Matt Koci
Also known as: Matt Koci
Works (63)
Updated: December 12th, 2024 05:08
2024 journal article
Fluoroquinolone-resistant Campylobacter in backyard and commercial broiler production systems in the United States
JAC-ANTIMICROBIAL RESISTANCE, 6(4).
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 22, 2024
2024 journal article
Pleurotus eryngii polysaccharides alleviate aflatoxin B 1-induced liver inflammation in ducks involving in remodeling gut microbiota and regulating SCFAs transport via the gut-liver axis
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 271.
author keywords: Aflatoxin B 1; Pleurotus eryngii polysaccharides; Gut -liver axis
Sources: Web Of Science, NC State University Libraries
Added: June 24, 2024
2024 journal article
Rutin, a natural flavonoid glycoside, ameliorates zearalenone induced liver inflammation via inhibiting lipopolysaccharide gut leakage and NF-κB signaling pathway in mice
FOOD AND CHEMICAL TOXICOLOGY, 191.
author keywords: Zearalenone; Flavonoids; Rutin; Human health; Inflammation
Sources: Web Of Science, NC State University Libraries
Added: August 14, 2024
2024 journal article
Widespread prevalence of plasmid-mediated <i>bla</i><sub>CTX-M</sub> type extended-spectrum beta-lactamase <i>Escherichia coli</i> in backyard broiler production systems in the United States
PLOS ONE, 19(6).
Ed(s): G. Trueba
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 8, 2024
2023 article
Beyond Better Medicines
Koci, M. (2023, August 4).
Source: ORCID
Added: January 28, 2024
2023 journal article
Chlorogenic Acid Alleviated AFB1-Induced Hepatotoxicity by Regulating Mitochondrial Function, Activating Nrf2/HO-1, and Inhibiting Noncanonical NF-κB Signaling Pathway
ANTIOXIDANTS, 12(12).
author keywords: chlorogenic acid; aflatoxin B1; hepatotoxicity; antioxidant; anti-inflammatory; mitochondrial function
TL;DR:
Findings revealed a possible mechanism: CGA prevents AFB1-induced cytotoxicity by maintaining mitochondrial membrane potential, activating Nrf2/HO-1, and inhibiting the noncanonical NF-κB signaling pathway, which may provide a new direction for the application of CGA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: January 8, 2024
2023 journal article
NF-KB activation enhances STING signaling by altering microtubule-mediated STING trafficking
CELL REPORTS, 42(3).
MeSH headings : Interferons; NF-kappa B / metabolism; Signal Transduction / genetics; Toll-Like Receptors; Membrane Proteins
TL;DR:
It is demonstrated that NF-κB activation enhances STING signaling by regulating microtubule-mediated STING trafficking and triggering a cascade-amplified interferon response and robust host antiviral defense.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 4, 2023
2023 article
Science Communication Training Imparts Confidence and Influences Public Engagement Activity
Swords, C. M., Porter, J. S., Hawkins, A. J., Li, E., Rowland-Goldsmith, M., Koci, M. D., … Woitowich, N. C. (2023, July 17). (L. Brancaccio-Taras, Ed.). JOURNAL OF MICROBIOLOGY & BIOLOGY EDUCATION, Vol. 7.
Ed(s): L. Brancaccio-Taras
author keywords: science communication; science literacy; public engagement; STEM education
UN Sustainable Development Goal Categories
4. Quality Education
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 7, 2023
2022 article
COVID-19: The Beginning of The Beginning
Koci, M. (2022, June 22).
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 17, 2022
2022 journal article
LL-37 transports immunoreactive cGAMP to activate STING signaling and enhance interferon-mediated host antiviral immunity
CELL REPORTS, 39(9).
MeSH headings : Antiviral Restriction Factors / immunology; Cathelicidins / immunology; Humans; Immunity, Innate; Interferons / immunology; Membrane Proteins / metabolism; Nucleotides, Cyclic
TL;DR:
LL-37, a human host defense peptide, can function as a transporter of cGAMP and activates robust interferon responses and host antiviral immunity in a STING-dependent manner and suggests new strategies for immunotherapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 11, 2022
2022 article
Viruses: The Most Abundant Thing You’ve Never Seen
Koci, M. (2022, June 22).
Source: ORCID
Added: August 17, 2022
2021 journal article
C-Terminal Amination of a Cationic Anti-Inflammatory Peptide Improves Bioavailability and Inhibitory Activity Against LPS-Induced Inflammation
FRONTIERS IN IMMUNOLOGY, 11.
author keywords: C-terminal amination; cellular uptake; bioavailability; Toll-like receptor; lipopolysaccharide neutralization; NF-к B signaling
MeSH headings : Amination; Animals; Anti-Inflammatory Agents / metabolism; Anti-Inflammatory Agents / pharmacokinetics; Anti-Inflammatory Agents / pharmacology; Biological Availability; Cathelicidins; Inflammation / chemically induced; Lipopolysaccharides / toxicity; Male; Mice; Mice, Inbred C57BL; Recombinant Proteins / metabolism; Recombinant Proteins / pharmacokinetics; Recombinant Proteins / pharmacology; Thymopentin
TL;DR:
A novel hybrid anti-inflammatory peptide that combines the active center of Cathelicidin 2 (CATH2) with thymopentin (TP5) with a successful modification based on the hypothesis that C-terminal amidation can enhance the cell uptake by increasing the hydrophobicity of the peptide is designed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 8, 2021
2020 journal article
A Novel Cecropin-LL37 Hybrid Peptide Protects Mice Against EHEC Infection-Mediated Changes in Gut Microbiota, Intestinal Inflammation, and Impairment of Mucosal Barrier Functions
FRONTIERS IN IMMUNOLOGY, 11.
