Works (49)

2023 journal article

A draft Diabrotica virgifera virgifera genome: insights into control and host plant adaption by a major maize pest insect

BMC GENOMICS, 24(1).

By: B. Coates*, K. Walden*, D. Lata*, N. Vellichirammal*, R. Mitchell*, M. Andersson*, R. McKay*, M. Lorenzen ...

author keywords: Genome assembly; Host plant specialization; Differential expression
Sources: Web Of Science, ORCID
Added: February 13, 2023

2022 journal article

The Genome of Rhyzopertha dominica (Fab.) (Coleoptera: Bostrichidae): Adaptation for Success

GENES, 13(3).

By: B. Oppert, A. Muszewska, K. Steczkiewicz, E. Satovic-Vuksic, M. Plohl, J. Fabrick, K. Vinokurov, I. Koloniuk ...

author keywords: Bostrichidae; insect reference genome; insecticide resistance; insect genetics; lesser grain borer; Rhyzopertha dominica
Sources: Web Of Science, ORCID
Added: April 18, 2022

2021 journal article

Characterization, expression patterns, and transcriptional responses of three core RNA interference pathway genes from Ostrinia nubilalis

JOURNAL OF INSECT PHYSIOLOGY, 129.

By: A. Cooper*, H. Song*, X. Shi*, Z. Yu*, M. Lorenzen, K. Silver*, J. Zhang*, K. Zhu*

author keywords: RNAi efficiency; Dicer 2; Argonaute 2; R2D2; European corn borer; Western corn rootworm; Diabrotica virgifera virgifera
Sources: Web Of Science, ORCID
Added: May 10, 2021

2021 journal article

Microinjection of Corn Planthopper, Peregrinus maidis, Embryos for CRISPR/Cas9 Genome Editing

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 3(169).

Sources: Web Of Science, ORCID
Added: May 17, 2021

2020 journal article

Molecular Characterizations of Double-Stranded RNA Degrading Nuclease Genes from Ostrinia nubilalis

Insects.

By: A. Cooper*, H. Song*, X. Shi*, Z. Yu*, M. Lorenzen, K. Silver*, J. Zhang*, K. Zhu*

author keywords: dsRNase; European corn borer; gene expression; REase; RNAi efficiency; substrate specificity
Source: ORCID
Added: September 28, 2020

2020 review

New Technologies for Studying Negative-Strand RNA Viruses in Plant and Arthropod Hosts

[Review of ]. MOLECULAR PLANT-MICROBE INTERACTIONS, 33(3), 382–393.

By: T. German*, M. Lorenzen, N. Grubbs & A. Whitfield

author keywords: virus-plant interactions
Sources: Web Of Science, ORCID
Added: August 3, 2020

2020 journal article

The impact of local population genetic background on the spread of the selfish element Medea-1 in red flour beetles

ECOLOGY AND EVOLUTION, 10(2), 863–874.

By: S. Cash n, M. Robert*, M. Lorenzen & F. Gould

author keywords: gene drive; maternal effect; Medea; selfish genetic element
Sources: Web Of Science, ORCID
Added: January 6, 2020

2020 journal article

Transcriptome analysis of life stages of the house cricket, Acheta domesticus, to improve insect crop production

SCIENTIFIC REPORTS, 10(1).

By: B. Oppert*, L. Perkin*, M. Lorenzen & A. Dossey*

Sources: Web Of Science, ORCID
Added: September 14, 2020

2019 journal article

Effects of targeting eye color in Tenebrio molitor through RNA interference of tryptophan 2,3‐dioxygenase ( vermilion ): Implications for insect farming

Archives of Insect Biochemistry and Physiology, 101(1), e21546.

By: B. Oppert*, F. Chu, S. Reyna, S. Pinzi, S. Adrianos*, L. Perkin*, M. Lorenzen

author keywords: agriculture; entomophagy; farming; gene expression; insect eye color; protein; RNA-Seq; Tenebrio molitor; vermilion
Sources: Web Of Science, ORCID, Crossref
Added: April 15, 2019

2019 journal article

Structural and functional insights into the Diabrotica virgifera virgifera ATP-binding cassette transporter gene family

BMC GENOMICS, 20(1).

