Works (80)

Updated: May 30th, 2024 05:00

2024 article

Antimicrobial Resistance Characteristics of Fecal <i>Escherichia coli</i> and <i>Enterococcus</i> Species in US Goats: 2019 National Animal Health Monitoring System Enteric Study

Gensler, C. A., Hempstead, S. C., Keelara, S., Fedorka-Cray, P. J., Urie, N. J., Wiedenheft, A. M., … Jacob, M. E. (2024, March 18). FOODBORNE PATHOGENS AND DISEASE.

By: C. Gensler n, S. Hempstead n, S. Keelara n, P. Fedorka-Cray n, N. Urie*, A. Wiedenheft*, K. Stuart*, K. Marshall*, M. Jacob n

author keywords: NAHMS; Enterococcus; E. coli; STEC; goat; AMR
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: April 8, 2024

2024 journal article

Characteristics of antimicrobial resistance in <i>Escherichia coli</i> isolated from retail meat products in North Carolina

PLOS ONE, 19(1).

By: M. Aworh n, S. Thakur n, C. Gensler n, E. Harrell n, L. Harden n, P. Fedorka-Cray n, M. Jacob n

TL;DR: The lack of an association between MDR E. coli in retail meat and antibiotic use claim, including those with no indication of antimicrobial use, suggests that additional research is required to understand the origin of resistance. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 26, 2024

2024 article

Diagnostic utility of the total nucleated cell count for differentiation of septic and sterile peritoneal effusions in dogs

Didomenico, A. E., Jacob, M. E., Stowe, D. M., & Gruber, E. J. (2024, February 6). VETERINARY CLINICAL PATHOLOGY, Vol. 2.

By: A. Didomenico n, M. Jacob n, D. Stowe n & E. Gruber n

author keywords: abdominal effusion; bacteria; fluid analysis; peritonitis; secondary peritonitis
TL;DR: Total nucleated cell counts and absolute neutrophil counts aid in the differentiation of septic and non-septic peritoneal effusions with similar diagnostic utility but are not sufficiently sensitive or specific to use without concurrent microscopic evaluation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 8, 2024

2024 journal article

Impact of florfenicol dosing regimen on the phenotypic and genotypic resistance of enteric bacteria in steers

SCIENTIFIC REPORTS, 14(1).

By: J. Halleran n, H. Sylvester n, M. Jacob n, B. Callahan n, R. Baynes n & D. Foster n

Sources: Web Of Science, NC State University Libraries
Added: April 8, 2024

2024 journal article

Phenotypic and Genotypic Characterizations of Antimicrobial-Resistant <i>Escherichia coli</i> Isolates from Diverse Retail Meat Samples in North Carolina During 2018-2019

FOODBORNE PATHOGENS AND DISEASE, 1.

By: A. Abdelrahim n, E. Harrell n, P. Fedorka-Cray n, M. Jacob n & S. Thakur n

author keywords: antimicrobial resistance; Escherichia coli; retail meats; whole genome sequencing; antimicrobial susceptibility testing; multidrug resistance
Sources: Web Of Science, NC State University Libraries
Added: March 18, 2024

2024 article

Prevalence and molecular epidemiology of carbapenemase-producing Enterobacterales isolated from dog and cat faeces submitted to veterinary laboratories in the USA

Dietrich, J., Lecuyer, T. E., Hendrix, G. K., Burbick, C. R., Jacob, M. E., Byrne, B. A., … Cole, S. D. (2024, May 15). ZOONOSES AND PUBLIC HEALTH.

By: J. Dietrich, T. Lecuyer, G. Hendrix, C. Burbick, M. Jacob, B. Byrne, K. Olsen, M. Mitchell ...

author keywords: carbapenemase-producing Enterobacterales; cats; companion animals; dogs; prevalence
Source: Web Of Science
Added: May 28, 2024

2023 journal article

Comparative growth dynamics of bacterial and fungal contaminants in bupivacaine liposomal injectable suspension, bupivacaine 0.5%, and propofol

PLOS ONE, 18(2).

By: A. Wallace n, L. Love n, C. Gensler n, M. Jacob n, J. Robertson n & K. Messenger n

Ed(s): G. Nevárez-Moorillón

MeSH headings : Propofol / pharmacology; Bupivacaine / pharmacology; Prospective Studies; Anesthetics; Escherichia coli; Anesthetics, Local / pharmacology
TL;DR: Bacterial and fungal contaminant growth in artificially inoculated BLIS is organism dependent and extra-label handling of BLIS should only be undertaken with caution and with adherence to strict aseptic technique. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 17, 2023

2023 article

Draft Genome Sequences of Escherichia coli and Enterococcus faecalis Coisolated from Polymicrobial Extraintestinal Infections of Chickens and Turkeys

Walker, G. K., Harden, L., Suyemoto, M. M., Thakur, S., Jacob, M., & Borst, L. B. (2023, February 21). MICROBIOLOGY RESOURCE ANNOUNCEMENTS, Vol. 2.

By: G. Walker n, L. Harden n, M. Suyemoto n, S. Thakur n, M. Jacob n & L. Borst n

TL;DR: It is reported that draft genome sequences of 18 APEC and 18 E. faecalis strains coisolated from lesions of diseased poultry with colisepticemia are reported. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 20, 2023

2023 article

Draft genome sequences of 12 Escherichia coli co-isolated with Enterococcus spp. from dogs with polybacterial bacteriuria at a veterinary hospital

Walker, G. K., Harden, L., Suyemoto, M. M., Thakur, S., Jacob, M., & Borst, L. B. (2023, August 8). MICROBIOLOGY RESOURCE ANNOUNCEMENTS, Vol. 8.

By: G. Walker n, L. Harden n, M. Suyemoto n, S. Thakur n, M. Jacob n & L. Borst n

author keywords: E; coli; UPEC; canine urinary tract infection; polymicrobial infections
TL;DR: The draft genome sequences of 12 UPEC co-isolated with Enterococcus spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 21, 2023

2023 journal article

Gallbladder microbiota in healthy dogs and dogs with mucocele formation

PLOS ONE, 18(2).

By: J. Gookin n, A. Hartley n, K. Aicher n, K. Mathews n, R. Cullen n, J. Cullen n, B. Callahan n, D. Stowe n ...