author keywords: enrofloxacin; Escherichia coli; hybrid peptide; inflammation; microflora; mucosal barrier; O157; H7
MeSH headings : Animals; Antimicrobial Cationic Peptides / pharmacology; Cecropins / pharmacology; Escherichia coli Infections / pathology; Escherichia coli O157; Female; Gastrointestinal Microbiome / drug effects; Inflammation / microbiology; Inflammation / pathology; Intestinal Diseases / microbiology; Intestinal Diseases / pathology; Intestinal Mucosa / drug effects; Mice; Mice, Inbred C57BL; Recombinant Proteins / pharmacology; Cathelicidins
TL;DR:
Findings suggest that the novel hybrid peptide C-L could be developed into a new anti-inflammatory agent for use in animals or humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 10, 2020
2020 journal article
Attenuated Salmonella enterica Serovar Typhimurium, Strain NC983, Is Immunogenic, and Protective against Virulent Typhimurium Challenges in Mice
VACCINES, 8(4).
author keywords: Salmonella typhimurium; NC983; vaccine; in vivo; infection; C57BL/6 mice; BALB/c mice; IgG
TL;DR:
Oral delivery of strain NC983 was capable of fully protecting C57BL/6 and BALB/c mice against challenge with virulent Typhimurium, and results indicate that strainNC983 is a potential live attenuated vaccine strain that warrants further development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 19, 2021
2020 journal article
Complete Genome Sequences of Lactobacillus Strains C25 and P38, Isolated from Chicken Cecum
Microbiology Resource Announcements, 9(39).
Ed(s): D. Rasko
TL;DR:
The complete circular genome sequences of Lactobacillus crispatus strain C25, its plasmid, and LactOBacillus animalis strain P38; both strains were isolated from the cecum of 4-week-old chickens represent potential probiotic strains for poultry.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
15. Life on Land
(Web of Science)
Source: ORCID
Added: September 24, 2020
2020 article
Connecting the microbiome to host metabolites: understanding how the microbiome controls immune activity in birds
Koci, M., Ballou, A., Wei, X., Zhang, L., Liew, Z., & Ali, R. (2020, April). FASEB JOURNAL, Vol. 34.
TL;DR:
Analysis of the metabolites in serum and digesta from probiotic‐fed animals identified several metabolite changes correlate with the change in ATP levels in lymphocytes and putative changes in pro‐ and anti‐inflammatory cytokine production.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 12, 2020
2019 journal article
Development of a Highly Efficient Hybrid Peptide That Increases Immunomodulatory Activity Via the TLR4-Mediated Nuclear Factor-κB Signaling Pathway
International Journal of Molecular Sciences.
author keywords: immunoregulatory activity; cyclophosphamide; TLR4; MD-2; NF-kappa B
MeSH headings : Animals; Blotting, Western; Cell Survival / drug effects; Circular Dichroism; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Immunologic Factors / chemical synthesis; Immunologic Factors / chemistry; Immunologic Factors / pharmacology; Macrophages, Peritoneal / drug effects; Macrophages, Peritoneal / metabolism; Mice; Mice, Inbred BALB C; Peptides / chemical synthesis; Peptides / chemistry; Peptides / pharmacology; RAW 264.7 Cells
TL;DR:
Investigating the immunoregulatory effects and mechanisms of LTAa using a cyclophosphamide-immunosuppressed murine model effectively reversed immunosuppression by enhancing immune organ development, activating peritoneal macrophage phagocytosis, regulating T lymphocyte subsets, and increasing cytokine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: December 7, 2019
2017 journal article
A comparison of sequencing platforms and bioinformatics pipelines for compositional analysis of the gut microbiome
BMC MICROBIOLOGY, 17.
author keywords: 16S rRNA amplicon sequencing; microbiome analysis; microbiome; microbiome composition; next generation sequencing platforms; Bioinformatics pipeline; NGS bias
MeSH headings : Analysis of Variance; Animals; Bacteria / classification; Bacteria / genetics; Base Sequence; Biodiversity; Cecum / microbiology; Chickens / microbiology; Computational Biology / instrumentation; Computational Biology / methods; DNA, Bacterial / analysis; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Gastrointestinal Microbiome / genetics; Gene Library; High-Throughput Nucleotide Sequencing / instrumentation; High-Throughput Nucleotide Sequencing / methods; Microbial Consortia / genetics; Multivariate Analysis; Phylogeny; RNA, Ribosomal, 16S / genetics; Reproducibility of Results; Statistics as Topic
TL;DR:
Overall microbiome compositional profiles were comparable between platforms; however, average relative abundance of specific taxa varied depending on sequencing platform, library preparation method, and bioinformatics analysis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2017 journal article
An Attenuated Salmonella enterica Serovar Typhimurium Strain and Galacto-Oligosaccharides Accelerate Clearance of Salmonella Infections in Poultry through Modifications to the Gut Microbiome
Applied and Environmental Microbiology, 84(5).
Ed(s): J. Schottel
author keywords: chicken gut microbiome; gut microbiome modulation; prebiotics
MeSH headings : Animals; Bacterial Vaccines / pharmacology; Chickens; Female; Gastrointestinal Microbiome / drug effects; Oligosaccharides / administration & dosage; Poultry Diseases / microbiology; Poultry Diseases / prevention & control; Prebiotics / administration & dosage; Random Allocation; Salmonella Infections, Animal / microbiology; Salmonella Infections, Animal / prevention & control; Salmonella typhimurium / immunology; Vaccines, Attenuated / pharmacology
TL;DR:
It is demonstrated that a manipulation of the chicken gut microbiota by the administration of an attenuated Salmonella strain or prebiotic galacto-oligosaccharides (GOS) can promote resistance to Salmonellosis via increases of beneficial microorganisms that translate into a less hospitable gut microenvironment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018
2017 chapter
Astrovirus
In Food Microbiology Series: Laboratory Models for Foodborne Infections.
