Works (6)

Updated: August 12th, 2023 21:14

2017 journal article

Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds

MOLECULAR MICROBIOLOGY, 106(2), 223–235.

By: M. Milton*, C. Allen n, E. Feldmann n, B. Bobay n, D. Jung*, M. Stephens n, R. Melander n, K. Theisen n ...

MeSH headings : Anti-Bacterial Agents / pharmacology; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Bacterial Proteins / ultrastructure; Biofilms / drug effects; Francisella tularensis / metabolism; Gene Expression Regulation, Bacterial / genetics; Imidazoles / metabolism; Imidazoles / pharmacology; Protein Binding; Virulence / drug effects; Virulence Factors / genetics; Virulence Factors / metabolism
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Evaluation of ethyl N-(2-phenethyl) carbamate analogues as biofilm inhibitors of methicillin resistant Staphylococcus aureus

ORGANIC & BIOMOLECULAR CHEMISTRY, 14(28), 6853–6856.

By: M. Stephens n, N. Yodsanit* & C. Melander n

MeSH headings : Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Carbamates / chemistry; Carbamates / pharmacology; Humans; Methicillin-Resistant Staphylococcus aureus / drug effects; Methicillin-Resistant Staphylococcus aureus / physiology; Microbial Sensitivity Tests; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology; Staphylococcal Infections / drug therapy
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Marine sponge alkaloids as a source of anti-bacterial adjuvants

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 26(24), 5863–5866.

By: R. Melander n, H. Liu*, M. Stephens n, C. Bewley* & C. Melander

author keywords: Marine sponge; Pyrrole-imidazole alkaloid; Biofilm; Antibiotic; Adjuvant
MeSH headings : Acinetobacter baumannii / drug effects; Alkaloids / chemistry; Alkaloids / metabolism; Alkaloids / pharmacology; Animals; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacology; Dose-Response Relationship, Drug; Imidazoles / chemistry; Imidazoles / pharmacology; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Molecular Structure; Porifera; Pyrroles / chemistry; Pyrroles / pharmacology; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Potentiation of Francisella resistance to conventional antibiotics through small molecule adjuvants

MEDCHEMCOMM, 7(1), 128–131.

Source: Web Of Science
Added: August 6, 2018

2016 journal article

Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida

MEDCHEMCOMM, 7(10), 1952–1956.

By: M. Stephens n, N. Yodsanit* & C. Melander n

Source: Web Of Science
Added: August 6, 2018

2015 journal article

Aryl amide small-molecule inhibitors of microRNA miR-21 function

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 25(21), 4793–4796.

By: Y. Naro*, M. Thomas*, M. Stephens n, C. Connelly n & A. Deiters*

author keywords: miR-21; MicroRNA; Small-molecule inhibitors; Cancer; Gene regulation; Post-transcriptional regulation
MeSH headings : Amides / chemical synthesis; Amides / chemistry; Amides / pharmacology; Cell Line, Tumor; Dose-Response Relationship, Drug; HeLa Cells; Humans; MicroRNAs / antagonists & inhibitors; MicroRNAs / genetics; Molecular Structure; Small Molecule Libraries / chemical synthesis; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018