MeSH headings : Dogs; Animals; Gallbladder / pathology; Mucocele / veterinary; RNA, Ribosomal, 16S / genetics; Bile / microbiology; Gallbladder Diseases / veterinary; Microbiota / genetics; Bile Duct Diseases; Dog Diseases / diagnosis
TL;DR: Results of this study do not support existence of a core microbiome in the bile of healthy dogs or gallbladder mucus from dogs with mucocele formation, and document how contaminating sequences can significantly contribute to the results of sequencing analysis when performed on samples with low bacterial biomass. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 24, 2023

2023 article

Microbiome analysis of bile from apparently healthy cats and cats with suspected hepatobiliary disease

Slead, T. S., Callahan, B. J., Schreeg, M. E., Seiler, G. S., Stowe, D. M., Azcarate-Peril, M. A., … Gookin, J. L. (2023, September 13). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 9.

By: T. Slead n, B. Callahan n, M. Schreeg n, G. Seiler n, D. Stowe n, M. Azcarate-Peril*, M. Jacob n, J. Gookin n

author keywords: cholangitis; feline; gallbladder; microbiota
TL;DR: Cat bile does not harbor a core microbiota composed of bacterial taxa common to many individuals and Uncultured bacteria may contribute to pathogenesis of hepatobiliary disease in cats with bile E. coli infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 14, 2023

2023 article

Presence of Extended-Spectrum Beta-Lactamase-Producing <i>Escherichia coli</i> in Food-Producing and Companion Animals and Wildlife on Small-Holder Farms of Floreana Island, Galapagos Islands

Rhea, S., Gensler, C., Atlaw, N., Pairis-Garcia, M., Lewbart, G. A., Valentine, A., … Jacob, M. E. (2023, November 22). VECTOR-BORNE AND ZOONOTIC DISEASES, Vol. 11.

By: S. Rhea n, C. Gensler n, N. Atlaw n, M. Pairis-Garcia n, G. Lewbart n, A. Valentine n, M. Cruz*, P. Castillo* ...

author keywords: ESBL-E. coli; Galapagos Islands; conservation; antimicrobial resistance; multidrug resistance; surveillance
TL;DR: These results lend support for future routine AR monitoring activities at the livestock-wildlife interface in Galápagos to characterize potential interspecies transmission of AR bacteria and AR genes and to formulate interventions to reduce AR spread in this setting. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 29, 2024

2023 article

Refrigerated multi-dose insulin vials remain sterile through 6 months of use

Berg, A. S., Jacob, M. E., Mamo, L. B., Pluta, D. H., & Lunn, K. F. (2023, August 9). JOURNAL OF SMALL ANIMAL PRACTICE, Vol. 8.

By: A. Berg n, M. Jacob n, L. Mamo n, D. Pluta n & K. Lunn n

TL;DR: Refrigerated phenol- and metacresol-containing multi-dose insulin products carry minimal risk for iatrogenic infection through 6 months of use, regardless of alcohol swab preparation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 11, 2023

2023 journal article

Relating Antimicrobial Resistance and Virulence in Surface-Water <i>E. coli</i>

MICROORGANISMS, 11(11).

author keywords: virulence; antimicrobial resistance (AMR); surface water; commercial animal agriculture; E. coli
TL;DR: This work builds the understanding of factors controlling AMR dissemination through the environment and potential health risks by comparing virulence gene prevalence between isolates resistant and susceptible to antibiotics and comparing the prevalence of isolates from sub-watersheds with or without commercial hog operations. (via Semantic Scholar)
Source: Web Of Science
Added: December 18, 2023

2022 journal article

A Platelet-Rich Plasma-Derived Biologic Clears Staphylococcus aureus Biofilms While Mitigating Cartilage Degeneration and Joint Inflammation in a Clinically Relevant Large Animal Infectious Arthritis Model

Frontiers in Cellular and Infection Microbiology, 12.

By: J. Gilbertie n, T. Schaer*, J. Engiles*, G. Seiler n, B. Deddens n, A. Schubert n, M. Jacob n, D. Stefanovski* ...

author keywords: infectious arthritis; S; aureus; biofilm; antimicrobial; platelets; cartilage; synovium; synovial fluid
MeSH headings : Amikacin; Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Arthritis, Infectious / drug therapy; Biofilms; Biological Products; Disease Models, Animal; Horses; Inflammation; Platelet-Rich Plasma; Staphylococcal Infections / drug therapy; Staphylococcal Infections / veterinary; Staphylococcus aureus
TL;DR: The results demonstrate the in vivo efficacy of AMK+BIO-PLY and represents a new approach to restore and potentiate antimicrobial activity against synovial fluid biofilms. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: June 20, 2022

2022 journal article

A watershed study assessing effects of commercial hog operations on microbial water quality in North Carolina, USA

SCIENCE OF THE TOTAL ENVIRONMENT, 838.

author keywords: Watershed; Surface water; Fecal indicator bacteria; Antimicrobial resistance; Microbial source tracking; Commercial hog operations
MeSH headings : Animals; Anti-Infective Agents; Bacteria; Environmental Monitoring / methods; Escherichia coli; Feces / microbiology; North Carolina; Swine; Water Microbiology; Water Pollution; Water Quality
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 15, 2022

2022 journal article

Detection and molecular characterization of Salmonella species on US goat operations

PREVENTIVE VETERINARY MEDICINE, 208.

By: S. Hempstead n, C. Gensler n, S. Keelara n, M. Brennan*, N. Urie*, A. Wiedenheft*, K. Marshall*, B. Morningstar-Shaw* ...

author keywords: Goat; Salmonella; Antimicrobial resistance (AMR)
MeSH headings : United States / epidemiology; Animals; Humans; Goats; Gentian Violet; Salmonella; Anti-Bacterial Agents / therapeutic use; Tetracycline; Anti-Infective Agents / pharmacology; Drug Resistance, Bacterial; Microbial Sensitivity Tests / veterinary; Drug Resistance, Multiple, Bacterial / genetics
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: December 19, 2022

2022 article

Detection of Escherichia coli and Enterococcus spp. in dogs with polymicrobial urinary tract infections: A 5-year retrospective study

Walker, G. K., Yustyniuk, V., Shamoun, J., Jacob, M. E., Correa, M., Vaden, S. L., & Borst, L. B. (2022, May 27). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 5.