Source: ORCID
Added: December 19, 2018
2017 journal article
Efficacy of Feed Additives to Reduce the Effect of Naturally Occurring Mycotoxins Fed to Turkey Hen Poults Reared to 6 Weeks of Age
Poult. Sci.
author keywords: mycotoxin; turkey; feed additive; performance
MeSH headings : Aflatoxins / antagonists & inhibitors; Animal Feed / analysis; Animals; Diet / veterinary; Dietary Supplements / analysis; Female; Mycotoxins / antagonists & inhibitors; Protective Agents / pharmacology; Random Allocation; Trichothecenes / antagonists & inhibitors; Turkeys / growth & development; Turkeys / metabolism; Zearalenone / antagonists & inhibitors
TL;DR:
The feed additives used in this study did alleviate the effect of dietary mycotoxins to some degree, especially with respect to feed conversion.
(via Semantic Scholar)
Source: ORCID
Added: December 19, 2018
2017 journal article
Impact of Dietary Galacto-Oligosaccharide (GOS) on Chicken’s Gut Microbiota, Mucosal Gene Expression, and Salmonella Colonization
Frontiers in Veterinary Science, 4.
author keywords: chickens; immune; Salmonella; prebiotic; galacto-oligosaccharides
TL;DR:
Investigation of the effect of the prebiotic galacto-oligosaccharide (GOS) on the cecal microbiome and ultimately the carriage of Salmonella demonstrated that treatment with thePrebiotic GOS can modify both c Cecal tonsil gene expression and the cECal microbiome, suggesting that this type of treatment may be useful as a tool for altering the carriage in poultry.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 19, 2018
2016 journal article
Development of the Chick Microbiome: How Early Exposure Influences Future Microbial Diversity
Frontiers in Veterinary Science, 3.
author keywords: chicken; microbiome development; Salmonella; probiotic; gut development
TL;DR:
Assessment of the development of the cecal microbiome in chicks from hatch to 28 days of age with and without a live Salmonella vaccine and/or probiotic supplement demonstrates that these live microbial treatments do impact theDevelopment of the bacterial taxa found in the growing chicks.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 19, 2018
2016 journal article
Draft Genome Sequence of Lactobacillus crispatus C25 Isolated from Chicken Cecum
Genome Announcements, 4(6).
TL;DR:
The genome sequence of Lactobacillus crispatus strain C25, originally isolated from the cecum of 4-week-old chicken fed a standard diet, is presented, representing a potential probiotic strain for poultry.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 19, 2018
2016 journal article
Draft Genome Sequences of Lactobacillus animalis Strain P38 and Lactobacillus reuteri Strain P43 Isolated from Chicken Cecum
Genome Announcements, 4(6).
TL;DR:
These indigenous Lactobacillus isolates are potential probiotic organisms for poultry after isolated from the cecum content of a 4-week old chicken fed a diet supplemented with the prebiotic β(1-4)galacto-oligosaccharide (GOS).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 19, 2018
2016 journal article
Oral Administration of Astrovirus Capsid Protein Is Sufficient To Induce Acute Diarrhea In Vivo
MBio, 7(6).
MeSH headings : Administration, Oral; Avastrovirus / pathogenicity; Capsid Proteins / administration & dosage; Capsid Proteins / toxicity; Cell Membrane / chemistry; Cytoplasm / chemistry; Diarrhea / chemically induced; Diarrhea / pathology; Intestinal Mucosa / pathology; Sodium-Hydrogen Exchangers / analysis; Turkey
TL;DR:
Oral administration of purified recombinant turkey astrovirus 2 (TAstV-2) structural (capsid) protein induces acute diarrhea, increases barrier permeability, and causes relocalization of NHE3 in the small intestine, suggesting that rotavirus may not be alone in possessing enterotoxigenic activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018
2015 journal article
Poultry Body Temperature Contributes to Invasion Control through Reduced Expression of Salmonella Pathogenicity Island 1 Genes in Salmonella enterica Serovars Typhimurium and Enteritidis
Applied and Environmental Microbiology, 81(23), 8192–8201.
Contributors: B. Troxell n, N. Petri n, C. Daron n, R. Pereira *, M. Mendoza n, H. Hassan n , n
Ed(s): C. Elkins
MeSH headings : Animals; Cecum / microbiology; Cecum / physiology; Chickens; Genomic Islands; Liver / microbiology; Liver / physiology; Poultry Diseases / genetics; Poultry Diseases / metabolism; Poultry Diseases / microbiology; Salmonella Infections, Animal / genetics; Salmonella Infections, Animal / metabolism; Salmonella Infections, Animal / microbiology; Salmonella enteritidis / genetics; Salmonella enteritidis / physiology; Salmonella typhimurium / genetics; Salmonella typhimurium / physiology; Spleen / microbiology; Spleen / physiology; Temperature
TL;DR:
In vivo experiments using chicks demonstrated that numbers of viable S. Typhimurium or S. Enteritidis bacteria within the liver and spleen organ sites were ≥4 orders of magnitude lower than those within the ceca, indicating poor survival within these tissues or a reduced capacity to traverse the host epithelial layer and reach liver/spleen sites or both.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018
2014 journal article
Genetic Variation within the Mx Gene of Commercially Selected Chicken Lines Reveals Multiple Haplotypes, Recombination and a Protein under Selection Pressure
PLoS ONE, 9(9), e108054.
Contributors: J. Fulton *, J. Arango *, R. Ali n, E. Bohorquez n, A. Lund*, C. Ashwell n , P. Settar*, . N.P. O'Sullivan, n
Ed(s): A. Arez
MeSH headings : Animals; Base Sequence; Chickens / genetics; DNA; Haplotypes; Molecular Sequence Data; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Proteins / genetics; Recombination, Genetic; Selection, Genetic; Untranslated Regions
TL;DR:
Results suggest the conflicting reports in the literature describing the impact of the different SNP on chicken Mx function may be due to the varying context of haplotypes present in the populations studied.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018
2013 journal article
A mastoparan-derived peptide has broad-spectrum antiviral activity against enveloped viruses
PEPTIDES, 48, 96–105.