By: F. Adedipe, N. Grubbs, B. Coates*, B. Wiegmman n & M. Lorenzen

author keywords: ATP-binding cassette (ABC) transporter; Phylogenetic; Transcriptome; RNA interference (RNAi); Corn rootworm
Sources: Web Of Science, ORCID
Added: December 16, 2019

2019 journal article

The distribution and spread of naturally occurring Medea selfish genetic elements in the United States

ECOLOGY AND EVOLUTION, 9(24), 14407–14416.

By: S. Cash n, M. Lorenzen & F. Gould

author keywords: maternal effect; Medea; red flour beetle; selfish genetic element
Sources: Web Of Science, ORCID
Added: February 10, 2020

2018 journal article

Cover Image

Archives of Insect Biochemistry and Physiology, 97(3), e21453.

By: F. Chu, W. Klobasa, N. Grubbs & M. Lorenzen

Sources: Crossref, ORCID
Added: January 25, 2020

2018 journal article

Genome of the small hive beetle (Aethina tumida, Coleoptera: Nitidulidae), a worldwide parasite of social bee colonies, provides insights into detoxification and herbivory

GigaScience, 7(12).

By: J. Evans*, D. McKenna*, E. Scully*, S. Cook*, B. Dainat*, N. Egekwu*, N. Grubbs, D. Lopez* ...

author keywords: Coleoptera; pollination; Apis mellifera; invasive pest; phytophagy; glycoside hydrolase; honey bee
Sources: Web Of Science, ORCID, Crossref
Added: February 11, 2019

2018 journal article

Metabolic pathway interruption: CRISPR/Cas9-mediated knockout of tryptophan 2,3-dioxygenase in Tribolium castaneum

JOURNAL OF INSECT PHYSIOLOGY, 107, 104–109.

By: S. Adrianos*, M. Lorenzen & B. Oppert*

author keywords: CRISPR; Ommochrome; Tryptophan 2,3-dioxygenase; Vermilion; Tribolium castaneum; Insect eye pigment
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Microinjection of Western Corn Rootworm, Diabrotica virgifera virgifera, Embryos for Germline Transformation, or CRISPR/Cas9 Genome Editing

Journal of Visualized Experiments, (134).

author keywords: Bioengineering; Issue 134; embryonic microinjection; functional genomics; germline transformation; transgenesis; CRISPR/Cas9 genome editing; western corn rootworm
Sources: Web Of Science, ORCID, Crossref
Added: October 16, 2018

2017 journal article

Agricultural production: assessment of the potential use of Cas9-mediated gene drive systems for agricultural pest control

Journal of Responsible Innovation, 5(sup1), S98–S120.

By: M. Scott, F. Gould, M. Lorenzen, N. Grubbs, O. Edwards* & D. O’Brochta*

author keywords: Gene drive; Cas9; sterile insect technique; agricultural pest insect
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Development and use of a piggyBac -based jumpstarter system in Drosophila suzukii

Archives of Insect Biochemistry and Physiology, 97(3), e21439.

author keywords: germline transformation; Minos; mutagenesis; piggyBac; transgenesis
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Germline transformation of the western corn rootworm, Diabrotica virgifera virgifera

Insect Molecular Biology, 26(4), 440–452.

By: F. Chu n, W. Klobasa, P. Wu, S. Pinzi, N. Grubbs, S. Gorski n, Y. Cardoza, M. Lorenzen

author keywords: Minos; piggyBac; small-scale rearing; embryonic microinjection
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2016 journal article

Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta

Insect Biochemistry and Molecular Biology, 76, 118–147.

By: M. Kanost, E. Arrese, X. Cao, Y. Chen, S. Chellapilla, M. Goldsmith, E. Grosse-Wilde, D. Heckel ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta

Insect Biochemistry and Molecular Biology, 76, 118–147.