By: G. Walker n, V. Yustyniuk*, J. Shamoun n, M. Jacob n, M. Correa n, S. Vaden n, L. Borst n

author keywords: antibiotics; bacteriuria; cystitis; urine culture
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteriuria / drug therapy; Bacteriuria / epidemiology; Bacteriuria / veterinary; Dog Diseases / drug therapy; Dogs; Doxycycline; Enterococcus; Escherichia coli; Escherichia coli Infections / drug therapy; Escherichia coli Infections / veterinary; Gentamicins; Humans; Retrospective Studies; Urinary Tract Infections / drug therapy; Urinary Tract Infections / epidemiology; Urinary Tract Infections / veterinary
TL;DR: Polymicrobial UTI had more frequent adverse clinical outcomes for dogs and was more prevalent than monomicrobial UTI, and isolate antimicrobial resistance was more frequently resistant to doxycycline and gentamicin. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 6, 2022

2022 review

Surveillance of antimicrobial resistance in veterinary medicine in the United States: Current efforts, challenges, and opportunities

[Review of ]. FRONTIERS IN VETERINARY SCIENCE, 9.

author keywords: surveillance; veterinary medicine; data sharing; antimicrobial stewardship; animal health; antimicrobial resistance (AMR)
TL;DR: The challenges and opportunities of using data from veterinary diagnostic laboratories to build a comprehensive AMR surveillance program that will support stewardship efforts and help control AMR in both humans and animals are discussed. (via Semantic Scholar)
Source: Web Of Science
Added: January 23, 2023

2021 journal article

Comparative Genomics of Atypical Enteropathogenic Escherichia coli from Kittens and Children Identifies Bacterial Factors Associated with Virulence in Kittens

INFECTION AND IMMUNITY, 89(3).

By: V. Watson n, T. Hazen*, D. Rasko*, M. Jacob n, J. Elfenbein n, S. Stauffer n, J. Gookin n

author keywords: enteropathogenic E. coli; EPEC; animal model; phylogenetic analysis
MeSH headings : Adolescent; Animals; Cats / genetics; Child; Child, Preschool; Enteropathogenic Escherichia coli / genetics; Escherichia coli Infections / genetics; Escherichia coli Infections / microbiology; Escherichia coli Proteins / genetics; Female; Genetic Variation; Genomics; Humans; Infant; Infant, Newborn; Male; Serogroup; Serotyping; Virulence / genetics
TL;DR: Kittens are identified as a host for aEPEC where intestinal epithelial colonization was associated with diarrheal disease and death and may provide a needed comparative animal model for the study of aEP EC pathogenesis. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 15, 2021

2021 journal article

Comparison of the Intestinal Pharmacokinetics of Two Different Florfenicol Dosing Regimens and Its Impact on the Prevalence and Phenotypic Resistance of E. coli and Enterococcus over Time

MICROORGANISMS, 9(9).

By: J. Halleran n, R. Minch n, H. Slyvester n, M. Jacob n, T. Prange n, R. Baynes n, D. Foster n

author keywords: antimicrobials resistance; cattle; gastrointestinal pharmacokinetics
TL;DR: There was no significant difference noted between dosing groups in proportion or persistence of phenotypically resistant bacterial isolates; however, the percent of resistant isolates was high throughout the study period. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 12, 2021

2021 journal article

Effects of danofloxacin dosing regimen on gastrointestinal pharmacokinetics and fecal microbiome in steers

SCIENTIFIC REPORTS, 11(1).

By: J. Halleran n, B. Callahan n, M. Jacob n, H. Sylvester n, T. Prange n, M. Papich n, D. Foster n

MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Cattle; Enterococcus / drug effects; Escherichia coli / drug effects; Fluoroquinolones / pharmacology; Gastrointestinal Microbiome / drug effects; Gastrointestinal Tract / drug effects; Gastrointestinal Tract / microbiology; Male
TL;DR: Danofloxacin treatment consistently resulted in the Euryarchaeota phyla decreasing over time, specifically due to a decrease in Methanobrevibacter, and although microbiome differences were minor between dosing groups, the low dose group had a higher number of isolates with MIC values high enough to cause clinically relevant resistance. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 26, 2021

2021 journal article

Factors associated with clinical interpretation of tracheal wash fluid from dogs with respiratory disease: 281 cases (2012-2017)

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(2), 1073–1079.

By: A. Graham n, K. Tefft n, D. Stowe n, M. Jacob n, J. Robertson n & E. Hawkins n

author keywords: aerobic culture; antibiotics; endotracheal; transtracheal
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteria; Dog Diseases / diagnosis; Dogs; Respiratory Tract Diseases / diagnosis; Respiratory Tract Diseases / veterinary; Retrospective Studies; Trachea
TL;DR: Endotracheal wash fluid, in particular, should be screened for gross mucus or turbidity to maximize the likelihood of an adequate specimen, while presence of bacteria on cytology was a good predictor of any growth, while their absence was aGood predictor of the absence of growth of 1+ or more. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 8, 2021

2021 journal article

Genomics accurately predicts antimicrobial resistance in Staphylococcus pseudintermedius collected as part of Vet-LIRN resistance monitoring

VETERINARY MICROBIOLOGY, 254.

By: G. Tyson*, O. Ceric*, J. Guag*, S. Nemser*, S. Borenstein*, D. Slavic*, S. Lippert*, R. McDowell* ...

author keywords: Staphylococcus pseudintermedius; Antimicrobial resistance; Genomics
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Canada; Dog Diseases / microbiology; Dogs / microbiology; Drug Resistance, Bacterial / genetics; Epidemiological Monitoring / veterinary; Genomics / methods; Genomics / standards; Genotype; Microbial Sensitivity Tests; Phenotype; Phylogeny; Reproducibility of Results; Staphylococcal Infections / microbiology; Staphylococcal Infections / veterinary; Staphylococcus / drug effects; Staphylococcus / genetics; Staphylococcus / isolation & purification; United States; Whole Genome Sequencing
TL;DR: The results show the value in using WGS to assess antimicrobial resistance in veterinary pathogens and to reveal putative new mechanisms of resistance, as well as identifying a novel rpoB mutation likely encoding rifampin resistance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 19, 2021

2021 journal article

Impact of the COVID-19 pandemic on the surveillance, prevention and control of antimicrobial resistance: a global survey

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 76(11), 3045–3058.

By: S. Tomczyk*, A. Taylor*, A. Brown*, M. Kraker*, A. El-Saed*, M. Alshamrani*, R. Hendriksen*, M. Jacob n ...

MeSH headings : Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Anti-Infective Agents; COVID-19; Drug Resistance, Bacterial; Humans; Pandemics / prevention & control; SARS-CoV-2; Surveys and Questionnaires
Sources: Web Of Science, NC State University Libraries
Added: January 18, 2022

2021 journal article

Patterns of antimicrobial drug use in veterinary primary care and specialty practice: A 6-year multi-institution study

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(3), 1496–1508.