Contributors: C. Sample *, K. Hudak*, B. Barefoot*, n , M. Wanyonyi*, S. Abraham *, H. Staats *, E. Ramsburg*
author keywords: Mastoparan; Antiviral; Host defense peptide
MeSH headings : Animals; Antiviral Agents / chemistry; Antiviral Agents / pharmacology; Humans; Intercellular Signaling Peptides and Proteins; Invertebrates / chemistry; Mice; Microscopy, Electron; Peptides / chemistry; Peptides / pharmacology; Viruses / drug effects; Viruses / ultrastructure; Wasp Venoms / chemistry
TL;DR:
It is demonstrated for the first time that a mastoparan derivative has broad-spectrum antiviral activity in vitro and suggest that further investigation of the antiviral properties of mastopara peptides in vivo is warranted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 journal article
Broiler breeder feeding programs and trace minerals on maternal antibody transfer and broiler humoral immune response1
The Journal of Applied Poultry Research, 22(3), 499–510.
Contributors: E. Oviedo-Rondón n , N. Leandro n, R. Ali n, n , V. Moraes n & J. Brake n
author keywords: immunology; breeder; broiler; feeding program; organic mineral
TL;DR:
It was concluded that breeder feeding programs influenced humoral immune response to NDV vaccine in the broiler progeny, and 30% OTM may increase these responses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2012 chapter
Astrovirus Immunity
In Astrovirus Research: Essential Ideas, Everyday Impacts, Future Directions (Vol. 9781461447351, pp. 79–95).
Contributors: N. Krishna *, n & S. Guix *
Source: ORCID
Added: December 19, 2018
2012 chapter
Avian Astroviruses
In Astrovirus Research: Essential Ideas, Everyday Impacts, Future Directions (Vol. 9781461447351, pp. 151–180).
Contributors: M. Pantin-Jackwood *, D. Todd * & n
TL;DR:
This review focuses on avian astroviruses (AAstVs), in particular the recent advances in the understanding of AAstV molecular biology, and also history, diagnosis, treatment and control.
(via Semantic Scholar)
Source: ORCID
Added: December 19, 2018
2012 journal article
Comprehensive analysis of commercially available mouse antichicken monoclonal antibodies for cross-reactivity with peripheral blood leukocytes from commercial turkeys
POULTRY SCIENCE, 91(2), 383–392.
Contributors: R. Meyerhoff n, R. Ali n, K. Liu *, G. Huang * & *
author keywords: turkey; chicken; lymphocyte; cross-reactivity; cell surface marker
MeSH headings : Amino Acid Sequence; Animals; Antibodies, Monoclonal / immunology; CD8 Antigens / immunology; Chickens / immunology; Gene Expression Regulation; Leukocytes / immunology; Mice; Molecular Sequence Data; Turkeys / blood
TL;DR:
Investigation of a large panel of commercially available monoclonal antibodies specific for chicken leukocyte markers for their ability to specifically recognize the turkey homolog of their respective ligand using 2 different genetic lines of commercial turkeys strengthens understanding of the turkey immune system, its relative level of conservation with the chicken system, and adds to the list of reagents that can be reliably used to assess immune responses incommercial turkeys.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: ORCID, Web Of Science
Added: August 6, 2018
2012 article
Comprehensive analysis of commercially available mouse antichicken monoclonal antibodies for cross-reactivity with peripheral blood leukocytes from commercial turkeys (vol 91, pg 383, 2012)
Meyerhoff, R. R., Ali, R. A., Liu, K., Huang, G.-Q., & Koci, M. D. (2012, April 1). POULTRY SCIENCE, Vol. 91, pp. 1043–1043.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Direct fed microbial supplementation repartitions host energy to the immune system
JOURNAL OF ANIMAL SCIENCE, 90(8), 2639–2651.
Contributors: R. Qiu n, J. Croom n, R. Ali n, A. Ballou n, C. Smith n, C. Ashwell n , H. Hassan n , C. Chiang, n
author keywords: broiler; direct fed microbials; energy metabolism; gene expression; probiotics; systemic immune function
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens / immunology; Chickens / metabolism; Diet / veterinary; Dietary Supplements; Energy Metabolism / immunology; Enzyme-Linked Immunosorbent Assay; Erythrocytes / immunology; Gene Expression Regulation / immunology; Gram-Positive Bacteria / physiology; Immunoglobulin A / blood; Immunoglobulin G / blood; Male; Oxygen Consumption; Sheep; Time Factors
TL;DR:
Data indicate that supplementation with the direct fed microbial used in this study resulted in energy re-partitioning to the immune system and an increase in antibody production independent of changes in whole body metabolism or growth performance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 chapter
Avastrovirus, Astroviridae
In The Springer Index of Viruses. 2nd Edition (pp. 89–95).
Source: ORCID
Added: December 19, 2018
2011 journal article
Characterization of turkey inducible nitric oxide synthase and identification of its expression in the intestinal epithelium following astrovirus infection
Comparative Immunology, Microbiology and Infectious Diseases, 35(1), 63–69.
Contributors: R. Meyerhoff n, P. Nighot n, R. Ali n, A. Blikslager n & n
author keywords: Astrovirus; Enterocyte; Turkey; Inducible nitric oxide; Innate immunity
MeSH headings : Amino Acid Sequence; Animals; Astroviridae Infections / enzymology; Astroviridae Infections / veterinary; Astroviridae Infections / virology; Avastrovirus / physiology; Avian Proteins / genetics; Avian Proteins / metabolism; Bird Diseases / enzymology; Bird Diseases / virology; Enterocytes / enzymology; Enterocytes / pathology; Enterocytes / virology; Gene Expression; HEK293 Cells; Humans; Intestinal Mucosa / enzymology; Intestinal Mucosa / pathology; Intestinal Mucosa / virology; Lentivirus / genetics; Molecular Sequence Data; Nitric Oxide / biosynthesis; Nitric Oxide Synthase Type II / genetics; Nitric Oxide Synthase Type II / metabolism; Phylogeny; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Sequence Alignment; Transfection; Turkeys
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2011 journal article
Effects of broiler breeder genetic, diet type, and feeding program on maternal antibody transfer and development of lymphoid tissues in chicken progeny
The Journal of Applied Poultry Research, 20(4), 474–484.
