology; Breast / metabolism; Breast / pathology; Class I Phosphatidylinositol 3-Kinases / genetics; Class Ia Phosphatidylinositol 3-Kinase / genetics; Cyclin-Dependent Kinase Inhibitor p15 / genetics; Cyclin-Dependent Kinase Inhibitor p16 / genetics; Dogs; Female; Genome / genetics; Genomics; Hemangiosarcoma / genetics; Hemangiosarcoma / pathology; Humans; Mutation / genetics; Tumor Suppressor Protein p53 / genetics; Viscera / metabolism; Viscera / pathology; Exome Sequencing
Sources: Web Of Science, ORCID
Added: December 30, 2019
2019 journal article
Genome-wide DNA copy number analysis and targeted transcriptional analysis of canine histiocytic malignancies identifies diagnostic signatures and highlights disruption of spindle assembly complex
CHROMOSOME RESEARCH, 27(3), 179–202.
co-author countries:
United States of America 🇺🇸
author keywords: Histiocytic sarcoma; Chromothripsis; MMP9; Aurora kinase; Dendritic cell sarcoma
MeSH headings : Animals; Chromosome Disorders; DNA Copy Number Variations / genetics; Dog Diseases / diagnosis; Dog Diseases / genetics; Dogs; Gene Expression Profiling; Genome / genetics; Histiocytic Disorders, Malignant / diagnosis; Histiocytic Disorders, Malignant / genetics; Histiocytic Disorders, Malignant / veterinary; Humans; Immunohistochemistry / methods; Matrix Metalloproteinase 9 / metabolism; Spindle Apparatus / pathology
Source: Web Of Science
Added: September 30, 2019
2019 journal article
Lack of influence by endosymbiont Wolbachia on virus titer in the common bed bug, Cimex lectularius
Parasites & Vectors, 12(1).
co-author countries:
United States of America 🇺🇸
author keywords: Cimex lectularius; Wolbachia; Endosymbiont; Cimicidae; Virus suppression; ssRNA
MeSH headings : Animals; Bedbugs / microbiology; Bedbugs / virology; Calicivirus, Feline / growth & development; Calicivirus, Feline / isolation & purification; Microbial Interactions; Viral Load; Wolbachia / growth & development
Sources: Web Of Science, ORCID, Crossref
Added: September 30, 2019
2019 journal article
Novel Noninvasive Diagnostics
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE, 49(5), 781-+.
co-author countries:
United States of America 🇺🇸
author keywords: Canine; Cancer; Liquid biopsy; Bladder; Prostate; BRAF; Lymphoma
MeSH headings : Animals; Carcinoma, Transitional Cell / diagnosis; Carcinoma, Transitional Cell / genetics; Carcinoma, Transitional Cell / veterinary; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / genetics; Dogs; Early Detection of Cancer / methods; Early Detection of Cancer / veterinary; Female; Humans; Leukemia / diagnosis; Leukemia / veterinary; Liquid Biopsy / methods; Liquid Biopsy / veterinary; Lymphoma / diagnosis; Lymphoma / drug therapy; Lymphoma / veterinary; Male; Molecular Targeted Therapy / veterinary; Mutation; Neoplasms / diagnosis; Neoplasms / drug therapy; Neoplasms / genetics; Neoplasms / veterinary; Urethral Neoplasms / diagnosis; Urethral Neoplasms / genetics; Urethral Neoplasms / veterinary; Urinary Bladder Neoplasms / veterinary
Source: Web Of Science
Added: September 16, 2019
2018 journal article
A comprehensive genomic history of extinct and living elephants
Proceedings of the National Academy of Sciences, 115(11), E2566–E2574.
co-author countries:
Austria 🇦🇹 Australia 🇦🇺 Canada 🇨🇦 Switzerland 🇨🇭 Germany 🇩🇪 Denmark 🇩🇰 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Sweden 🇸🇪 United States of America 🇺🇸
author keywords: paleogenomics; elephantid evolution; mammoth; admixture; species divergence
MeSH headings : Animals; Elephants / classification; Elephants / genetics; Evolution, Molecular; Extinction, Biological; Fossils; Gene Flow; Genome; Genomics / history; History, Ancient; Mammoths / classification; Mammoths / genetics; Mastodons / classification; Mastodons / genetics; Phylogeny
Source: Crossref
Added: February 21, 2020
2018 article
Comparative genomic analyses of osteosarcoma etiology reveal a chromosomal structural rationale for the increased incidence of osteosarcoma in dogs
Sarver, A. L., Mills, L., Temiz, N., Scott, M. I., Sarver, A., Spector, L., … Largaespada, D. (2018, July). CANCER RESEARCH, Vol. 78.
co-author countries:
United States of America 🇺🇸
Source: Web Of Science
Added: June 24, 2019
2018 journal article
Growth kinetics of endosymbiont Wolbachia in the common bed bug, Cimex lectularius
Scientific Reports, 8(1).
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Bedbugs / microbiology; DNA / genetics; Female; Kinetics; Larva / microbiology; Symbiosis; Wolbachia / growth & development
Sources: Crossref, ORCID
Added: December 30, 2019
2018 article
Mutational and transcriptomic profiling identify distinct angiogenic and inflammatory subtypes of angiosarcoma
Kim, J. H., Megquier, K., Sarver, A. L., Thomas, R., Wang, C., Elvers, I., … Modiano, J. F. (2018, July). CANCER RESEARCH, Vol. 78.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
Source: Web Of Science
Added: June 24, 2019
2018 journal article
Relationship Between Sequence Homology, Genome Architecture, and Meiotic Behavior of the Sex Chromosomes in North American Voles
GENETICS, 210(1), 83–97.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: pseudoautosomal region; Microtus heterochromatin; telomeric repeats; meiotic synapsis
MeSH headings : Animals; Arvicolinae / genetics; Chromosome Segregation / genetics; Genomics / methods; Meiosis / genetics; North America; Pseudoautosomal Regions / genetics; Sequence Analysis, DNA / methods; Sequence Homology, Nucleic Acid; Sex Chromosomes / genetics; Telomere / genetics; Telomere-Binding Proteins / genetics; X Chromosome / genetics; Y Chromosome / genetics
Source: Web Of Science
Added: October 19, 2018
2018 journal article
Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis
PLOS GENETICS, 14(9).
co-author countries:
Australia 🇦🇺 United States of America 🇺🇸
Source: Web Of Science
Added: October 16, 2018
2017 journal article
Association of breed and histopathological grade in canine mast cell tumours
VETERINARY AND COMPARATIVE ONCOLOGY, 15(3), 829–839.
co-author countries:
United States of America 🇺🇸
author keywords: Boxer; dog; epidemiology; genetics; MCT; Pug
MeSH headings : Age Factors; Animals; Dog Diseases / etiology; Dog Diseases / pathology; Dogs; Female; Male; Mastocytosis, Cutaneous / etiology; Mastocytosis, Cutaneous / pathology; Mastocytosis, Cutaneous / veterinary; Retrospective Studies; Risk Factors; Sex Factors; Skin Neoplasms / etiology; Skin Neoplasms / pathology; Skin Neoplasms / veterinary; Species Specificity
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Constitutive activation of alternative nuclear factor kappa B pathway in canine diffuse large B-cell lymphoma contributes to tumor cell survival and is a target of new adjuvant therapies
LEUKEMIA & LYMPHOMA, 58(7), 1702–1710.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
author keywords: Diffuse large B-cell lymphoma; alternative NF-kappa B pathway; canine model; targeting therapy; comparative pathology
MeSH headings : Animals; Antineoplastic Agents / pharmacology; Cell Line, Tumor; Cell Survival / drug effects; Disease Models, Animal; Dogs; Gene Expression; Genes, Reporter; Humans; Lymphoma, Large B-Cell, Diffuse / drug therapy; Lymphoma, Large B-Cell, Diffuse / metabolism; Lymphoma, Large B-Cell, Diffuse / pathology; Molecular Targeted Therapy; NF-kappa B / metabolism; Signal Transduction / drug effects
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Evaluation of gene expression and DNA copy number profiles of adipose tissue-derived stromal cells and consecutive neurosphere-like cells generated from dogs with naturally occurring spinal cord injury
American Journal of Veterinary Research, 78(3), 371–380.