By: R. Goggs*, J. Menard*, C. Altier*, K. Cummings*, M. Jacob n, D. Lalonde-Paul*, M. Papich n, K. Norman* ...

author keywords: antibiotic; antimicrobial drug; antimicrobial prescribing practices; antimicrobial prescription
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Anti-Infective Agents / therapeutic use; Cat Diseases / drug therapy; Cats; Dog Diseases / drug therapy; Dogs; Drug Prescriptions / veterinary; Pharmaceutical Preparations; Primary Health Care; Retrospective Studies
TL;DR: To quantify companion animal AMD prescribing in primary care and specialty practice across 3 academic veterinary hospitals with particular focus on third‐generation cephalosporins, fluoroquinolones, and carbapenems, a retrospective study is conducted. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 5, 2021

2020 journal article

Clostridioides difficile carriage in animals and the associated changes in the host fecal microbiota

ANAEROBE, 66.

By: R. Thanissery n, M. McLaren n, A. Rivera n, A. Reed n, N. Betrapally n, T. Burdette n, J. Winston n, M. Jacob n, B. Callahan n, C. Theriot n

author keywords: C. difficile; C. hiranonis; Microbiome; Ribotype; Antibiotic resistance; Animal; Canine; Equine; Feline
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Toxins / genetics; Bacterial Toxins / metabolism; Bacterial Typing Techniques; Cats; Chlorocebus aethiops; Clostridioides difficile / classification; Clostridioides difficile / drug effects; Clostridioides difficile / physiology; Clostridium Infections / epidemiology; Clostridium Infections / microbiology; Clostridium Infections / veterinary; Coculture Techniques; Dogs; Feces / microbiology; Female; Gastrointestinal Microbiome; Horses; Hospitals, Animal; Host-Pathogen Interactions; Male; Microbial Interactions; Microbial Sensitivity Tests; North Carolina; Polymerase Chain Reaction; Prevalence; RNA, Ribosomal, 16S; Ribotyping; Risk Factors; Tertiary Healthcare; Vero Cells
TL;DR: Experimental results showed a clear antagonistic relationship between the two strains in vitro, suggesting that commensal Clostridia might play a role in colonization resistance against C. difficile in different hosts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 11, 2021

2020 journal article

Comprehensive phenotypic and genotypic characterization and comparison of virulence, biofilm, and antimicrobial resistance in urinary Escherichia coli isolated from canines

VETERINARY MICROBIOLOGY, 249.

By: J. Gilbertie n, G. Levent*, K. Norman*, J. Vinasco*, H. Scott* & M. Jacob n

author keywords: Biofilm; Urinary tract infections; Canine; Uropathogenic; Escherichia coli; Antimicrobial resistance
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Dog Diseases / microbiology; Dogs; Drug Resistance, Bacterial; Escherichia coli Infections / microbiology; Escherichia coli Infections / veterinary; Genotype; Microbial Sensitivity Tests; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary; Uropathogenic Escherichia coli / classification; Uropathogenic Escherichia coli / drug effects; Uropathogenic Escherichia coli / genetics; Virulence Factors / genetics
TL;DR: UPECs isolated from clinical cases of canine UTIs show a broad negative association between antimicrobial resistance and biofilm formation, and this observation is supported both by phenotypic and genotypic endpoints. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: November 9, 2020

2020 journal article

Draft Genome Sequence of Staphylococcus pseudintermedius Strain 13-13613, Isolated from a Case of Canine Pyoderma

MICROBIOLOGY RESOURCE ANNOUNCEMENTS, 9(7).

By: I. Eichhorn*, A. Luebke-Becker, A. Lapschies*, M. Jacob n, W. Baeumer & M. Fulde*

TL;DR: The draft genome sequence of Staphylococcus pseudintermedius strain 13-13613, isolated from a case of canine pyoderma, contains 2,533,486 bp in 570 contigs. (via Semantic Scholar)
Source: Web Of Science
Added: March 10, 2020

2020 journal article

Optimizing a Screening Protocol for Potential Extended-Spectrum beta-Lactamase Escherichia coli on MacConkey Agar for Use in a Global Surveillance Program

JOURNAL OF CLINICAL MICROBIOLOGY, 58(9).

By: M. Jacob n, S. Keelara n, A. Aidara-Kane*, J. Alvarez* & P. Fedorka-Cray n

author keywords: ESBL; Escherichia coli; MacConkey agar; global surveillance
MeSH headings : Agar; Anti-Bacterial Agents / pharmacology; Escherichia coli; Escherichia coli Infections / epidemiology; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Reproducibility of Results; beta-Lactamases
TL;DR: The quality and reproducibility of MacConkey agar varied by manufacturer, which suggests that a single manufacturer and medium type should be selected for global monitoring efforts so that training and interpretation can be standardized. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 26, 2020

2020 journal article

Platelet-rich plasma lysate displays antibiofilm properties and restores antimicrobial activity against synovial fluid biofilms in vitro

JOURNAL OF ORTHOPAEDIC RESEARCH, 38(6), 1365–1374.

By: J. Gilbertie n, T. Schaer*, A. Schubert n, M. Jacob n, S. Menegatti n, R. Lavoie n, L. Schnabel n

author keywords: biofilms; equine model; infectious arthritis; platelet-rich plasma; Staphylococcus aureus
MeSH headings : Aminoglycosides / pharmacology; Animals; Anti-Bacterial Agents / pharmacology; Arthritis, Infectious / drug therapy; Biofilms / drug effects; Female; Horses; Male; Molecular Weight; Platelet-Rich Plasma; Synovial Fluid / microbiology
TL;DR: Overall, PRP‐L exhibited synergism with amikacin against aminoglycoside tolerant biofilm aggregates with greater activity against gram‐positive bacteria, which could lead to a decrease in morbidity and mortality associated with infectious arthritis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: January 27, 2020

2020 journal article

Sterility and concentration of liposomal bupivacaine single-use vial when used in a multiple-dose manner

VETERINARY SURGERY, 49(4), 772–777.

By: A. Carlson n, E. Nixon n, M. Jacob n & K. Messenger n

MeSH headings : Anesthesia, Local / methods; Anesthesia, Local / veterinary; Anesthetics, Local / analysis; Anesthetics, Local / therapeutic use; Bupivacaine / analysis; Bupivacaine / therapeutic use; Drug Contamination; Drug Storage
TL;DR: Single-use liposomal bupivacaine liposome injectable suspension used in a multiple-dose fashion for 5 days yielded no bacterial growth and remained sterile for 5 days when aseptic technique was used. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 27, 2020

2019 journal article

Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers

PLOS ONE, 14(10).

MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacokinetics; Cattle; Cattle Diseases / drug therapy; Cattle Diseases / microbiology; Cephalosporins / administration & dosage; Cephalosporins / chemistry; Cephalosporins / pharmacokinetics; Drug Resistance, Bacterial; Escherichia coli / classification; Escherichia coli / drug effects; Escherichia coli / genetics; Feces / microbiology; Microbial Sensitivity Tests; Microbiota; RNA, Ribosomal, 16S / genetics
TL;DR: CCFA leads to prolonged, low intestinal drug concentrations, and is associated with decreased E. coli concentration, an increased MIC of ceftiofur in E. Escherichia coli at specific time points, and shifts in the fecal microbiota. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 1, 2020

2019 journal article

Enhancing the one health initiative by using whole genome sequencing to monitor antimicrobial resistance of animal pathogens: Vet-LIRN collaborative project with veterinary diagnostic laboratories in United States and Canada

BMC VETERINARY RESEARCH, 15.

By: O. Ceric*, G. Tyson*, L. Goodman*, P. Mitchell*, Y. Zhang*, M. Prarat*, J. Cui*, L. Peak* ...

author keywords: Antimicrobial resistance; Surveillance; One health; Whole-genome sequencing
MeSH headings : Animals; Bacteria / drug effects; Bacteria / genetics; Bacterial Infections / epidemiology; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Canada / epidemiology; Laboratories / standards; One Health; United States / epidemiology; Veterinary Medicine / organization & administration; Whole Genome Sequencing
TL;DR: The finding of some highly resistant bacteria from companion animals, and the observation of isolates related to those isolated from humans demonstrates the public health significance of incorporating companion animal data into surveillance systems. (via Semantic Scholar)
Source: Web Of Science
Added: May 28, 2019

2019 journal article

Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections

PLOS ONE, 14(8).

MeSH headings : Animals; Arthritis / microbiology; Arthritis / pathology; Biofilms / growth & development; Disease Models, Animal; Horses; Humans; Staphylococcal Infections / microbiology; Staphylococcal Infections / pathology; Staphylococcus aureus / physiology; Swine; Synovial Fluid / microbiology
TL;DR: Staphylococcus aureus and other bacterial pathogens adapt the same biofilm aggregate phenotype with significant antimicrobial tolerance in both equine and porcine synovial fluid, analogous to human synovIAL fluid, to identify novel drug targets for treatment of prevention of these difficult to treat infectious diseases. (via Semantic Scholar)
Source: Web Of Science
Added: September 30, 2019

2019 journal article

Multi-locus DNA sequence analysis, antifungal agent susceptibility, and fungal keratitis outcome in horses from Southeastern United States

PLOS ONE, 14(3), e0214214.

By: M. Cullen n, M. Jacob n, V. Cornish n, I. VanderSchel n, H. Cotter n, M. Cubeta n, I. Carbone n, B. Gilger n

Ed(s): O. Kniemeyer

MeSH headings : Animals; Antifungal Agents / pharmacology; Eye Infections, Fungal / drug therapy; Eye Infections, Fungal / microbiology; Eye Infections, Fungal / veterinary; Horse Diseases / drug therapy; Horse Diseases / microbiology; Horses; Keratitis / drug therapy; Keratitis / microbiology; Keratitis / veterinary; Southeastern United States; Species Specificity; Thiabendazole / pharmacology
TL;DR: The results of this study suggest that treatment of equine FK with antifungal agents requires accurate fungal species identification, and demonstrate the importance of fungal identification to the species rather than genus level. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: April 15, 2019

2018 journal article

Agreement between Parallel Canine Blood and Urine Cultures: Is Urine Culture the Poor Man's Blood Culture?

JOURNAL OF CLINICAL MICROBIOLOGY, 56(9).

By: N. Barash n, A. Birkenheuer n, S. Vaden n & M. Jacob n

author keywords: blood culture; bloodstream infections; concordance; dogs; urine culture
MeSH headings : Animals; Bacteremia / diagnosis; Bacteremia / veterinary; Bacteria / growth & development; Bacteria / isolation & purification; Bacteriological Techniques / veterinary; Blood Culture / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / urine; Dogs; Retrospective Studies; Sensitivity and Specificity; Urinalysis / veterinary; Urinary Tract Infections / diagnosis; Urinary Tract Infections / veterinary
TL;DR: It is found that urine culture is neither a substitute nor a screen for blood culture, and should be performed in any potentially septic animal, especially those that are considered immunosuppressed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: October 19, 2018

2018 journal article

Characteristics of Dogs with Biofilm-Forming Escherichia Coli Urinary Tract Infections

JOURNAL OF VETERINARY INTERNAL MEDICINE, 32(5), 1645–1651.

By: Z. Kern n, M. Jacob n, J. Gilbertie n, S. Vaden n & S. Lyle n

author keywords: chronic urinary tract infection; crystal violet; multidrug resistance; symptomatic urinary tract infection
MeSH headings : Animals; Biofilms / growth & development; Cross-Sectional Studies; Dog Diseases / microbiology; Dogs; Drug Resistance, Multiple, Bacterial; Escherichia coli / physiology; Escherichia coli Infections / microbiology; Escherichia coli Infections / veterinary; Female; Male; Retrospective Studies; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary
TL;DR: The potential for biofilm formation should be considered whenever E. coli UTI is diagnosed and the association of antibiotic resistance and biofilm potential may affect treatment of UTIs, but additional investigation is warranted. (via Semantic Scholar)
Source: Web Of Science
Added: November 5, 2018

2018 article

Diluted sodium hypochlorite (bleach) in dogs: antiseptic efficacy, local tolerability and in vitro effect on skin barrier function and inflammation

Banovic, F., Olivry, T., Baumer, W., Paps, J., Stahl, J., Rogers, A., & Jacob, M. (2018, February). VETERINARY DERMATOLOGY, Vol. 29.

By: F. Banovic n, T. Olivry n, W. Baumer n, J. Paps n, J. Stahl*, A. Rogers n, M. Jacob n

Contributors: F. Banovic n, T. Olivry n, W. Bäumer n, J. Paps n, J. Stahl*, A. Rogers n, M. Jacob n

MeSH headings : Administration, Cutaneous; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / pharmacology; Anti-Infective Agents, Local / administration & dosage; Anti-Infective Agents, Local / pharmacology; Cell Survival / drug effects; Dogs; Inflammation / drug therapy; Keratinocytes / drug effects; Male; Skin / drug effects; Sodium Hypochlorite / administration & dosage; Sodium Hypochlorite / pharmacology
TL;DR: The results indicate that a topical diluted bleach solution, at either 0.05 or 0.005% hypochlorite concentrations, is a well-tolerated antiseptic that also exhibits anti-inflammatory properties. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2018 journal article

Dosing Regimen of Enrofloxacin Impacts Intestinal Pharmacokinetics and the Fecal Microbiota in Steers

Frontiers in Microbiology, 9.