By: M. Kanost*, E. Arrese*, X. Cao*, Y. Chen*, S. Chellapilla*, M. Goldsmith*, E. Grosse-Wilde*, D. Heckel* ...

author keywords: Lepidoptera; Insect; Tobacco hornworm; Synteny; Moth; Insect biochemistry; Innate immunity
Source: Crossref
Added: January 25, 2020

2015 journal article

Genes related to mitochondrial functions are differentially expressed in phosphine-resistant and -susceptible Tribolium castaneum

BMC GENOMICS, 16.

By: B. Oppert*, R. Guedes*, M. Aikins*, L. Perkin*, Z. Chen*, T. Phillips*, K. Zhu*, G. Opit* ...

author keywords: Anti-diuretic peptide; Cytochrome P450; Deltamethrin; Dihydrolipoamide dehydrogenase; Fumigants; Insecticide resistance; Gene expression; Phosphine resistance; Red flour beetle; RNA-Seq; Stored product pests; Tribolium castaneum
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

The ABCs of Eye Color in Tribolium castaneum: Orthologs of the Drosophila white, scarlet, and brown Genes

GENETICS, 199(3), 749-+.

By: N. Grubbs, S. Haas*, R. Beeman* & M. Lorenzen

author keywords: ABC transporters; eye pigmentation; evolution of development
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 book

Dictionary of Toxicology

(3rd ed.). Amsterdam: Academic Press.

By: E. Hodgson, M. Roe, R. Mailman & J. Chambers

Source: NC State University Libraries
Added: March 26, 2021

2014 conference paper

Genetics and Genomics of Tribolium Medea Elements

Presented at the 11th International Working Conference on Stored Product Protection, Chiang Mai, Thailand.

By: F. Chu, M. Lorenzen & W. Klobasa

Event: 11th International Working Conference on Stored Product Protection at Chiang Mai, Thailand on November 24-28, 2014

Source: NC State University Libraries
Added: March 26, 2021

2013 journal article

Functional analysis of the ATP-binding cassette (ABC) transporter gene family of Tribolium castaneum

BMC GENOMICS, 14.

By: G. Broehan*, T. Kroeger*, M. Lorenzen & H. Merzendorfer*

author keywords: ABC transporter; Coleoptera; dsRNA; Genome; RNA interference; Red flour beetle; Tribolium castaneum
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Genetic Structure of Tribolium castaneum (Coleoptera: Tenebrionidae) Populations in Mills

Environmental Entomology, 41(1), 188–199.

By: A. Semeao*, J. Campbell*, R. Beeman*, M. Lorenzen n, R. Whitworth* & P. Sloderbeck*

author keywords: Tribolium castaneum; genetic structure; F-ST; genetic fingerprinting; bottleneck
Sources: Crossref, ORCID
Added: January 25, 2020

2012 conference paper

Genetic structure of Tribolium castaneum (Coleoptera: Tenebrionidae) populations in mills

Presented at the 10th International Working Conference on Stored Product Protection, Estoril, Portugal.

By: A. Semeao, J. Campbell, R. Beeman, R. Whitworth, P. Sloderbeck & M. Lorenzen

Event: 10th International Working Conference on Stored Product Protection at Estoril, Portugal on June 27 - July 2, 2010

Source: NC State University Libraries
Added: March 26, 2021

2012 journal article

Transcriptome Profiling of the Intoxication Response of Tenebrio molitor Larvae to Bacillus thuringiensis Cry3Aa Protoxin

PLoS ONE, 7(4), e34624.

By: B. Oppert*, S. Dowd*, P. Bouffard*, L. Li*, A. Conesa*, M. Lorenzen n, M. Toutges*, J. Marshall* ...

Ed(s): S. Palli

Sources: Crossref, ORCID
Added: January 25, 2020

2011 chapter

RNAi in Agriculturally-Important Arthropods

In P. Grabowski (Ed.), RNA Processing (pp. 157–180).