MeSH headings : Adipose Tissue / cytology; Animals; Cells, Cultured; Comparative Genomic Hybridization; Dogs; Female; Gene Dosage / genetics; Gene Expression Profiling; Gene Expression Regulation; Male; Neural Stem Cells / cytology; Neural Stem Cells / pathology; Neurons / cytology; Neurons / pathology; Proteins / genetics; Spinal Cord Injuries / physiopathology; Spinal Cord Injuries / veterinary; Stromal Cells / cytology; Stromal Cells / physiology
Sources: NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2017 journal article
Generation of LIF-independent induced pluripotent stem cells from canine fetal fibroblasts
Theriogenology, 92, 75–82.
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
author keywords: iPSC; Canine; Stem cells; Pluripotency; Cellular reprogramming
MeSH headings : Animals; Dogs; Fetus / cytology; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / physiology; Gene Expression Regulation / physiology; Leukemia Inhibitory Factor / pharmacology; Mice; Mice, Inbred BALB C; Mice, Nude; Pluripotent Stem Cells / physiology; Polymerase Chain Reaction / veterinary
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Genomic profiling of canine mast cell tumors identifies DNA copy number aberrations associated with KIT mutations and high histological grade
CHROMOSOME RESEARCH, 25(2), 129–143.
co-author countries:
United States of America 🇺🇸
author keywords: Cancer; Comparative genomic hybridization; Digital PCR; Dog; Mastocytosis; Pug
MeSH headings : Animals; Comparative Genomic Hybridization; DNA Copy Number Variations / genetics; Dogs; Genome / genetics; Mastocytosis, Cutaneous / diagnosis; Mastocytosis, Cutaneous / genetics; Mastocytosis, Cutaneous / pathology; Mutation; Predictive Value of Tests; Proto-Oncogene Proteins c-kit / genetics; Sensitivity and Specificity
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Integrated immunohistochemical and DNA copy number profiling analysis provides insight into the molecular pathogenesis of canine follicular lymphoma
VETERINARY AND COMPARATIVE ONCOLOGY, 15(3), 852–867.
co-author countries:
United States of America 🇺🇸
author keywords: BCL2; canine; comparative genomic hybridization; fluorescence in situ hybridization; follicular lymphoma; immunohistochemistry
MeSH headings : Animals; DNA Copy Number Variations / genetics; DNA Fingerprinting / veterinary; Dog Diseases / etiology; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Genome-Wide Association Study / veterinary; Lymphoma, Follicular / etiology; Lymphoma, Follicular / genetics; Lymphoma, Follicular / pathology; Lymphoma, Follicular / veterinary; Male; Risk Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Interactions between CXCR4 and CXCL12 promote cell migration and invasion of canine hemangiosarcoma
VETERINARY AND COMPARATIVE ONCOLOGY, 15(2), 315–327.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
author keywords: canine hemangiosarcoma; CXCR4; CXCL12; invasion; migration
MeSH headings : Animals; Cell Line, Tumor; Cell Movement / physiology; Chemokine CXCL12 / physiology; Dog Diseases / pathology; Dogs; Flow Cytometry / veterinary; Gene Expression Profiling / veterinary; Gene Expression Regulation, Neoplastic / physiology; Hemangiosarcoma / pathology; Hemangiosarcoma / veterinary; Neoplasm Invasiveness / pathology; Receptors, CXCR4 / physiology
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Intracoronary allogeneic cardiosphere-derived stem cells are safe for use in dogs with dilated cardiomyopathy
Journal of Cellular and Molecular Medicine, 21(8), 1503–1512.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: cardiosphere-derived cells; dogs; dilated cardiomyopathy; stem cell therapy; allogeneic
MeSH headings : Animals; Biomarkers / metabolism; Cardiomyopathy, Dilated / diagnostic imaging; Cardiomyopathy, Dilated / immunology; Cardiomyopathy, Dilated / pathology; Cardiomyopathy, Dilated / therapy; Coronary Vessels / cytology; Coronary Vessels / immunology; Dogs; Echocardiography; Endoglin / genetics; Endoglin / immunology; Female; Gene Expression; Humans; Male; Myocardium / immunology; Myocardium / pathology; Proto-Oncogene Proteins c-kit / genetics; Proto-Oncogene Proteins c-kit / immunology; Spheroids, Cellular / cytology; Spheroids, Cellular / immunology; Spheroids, Cellular / transplantation; Stem Cell Transplantation; Stem Cells / cytology; Stem Cells / immunology; Thy-1 Antigens / genetics; Thy-1 Antigens / immunology; Transplantation, Homologous
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2017 journal article
Malignant canine mammary tumours: Preliminary genomic insights using oligonucleotide array comparative genomic hybridisation analysis
VETERINARY JOURNAL, 222, 68–71.
co-author countries:
Portugal 🇵🇹 United States of America 🇺🇸
author keywords: Array comparative genomic hybridisation; Canine mammary tumours; Chromosome; Genetics
MeSH headings : Animals; Comparative Genomic Hybridization / veterinary; DNA Copy Number Variations; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Mammary Neoplasms, Animal / genetics; Mammary Neoplasms, Animal / pathology
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Sequence analysis of RAS and RAF mutation hot spots in canine carcinoma
VETERINARY AND COMPARATIVE ONCOLOGY, 15(4), 1598–1605.
co-author countries:
United States of America 🇺🇸
author keywords: bladder; cancer; dog; prostate; squamous cell carcinoma; transitional cell carcinoma
MeSH headings : Animals; Dog Diseases / genetics; Dogs; Genes, ras / genetics; Mutation / genetics; Neoplasms / genetics; Neoplasms / veterinary; Proto-Oncogene Proteins B-raf / genetics; Sequence Analysis, DNA / veterinary
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Comprehensive genomic characterization of five canine lymphoid tumor cell lines
BMC Veterinary Research, 12.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Detection of Copy Number Imbalance in Canine Urothelial Carcinoma With Droplet Digital Polymerase Chain Reaction
VETERINARY PATHOLOGY, 53(4), 764–772.
co-author countries:
United States of America 🇺🇸
author keywords: comparative genomic hybridization; cytogenetics; dogs; molecular diagnostic; transitional cell carcinoma; polymerase chain reaction; urinary bladder; urothelial carcinoma
MeSH headings : Animals; Carcinoma, Transitional Cell / diagnosis; Carcinoma, Transitional Cell / genetics; Carcinoma, Transitional Cell / pathology; Carcinoma, Transitional Cell / veterinary; Comparative Genomic Hybridization / veterinary; DNA Copy Number Variations; Dog Diseases / diagnosis; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Polymerase Chain Reaction / veterinary; Urinary Bladder / pathology; Urinary Bladder Neoplasms / diagnosis; Urinary Bladder Neoplasms / genetics; Urinary Bladder Neoplasms / pathology; Urinary Bladder Neoplasms / veterinary; Urologic Neoplasms / diagnosis; Urologic Neoplasms / genetics; Urologic Neoplasms / pathology; Urologic Neoplasms / veterinary
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity
CHROMOSOME RESEARCH, 23(4), 663–680.