By: K. Ferguson n, M. Jacob n, C. Theriot n, B. Callahan n, T. Prange n, M. Papich n, D. Foster n

author keywords: antimicrobial resistance; fluoroquinolone; cattle; microbiome; pharmacokinetics
TL;DR: Both dosing regimens of enrofloxacin achieve high concentrations in the intestinal lumen, and the rapid elimination mitigates long-term impacts on fecal E. coli resistance and the microbiota. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: October 16, 2018

2018 journal article

Efficacy of vaporized hydrogen peroxide for repeated sterilization of a single‐use single‐incision laparoscopic surgery port

Veterinary Surgery, 48(S1), O59–O65.

By: V. Scharf n, B. Dent n, M. Jacob n & B. Moore n

MeSH headings : Aerosols; Animals; Anti-Infective Agents, Local / pharmacology; Decontamination; Humans; Hydrogen Peroxide / pharmacology; Laparoscopy / instrumentation; Laparoscopy / veterinary; Prospective Studies; Sterilization / methods
TL;DR: It is suggested that a single-use single-incision laparoscopic port and its associated components can be effectively sterilized after multiple simulated uses by using VHP. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref
Added: June 17, 2019

2018 journal article

Factors associated with strongyle infection in goats at the individual and farm level

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 253(7), 907–917.

By: H. Sylvester, E. Griffith*, M. Jacob* & D. Foster*

MeSH headings : Animals; Cross-Sectional Studies; Female; Goat Diseases / epidemiology; Goat Diseases / parasitology; Goats; Male; North Carolina / epidemiology; Parasite Egg Count / veterinary; Prevalence; Strongylida Infections / epidemiology; Strongylida Infections / veterinary; Strongyloides / isolation & purification
TL;DR: The finding that farms with no history of anthelmintic use had the lowest mean FECs suggested that a focus on preventative measures could reduce the need for anthel mintic drugs and, by extension, lessen the opportunity for the development of anesthetic resistance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 16, 2018

2018 journal article

Gram-negative multi-drug resistant bacteria influence survival to discharge for horses with septic synovial structures: 206 Cases (2010-2015)

VETERINARY MICROBIOLOGY, 226, 64–73.

By: J. Gilbertie n, L. Schnabel n, D. Stefanovski, D. Kelly, M. Jacob n & T. Schaer

author keywords: Septic synovitis; Infectious arthritis; Equine; Multi-drug resistance (MDR); Fluoroquinolones; Gram-negative bacteria
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Arthritis, Infectious / microbiology; Arthritis, Infectious / veterinary; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae / drug effects; Enterobacteriaceae Infections / mortality; Enterobacteriaceae Infections / veterinary; Gram-Negative Bacteria / drug effects; Gram-Negative Bacterial Infections / mortality; Gram-Negative Bacterial Infections / veterinary; Horse Diseases / microbiology; Horse Diseases / mortality; Horses; Hospitals, Animal; Microbial Sensitivity Tests; Patient Discharge / statistics & numerical data; Pseudomonas aeruginosa / drug effects; Staphylococcus / drug effects; Synovial Fluid / cytology; Synovial Fluid / microbiology; Synovitis / microbiology; Synovitis / veterinary
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: December 3, 2018

2018 journal article

Microbial integrity of preservative-free alfaxalone in a multiple-use system for two storage conditions and three handling techniques

AMERICAN JOURNAL OF VETERINARY RESEARCH, 79(7), 704–710.

By: M. Whitehead*, C. Vanetten*, M. Jacob* & T. Harrison*

MeSH headings : Anesthetics / administration & dosage; Animals; Colony Count, Microbial; Drug Contamination; Drug Packaging; Drug Storage; North Carolina; Pregnanediones / administration & dosage; Quality Control; Refrigeration; Sterilization; Temperature; Time Factors; United States; United States Food and Drug Administration; Universities
TL;DR: Alfaxalone is supported for 7 days when refrigerated and handled with a single puncture of the stopper by use of a protected port (closed system transfer device or nonclosed dispensing pin) and would appear to be a practical alternative for an injectable anesthetic. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Association of Atypical Enteropathogenic Escherichia coli with Diarrhea and Related Mortality in Kittens

Journal of Clinical Microbiology, 55(9), 2719–2735.

By: V. Watson n, M. Jacob n, J. Flowers n, S. Strong*, C. DebRoy* & J. Gookin n

Ed(s): B. Fenwick

author keywords: Escherichia coli enterocyte attaching and effacing (eae) gene; EPEC; animal models; histopathology; cat
MeSH headings : Animals; Cat Diseases / microbiology; Cats; Colon / microbiology; Diarrhea / microbiology; Diarrhea / mortality; Diarrhea / veterinary; Disease Models, Animal; Enteropathogenic Escherichia coli / genetics; Enteropathogenic Escherichia coli / isolation & purification; Enteropathogenic Escherichia coli / pathogenicity; Escherichia coli Infections / microbiology; Escherichia coli Infections / mortality; Escherichia coli Infections / veterinary; Intestine, Small / microbiology; Multiplex Polymerase Chain Reaction; Parenteral Nutrition / methods; Virulence / genetics
TL;DR: Findings identify aEPEC to be prevalent in kittens and a significant primary or contributing cause of intestinal inflammation, diarrhea, dehydration, and associated mortality in kittens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2017 journal article

Creation and Evaluation of New Porcine Model for Investigation of Treatments of Surgical Site Infection

TISSUE ENGINEERING PART C-METHODS, 23(11), 795–803.

By: M. Mohiti-Asli n, M. Risselada n, M. Jacob n, B. Pourdeyhimi n & E. Loboa n

author keywords: surgical site infection; porcine model; antimicrobial scaffold; silver; electrospinning; MRSA
MeSH headings : Animals; Anti-Infective Agents / pharmacology; Anti-Infective Agents / therapeutic use; Disease Models, Animal; Female; Methicillin-Resistant Staphylococcus aureus / drug effects; Nanofibers / chemistry; Nanofibers / ultrastructure; Polyesters / chemistry; Porosity; Surgical Wound Infection / drug therapy; Surgical Wound Infection / microbiology; Surgical Wound Infection / pathology; Sus scrofa; Tissue Scaffolds / chemistry
TL;DR: A porcine full-thickness incision model to investigate SSI caused by methicillin-resistant Staphylococcus aureus is developed, and the potential of silver releasing nanofibrous scaffolds for treatment/prevention of SSI is confirmed, and a new porcines model is introduced for in vivo evaluation of additional SSI treatment approaches are introduced. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Efficacy of an Escherichia coli O157:H7 SRP Vaccine in Orally Challenged Goats and Strain Persistence Over Time

FOODBORNE PATHOGENS AND DISEASE, 14(3), 160–166.