Contributors: N. Leandro n, R. Ali n, n , V. Moraes n, R. Malheiros n, M. Wineland n, E. Oviedo-Rondón n
author keywords: breeder; bursa; feeding program; genetics; immunity; maternal antibody; spleen
TL;DR:
It was concluded that breeder feeding programs influence MatAb transfer and half-life, and may also affect the early development of lymphoid tissues.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2011 journal article
Maternal antibody transfer to broiler progeny varies among strains and is affected by grain source and cage density
Poultry Science, 90(12), 2730–2739.
Contributors: N. Leandro n, R. Ali n, n , V. Moraes n, P. Eusebio-Balcazar n, J. Jornigan n, R. Malheiros n, M. Wineland n, J. Brake n, E. Oviedo-Rondon n
author keywords: breeder nutrition; broiler progeny; genetic strain; lymphoid tissue
MeSH headings : Animal Feed / analysis; Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Antibodies / physiology; Chickens / genetics; Chickens / immunology; Diet / veterinary; Housing, Animal; Immunity, Maternally-Acquired / genetics; Immunity, Maternally-Acquired / physiology; Lymphoid Tissue
TL;DR:
The results of these experiments suggest that breeder strain and cage-density conditions affected MatAb transfer to progeny and embryo development of spleen and bursa.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2010 journal article
Astrovirus infection induces sodium malabsorption and redistributes sodium hydrogen exchanger expression
Virology, 401(2), 146–154.
Contributors: P. Nighot n, A. Moeser n, R. Ali n, A. Blikslager n & n
author keywords: Astrovirus; Viral enteritis; Malabsorption diarrhea; Sodium/hydrogen exchanger; Intestinal electrophysiology; Turkey
MeSH headings : Actins / metabolism; Animals; Astroviridae Infections / pathology; Astroviridae Infections / veterinary; Avastrovirus / pathogenicity; Cell Membrane / chemistry; Cytoplasm / chemistry; Gene Expression; Intestinal Mucosa / pathology; Intestinal Mucosa / ultrastructure; Poultry Diseases / pathology; Poultry Diseases / virology; Sodium / metabolism; Sodium-Hydrogen Exchangers / analysis; Turkeys
TL;DR:
Data suggest astrovirus infection induces sodium malabsorption, possibly through redistribution of specific sodium transporters, which results in the development of an osmotic diarrhoea in infants and the immunocompromised.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2010 journal article
Biological Effect of Naturally Occurring Mycotoxins Fed to Poults Reared to 21 Days of Age
International J. of Poultry Science, 9(9), 871–874.
TL;DR:
Feeding naturally occurring mycotoxins to poults can be used as a model to study interventions and the effects of AFL and DON in this study were reflective of what has been reported in the literature.
(via Semantic Scholar)
Source: ORCID
Added: December 19, 2018
2009 journal article
The effects of direct-fed microbial, primalac®, or salinomycin supplementation on intestinal lactate isomers and cecal volatile fatty acid concentrations in broilers
International Journal of Poultry Science, 8(2), 128–132.
TL;DR:
In the present study both dietary supplements, DFM and SAL, altered lactic acid and VFA concentrations in the cecum and intestines of experimental animals; however the full spectrum of mechanisms responsible for antibacterial properties and growth promotion associated with those changes remains to be elucidated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: December 19, 2018
2008 journal article
Broiler embryo bone development is influenced by incubator temperature, oxygen concentration and eggshell conductance at the plateau stage in oxygen consumption
BRITISH POULTRY SCIENCE, 49(6), 666–676.
Contributors: E. Oviedo-Rondón n , J. Small n, M. Wineland n, V. Christensen n, P. Mozdziak n , n , S. Funderburk n, D. Ort n, K. Mann n
MeSH headings : Animals; Body Weight; Bone Development / drug effects; Chick Embryo; Chickens / anatomy & histology; Chickens / growth & development; Chickens / metabolism; Egg Shell / physiology; Embryonic Development / drug effects; Femur / anatomy & histology; Incubators; Oxygen / metabolism; Oxygen / pharmacology; Temperature; Tibia / anatomy & histology
TL;DR:
The results indicated that elevated TEM during incubation increased RA between the two legs, mainly in the Low G strain, and suggest that late incubation conditions affect long bone development in broilers.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2008 journal article
Direct fed microbial, Primalac®, supplementation and jejunal glucose and proline transport in broiler chickens
International Journal of Poultry Science, 7(12), 1163–1166.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: December 19, 2018
2008 journal article
Genomic analysis of closely related astroviruses
JOURNAL OF VIROLOGY, 82(10), 5099–5103.
Contributors: E. Strain*, L. Kelley *, S. Schultz-Cherry *, S. Muse* & n
MeSH headings : Animals; Astroviridae Infections / virology; Avastrovirus / genetics; Avastrovirus / isolation & purification; Genome, Viral; Phylogeny; Poultry Diseases / virology; RNA, Viral / genetics; Recombination, Genetic; Sequence Analysis, DNA; Sequence Homology; Turkeys; United States
TL;DR:
The analysis of the capsid gene demonstrated evidence for both site-specific positive selection and purifying selection, and suggests that the TAstV species contains multiple subtypes and that recombination events have occurred across the astrovirus genome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2008 journal article
W1268 Mechanism of Astrovirus Induced Diarrhea
Gastroenterology, 134(4), A-668.
Sources: ORCID, Crossref, NC State University Libraries
Added: December 19, 2018
2007 journal article
Direct-fed microbial PrimaLac and salinomycin modulate whole-body and intestinal oxygen consumption and intestinal mucosal cytokine production in the broiler chick
POULTRY SCIENCE, 86(6), 1100–1106.