co-author countries:
United States of America 🇺🇸
author keywords: Neoplastic transformation; Tumorigenicity; Canine chromosomes; Comparative genomic hybridization (CGH); Fluorescence in situ hybridization (FISH); Madin-Darby canine kidney (MDCK) cell line; CKB1-3T7 cell line
MeSH headings : Animals; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic / genetics; Cells, Cultured; Chromosome Aberrations; DNA Copy Number Variations; Dogs; In Situ Hybridization, Fluorescence; Karyotype; Madin Darby Canine Kidney Cells; Male; Neoplasms / genetics; Neoplasms / pathology
Source: Web Of Science
Added: August 6, 2018
2015 journal article
BRAF Mutations in Canine Cancers
PLOS ONE, 10(6).
co-author countries:
United States of America 🇺🇸
Contributors: H. Mochizuki n , K. Kennedy n, S. Shapiro n & n
MeSH headings : Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Dogs; Exons / genetics; Female; Genetic Predisposition to Disease; Humans; Male; Molecular Sequence Data; Mutation / genetics; Neoplasms / genetics; Neoplasms / veterinary; Proto-Oncogene Proteins B-raf / chemistry; Proto-Oncogene Proteins B-raf / genetics; Sequence Analysis, DNA
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Canine urothelial carcinoma: genomically aberrant and comparatively relevant
Chromosome Research, 23(2), 311–331.
co-author countries:
United States of America 🇺🇸
author keywords: Canine; Urothelial carcinoma; Transitional cell carcinoma; Cytogenetics; Chromosome aberration; Array comparative genomic hybridization; Comparative oncology
MeSH headings : Animals; Biopsy; Carcinoma / veterinary; Chromosome Aberrations; Comparative Genomic Hybridization; Computational Biology / methods; DNA Copy Number Variations; Dogs; Female; Genetic Loci; Genomics / methods; Humans; In Situ Hybridization, Fluorescence; Male; Urologic Neoplasms / veterinary
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 journal article
Comparative cytogenetic characterization of primary canine melanocytic lesions using array CGH and fluorescence in situ hybridization
CHROMOSOME RESEARCH, 23(2), 171–186.
co-author countries:
United States of America 🇺🇸
author keywords: Canine; Oral melanoma; Cytogenetics; Array; Comparative genomic hybridization
MeSH headings : Animals; Chromosome Aberrations; Cluster Analysis; Comparative Genomic Hybridization; Computational Biology; DNA Copy Number Variations; Dogs; Female; Humans; In Situ Hybridization, Fluorescence; Male; Melanoma / genetics; Melanoma / metabolism; Melanoma / pathology; Mouth Neoplasms / genetics; Mouth Neoplasms / pathology; Penetrance; Skin Neoplasms
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 review
Comparative oncology: what dogs and other species can teach us about humans with cancer
co-author countries:
United States of America 🇺🇸
author keywords: comparative oncology; genomics; genetics; cancer; canine; human
MeSH headings : Animals; Breeding; Disease Models, Animal; Dog Diseases / etiology; Dogs; Female; Genome-Wide Association Study / veterinary; Genomics; Germ-Line Mutation; Humans; Male; Neoplasms / etiology; Neoplasms / veterinary; Risk Factors; Species Specificity; Translational Research, Biomedical
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Detection of BRAF Mutation in Urine DNA as a Molecular Diagnostic for Canine Urothelial and Prostatic Carcinoma
PLOS ONE, 10(12).
co-author countries:
United States of America 🇺🇸
Contributors: H. Mochizuki n , S. Shapiro n & n
MeSH headings : Animals; Biomarkers, Tumor / urine; DNA / urine; Dogs; Male; Mutation; Polymerase Chain Reaction; Prostatic Neoplasms / diagnosis; Prostatic Neoplasms / urine; Proto-Oncogene Proteins B-raf / genetics; Urinary Bladder Neoplasms / diagnosis; Urinary Bladder Neoplasms / urine
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation
Chromosome Research, 23(4), 681–708.
co-author countries:
Canada 🇨🇦 United States of America 🇺🇸
author keywords: Leukemia; Canine; Chromosome; Comparative genomic hybridization; Comparative genomics
MeSH headings : Algorithms; Animals; Cell Transformation, Neoplastic / genetics; Chromosome Aberrations; Chromosome Mapping; Cluster Analysis; Comparative Genomic Hybridization; Conserved Sequence; DNA Copy Number Variations; Disease Models, Animal; Dogs; Evolution, Molecular; Female; Gene Dosage; Genome-Wide Association Study; Genomic Library; Genomics; Humans; In Situ Hybridization, Fluorescence; Leukemia / diagnosis; Leukemia / genetics; Leukemia / metabolism; Male
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 article
Peto's paradox and the promise of comparative oncology
Nunney, L., Maley, C. C., Breen, M., Hochberg, M. E., & Schiffman, J. D. (2015, July 19). PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol. 370.
co-author countries:
France 🇫🇷 United States of America 🇺🇸
author keywords: Peto's paradox; comparative oncology; evolution; life-history theory; cancer; modelling
MeSH headings : Animals; Biological Evolution; Body Size; Cocarcinogenesis; Female; Humans; Longevity; Male; Mammals; Models, Biological; Neoplasms / etiology
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Canine Prostate Cancer Cell Line (Probasco) Produces Osteoblastic Metastases In Vivo
PROSTATE, 74(13), 1251–1265.
co-author countries:
United States of America 🇺🇸
author keywords: prostate cancer; osteoblastic metastases; canine; dog
MeSH headings : Animals; Biomarkers, Tumor / genetics; Biomarkers, Tumor / metabolism; Bone Neoplasms / genetics; Bone Neoplasms / metabolism; Bone Neoplasms / secondary; Carcinoma / genetics; Carcinoma / metabolism; Carcinoma / secondary; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dogs; Male; Mice; Mice, Nude; Neoplasm Transplantation; Osteoblasts / metabolism; Osteoblasts / pathology; Prostatic Neoplasms / genetics; Prostatic Neoplasms / metabolism; Prostatic Neoplasms / pathology
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Definition of the Cattle Killer Cell Ig-like Receptor Gene Family: Comparison with Aurochs and Human Counterparts
JOURNAL OF IMMUNOLOGY, 193(12), 6016–6030.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 Ireland 🇮🇪 United States of America 🇺🇸
MeSH headings : Animals; Cattle; Chromosome Mapping; Chromosomes, Mammalian; Cloning, Molecular; Evolution, Molecular; Gene Library; Genetic Loci; Genome; Haplotypes; Humans; Immunoglobulins / genetics; Molecular Sequence Data; Multigene Family; Phenotype; Phylogeny; Receptors, IgG / metabolism; Receptors, KIR / classification; Receptors, KIR / genetics; Receptors, KIR / metabolism; Receptors, Natural Killer Cell / metabolism; Sequence Analysis, DNA; Signal Transduction; Telomere
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma
CHROMOSOME RESEARCH, 22(3), 305–319.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
author keywords: canine; chromosome; hemangiosarcoma; comparative genomic hybridization (CGH)
MeSH headings : Animals; Breeding; Comparative Genomic Hybridization; DNA Copy Number Variations / genetics; Dog Diseases / genetics; Dogs; Gene Amplification; Gene Expression Profiling; Genetic Heterogeneity; Genome; Hemangiosarcoma / genetics; Hemangiosarcoma / veterinary; Penetrance; Vascular Endothelial Growth Factor A / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Identification of Three Molecular and Functional Subtypes in Canine Hemangiosarcoma through Gene Expression Profiling and Progenitor Cell Characterization
AMERICAN JOURNAL OF PATHOLOGY, 184(4), 985–995.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
MeSH headings : Animals; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Gene Expression Profiling; Hemangiosarcoma / genetics; Hemangiosarcoma / pathology; Hemangiosarcoma / veterinary; Immunophenotyping; Neoplastic Stem Cells / pathology; Oligonucleotide Array Sequence Analysis
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Gene selection and cancer type classification of diffuse large-B-cell lymphoma using a bivariate mixture model for two-species data
Human Genomics, 7.