By: J. Swift n, D. Foster n, A. Rogers n, H. Sylvester n, E. Griffith n & M. Jacob n

author keywords: Shiga toxin-producing E. coli; goats; livestock exhibition; vaccination
MeSH headings : Administration, Oral; Animals; Bacterial Outer Membrane Proteins / immunology; Electrophoresis, Gel, Pulsed-Field; Escherichia coli Infections / prevention & control; Escherichia coli Infections / veterinary; Escherichia coli O157 / immunology; Escherichia coli Proteins / genetics; Escherichia coli Proteins / immunology; Escherichia coli Vaccines / immunology; Feces / microbiology; Food Contamination / prevention & control; Food Microbiology; Goat Diseases / microbiology; Goat Diseases / prevention & control; Goats / immunology; Goats / microbiology; Male; Milk / microbiology; Porins / immunology; Receptors, Cell Surface / immunology; Red Meat / microbiology; Vaccination / veterinary
TL;DR: Further work is needed to evaluate cost-effective intervention strategies that reliably reduce E. coli O157:H7 shedding in goats, particularly those that may reduce the risk of transmission at public events, including petting zoos and fairs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Establishing a canine superficial pyoderma model

Journal of Applied Microbiology, 122(2), 331–337.

author keywords: canine; infection; pulsed-field gel electrophoresis; pyoderma; Staphylococcus pseudintermedius; veterinary
MeSH headings : Animals; Dermatitis, Atopic / complications; Dermatitis, Atopic / veterinary; Disease Models, Animal; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Female; Male; Pyoderma / microbiology; Pyoderma / pathology; Pyoderma / veterinary; Staphylococcal Skin Infections / microbiology; Staphylococcal Skin Infections / pathology; Staphylococcal Skin Infections / veterinary; Staphylococcus / classification; Staphylococcus / isolation & purification; Staphylococcus / physiology
TL;DR: A dog model of pyoderma is established that closely mimics the natural disease and new treatment strategies are investigated, complicated by increasing antimicrobial resistance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Crossref
Added: July 27, 2019

2016 journal article

Comparison of lipopolysaccharides and soluble CD14 measurement between clinically endotoxaemic and nonendotoxaemic horses

Equine Veterinary Journal, 49(2), 155–159.

Contributors: J. Fogle n, M. Jacob n, A. Blikslager n, A. Edwards n, B. Wagner*, K. Dean n, C. Fogle n

author keywords: horse; soluble CD14; endotoxin; sepsis; inflammation; colic
MeSH headings : Animals; Biomarkers / blood; Endotoxemia / blood; Endotoxemia / veterinary; Horse Diseases / blood; Horse Diseases / diagnosis; Horses; Lipopolysaccharide Receptors / blood; Lipopolysaccharides
TL;DR: It is suggested that sCD14 and LPS were poor predictors of clinical endotoxaemia for the horses in this study, and further investigation is warranted to assess the utility of s CD14 measurement as a clinically useful biomarker to identify endotox aemia in horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

Diagnostic accuracy of a rapid immunoassay for point-of-care detection of urinary tract infection in dogs

AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(2), 162–166.

By: M. Jacob*, M. Crowell, M. Fauls*, E. Griffith* & K. Ferris*

MeSH headings : Animals; Bacterial Infections / diagnosis; Bacterial Infections / veterinary; Dog Diseases / diagnosis; Dogs; Immunoassay / methods; Immunoassay / veterinary; Point-of-Care Systems; Sensitivity and Specificity; Urinary Tract Infections / diagnosis; Urinary Tract Infections / veterinary
TL;DR: The RIA test evaluated in this study accurately detected UTI of dogs, compared with detection with the criterion-referenced bacterial culture method, and could allow clinicians to diagnose UTI at the time of a patient visit and provide information useful for immediately initiating empirical antimicrobial treatment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Effect of high-pressure processing of bovine colostrum on immunoglobulin G concentration, pathogens, viscosity, and transfer of passive immunity to calves

JOURNAL OF DAIRY SCIENCE, 99(11), 8575–8588.

By: D. Foster n, K. Poulsen*, H. Sylvester n, M. Jacob n, K. Casulli n & B. Farkas n

author keywords: high-pressure processing; bovine colostrum; pasteurization; Mycobacterium avium ssp paratuberculosis
MeSH headings : Animals; Animals, Newborn; Cattle; Colostrum / immunology; Escherichia coli / immunology; Female; Immunoglobulin G / blood; Pilot Projects; Staphylococcus aureus / immunology; Viscosity
TL;DR: High-pressure processing of bovine colostrum maintains an acceptable IgG level while decreasing bacterial and viral counts, and is suggested to be appropriate for on-farm use. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

Feeding wet distillers grains plus solubles with and without a direct-fed microbial to determine performance, carcass characteristics, and fecal shedding of Escherichia coli O157:H7 in feedlot heifers

JOURNAL OF ANIMAL SCIENCE, 94(1), 297–305.

By: B. Wilson*, B. Holland*, D. Step*, M. Jacob*, D. VanOverbeke*, C. Richards*, T. Nagaraja*, C. Krehbiel*

author keywords: beef cattle; direct-fed microbials; Lactobacillus acidophilus; Propionibacterium freudenreichii; wet distillers grains plus solubles
MeSH headings : Animal Feed / analysis; Animals; Bacterial Shedding / drug effects; Bacterial Shedding / physiology; Body Weight; Cattle; Diet / veterinary; Escherichia coli O157 / drug effects; Escherichia coli O157 / physiology; Feces / microbiology; Female; Lactobacillus acidophilus / physiology; Probiotics; Propionibacterium / physiology; Zea mays
TL;DR: Feeding 30% WDGS to feedlot heifers improved animal performance compared to the DRC-based control diet and the incidence of O157:H7 throughout the experiment was low, with only 18 positive samples across all sampling periods. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Isolation and characterization of atypical Listeria monocytogenes associated with a canine urinary tract infection

Journal of Veterinary Diagnostic Investigation, 28(5), 604–607.