Contributors: M. Chichlowski n, J. Croom n, B. McBride *, L. Daniel n, G. Davis n & n
author keywords: broiler; direct-fed microbial; body energetics; cytokine
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Anti-Bacterial Agents / pharmacology; Chickens; Cytokines / metabolism; Diet / veterinary; Dietary Supplements; Gene Expression Regulation / drug effects; Intestinal Mucosa / drug effects; Intestinal Mucosa / metabolism; Intestines / drug effects; Lactobacillus; Oxygen Consumption / drug effects; Pyrans / pharmacology
TL;DR:
The reverse transcription-PCR data demonstrated that DFM consortium numerically altered both pro- and antiinflammatory cytokines within the ileum of 19-d posthatch broilers, suggesting that direct-fed microbials like PrimaLac increase metabolic efficiency via changes in intestinal physiology and metabolism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2007 journal article
Metabolic and physiological impact of probiotics or direct-fed-microbials on poultry: A brief review of current knowledge
International Journal of Poultry Science, 6(10), 694–704. http://www.scopus.com/inward/record.url?eid=2-s2.0-36048940317&partnerID=MN8TOARS
Source: ORCID
Added: December 19, 2018
2007 journal article
Microarchitecture and spatial relationship between bacteria and ileal, cecal, and colonic epithelium in chicks fed a direct-fed microbial, PrimaLac, and salinomycin
POULTRY SCIENCE, 86(6), 1121–1132.
Contributors: M. Chichlowski n, W. Croom n, F. Edens n, B. McBride *, R. Qiu n, C. Chiang *, L. Daniel n, G. Havenstein n, n
author keywords: broiler chicken; direct-fed microbial; scanning electron microscopy; histology
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Chickens / metabolism; Diet / veterinary; Dietary Supplements; Gastrointestinal Tract / drug effects; Gastrointestinal Tract / microbiology; Gastrointestinal Tract / ultrastructure; Intestinal Mucosa / drug effects; Intestinal Mucosa / microbiology; Lactobacillus / metabolism; Pyrans / pharmacology
TL;DR:
Spatial relationships, in this study, demonstrate the functionality of DFM and probiotics in preventing disease and supports previous observations that the feeding of salinomycin may alter intestinal function.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2006 journal article
Effect of genotype on whole-body and intestinal metabolic response to monensin in mice
Asian-Australasian Journal of Animal Sciences, 19(4), 554–562. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645764643&partnerID=MN8TOARS
Source: ORCID
Added: December 19, 2018
2005 review
Immunity and resistance to astrovirus infection
[Review of ]. VIRAL IMMUNOLOGY, 18(1), 11–16.
MeSH headings : Animal Diseases / immunology; Animals; Antibody Formation; Astroviridae Infections / immunology; Astroviridae Infections / veterinary; Humans; Immunity, Cellular; Immunity, Innate; Immunosuppression Therapy
TL;DR:
Until the role of the immune system in astrovirus infection or other enteric viruses is understood, the ability to treat and control gastrointestinal diseases will continue to be limited.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2004 journal article
Astrovirus-Induced Synthesis of Nitric Oxide Contributes to Virus Control during Infection
Journal of Virology, 78(3), 1564–1574.
Contributors: * , L. Kelley*, D. Larsen & S. Schultz-Cherry *
MeSH headings : Animals; Astroviridae Infections / immunology; Astroviridae Infections / virology; Cell Line; Chickens; Disease Models, Animal; Female; Humans; Immunity, Innate; Macrophage Activation; Macrophages / enzymology; Macrophages / immunology; Male; Mamastrovirus / immunology; Mamastrovirus / pathogenicity; Nitric Oxide / biosynthesis; Nitric Oxide Synthase / metabolism; Nitric Oxide Synthase Type II; Turkeys; Up-Regulation
TL;DR:
It is suggested that NO is important in limiting astrovirus replication and the first, to the authors' knowledge, to describe the potential role of innate immunity in astrov virus infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: December 19, 2018
2004 journal article
Development of a Multiplex Reverse Transcription–Polymerase Chain Reaction Diagnostic Test Specific for Turkey Astrovirus and Coronavirus
Avian Diseases, 48(3), 531–538.
Contributors: H. Sellers *, * , E. Linnemann*, L. Kelley* & S. Schultz-Cherry *
author keywords: multiplex RT-PCR; poult enteritis mortality syndrome; turkey coronavirus; turkey astrovirus; viral diagnostics
MeSH headings : Agriculture / methods; Animals; Astroviridae Infections / diagnosis; Astroviridae Infections / veterinary; Coronavirus, Turkey / genetics; DNA-Directed DNA Polymerase / genetics; Enteritis, Transmissible, of Turkeys / diagnosis; Mamastrovirus / genetics; Nucleocapsid Proteins / genetics; Poultry Diseases / diagnosis; Poultry Diseases / genetics; Reverse Transcriptase Polymerase Chain Reaction / methods; Sensitivity and Specificity; Turkeys / genetics
TL;DR:
A multiplex reverse transcription–polymerase chain reaction (RT-PCR) assay was developed for the simultaneous detection of two enteric viruses of poultry: turkey enteric coronavirus (TCV) and turkey astrovirus (TAstV).
(via Semantic Scholar)
Source: ORCID
Added: December 19, 2018
2003 journal article
Astrovirus Induces Diarrhea in the Absence of Inflammation and Cell Death
Journal of Virology, 77(21), 11798–11808.
