Michaela Copp
College of Engineering
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Works (3)
Updated: August 7th, 2023 21:16
2022 article
Comet assay for quantification of the increased DNA damage burden in primary human chondrocytes with aging and osteoarthritis
Copp, M. E., Chubinskaya, S., Bracey, D. N., Shine, J., Sessions, G., Loeser, R. F., & Diekman, B. O. (2022, August 22). AGING CELL.
author keywords: arthritis; cartilage; single-cell gel electrophoresis
MeSH headings : Adult; Aged; Aging / genetics; Cadaver; Cartilage, Articular / metabolism; Cells, Cultured; Chondrocytes / metabolism; Comet Assay; DNA Damage / genetics; Humans; Middle Aged; Osteoarthritis / genetics; Osteoarthritis / metabolism
Source: Web Of Science
Added: September 6, 2022
2021 journal article
The combination of mitogenic stimulation and DNA damage induces chondrocyte senescence
OSTEOARTHRITIS AND CARTILAGE, 29(3), 402–412.
author keywords: SA-beta-gal; DNA damage; Osteoarthritis; Aging; TGF- beta 1; bFGF
MeSH headings : Animals; Ankle Joint; Cartilage, Articular / cytology; Cartilage, Articular / drug effects; Cartilage, Articular / metabolism; Cellular Senescence / drug effects; Cellular Senescence / genetics; Chemokine CCL2 / drug effects; Chemokine CCL2 / genetics; Chondrocytes / drug effects; Chondrocytes / metabolism; Cyclin-Dependent Kinase Inhibitor p16 / drug effects; Cyclin-Dependent Kinase Inhibitor p16 / metabolism; DNA Damage / genetics; Fibroblast Growth Factor 2 / pharmacology; Gene Expression / drug effects; Histones / drug effects; Histones / metabolism; Horses; Humans; In Vitro Techniques; Inflammation / genetics; Insulin-Like Growth Factor Binding Protein 3 / drug effects; Insulin-Like Growth Factor Binding Protein 3 / genetics; Interleukin-6 / genetics; Matrix Metalloproteinase 13 / drug effects; Matrix Metalloproteinase 13 / genetics; Mitogens / pharmacology; Stifle; Transforming Growth Factor beta1 / pharmacology; beta-Galactosidase / drug effects; beta-Galactosidase / metabolism
Source: Web Of Science
Added: March 29, 2021
2019 article
CONTROLLED INDUCTION AND TARGETED ELIMINATION OF P16(INK4A)-HIGH CHONDROCYTES TO INVESTIGATE SENESCENCE-MEDIATED CARTILAGE DYSFUNCTION
Sessions, G. A., Sinkler, M. A., Copp, M. E., & Diekman, B. O. (2019, April). OSTEOARTHRITIS AND CARTILAGE, Vol. 27, pp. S97–S97.
www.oarsijournal.com (publisher PDF)
Source: Web Of Science
Added: April 20, 2020
