@article{mccain_dalman_berno_libera_lewek_sawicki_saul_2023, title={The influence of induced gait asymmetry on joint reaction forces}, volume={153}, ISSN={["1873-2380"]}, DOI={10.1016/j.jbiomech.2023.111581}, abstractNote={Chronic injury- or disease-induced joint impairments result in asymmetric gait deviations that may precipitate changes in joint loading associated with pain and osteoarthritis. Understanding the impact of gait deviations on joint reaction forces (JRFs) is challenging because of concurrent neurological and/or anatomical changes and because measuring JRFs requires medically invasive instrumented implants. Instead, we investigated the impact of joint motion limitations and induced asymmetry on JRFs by simulating data recorded as 8 unimpaired participants walked with bracing to unilaterally and bilaterally restrict ankle, knee, and simultaneous ankle + knee motion. Personalized models, calculated kinematics, and ground reaction forces (GRFs) were input into a computed muscle control tool to determine lower limb JRFs and simulated muscle activations guided by electromyography-driven timing constraints. Unilateral knee restriction increased GRF peak and loading rate ipsilaterally but peak values decreased contralaterally when compared to walking without joint restriction. GRF peak and loading rate increased with bilateral restriction compared to the contralateral limb of unilaterally restricted conditions. Despite changes in GRFs, JRFs were relatively unchanged due to reduced muscle forces during loading response. Thus, while joint restriction results in increased limb loading, reductions in muscle forces counteract changes in limb loading such that JRFs were relatively unchanged.}, journal={JOURNAL OF BIOMECHANICS}, author={McCain, Emily M. and Dalman, Morgan J. and Berno, Matthew E. and Libera, Theresa L. and Lewek, Michael D. and Sawicki, Gregory S. and Saul, Katherine R.}, year={2023}, month={May} } @article{dalman_liao_saul_2022, title={Evaluating anthropometric scaling of a generic adult model to represent pediatric shoulder strength}, volume={141}, ISSN={["1873-2380"]}, DOI={10.1016/j.jbiomech.2022.111170}, abstractNote={The structure of the developing musculoskeletal system during childhood and adolescence influences tissue loading and function. Anatomical features important for musculoskeletal loading such as muscle volume and limb proportion vary with age but limited available anatomical data for the developing limb makes predicting loads challenging. Our aim was to evaluate whether anthropometric scaling of an existing adult musculoskeletal upper limb model is sufficient to accurately represent pediatric strength. An adult upper limb model was scaled using two scale factors based on length features and max isometric force (MIF). Length features (e.g. limb and muscle length) were scaled based on linear regression for available literature reports of forearm length vs. height (N = 366 Pediatric, N = 107 Adults), while MIF was scaled based on relating body mass vs. total shoulder muscle volume (N = 6). Children-specific models were developed for 6 pediatric individuals whose height, body mass, and shoulder moment-generating capacity (a common measure of strength) were previously reported. These models were used to predict isometric shoulder moments for flexion/extension, internal/external rotation, and ad/abduction and compared with physical measurements previously reported. The predicted isometric shoulder moments were significantly correlated to measured moments for these same individuals (p < 0.04, r2 > 0.7). However, predicted moments tended to underestimate measured values; shoulder external rotation was most accurately predicted (slope: 1.1234) while shoulder adduction was most underestimated (slope: 0.4624). This work provides an initial basis for pediatric scaling but illustrates the important need for additional direct measures of muscle size and limb strength and function in a pediatric population.}, journal={JOURNAL OF BIOMECHANICS}, author={Dalman, Morgan and Liao, Ashlee and Saul, Katherine R.}, year={2022}, month={Aug} }