Contributors: * , L. Moser*, L. Kelley*, D. Larsen, C. Brown * & S. Schultz-Cherry *
MeSH headings : Animals; Astroviridae Infections / veterinary; Astroviridae Infections / virology; Cell Death; Cell Line; Diarrhea / veterinary; Diarrhea / virology; Female; Humans; Inflammation; Male; Mamastrovirus / growth & development; Mamastrovirus / pathogenicity; Poult Enteritis Mortality Syndrome / physiopathology; Poult Enteritis Mortality Syndrome / virology; Poultry Diseases / physiopathology; Poultry Diseases / virology; Transforming Growth Factor beta / metabolism; Turkeys / virology
TL;DR:
It is demonstrated that TAstV-2 causes growth depression, decreased thymus size, and enteric infection in infected turkeys, and suggest that the turkey will be a useful small-animal model with which to study astrovirus pathogenesis and immunity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: December 19, 2018
2003 journal article
Examining the cellular pathways involved in influenza virus induced apoptosis
Avian Diseases, 47(SPEC. ISS.), 968–971. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141677673&partnerID=MN8TOARS
Source: ORCID
Added: December 19, 2018
2002 journal article
MeSH headings : Amino Acid Sequence; Animals; Astroviridae Infections / diagnosis; Astroviridae Infections / prevention & control; Astroviridae Infections / veterinary; Base Sequence; Birds; Chickens; Ducks; Humans; Mamastrovirus / classification; Mamastrovirus / genetics; Molecular Sequence Data; Open Reading Frames; Phylogeny; Poultry Diseases / diagnosis; Poultry Diseases / prevention & control; Poultry Diseases / virology; Protein Biosynthesis; Sequence Alignment; Sequence Homology, Amino Acid; Turkeys
Source: ORCID
Added: December 19, 2018
2002 journal article
Localization of astrovirus in experimentally infected turkeys as determined by in situ hybridization.
Veterinary Pathology, 39(5), 595–598. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036728382&partnerID=MN8TOARS
Source: ORCID
Added: December 19, 2018
2001 journal article
Inactivation of an Astrovirus Associated with Poult Enteritis Mortality Syndrome
Avian Diseases, 45(1), 76.
Contributors: S. Schultz-Cherry *, D. King & *
author keywords: astrovirus; poult enteritis mortality syndrome; PEMS; disinfectants
TL;DR:
In these studies, the stability of partially purified PEMS-associated astrovirus to inactivation with heat, laboratory disinfectants, and commercial disinfectants used in commercial turkey houses in an embryonated egg model system is examined.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: December 19, 2018
2000 journal article
Development of an RT-PCR diagnostic test for an avian astrovirus
Journal of Virological Methods, 90(1), 79–83.
Contributors: * , B. Seal * & S. Schultz-Cherry *
author keywords: turkey astrovirus; RT-PCR; poult enteritis mortality syndrome
MeSH headings : Animals; Astroviridae Infections / diagnosis; Astroviridae Infections / veterinary; Astroviridae Infections / virology; Capsid / genetics; DNA Primers; Mamastrovirus / genetics; Mamastrovirus / isolation & purification; Poultry Diseases / diagnosis; Poultry Diseases / virology; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Turkeys
TL;DR:
These studies describe the development of RT-PCR methods, which specifically detect regions of the viral capsid and polymerase genes, and demonstrate their use in detecting astrovirus infection in commercial turkey flocks.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: December 19, 2018
2000 journal article
Identifying agent(s) associated. with poult enteritis mortality syndrome: Importance of the thymus
AVIAN DISEASES, 44(2), 256–265.
Contributors: S. Schultz-Cherry *, D. Kapczynski, V. Simmons, * , C. Brown & H. Barnes*
author keywords: immunity; immunosuppression; lymphocytes; poult enteritis mortality syndrome; PEMS; T cells; thymus; turkeys
TL;DR:
The results of this study suggest that the thymus of infected birds harbors the agent(s) that can reproduce a PEMS-like disease in turkey poults.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science
Added: August 6, 2018
2000 journal article
Molecular characterization of an avian astrovirus
Journal of Virology, 74(13), 6173–6177.
Contributors: * , B. Seal * & S. Schultz-Cherry *
MeSH headings : Amino Acid Sequence; Animals; Astroviridae Infections / veterinary; Astroviridae Infections / virology; Base Sequence; DNA, Viral; Enteritis / veterinary; Enteritis / virology; Humans; Mamastrovirus / classification; Mamastrovirus / genetics; Mamastrovirus / isolation & purification; Molecular Sequence Data; RNA, Viral / analysis; Sequence Homology, Amino Acid; Turkeys / virology
TL;DR:
The nucleotide sequence, genomic organization, and predicted amino acid sequence of a turkey astrovirus isolated from poults with an emerging enteric disease is reported.
(via Semantic Scholar)
Source: ORCID
Added: December 19, 2018
1998 journal article
Interleukin-12 Overcomes Paclitaxel-Mediated Suppression of T-Cell Proliferation
Immunopharmacology and Immunotoxicology, 20(4), 473–492.
Contributors: D. Mullins *, * , C. Burger* & K. Elgert*
MeSH headings : Adjuvants, Immunologic / pharmacology; Animals; Antineoplastic Agents, Phytogenic / antagonists & inhibitors; Antineoplastic Agents, Phytogenic / pharmacology; Drug Interactions; Immunosuppressive Agents / antagonists & inhibitors; Immunosuppressive Agents / pharmacology; Interferon-gamma / biosynthesis; Interleukin-12 / pharmacology; Lymphocyte Activation / drug effects; Macrophages / drug effects; Macrophages / immunology; Male; Mice; Mice, Inbred BALB C; Paclitaxel / antagonists & inhibitors; Paclitaxel / pharmacology; T-Lymphocytes / drug effects; T-Lymphocytes / immunology
TL;DR:
It is suggested that chemotherapeutic paclitaxel regimens impart significant but reversible inhibition of lymphocyte populations, and IL-12 may be a useful ancillary immunotherapeuter to overcome pac litaxel-induced modulation of lymphocytes activities.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: December 19, 2018
journal article
Salmonella-attenuated strain and galacto-oligosaccharides accelerate clearance of Salmonella infections in poultry through modifications to the gut microbiome.
https://www.ncbi.nlm.nih.gov/pubmed/29269490
Source: ORCID
Added: December 19, 2018
Employment
Updated: October 1st, 2023 22:48
2023 - present
NC State University Raleigh, North Carolina, US
Co-Director, Animal Health and Nutrition Consortium
2018 - present
North Carolina State University Raleigh, NC, US
Professor
Prestage Department of Poultry Science
2012 - 2018
North Carolina State University Raleigh, NC, US
Associate Professor
Prestage Department of Poultry Sciecne
2004 - 2012
North Carolina State University Raleigh, NC, US
Assistant Professor
Poultry Science
2003 - 2004
University of Wisconsin Madison Madison, WI, US
Post-Doctoral Researcher
Medicine
Education
Updated: June 2nd, 2016 10:29
1999 - 2003
University of Georgia Athens, GA, US
Ph.D.