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
Growth Requirements and Chromosomal Instability of Induced Pluripotent Stem Cells Generated from Adult Canine Fibroblasts
Stem Cells and Development, 22(6), 951–963.
co-author countries:
United States of America 🇺🇸
MeSH headings : Alkaline Phosphatase / metabolism; Animals; Antigens, Differentiation / genetics; Antigens, Differentiation / metabolism; Cell Differentiation; Cell Shape; Cells, Cultured; Chromosomal Instability; Coculture Techniques; Comparative Genomic Hybridization; Dogs; Fibroblasts / physiology; Gene Expression; In Situ Hybridization, Fluorescence; Induced Pluripotent Stem Cells / enzymology; Induced Pluripotent Stem Cells / pathology; Induced Pluripotent Stem Cells / transplantation; Kruppel-Like Factor 4; Mice; Mice, SCID; Recombinant Proteins / biosynthesis; Recombinant Proteins / genetics; Teratoma / genetics; Teratoma / pathology; Transcription Factors / biosynthesis; Transcription Factors / genetics
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2013 journal article
Molecular characterization of canine BCR-ABL-positive chronic myelomonocytic leukemia before and after chemotherapy
Veterinary Clinical Pathology, 42(3), 314–322.
co-author countries:
United States of America 🇺🇸
author keywords: Chromosome; cytogenetics; hematopoietic cells; remission; vincristine
MeSH headings : Animals; Chromosomes, Human, Pair 7 / genetics; Comparative Genomic Hybridization / veterinary; Dog Diseases / drug therapy; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Fusion Proteins, bcr-abl / genetics; Humans; In Situ Hybridization, Fluorescence / veterinary; Leukemia, Myelomonocytic, Chronic / drug therapy; Leukemia, Myelomonocytic, Chronic / genetics; Leukemia, Myelomonocytic, Chronic / pathology; Leukemia, Myelomonocytic, Chronic / veterinary; Male; Trisomy / genetics
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2013 article
Naturally occuring canine cancers: powerful models for stimulating pharmacogenomic advancement in human medicine
Rotroff, D. M., Thomas, R., Breen, M., & Motsinger-Reif, A. A. (2013, December). PHARMACOGENOMICS, Vol. 14, pp. 1929–1931.
co-author countries:
United States of America 🇺🇸
author keywords: cancer; canine model; chemotherapy; clinical trials
MeSH headings : Animals; Disease Models, Animal; Dogs; Humans; Neoplasms / drug therapy; Neoplasms / pathology; Pharmacogenetics / methods
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Partial cytogenetic response with toceranib and prednisone treatment in a young dog with chronic monocytic leukemia
ANTI-CANCER DRUGS, 24(10), 1098–1103.
co-author countries:
United States of America 🇺🇸
author keywords: cytogenetic analysis; fluorescence in-situ hybridization; monocytosis; toceranib; tyrosine kinase inhibitor
MeSH headings : Animals; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Cell Proliferation / drug effects; Dog Diseases / drug therapy; Dog Diseases / genetics; Dogs; Female; Fusion Proteins, bcr-abl / antagonists & inhibitors; Fusion Proteins, bcr-abl / genetics; In Situ Hybridization, Fluorescence; Indoles / administration & dosage; Indoles / therapeutic use; Leukemia, Myeloid / drug therapy; Leukemia, Myeloid / genetics; Leukemia, Myeloid / pathology; Leukemia, Myeloid / veterinary; Prednisone / administration & dosage; Prednisone / therapeutic use; Pyrroles / administration & dosage; Pyrroles / therapeutic use; Translocation, Genetic; Treatment Outcome
Source: Web Of Science
Added: August 6, 2018
2012 journal article
A genome-wide approach to comparative oncology: high-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations
Cancer Genetics, 205(11), 572–587.
co-author countries:
United States of America 🇺🇸
author keywords: Osteosarcoma; oligo-aCGH; canine; comparative oncology
MeSH headings : Adolescent; Adult; Algorithms; Animals; Bone Neoplasms / genetics; Bone Neoplasms / veterinary; Child; Chromosome Aberrations; Comparative Genomic Hybridization / methods; DNA Copy Number Variations; Dog Diseases / genetics; Dogs; Female; Genome, Human; Genomics / methods; Humans; Male; Osteosarcoma / genetics; Osteosarcoma / veterinary; Species Specificity
Source: Crossref
Added: August 14, 2021
2012 journal article
Acute myeloblastic leukemia with associated BCR-ABL translocation in a dog
VETERINARY CLINICAL PATHOLOGY, 41(3), 362–368.
co-author countries:
United States of America 🇺🇸
author keywords: Cytogenetics; FISH; immunophenotyping; Raleigh chromosome
MeSH headings : Animals; Bone Marrow / pathology; Cytogenetic Analysis / veterinary; Dog Diseases / genetics; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Fusion Proteins, bcr-abl / genetics; Hematologic Tests / veterinary; Immunophenotyping / veterinary; In Situ Hybridization, Fluorescence / veterinary; Leukemia, Myeloid, Acute / genetics; Leukemia, Myeloid, Acute / immunology; Leukemia, Myeloid, Acute / pathology; Leukemia, Myeloid, Acute / veterinary; Male; Translocation, Genetic / genetics
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Alterations of the p53 and PIK3CA/AKT/mTOR pathways in angiosarcomas
Cancer, 118(23), 5878–5887.
co-author countries:
France 🇫🇷 United States of America 🇺🇸
author keywords: angiosarcoma; p53; phosphoinositide-3-kinase; catalytic; alpha polypeptide; phosphatase and tensin homolog; complex karyotype
MeSH headings : Adult; Aged; Aged, 80 and over; Class I Phosphatidylinositol 3-Kinases; Female; Genes, p53; Genomics; Hemangiosarcoma / etiology; Hemangiosarcoma / genetics; Humans; Male; Middle Aged; Mutation; PTEN Phosphohydrolase / genetics; Phosphatidylinositol 3-Kinases / physiology; Proto-Oncogene Proteins B-raf / genetics; Proto-Oncogene Proteins c-akt / physiology; Proto-Oncogene Proteins c-mdm2 / analysis; Signal Transduction / physiology; TOR Serine-Threonine Kinases / physiology
Source: Crossref
Added: June 6, 2020
2012 journal article
Array-based comparative genomic hybridization-guided identification of reference genes for normalization of real-time quantitative polymerase chain reaction assay data for lymphomas, histiocytic sarcomas, and osteosarcomas of dogs
AMERICAN JOURNAL OF VETERINARY RESEARCH, 73(9), 1335–1343.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Comparative Genomic Hybridization / methods; Comparative Genomic Hybridization / standards; Comparative Genomic Hybridization / veterinary; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Gene Dosage; Histiocytic Sarcoma / genetics; Histiocytic Sarcoma / pathology; Histiocytic Sarcoma / veterinary; Immunohistochemistry; Lymphoma / genetics; Lymphoma / pathology; Lymphoma / veterinary; Osteosarcoma / genetics; Osteosarcoma / pathology; Osteosarcoma / veterinary; RNA, Neoplasm / chemistry; RNA, Neoplasm / genetics; Real-Time Polymerase Chain Reaction / methods; Real-Time Polymerase Chain Reaction / standards; Real-Time Polymerase Chain Reaction / veterinary; Reference Standards
Source: Web Of Science
Added: August 6, 2018
2012 journal article
CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies
LEUKEMIA & LYMPHOMA, 53(7), 1390–1398.
co-author countries:
United States of America 🇺🇸
author keywords: Diffuse large B-cell lymphoma; CD40L; primary cell culture; canine model; cytotoxicity assay
MeSH headings : Animals; CD40 Ligand / genetics; CD40 Ligand / metabolism; CD40 Ligand / pharmacology; Cell Culture Techniques / methods; Cell Proliferation / drug effects; Cell Survival / drug effects; Coculture Techniques; Dogs; Dose-Response Relationship, Drug; Feeder Cells / metabolism; Gene Expression Profiling; Humans; Lymphoma, Large B-Cell, Diffuse / genetics; Lymphoma, Large B-Cell, Diffuse / metabolism; Lymphoma, Large B-Cell, Diffuse / pathology; Oligonucleotide Array Sequence Analysis; Recombinant Proteins / pharmacology; Tumor Cells, Cultured
Source: Web Of Science
Added: August 6, 2018
2012 conference paper
Generation and characterization of induced pluripotent stem cells (iPS) from adult canine fibroblasts
Reproduction in Domestic Animals, 47, 418–419.
