Margaret Elizabeth Gruen

Relationship between engagement with the impossible task, cognitive testing, and cognitive questionnaires in a population of aging dogs

FRONTIERS IN VETERINARY SCIENCE, 9.

Response to Hansen Wheat et al.: Additional analysis further supports the early emergence of cooperative communication in dogs compared to wolves raised with more human exposure

Salomons, H., Smith, K. C. M., Callahan-Beckel, M., Callahan, M., Levy, K., Kennedy, B. S. S., … Hare, B. (2023, February 21). LEARNING & BEHAVIOR, Vol. 2.

Sleep and cognition in aging dogs. A polysomnographic study

FRONTIERS IN VETERINARY SCIENCE, 10.

2022 AAHA Pain Management Guidelines for Dogs and Cats

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 58(2), 55–76.

Canine Geriatric Syndrome: A Framework for Advancing Research in Veterinary Geroscience

FRONTIERS IN VETERINARY SCIENCE, 9.

Relationship between hearing, cognitive function, and quality of life in aging companion dogs

Fefer, G., Khan, M. Z., Panek, W. K., Case, B., Gruen, M. E., & Olby, N. J. (2022, August 6). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 8.

Static posturography as a novel measure of the effects of aging on postural control in dogs

PLOS ONE, 17(7).

Use of Cognitive Testing, Questionnaires, and Plasma Biomarkers to Quantify Cognitive Impairment in an Aging Pet Dog Population

JOURNAL OF ALZHEIMERS DISEASE, 87(3), 1367–1378.

A Literature Review: Pet Bereavement and Coping Mechanisms

Park, R. M., Royal, K. D., & Gruen, M. E. (2021, June 7). JOURNAL OF APPLIED ANIMAL WELFARE SCIENCE, Vol. 6.

Aggression, overview – Dogs

In L. P. Tilley & F. W. K. Smith (Eds.), Blackwell’s Five-Minute Veterinary Consult: Canine and Feline (7th ed.). New York: Wiley-Blackwell.

Assessment of Sensory Thresholds in Dogs using Mechanical and Hot Thermal Quantitative Sensory Testing

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 10(176).

Association between Dog Owner Demographics and Decision to Seek Veterinary Care

VETERINARY SCIENCES, 8(1).

Cooperative Communication with Humans Evolved to Emerge Early in Domestic Dogs

CURRENT BIOLOGY, 31(14), 3137-+.

Dog cognitive development: a longitudinal study across the first 2 years of life

ANIMAL COGNITION, 24(2), 311–328.

Evaluation of Pexion(R) (imepitoin) for treatment of storm anxiety in dogs: A randomised, double-blind, placebo-controlled trial

VETERINARY RECORD, 188(9).

Evaluation of a nutritional supplement for the alleviation of pain associated with feline degenerative joint disease: a prospective, randomized, stratified, double-blind, placebo-controlled clinical trial

Cunningham, R., Gruen, M. E., Thomson, A., & Lascelles, B. D. X. (2021, November 1). JOURNAL OF FELINE MEDICINE AND SURGERY, Vol. 11.

Feline compulsive disorders

In L. P. Tilley & F. W. K. Smith (Eds.), Blackwell’s Five-Minute Veterinary Consult: Canine and Feline (7th ed.). New York: Wiley-Blackwell.

Feline housesoiling

In L. P. Tilley & F. W. K. Smith (Eds.), Blackwell’s Five-Minute Veterinary Consult: Canine and Feline (7th ed.). New York: Wiley-Blackwell.

Frunevetmab, a felinized anti-nerve growth factor monoclonal antibody, for the treatment of pain from osteoarthritis in cats

Gruen, M. E., Myers, J. A. E., Tena, J.-K. S., Becskei, C., Cleaver, D. M., & Lascelles, B. D. X. (2021, November 1). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 11.

Improved neurocognitive performance in FIV infected cats following treatment with the p75 neurotrophin receptor ligand LM11A-31

JOURNAL OF NEUROVIROLOGY, 27(2), 302–324.

Plasma Amyloid Beta Concentrations in Aged and Cognitively Impaired Pet Dogs

MOLECULAR NEUROBIOLOGY, 58(2), 483–489.

Randomized, Placebo-Controlled Prospective Clinical Trial Evaluating the Efficacy of the Assisi Anti-anxiety Device (Calmer Canine) for the Treatment of Canine Separation Anxiety

FRONTIERS IN VETERINARY SCIENCE, 8.

Refinement of the Feline Musculoskeletal Pain Index (FMPI) and development of the short-form FMPI

Enomoto, M., Lascelles, B. D. X., Robertson, J. B., & Gruen, M. E. (2021, May 18). JOURNAL OF FELINE MEDICINE AND SURGERY, Vol. 24.

Robenacoxib shows efficacy for the treatment of chronic degenerative joint disease-associated pain in cats: a randomized and blinded pilot clinical trial

Scientific Reports Volume, 11(1), 7721.

