Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution
Schaaf, G., Dynowski, M., Mousley, C. J., Shah, S. D., Yuan, P., Winklbauer, E. M., … Bankaitis, V. A. (2011, January 20). Molecular Biology of the Cell, Vol. 22, pp. 892–905.
topics (OpenAlex): Cellular transport and secretion; Protein Structure and Dynamics; CRISPR and Genetic Engineering
TL;DR:
A directed evolution approach is used as a novel prism through which the functional engineering of a Sec14-like phosphatidylinositol transfer protein can be observed.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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