Source: NC State University Libraries
Added: August 6, 2018
2012 journal article
Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma
BONE, 50(1), 171–181.
co-author countries:
United States of America 🇺🇸
author keywords: Bone neoplasm; cMYC; Osteosarcoma; miR-17-92; 14q32 miRNAs
MeSH headings : Adolescent; Bone Neoplasms / genetics; Bone Neoplasms / pathology; Bone and Bones / anatomy & histology; Bone and Bones / pathology; Bone and Bones / physiology; Cell Line, Tumor; Child; Chromosomes, Human, Pair 14 / genetics; DNA Copy Number Variations; Gene Expression Profiling; Gene Regulatory Networks; Humans; MicroRNAs / genetics; Microarray Analysis; Multigene Family; Osteosarcoma / genetics; Osteosarcoma / pathology; Proto-Oncogene Proteins c-myc / genetics
Source: Web Of Science
Added: August 6, 2018
2012 journal article
The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification
GENES CHROMOSOMES & CANCER, 51(6), 569–578.
co-author countries:
United States of America 🇺🇸
MeSH headings : Adult; Aged; Aged, 80 and over; Comparative Genomic Hybridization; DNA-Binding Proteins / biosynthesis; DNA-Binding Proteins / genetics; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Genes, myc; Hemangiosarcoma / chemistry; Hemangiosarcoma / genetics; Hemangiosarcoma / metabolism; Humans; In Situ Hybridization, Fluorescence; Male; MicroRNAs / biosynthesis; MicroRNAs / genetics; Middle Aged; Proto-Oncogene Proteins c-myc / biosynthesis; Proto-Oncogene Proteins c-myc / genetics; RNA, Long Noncoding; Sequence Analysis, RNA; Thrombospondin 1 / biosynthesis; Thrombospondin 1 / genetics; Transcription Factors / biosynthesis; Transcription Factors / genetics; Vascular Neoplasms / chemistry; Vascular Neoplasms / genetics; Vascular Neoplasms / metabolism
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Anchoring the dog to its relatives reveals new evolutionary breakpoints across 11 species of the Canidae and provides new clues for the role of B chromosomes
CHROMOSOME RESEARCH, 19(6), 685–708.
co-author countries:
Russian Federation 🇷🇺 United States of America 🇺🇸
author keywords: B chromosomes; fragile breakage model; breakpoint reuse theory; fluorescence in situ hybridization; phylogenetic; Canidae
MeSH headings : Animals; Biological Evolution; Canidae / genetics; Chromosome Mapping; Chromosome Painting; Chromosomes, Artificial, Bacterial; Chromosomes, Mammalian / genetics; Cytogenetics; Dogs / genetics; Foxes / genetics; Genome; In Situ Hybridization, Fluorescence; Raccoon Dogs / genetics
Source: Web Of Science
Added: August 6, 2018
2011 journal article
BCR-ABL translocation in a dog with chronic monocytic leukemia
VETERINARY CLINICAL PATHOLOGY, 40(1), 40–47.
co-author countries:
United States of America 🇺🇸
author keywords: FISH; flow cytometry; monocytosis; myeloproliferative disorder
MeSH headings : Animals; Bone Marrow Cells / pathology; Dog Diseases / diagnosis; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Flow Cytometry / veterinary; Leukemia, Myeloid / diagnosis; Leukemia, Myeloid / genetics; Leukemia, Myeloid / pathology; Leukemia, Myeloid / veterinary; Translocation, Genetic / genetics
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Characterization of Canine Osteosarcoma by Array Comparative Genomic Hybridization and RT-qPCR: Signatures of Genomic Imbalance in Canine Osteosarcoma Parallel the Human Counterpart
GENES CHROMOSOMES & CANCER, 50(11), 859–874.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Bone Neoplasms / genetics; Bone Neoplasms / veterinary; Comparative Genomic Hybridization; Core Binding Factor Alpha 1 Subunit / genetics; DNA Copy Number Variations; Dog Diseases / genetics; Dogs; Female; Gene Dosage; Genomic Instability; Humans; In Situ Hybridization, Fluorescence; Male; Membrane Proteins / genetics; Osteosarcoma / genetics; Osteosarcoma / veterinary; PTEN Phosphohydrolase / genetics; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Tumor Suppressor Proteins / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
Development of a Brain Metastatic Canine Prostate Cancer Cell Line
PROSTATE, 71(12), 1251–1263.
co-author countries:
United States of America 🇺🇸
author keywords: prostate cancer; brain metastasis; spinal cord metastasis; dog; canine; bone metastasis
MeSH headings : Adrenal Gland Neoplasms / epidemiology; Adrenal Gland Neoplasms / secondary; Animals; Antineoplastic Agents / pharmacology; Bone Neoplasms / epidemiology; Bone Neoplasms / secondary; Boronic Acids / pharmacology; Bortezomib; Brain Neoplasms / epidemiology; Brain Neoplasms / metabolism; Brain Neoplasms / pathology; Brain Neoplasms / secondary; Carcinogenicity Tests; Carcinoma / epidemiology; Carcinoma / metabolism; Carcinoma / pathology; Carcinoma / secondary; Cell Division; Cell Line, Tumor / drug effects; Cell Line, Tumor / pathology; Dogs; Immunohistochemistry; Incidence; Injections, Subcutaneous; Keratin-18 / metabolism; Keratin-7 / metabolism; Keratin-8 / metabolism; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Connective Tissue / secondary; Parathyroid Hormone-Related Protein / metabolism; Phenylbutyrates / antagonists & inhibitors; Prostatic Neoplasms / pathology; Pyrazines / pharmacology; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord Neoplasms / epidemiology; Spinal Cord Neoplasms / secondary; Subcutaneous Tissue; Transplantation, Heterologous
Source: Web Of Science
Added: August 6, 2018
2011 journal article
FLT3 mutations in canine acute lymphocytic leukemia
BMC CANCER, 11.
co-author countries:
United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Animals; Blotting, Western; Carbazoles / pharmacology; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Survival / drug effects; DNA Mutational Analysis; DNA, Neoplasm / chemistry; DNA, Neoplasm / genetics; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases / metabolism; Furans; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Mutation; Phosphorylation / drug effects; Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma / metabolism; Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology; Reverse Transcriptase Polymerase Chain Reaction; STAT5 Transcription Factor / metabolism; fms-Like Tyrosine Kinase 3 / antagonists & inhibitors; fms-Like Tyrosine Kinase 3 / genetics; fms-Like Tyrosine Kinase 3 / metabolism
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach
BONE, 49(3), 356–367.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
author keywords: Osteosarcoma; Gene expression profiling; Cell cycle; DNA damage checkpoint; Tumor microenvironment; Canine
MeSH headings : Animals; Bone Neoplasms / classification; Bone Neoplasms / genetics; Bone Neoplasms / pathology; Cluster Analysis; Cohort Studies; Cyclin B2 / genetics; Cyclin B2 / metabolism; Dogs; Female; Gene Expression Profiling; Humans; Kaplan-Meier Estimate; Male; Oligonucleotide Array Sequence Analysis / methods; Osteosarcoma / classification; Osteosarcoma / genetics; Osteosarcoma / pathology; Prognosis; Vimentin / genetics; Vimentin / metabolism
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Reading between the lines: molecular characterization of five widely used canine lymphoid tumour cell lines
Veterinary and Comparative Oncology, 11(1), 30–50.