By: K. Aronstein, B. Oppert & M. Lorenzen

Ed(s): P. Grabowski

Sources: Crossref, ORCID
Added: January 28, 2021

2010 journal article

RNA Interference as a Method for Target-Site Screening in the Western Corn Rootworm, Diabrotica Virgifera Virgifera

Journal of Insect Science, 10(162), 1–16.

By: A. Alves*, M. Lorenzen*, R. Beeman*, J. Foster* & B. Siegfried*

Sources: Crossref, ORCID
Added: January 25, 2020

2009 journal article

A NovelTenebrio molitorCadherin Is a Functional Receptor forBacillus thuringiensisCry3Aa Toxin

Journal of Biological Chemistry, 284(27), 18401–18410.

Sources: Crossref, ORCID, Web Of Science
Added: January 24, 2021

2009 journal article

BeetleBase in 2010: revisions to provide comprehensive genomic information for Tribolium castaneum

Nucleic Acids Research, 38(suppl_1), D437–D442.

Sources: Crossref, ORCID
Added: January 25, 2020

2009 journal article

Large-scale insertional mutagenesis of a coleopteran stored grain pest, the red flour beetle Tribolium castaneum, identifies embryonic lethal mutations and enhancer traps

BMC Biology, 7(1), 73.

Sources: Crossref, ORCID
Added: January 25, 2020

2009 journal article

The Red Flour Beetle, Tribolium castaneum (Coleoptera): A Model for Studies of Development and Pest Biology

Cold Spring Harbor Protocols, 2009(8), pdb.emo126-pdb.emo126.

By: S. Brown*, T. Shippy, S. Miller, R. Bolognesi, R. Beeman, M. Lorenzen, G. Bucher, E. Wimmer, M. Klingler

Sources: Crossref, ORCID
Added: January 25, 2020

2009 journal article

Tribolium castaneum Larval Gut Transcriptome and Proteome: A Resource for the Study of the Coleopteran Gut

Journal of Proteome Research, 8(8), 3889–3898.

By: K. Morris*, M. Lorenzen, Y. Hiromasa*, J. Tomich*, C. Oppert*, E. Elpidina*, K. Vinokurov*, J. Jurat-Fuentes*, J. Fabrick*, B. Oppert*

author keywords: Tribolium castaneum; microarray; proteomics; Coleoptera; insect control; insect gut
Sources: Crossref, ORCID
Added: January 25, 2020

2008 journal article

Analysis of repetitive DNA distribution patterns in the Tribolium castaneum genome

Genome Biology, 9(3), R61.

By: S. Wang*, M. Lorenzen, R. Beeman* & S. Brown*

Sources: Crossref, ORCID
Added: January 25, 2020

2008 journal article

Analysis of transcriptome data in the red flour beetle, Tribolium castaneum

Insect Biochemistry and Molecular Biology, 38(4), 380–386.

By: Y. Park*, J. Aikins*, L. Wang*, R. Beeman*, B. Oppert*, J. Lord*, S. Brown*, M. Lorenzen* ...

author keywords: Coleoptera; EST; GLEAN; gene model
Sources: Crossref, ORCID
Added: January 25, 2020

2008 journal article

The genome of the model beetle and pest Tribolium castaneum

Nature, 452(7190), 949–955.

By: S. Richards*, R. Gibbs*, G. Weinstock*, S. Brown*, R. Denell*, R. Beeman*, G. Bucher*, M. Friedrich ...

Sources: Crossref, ORCID
Added: January 25, 2020

2008 journal article

The maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposon

Proceedings of the National Academy of Sciences, 105(29), 10085–10089.

By: M. Lorenzen, A. Gnirke, J. Margolis, J. Garnes, M. Campbell, J. Stuart, R. Aggarwal, S. Richards, Y. Park, R. Beeman

author keywords: postzygotic; selfish gene; Tribolium; gene driver
Sources: Crossref, ORCID
Added: January 25, 2020

2008 journal article

Tubulin superfamily genes in Tribolium castaneum and the use of a Tubulin promoter to drive transgene expression

Insect Biochemistry and Molecular Biology, 38(8), 749–755.