Sustained Gaze Is a Reliable In-home Test of Attention for Aging Pet Dogs

FRONTIERS IN VETERINARY SCIENCE, 8.

A Systematic Literature Review of Animal-Assisted Interventions in Oncology (Part I): Methods and Results

Integrative Cancer Therapies, 19, 1–19.

A Systematic Literature Review of Animal-Assisted Interventions in Oncology (Part II): Theoretical Mechanisms and Frameworks

[Review of ]. INTEGRATIVE CANCER THERAPIES, 19.

A functional linear modeling approach to sleep-wake cycles in dogs

SCIENTIFIC REPORTS, 10(1).

Cognitive characteristics of 8-to 10-week-old assistance dog puppies

ANIMAL BEHAVIOUR, 166, 193–206.

Development of a checklist for the detection of degenerative joint disease-associated pain in cats

Journal of Feline Medicine and Surgery, 22(12), 1137–1147.

Do dog breeds differ in pain sensitivity? Veterinarians and the public believe they do

PLOS ONE.

Evaluation of repeated dosing of a dexmedetomidine oromucosal gel for treatment of noise aversion in dogs over a series of noise events

VETERINARY RECORD, 187(12).

Growing old with grace: old cats should learn new tricks

In M. E. Herron, D. F. Horwitz, C. Siracusa, & S. Dale (Eds.), Decoding Your Cat. Boston, MA: Houghton Mifflin Harcourt.

Improved neurocognitive performance in FIV infected cats following treatment with the p75 neurotrophin receptor ligand LM11A-31

Fogle, J. E., Hudson, L., Thomson, A., Sherman, B., Gruen, M., Lacelles, B. D., … Meeker, R. B. (2020, June 17). (Vol. 6). Vol. 6.

Pain and Problem Behavior in Cats and Dogs

ANIMALS, 10(2).

Plasma Neurofilament Light Chain as a Translational Biomarker of Aging and Neurodegeneration in Dogs

MOLECULAR NEUROBIOLOGY, 57(7), 3143–3149.

Preliminary Evaluation of a Wearable Sensor System for Heart Rate Assessment in Guide Dog Puppies

IEEE SENSORS JOURNAL, 20(16), 9449–9459.

Does the cognitive bias test in dogs depend on spatial learning?

Journal of Veterinary Behavior, 33, 1–6.

Functional linear modeling of activity data shows analgesic-mediated improved sleep in dogs with spontaneous osteoarthritis pain

Scientific Reports.

Development and preliminary validity and reliability of the montreal instrument for cat arthritis testing, for use by caretaker/owner, MI-CAT(C), via a randomised clinical trial

Applied Animal Behaviour Science, 200, 96–105.

Drugs affecting animal behavior

In J. E. Reviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 416–450). New York: Wiley.

Enrichment Preferences of FIV-Infected and Uninfected Laboratory-Housed Cats

Viruses, 10(7), 353.

Pilot study evaluating the effect of feeding method on overall activity of neutered indoor pet cats

Journal of Veterinary Behavior, 25, 9–13.

Which Drugs Are Used to Treat Cognitive Dysfunction Syndrome?

Clinician's Brief. https://www.cliniciansbrief.com/article/which-drugs-are-used-treat-cognitive-dysfunction-syndrome

A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades

TOXICOLOGY AND APPLIED PHARMACOLOGY, 314, 109–117.

Attitudes of small animal practitioners toward participation in veterinary clinical trials

Journal of the American Veterinary Medical Association, 250(1), 86–97.

Behavior problems in old cats

In D. F. Horwitz (Ed.), Blackwell’s Five-Minute Veterinary Consult Clinical Companion: Canine and Feline Behavior (2nd ed.). New York: Wiley-Blackwell.

Caregiver placebo effect in analgesic clinical trials for cats with naturally occurring degenerative joint disease-associated pain

Veterinary Record, 180(19), 473–473.

Effect of wearing a Telemetry jacket on behavioral and physiologic parameters of dogs in the open-field test

Journal of the American Association for Laboratory Animal Science, 56(4), 382–389.

Endogenous Oxytocin, Vasopressin, and Aggression in Domestic Dogs

Frontiers in Psychology, 8.

Evaluation of serum cytokines in cats with and without degenerative joint disease and associated pain

Veterinary Immunology and Immunopathology, 183, 49–59.

Generation of a stable transgenic swine model expressing a porcine histone 2b-egfp fusion protein for cell tracking and chromosome dynamics studies

PLoS One, 12(1).

Joint pain in pet dogs and cats

In L. Arendt-Nielsen & S. Perrod (Eds.), Pain in the Joints (pp. 45–58). Philadelphia, PA: Wolters Kluwer.

Replicate effects and test-retest reliability of quantitative sensory threshold testing in dogs with and without chronic pain

Veterinary Anaesthesia and Analgesia, 44(3), 615–624.