co-author countries:
United States of America 🇺🇸
author keywords: canine; cell line; comparative; lymphoid neoplasia; microarray; model
MeSH headings : Animals; Cell Line, Tumor; DNA / genetics; DNA / metabolism; Dog Diseases / metabolism; Dogs; Flow Cytometry; Gene Expression Regulation, Neoplastic / physiology; Karyotype; Lymphoma / metabolism; Neoplasm Proteins / genetics; Neoplasm Proteins / metabolism; RNA / genetics; RNA / metabolism; Real-Time Polymerase Chain Reaction / veterinary; Transcriptome
Sources: Web Of Science, Crossref
Added: August 6, 2018
2011 journal article
Refining tumor-associated aneuploidy through ‘genomic recoding’ of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas
Leukemia & Lymphoma, 52(7), 1321–1335.
author keywords: Comparative genomic hybridization (CGH); canine; lymphoma; chromosome; microarray
MeSH headings : Aneuploidy; Animals; Breeding; Comparative Genomic Hybridization; Cyclin-Dependent Kinase Inhibitor p16 / genetics; DNA Copy Number Variations / genetics; Dogs; Gene Expression Regulation, Neoplastic; Genomics; Immunophenotyping; Lymphoma, Non-Hodgkin / genetics; Lymphoma, Non-Hodgkin / pathology
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2011 journal article
The genome of the green anole lizard and a comparative analysis with birds and mammals
Nature, 477(7366), 587–591.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 Sweden 🇸🇪 United States of America 🇺🇸
MeSH headings : Animals; Birds / genetics; Chickens / genetics; Evolution, Molecular; GC Rich Sequence / genetics; Genome / genetics; Genomics; Humans; Lizards / genetics; Mammals / genetics; Molecular Sequence Data; Phylogeny; Synteny / genetics; X Chromosome / genetics
Source: Crossref
Added: August 14, 2021
2010 journal article
Mature Hair Follicles Generated from Dissociated Cells: A Universal Mechanism of Folliculoneogenesis
DEVELOPMENTAL DYNAMICS, 239(10), 2619–2626.
co-author countries:
United States of America 🇺🇸
author keywords: hair follicle; morphogenesis; organogenesis
MeSH headings : Animals; Cell Cycle / genetics; Cell Cycle / physiology; Dogs; Hair Follicle / cytology; Hair Follicle / embryology; Humans; Opossums; Organogenesis / genetics; Organogenesis / physiology; Rats; Skin / cytology; Skin / metabolism
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Predicting Residential Air Exchange Rates from Questionnaires and Meteorology: Model Evaluation in Central North Carolina
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 44(24), 9349–9356.
co-author countries:
United States of America 🇺🇸
MeSH headings : Air Movements; Air Pollutants / analysis; Air Pollution, Indoor / analysis; Air Pollution, Indoor / statistics & numerical data; Atmosphere / chemistry; Environmental Monitoring / methods; Forecasting; Meteorological Concepts; Models, Chemical; North Carolina; Particle Size; Seasons; Surveys and Questionnaires
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Extensive conservation of genomic imbalances in canine transmissible venereal tumors (CTVT) detected by microarray-based CGH analysis
CHROMOSOME RESEARCH, 17(7), 927–934.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: comparative genomic hybridization (CGH); canine; transmissible venereal tumor; chromosome; microarray
MeSH headings : Animals; Comparative Genomic Hybridization; DNA Copy Number Variations; Dog Diseases / genetics; Dog Diseases / immunology; Dog Diseases / transmission; Dogs; Female; Gene Expression Regulation, Neoplastic; Genome; Male; Oligonucleotide Array Sequence Analysis; Venereal Tumors, Veterinary / genetics; Venereal Tumors, Veterinary / immunology
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Generation and characterization of novel canine malignant mast cell line CL1
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 127(1-2), 114–124.
co-author countries:
United States of America 🇺🇸
author keywords: Mast cell tumor; KIT; Cell line
MeSH headings : Animals; Base Sequence; Cell Degranulation; Cell Line, Tumor; DNA Primers / genetics; DNA, Neoplasm / genetics; Dog Diseases / genetics; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Female; Genome-Wide Association Study; Immunophenotyping; Mast Cells / immunology; Mast Cells / pathology; Mast Cells / physiology; Mastocytosis, Systemic / genetics; Mastocytosis, Systemic / immunology; Mastocytosis, Systemic / pathology; Mastocytosis, Systemic / veterinary; Proto-Oncogene Proteins c-kit / genetics; Proto-Oncogene Proteins c-kit / metabolism
Source: Web Of Science
Added: August 6, 2018
2009 journal article
IDH1 and IDH2 hotspot mutations are not found in canine glioma
International Journal of Cancer, 127(1), 245–246.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Brain Neoplasms / genetics; Brain Neoplasms / veterinary; Dogs; Glioma / genetics; Glioma / veterinary; Isocitrate Dehydrogenase / genetics; Isoenzymes / genetics; Mutation
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2009 journal article
Influence of genetic background on tumor karyotypes: Evidence for breed-associated cytogenetic aberrations in canine appendicular osteosarcoma
CHROMOSOME RESEARCH, 17(3), 365–377.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: microarray; comparative genomic hybridization (CGH); canine; osteosarcoma; chromosome
MeSH headings : Animals; Chromosome Aberrations / veterinary; Comparative Genomic Hybridization; Dog Diseases / genetics; Dogs; Genetic Predisposition to Disease / genetics; Karyotyping / veterinary; Osteosarcoma / genetics; Osteosarcoma / veterinary; Species Specificity
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Microarray-based cytogenetic profiling reveals recurrent and subtype-associated genomic copy number aberrations in feline sarcomas
CHROMOSOME RESEARCH, 17(8), 987–1000.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 Sweden 🇸🇪 United States of America 🇺🇸
author keywords: microarray; comparative genomic hybridization (CGH); feline; sarcoma; chromosome
MeSH headings : Animals; Cat Diseases / diagnosis; Cats; Cytogenetic Analysis; DNA Copy Number Variations; Gene Dosage; Gene Expression Profiling; Injections / adverse effects; Oligonucleotide Array Sequence Analysis; Sarcoma / diagnosis; Sarcoma / genetics; Sarcoma / veterinary
Source: Web Of Science
Added: August 6, 2018
2009 journal article
ORIGINS AND EVOLUTION OF A TRANSMISSIBLE CANCER
EVOLUTION, 63(9), 2340–2349.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: Chromosomal evolution; evolutionary genomics; genetic variation; molecular evolution; population genetics; sex
MeSH headings : Animals; Biological Evolution; Comparative Genomic Hybridization / methods; Dog Diseases / genetics; Dogs / classification; Dogs / genetics; Gene Dosage; Genotype; Microarray Analysis; Microsatellite Repeats / genetics; Neoplasms / genetics; Neoplasms / veterinary; Phylogeny; Venereal Tumors, Veterinary / genetics; Wolves / genetics
Source: Web Of Science
Added: August 6, 2018
2009 review
Update on Genomics in Veterinary Oncology
[Review of ]. TOPICS IN COMPANION ANIMAL MEDICINE, 24(3), 113–121.