Pathology
1997 - 1999
University of Georgia Athens, GA, US
M.S.
Infectious Diseases
1993 - 1997
Virginia Polytechnic Institute and State University Blacksburg, VA, US
B.S. Biology microbiology/immunology option
Biology
Funding History
Funding history based on the linked ORCID record. Updated: February 5th, 2021 10:17
grant
September 1, 2020 - August 1, 2022
A COLLABORATIVE APPROACH TO MANAGING SARS-COV-2 WITHIN THE FOOD INDUSTRY; FILLING DATA GAPS AND IMPACTING BEHAVIORS
National Institute of Food and Agriculture
grant
August 1, 2020
Food Animal Fellowship: Understanding the microbiome of the modern poutlry production system
CALS-CVM Food Animal Initiative
grant
July 1, 2019 - July 1, 2021
Novel multiplex assays for the assessment of gut health, immune function, and stress in Poultry.
North Carolina Animal Feed and Nutrition Consortium
grant
March 1, 2019 - March 1, 2022
Chicken Nuggets on Mars: Using problem-based learning to teach Ag-STEM and inspire the next generation of food animal scientists.
National Institute of Food and Agriculture
grant
April 1, 2017 - March 31, 2018
Conference: From Omics to Function, Future Directions for Comparative Immunology, NACI Workshop, June 12-15, 2017, Raleigh, North Carolina
National Science Foundation - Directorate for Biological Sciences
grant
April 1, 2017 - June 1, 2018
Resistance in the Wild: Understanding Where, When, and Why Organisms Persist in the Wild
Triangle Center for Evolutionary Medicine
grant
April 1 - June 1, 2017
North American Comparative Immunology Workshop
North Carolina Biotechnology Center
grant
January 15, 2017 - January 14, 2019
STATE OF AG
National Institute of Food and Agriculture
grant
April 1, 2016 - March 1, 2018
Identification and Characterization of a Leukocyte ATP-Inducing Factor Stimulated by Probiotic Supplementation
U.S. Department of Agriculture
grant
August 1, 2015 - July 1, 2016
Development of Methods for Knockout Chickens: CRISPR-Cas Genome Editing To Understand Foodborne Pathogen-Host Interactions In Poultry
U.S. Department of Agriculture
grant
February 1, 2015 - February 1, 2018
Authentic Learning as a Means to Promote Student Enthusiasm for Science Careers by Establishing a Model Biotechnology Company in a Rural Tier 1 High School.
Burroughs Wellcome Fund
grant
January 1 - December 1, 2015
Academy for Global Food Animal Biosciences (AGfab): Feasibility, Planning & Design
NCSU Research and Innovation Seed Funding Program
contract
December 1, 2014 - May 1, 2015
Molecular assessment of poultry genetic material
Industrial Buffers LLC
grant
September 1, 2013 - August 1, 2016
Identification of Avian-Restricted, Temperature Regulated Loci in Non-Typhoid Salmonella and Their Contributions to Chicken Colonization
U.S. Department of Agriculture
grant
September 1, 2013 - August 1, 2016
Identification of Avian-Restricted, Temperature Regulated Loci in Non-Typhoid Salmonella and Their Contributions to Chicken Colonization
U.S. Department of Agriculture
grant
December 15, 2011 - December 14, 2014
DEVELOPMENT OF NOVEL SALMONELLA CONTROL PRACTICES AND INTEGRATED EDUCATION PROGRAM TO REDUCE SALMONELLOSIS
National Institute of Food and Agriculture
grant
September 1, 2011 - August 31, 2013
'HATCHING' TOMORROW`S LUMINARIES: RECRUITMENT, EDUCATION, AND MENTORING OF FUTURE MULTICULTURAL SCHOLARS AND LEADERS IN POULTRY SCIENCE
National Institute of Food and Agriculture
grant
July 1, 2011 - November 1, 2012
Chancellor's Innovation Fund - A Live Salmonella Vaccine
Chancellor's Innovation Fund (CIF)
grant
July 1, 2011 - November 1, 2012
Validation of a Live Salmonella Vaccine in Poultry
North Carolina Biotechnology Center
grant
September 1, 2010 - September 1, 2015
NC State BTEC Non-Competitive Continuation of Application FOA-EP-IDS-10-002 For Intermediate and Advanced Biomanufacturing Training
National Institutes of Health
grant
July 1, 2010 - June 1, 2013
Systems Approach to Reduce Ammonia and Particulate Emissions from Poultry Production Facilities
U.S. Department of Agriculture
grant
August 1, 2009 - December 1, 2010
Efficacy of LAAM Antiviral Technology Against Multiple Viral Families
LaamScience, Inc
grant
December 1, 2008 - November 1, 2013
Food Animal Functional Genomics Fellowship Program
U.S. Department of Agriculture
grant
July 1, 2007 - December 1, 2008
Enhancement of Gut-associated Immunity of Turkey Poults by In Ovo Feeding
U.S. Poultry and Egg Association
grant
August 1, 2006 - December 1, 2011
Identification of Genetic Factors Associated with Innate Resistance to Avian Influenza
Hy-Line International
grant
July 1, 2006 - June 1, 2026
Characterization of Type-2 Turkey Astrovirus Rate of Evolution
NCSU Faculty Research & Professional Development Fund
grant
July 1, 2006 - June 1, 2007
Turkey Astrovirus Type-2 Model of Infant Diarrhea
NCSU Faculty Research & Professional Development Fund
grant
December 1, 2004 - November 1, 2005
Mechanism of Astrovirus-Induced Diarrhea
UNC - UNC Chapel Hill (Prime--National Institutes of Health (NIH))
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