The Use of Functional Data Analysis to Evaluate Activity in a Spontaneous Model of Degenerative Joint Disease Associated Pain in Cats

PLOS ONE, 12(1), e0169576.

The use of trazodone to facilitate calm behavior after elective orthopedic surgery in dogs: Results and lessons learned from a clinical trial

Journal of Veterinary Behavior, 22, 41–45.

A Feline-Specific Anti-Nerve Growth Factor Antibody Improves Mobility in Cats with Degenerative Joint Disease-Associated Pain: A Pilot Proof of Concept Study

Journal of Veterinary Internal Medicine, 30(4), 1138–1148.

A comparison of serum and plasma cytokine values using a multiplexed assay in cats

Veterinary Immunology and Immunopathology, 182, 69–73.

Aggression, overview – Dogs

In L. P. Tilley & F. W. K. Smith (Eds.), Blackwell’s Five-Minute Veterinary Consult; Canine and Feline (6th ed., pp. 46–49). Ames, Iowa: John Wiley and Sons.

Efficacy of a single dose of trazodone hydrochloride given to cats prior to veterinary visits to reduce signs of transport- and examination-related anxiety

Journal of the American Veterinary Medical Association, 249(2), 202–207.

Evaluation of Clinical Metrology Instrument in Dogs with Osteoarthritis

Journal of Veterinary Internal Medicine, 30(3), 836–846.

Feline compulsive disorders

In L. P. Tilley & F. W. K. Smith (Eds.), Blackwell’s Five-Minute Veterinary Consult: Canine and Feline (6th edition, pp. 297–298). Ames, Iowa: John Wiley and Sons.

Feline housesoiling

In L. P. Tilley & F. W. K. Smith (Eds.), Blackwell’s Five-Minute Veterinary Consult; Canine and Feline (6th ed., pp. 639–642). Ames, Iowa: John Wiley and Sons.

Widespread somatosensory sensitivity in naturally occurring canine model of osteoarthritis

PAIN, 157(6), 1325–1332.

A test for the evaluation of emotional reactivity in Labrador retrievers used for explosives detection

JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH, 10(2), 94–102.

Criterion Validation Testing of Clinical Metrology Instruments for Measuring Degenerative Joint Disease Associated Mobility Impairment in Cats

PLOS ONE, 10(7), e0131839.

Olfactory discrimination and generalization of ammonium nitrate and structurally related odorants in Labrador retrievers

Animal Cognition, 18(6), 1255–1265.

Response to Letter to the Editor "LSU-SVM Shelter Medicine Program"

The use of an open-field model to assess sound-induced fear and anxiety-associated behaviors in Labrador retrievers

JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH, 10(4), 338–345.

Acquisition of a visual discrimination and reversal learning task by Labrador retrievers

ANIMAL COGNITION, 17(3), 787–792.

CLINICAL TRIALS INVOLVING CATS What factors affect owner participation?

JOURNAL OF FELINE MEDICINE AND SURGERY, 16(9), 727–735.

Chronic kidney disease in cats

Detection of Clinically Relevant Pain Relief in Cats with Degenerative Joint Disease Associated Pain

JOURNAL OF VETERINARY INTERNAL MEDICINE, 28(2), 346–350.

Prevalence and classification of chronic kidney disease in cats randomly selected from four age groups and in cats recruited for degenerative joint disease studies

JOURNAL OF FELINE MEDICINE AND SURGERY, 16(6), 465–472.

Relationship Between Degenerative Joint Disease, Pain, and Bartonella spp. Seroreactivity in Domesticated Cats

Journal of Veterinary Internal Medicine, 29(1), 21–27.

Training Veterinary Students in Shelter Medicine: A Service-Learning Community-Classroom Technique

JOURNAL OF VETERINARY MEDICAL EDUCATION, 41(1), 83–89.

Use of trazodone to facilitate postsurgical confinement in dogs

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 245(3), 296–301.

Use of trazodone to facilitate postsurgical confinement in dogs Response

Conditioning laboratory cats to handling and transport

LAB ANIMAL, 42(10), 385–389.

How I Treat Cognitive Dysfunction

Clinician’s Brief, 11(12), 13–18.

The use of a T-maze to measure cognitive-motor function in cats (Felis catus)

JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH, 8(1), 32–39.

Animal Behavior Case of the Month

Gruen, M. E., & Sherman, B. L. (2012, November 15). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 241, pp. 1293–1295.

Animal Behavior Case of the Month

Journal of the American Veterinary Medical Association, 241(11), 1445–1447.

Owner-assessed indices of quality of life in cats and the relationship to the presence of degenerative joint disease

JOURNAL OF FELINE MEDICINE AND SURGERY, 14(12), 863–870.

Use of trazodone as an adjunctive agent in the treatment of canine anxiety disorders: 56 cases (1995-2007)

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 233(12), 1902–1907.