co-author countries:
United States of America 🇺🇸
author keywords: cancer; genomics; oncology; technology; veterinary
MeSH headings : Animals; Cat Diseases / genetics; Cats; Dog Diseases / genetics; Dogs; Genomics / methods; Neoplasms / genetics; Neoplasms / veterinary; Veterinary Medicine / methods
Source: Web Of Science
Added: August 6, 2018
2009 journal article
‘Putting our heads together’: insights into genomic conservation between human and canine intracranial tumors
Journal of Neuro-Oncology, 94(3), 333–349.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: Comparative genomic hybridization; Canine; Brain tumor; Chromosome; Microarray
MeSH headings : Animals; Brain Neoplasms / genetics; Brain Neoplasms / pathology; Chromosome Aberrations; Chromosome Mapping; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 22; Cluster Analysis; Dogs; Female; Gene Expression Regulation, Neoplastic; Genome / genetics; Glioma / genetics; Glioma / pathology; Humans; In Situ Hybridization, Fluorescence; Male; Meningeal Neoplasms / genetics; Meningeal Neoplasms / pathology; Meningioma / genetics; Meningioma / pathology
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2008 journal article
A genome assembly-integrated dog 1 Mb BAC microarray: a cytogenetic resource for canine cancer studies and comparative genomic analysis
CYTOGENETIC AND GENOME RESEARCH, 122(2), 110–121.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
MeSH headings : Animals; Chromosomes / genetics; Comparative Genomic Hybridization; Cytogenetics; Databases, Nucleic Acid; Dogs; Genome / genetics; In Situ Hybridization, Fluorescence; Neoplasms / genetics; Oligonucleotide Array Sequence Analysis
Source: Web Of Science
Added: August 6, 2018
2008 article
Canine cytogenetics - from band to basepair
CYTOGENETIC AND GENOME RESEARCH, Vol. 120, pp. 50–60.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Base Pairing; Chromosome Banding / veterinary; Chromosome Mapping / veterinary; Chromosome Painting / veterinary; Cytogenetic Analysis / standards; Cytogenetic Analysis / veterinary; Cytogenetics; Dog Diseases / genetics; Dogs / genetics; Evolution, Molecular; Female; In Situ Hybridization, Fluorescence / veterinary; Karyotyping / veterinary; Male; Neoplasms / genetics; Neoplasms / veterinary; Nucleic Acid Hybridization
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Enhancement of extra chromosomal recombination in somatic cells by affecting the ratio of homologous recombination (HR) to non-homologous end joining (NHEJ)
ANIMAL BIOTECHNOLOGY, 19(1), 6–21.
co-author countries:
United States of America 🇺🇸
author keywords: extra chromosomal; homologous recombination; somatic cells
MeSH headings : Acetyltransferases / genetics; Animals; Cell Physiological Phenomena; Chromosomes / genetics; DNA Primers; DNA Repair; Plasmids; Recombination, Genetic; Swine; Tumor Suppressor Protein p53 / genetics
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Evolutionarily conserved cytogenetic changes in hematological malignancies of dogs and humans - man and his best friend share more than companionship
CHROMOSOME RESEARCH, 16(1), 145–154.
co-author countries:
United States of America 🇺🇸
author keywords: chromosome; comparative; dog; evolution; leukemia; lymphoma
MeSH headings : Animals; Chromosome Aberrations; Conserved Sequence; Cytogenetics; Dogs; Evolution, Molecular; Hematologic Neoplasms / genetics; Humans; Male; Synteny / genetics; Translocation, Genetic
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Tackling the characterization of canine chromosomal breakpoints with an integrated in-situ/in-silico approach: The canine PAR and PAB
CHROMOSOME RESEARCH, 16(8), 1193–1202.
co-author countries:
United States of America 🇺🇸
author keywords: Canis familiaris; chromosomal breakpoints; dog; PAR; PAB
MeSH headings : Animals; Chromosome Breakage; Chromosome Mapping / methods; Chromosomes, Artificial, Bacterial; Chromosomes, Mammalian / genetics; Dogs / genetics; X Chromosome / genetics
Source: Web Of Science
Added: August 6, 2018
2007 article
A cytogenetically characterized, genome-anchored 10-Mb BAC set and CGH array for the domestic dog
JOURNAL OF HEREDITY, Vol. 98, pp. 474–484.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
MeSH headings : Animals; Chromosome Mapping; Chromosomes, Artificial, Bacterial / genetics; Dogs / genetics; Genome; In Situ Hybridization, Fluorescence; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Sensitivity and Specificity
Source: Web Of Science
Added: August 6, 2018
2007 journal article
A novel canine lymphoma cell line: A translational and comparative model for lymphoma research
LEUKEMIA RESEARCH, 31(12), 1709–1720.
co-author countries:
United States of America 🇺🇸
author keywords: canine lymphoma; cell line; array comparative genomic hybridization; bioluminescent imaging; xenograft
MeSH headings : Animals; Biomedical Research; Cell Line, Tumor; Dogs; Immunophenotyping; Lymphoma / pathology; Mice; Mice, SCID; Neoplasm Transplantation; Transplantation, Heterologous
Source: Web Of Science
Added: August 6, 2018
2007 review
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
[Review of ]. NATURE, 447(7141), 167–U1.
MeSH headings : Animals; Base Composition; Conserved Sequence / genetics; DNA Transposable Elements / genetics; Evolution, Molecular; Genome / genetics; Genomics; Humans; Opossums / genetics; Polymorphism, Single Nucleotide / genetics; Protein Biosynthesis; Synteny / genetics; X Chromosome Inactivation / genetics
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Inactivation of the p16 cyclin-dependent kinase inhibitor in high-grade canine non-Hodgkin's T-Cell lymphoma
VETERINARY PATHOLOGY, 44(4), 467–478.
co-author countries:
United States of America 🇺🇸
author keywords: canines; cell cycle; non-Hodgkin's lymphoma; tumor suppressor genes
MeSH headings : Animals; Cyclin-Dependent Kinase Inhibitor p16 / genetics; Cyclin-Dependent Kinase Inhibitor p16 / metabolism; Dog Diseases / metabolism; Dogs; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Lymphoma, B-Cell / metabolism; Lymphoma, B-Cell / veterinary; Lymphoma, T-Cell / metabolism; Lymphoma, T-Cell / veterinary; Male; Retinoblastoma Protein / genetics; Retinoblastoma Protein / metabolism
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Integrated cytogenetic BAC map of the genome of the gray, short-tailed opossum, Monodelphis domestica
CHROMOSOME RESEARCH, 15(3), 361–370.
co-author countries:
United States of America 🇺🇸
author keywords: chromosome; cytogenetic; genome; map; Monodelphis
MeSH headings : Animals; Base Sequence; Chromosome Mapping / methods; Chromosomes, Artificial, Bacterial; Cytogenetics / methods; Genome / genetics; Genomics / methods; In Situ Hybridization, Fluorescence; Monodelphis / genetics
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Predictive value of p16 or Rb inactivation in a model of naturally occurring canine non-Hodgkin's lymphoma
Leukemia, 21(1), 184–187.
co-author countries:
United States of America 🇺🇸
MeSH headings : Age of Onset; Animals; Disease Models, Animal; Dog Diseases / genetics; Dog Diseases / physiopathology; Dogs; Gene Silencing; Genes, Retinoblastoma; Genes, p16; Genetic Predisposition to Disease; Lymphoma, Non-Hodgkin / genetics; Lymphoma, Non-Hodgkin / physiopathology; Lymphoma, Non-Hodgkin / veterinary; Predictive Value of Tests; Species Specificity
Source: Crossref
Added: September 18, 2021
2007 journal article
The search for a marsupial XIC reveals a break with vertebrate synteny
Chromosome Research, 15(2), 137–146.
co-author countries:
United States of America 🇺🇸
author keywords: marsupial; Monodelphis domestica; noncoding RNA; TSIX; X-chromosome; XIC; X inactivation center; XIST
MeSH headings : Animals; Chromosome Walking; Computational Biology; Cytogenetic Analysis; DNA-Binding Proteins / genetics; Evolution, Molecular; Female; Genes, X-Linked; Genomics; Humans; Male; Monocarboxylic Acid Transporters / genetics; Monodelphis / genetics; RNA, Long Noncoding; RNA, Untranslated / genetics; Symporters; Synteny; Transcription Factors / genetics; Vertebrates / genetics; X Chromosome; X Chromosome Inactivation
Sources: Crossref, Web Of Science
Added: August 6, 2018
2006 personal communication
The dog as a cancer model
Khanna, C., Lindblad-Toh, K., Vail, D., London, C., Bergman, P., Barber, L., … Withrow, S. (2006, September).