By: K. Siebert*, M. Lorenzen*, S. Brown*, Y. Park* & R. Beeman*

author keywords: Tribolium; Tubulin; promoter; PiggyBac; EGFP; vermilion; transgene
Sources: Crossref, ORCID
Added: January 25, 2020

2007 journal article

piggyBac-based insertional mutagenesis in Tribolium castaneum using donor/helper hybrids

Insect Molecular Biology, 16(3), 265–275.

By: M. Lorenzen, T. Kimzey*, T. Shippy*, S. Brown*, R. Denell* & R. Beeman*

author keywords: piggyBac; Minos; germline transformation; EGFP; enhancer trap
Sources: Crossref, ORCID
Added: January 25, 2020

2006 journal article

Insights into social insects from the genome of the honeybee Apis mellifera

Nature, 443(7114), 931–949.

By: N. Libraries

Sources: Crossref, ORCID
Added: January 25, 2020

2005 journal article

Genetic Linkage Maps of the Red Flour Beetle, Tribolium castaneum, Based on Bacterial Artificial Chromosomes and Expressed Sequence Tags

Genetics, 170(2), 741–747.

By: M. Lorenzen*, Z. Doyungan*, J. Savard*, K. Snow*, L. Crumly*, T. Shippy*, J. Stuart*, S. Brown*, R. Beeman*

Sources: Crossref, ORCID
Added: January 25, 2020

2005 journal article

The Tribolium chitin synthase genes TcCHS1 and TcCHS2 are specialized for synthesis of epidermal cuticle and midgut peritrophic matrix

Insect Molecular Biology, 14(5), 453–463.

By: Y. Arakane*, S. Muthukrishnan*, K. Kramer*, C. Specht*, Y. Tomoyasu*, M. Lorenzen, M. Kanost*, R. Beeman*

author keywords: Tribolium castaneum; chitin synthase; RNAi; peritrophic matrix; cuticle
Sources: Crossref, ORCID
Added: January 25, 2020

2004 journal article

DIRS retroelements in arthropods: identification of the recently active TcDirs1 element in the red flour beetle Tribolium castaneum

Molecular Genetics and Genomics, 272(1), 47–56.

By: T. Goodwin*, R. Poulter*, M. Lorenzen & R. Beeman*

author keywords: insect; transposable element; tyrosine recombinase
Sources: Crossref, ORCID
Added: January 25, 2020

2003 journal article

piggyBac-mediated germline transformation in the beetle Tribolium castaneum

Insect Molecular Biology, 12(5), 433–440.

By: M. Lorenzen, A. Berghammer*, S. Brown*, R. Denell*, M. Klingler* & R. Beeman*

author keywords: piggyBac; germline transformation; EGFP; enhancer trap; Tribolium castaneum
Sources: Crossref, ORCID
Added: January 25, 2020

2002 journal article

Cloning and characterization of the Tribolium castaneum eye-color genes encoding tryptophan oxygenase and kynurenine 3-monooxygenase

Genetics, 160(1), 225–234.

By: M. Lorenzen, S. Brown*, R. Denell* & R. Beeman*

Sources: NC State University Libraries, ORCID
Added: March 26, 2021

2002 journal article

Transgene expression from the Tribolium castaneum Polyubiquitin promoter

Insect Molecular Biology, 11(5), 399–407.

By: M. Lorenzen, S. Brown*, R. Denell* & R. Beeman*

Sources: Crossref, ORCID
Added: January 25, 2020

1999 journal article

Using RNAi to investigate orthologous homeotic gene function during development of distantly related insects

Evolution and Development, 1(1), 11–15.

By: S. Brown*, J. Mahaffey, M. Lorenzen, R. Denell* & J. Mahaffey

Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

Employment

2009 - present

North Carolina State University Raleigh, NC, US
Associate professor Entomology

Education

1994 - 2000

Kansas State University Manhattan, KS, US
PhD Biology