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Disease Models, Animal; Dogs; Humans; Neoplasms / physiopathology; Neoplasms / veterinary
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Genome sequence, comparative analysis and haplotype structure of the domestic dog
Nature, 438(7069), 803–819.
MeSH headings : Animals; Conserved Sequence / genetics; Dog Diseases / genetics; Dogs / classification; Dogs / genetics; Evolution, Molecular; Female; Genome / genetics; Genomics; Haplotypes / genetics; Humans; Hybridization, Genetic; Male; Mice; Mutagenesis / genetics; Polymorphism, Single Nucleotide / genetics; Rats; Short Interspersed Nucleotide Elements / genetics; Synteny / genetics
Sources: Crossref, Web Of Science
Added: August 6, 2018
2004 journal article
A high-resolution comparative map of canine Chromosome 5q14.3–q33 constructed utilizing the 1.5× canine genomesequence
Mammalian Genome, 15(7), 544–551.
co-author countries:
France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Norway 🇳🇴 United States of America 🇺🇸
MeSH headings : Animals; Chromosome Mapping; Chromosomes / ultrastructure; Chromosomes, Artificial, Bacterial; Crosses, Genetic; DNA / metabolism; DNA Primers / chemistry; Dogs; Gene Library; Genetic Linkage; Genetic Predisposition to Disease; Genome; Genome, Human; Genotype; Humans; Microsatellite Repeats; Models, Genetic; Polymorphism, Single Nucleotide; Species Specificity
Sources: Crossref, Web Of Science
Added: August 6, 2018
2004 journal article
Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium
Laboratory Investigation, 84(5), 562–572.
co-author countries:
United States of America 🇺🇸
author keywords: canine; endothelial cells; angiosarcoma; angiogenesis; CD117; NFAT; nicotine
MeSH headings : Animals; Antigens, CD / metabolism; Cell Adhesion; Cell Division; Cell Line, Tumor; Cell Movement; DNA, Neoplasm / analysis; DNA, Neoplasm / genetics; Dog Diseases / pathology; Dog Diseases / physiopathology; Dogs; Endothelium, Vascular / pathology; Hemangiosarcoma / blood supply; Hemangiosarcoma / pathology; Hemangiosarcoma / physiopathology; Hemangiosarcoma / veterinary; Humans; Models, Biological; Neovascularization, Pathologic; Ploidies; Vascular Endothelial Growth Factor A / metabolism
Sources: Crossref, Web Of Science
Added: August 6, 2018
journal article
A comprehensive genomic history of extinct and living elephants
Palkopoulou, E., Lipson, M., Mallick, S., Nielsen, S., Rohland, N., Baleka, S., … Meller, H. Proceedings of the National Academy of Sciences of the United States of America, 115(11), E2566–2574.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Creation of an NCI comparative brain tumor consortium: informing the translation of new knowledge from canine to human brain tumor patients
LeBlanc, A. K., Mazcko, C., Brown, D. E., Koehler, J. W., Miller, A. D., Miller, C. R., … Dickinson, P. J. Neuro-Oncology, 18(9), 1209–1218.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Cytogenetic BAC map of the genome of Monodelphis domestica
Duke, S. E., Samallow, P., Mauceli, E., Lindblad-Toh, K., & Breen, M. Chromosome Research, 15, 3610–3670.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background
Elvers, I., Turner-Maier, J., Swofford, R., Koltookian, M., Johnson, J., Stewart, C., … Lindblad-Toh, K. Genome Research, 25(11), 1634–1645.
Source: NC State University Libraries
Added: August 6, 2018
review
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
Mikkelsen, T. S., Wakefield, M. J., Aken, B., Amemiya, C. T., Chang, J. L., Duke, S., … al. [Review of ]. 254, 447(7141), 167–161.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B
Karlsson, E. K., Sigurdsson, S., Ivansson, E., Thomas, R., Elvers, I., Wright, J., … Rivera, P. Genome Biology, 14(12).
Source: NC State University Libraries
Added: August 6, 2018
journal article
Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers
Tonomura, N., Elvers, I., Thomas, R., Megquier, K., Turner-Maier, J., Howald, C., … Kim, J. H. PLoS Genetics, 11(2).
Source: NC State University Libraries
Added: August 6, 2018
journal article
Molecular profiling reveals prognostically significant subtypes of canine lymphoma
Frantz, A. M., Sarver, A. L., Ito, D., Phang, T. L., Karimpour-Fard, A., Scott, M. C., … O'Brien, T. D. Veterinary Pathology, 50(4), 693–703.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Naturally occurring translational models for development of cancer gene therapy
Modiano, J. F., Breen, M., Lana, S. E., Ehrhart, N., Fosmire, S. P., Thomas, R., … Bellgrau, D. Gene Therapy & Molecular Biology, 10A, 31–40.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology
LeBlanc, A. K., Breen, M., Choyke, P., Dewhirst, M., Fan, T. M., Gustafson, D. L., … Trent, J. M. Science Translational Medicine, 8(324).
Source: NC State University Libraries
Added: August 6, 2018
personal communication
Predictive value of p16 or Rb inactivation in a model of naturally occurring canine non-Hodgkin's lymphoma
Modiano, J. F., Breen, M., O Valli, V. E., Wojcieszyn, J. W., & Cutter, G. R.
Source: NC State University Libraries
Added: August 6, 2018
journal article
SETD2 is recurrently mutated in whole-exome sequenced canine osteosarcoma
Sakthikumar, S., Elvers, I., Kim, J., Arendt, M. L., Thomas, R., Turner-Maier, J., … Modiano, J. F. Cancer Research, 78(13), 3421–3431.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Safe and effective sarcoma therapy through bispecific targeting of EGFR and uPAR
Borgatti, A., Koopmeiners, J. S., Sarver, A. L., Winter, A. L., Stuebner, K., Todhunter, D., … Oh, F. Molecular Cancer Therapeutics, 16(5), 956–965.
Source: NC State University Libraries
Added: August 6, 2018
journal article
The MTAP-CDKN2A locus confers susceptibility to a naturally occurring canine cancer
Shearin, A. L., Hedan, B., Cadieu, E., Erich, S. A., Schmidt, E. V., Faden, D. L., … Andre, C. Cancer Epidemiology Biomarkers, 21(7), 1019–1027.
Source: NC State University Libraries
Added: August 6, 2018
journal article
The genome of the green anole lizard and a comparative analysis with birds and mammals
Alfoldi, J., Di Palma, F., Grabherr, M., Williams, C., Kong, L. S., Mauceli, E., … Moreno, R. G. Nature, 477(7366), 587–591.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs
Green, R. E., Braun, E. L., Armstrong, J., Earl, D., Nguyen, N., Hickey, G., … Hubley, R. M. Science, 346(6215), 1335-.
Source: NC State University Libraries
Added: August 6, 2018