By: J. Palerme n, P. Pan n, C. Parsons n, S. Kathariou n, T. Ward n & M. Jacob n

author keywords: Canine listeriosis; canine urinary tract infection; Listeria monocytogenes
MeSH headings : Animals; Diabetes Mellitus, Type 2 / complications; Diabetes Mellitus, Type 2 / veterinary; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Listeria monocytogenes / isolation & purification; Listeriosis / complications; Listeriosis / microbiology; Listeriosis / veterinary; Male; Urinary Tract Infections / complications; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary
TL;DR: The serotype of the L. monocytogenes isolate was determined to be 1/2a (3a), and a nucleotide substitution was detected at residue 145 in the promoter prfA region, within the critical helix-turn-helix motif of PrfA. (via Semantic Scholar)
Sources: Web Of Science, Crossref
Added: August 6, 2018

2016 journal article

Listeria monocytogenes septicemia in an immunocompromised dog

VETERINARY CLINICAL PATHOLOGY, 45(2), 254–259.

By: J. Pritchard n, M. Jacob n, T. Ward*, C. Parsons n, S. Kathariou n & M. Wood*

author keywords: Blood culture; canine; food contamination; infection; sepsis
TL;DR: An 11-year-old, male castrated, Boston Terrier was presented to the North Carolina State University College of Veterinary Medicine Small Animal Emergency Service with a 2-day history of progressive ataxia, left-sided head tilt, and anorexia, and was positive for Listeria monocytogenes serotype 4b (epidemic clone 1). (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Molecular confirmation of shampoo as the putative source of Pseudomonas aeruginosa-induced postgrooming furunculosis in a dog

VETERINARY DERMATOLOGY, 27(4), 320–E80.

By: H. Tham n, M. Jacob n & P. Bizikova n

TL;DR: A clinical investigation suggests a link between Pseudomonas-contaminated shampoo and development of postgrooming furunculosis, and underscores the need for hygienic management of shampoos to help limit this disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Deep pyoderma caused by Burkholderia cepacia complex associated with ciclosporin administration in dogs: a case series

VETERINARY DERMATOLOGY, 26(4), 287-+.

By: F. Banovic n, S. Koch*, D. Robson, M. Jacob n & T. Olivry n

Contributors: F. Banovic n, S. Koch*, D. Robson, M. Jacob n & T. Olivry n

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Burkholderia Infections / complications; Burkholderia Infections / drug therapy; Burkholderia Infections / pathology; Burkholderia Infections / veterinary; Burkholderia cepacia complex; Cyclosporine / adverse effects; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Immunocompromised Host; Immunosuppressive Agents / adverse effects; Male; Pyoderma / etiology; Pyoderma / pathology; Pyoderma / veterinary; Retrospective Studies; Skin / microbiology; Skin / pathology
TL;DR: Clinicians should be aware of the rare potential for Bcc-associated deep skin infections in dogs receiving oral ciclosporin and owners should be made conscious of the potential transmission risk to humans or other animals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Opinions of clinical veterinarians at a US veterinary teaching hospital regarding antimicrobial use and antimicrobial-resistant infections

Journal of the American Veterinary Medical Association, 247(8), 938–944.

By: M. Jacob*, J. Hoppin*, N. Steers*, J. Davis*, G. Davidson*, B. Hansen, K. Lunn*, K. Murphy, M. Papich*

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteria / drug effects; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Cross-Sectional Studies; Data Collection; Drug Resistance, Bacterial; Education, Veterinary; Female; Hospitals, Animal; Humans; Male; Professional Practice; Schools, Veterinary; United States; Veterinarians
TL;DR: Findings indicated that veterinarians at this teaching hospital were concerned about antimicrobial resistance, thought antimicrobials were overprescribed, and supported restricting use of certain antimicrobial classes in companion animals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Pharmacokinetics of enrofloxacin and ceftiofur in plasma, interstitial fluid, and gastrointestinal tract of calves after subcutaneous injection, and bactericidal impacts on representative enteric bacteria

Journal of Veterinary Pharmacology and Therapeutics, 39(1), 62–71.

By: D. Foster n, M. Jacob n, C. Warren n & M. Papich n

MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Cattle / blood; Cephalosporins / administration & dosage; Cephalosporins / blood; Cephalosporins / metabolism; Cephalosporins / pharmacokinetics; Drug Resistance, Bacterial; Enrofloxacin; Enterococcus faecalis / drug effects; Fluoroquinolones / administration & dosage; Fluoroquinolones / blood; Fluoroquinolones / metabolism; Fluoroquinolones / pharmacokinetics; Half-Life; Intestines / microbiology; Microbial Sensitivity Tests; Salmonella enterica / drug effects
TL;DR: Enrofloxacin and ceftiofur achieved intestinal concentrations capable of reducing intestinal bacteria, yet the short exposure of ceftIOfur in the intestine may select for resistant organisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: March 2, 2019

2015 article

Prevalence and relatedness of Escherichia coli O157:H7 strains in the feces and on the hides and carcasses of U.S. meat goats at slaughter (vol 79, pg 4154, 2013)

Applied and Environmental Microbiology, Vol. 81, pp. 462–462.

By: M. Jacob, D. Foster, A. Rogers, C. Balcomb & M. Sanderson

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Comparing Real-Time and Conventional PCR to Culture-Based Methods for Detecting and Quantifying Escherichia coli O157 in Cattle Feces

JOURNAL OF FOOD PROTECTION, 77(2), 314–319.

MeSH headings : Animals; Bacterial Shedding; Cattle; Colony Count, Microbial; DNA, Bacterial / genetics; Escherichia coli O157 / genetics; Escherichia coli O157 / isolation & purification; Escherichia coli Proteins / genetics; Feces / microbiology; Immunomagnetic Separation / methods; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / standards; Real-Time Polymerase Chain Reaction / methods; Real-Time Polymerase Chain Reaction / standards; Sensitivity and Specificity; Shiga Toxin 1 / genetics; Shiga Toxin 2 / genetics
TL;DR: It is suggested that mqPCR and conventional PCR are most useful in identifying high shedder animals and may not be an appropriate substitute to culture-based methods for detection of E. coli O157 in cattle feces. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Edwardsiella tarda and Aeromonas hydrophila isolated from diseased Southern flounder (Paralichthys lethostigma) are virulent to channel catfish and Nile tilapia

Journal of Coastal Life Medicine, 5.

By: N. Libraries

UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 22, 2019

2014 journal article

Implantation of an ultrafiltration device in the ileum and spiral colon of steers to continuously collect intestinal fluid

Research in Veterinary Science, 97(3), 611–615.

By: C. Warren, T. Prange, N. Campbell, M. Gerard, L. Martin, M. Jacob*, G. Smith*, M. Papich*, D. Foster*

author keywords: Bovine; Gastrointestinal fluid; Surgery; Ultrafiltration
MeSH headings : Animals; Body Fluids; Cattle; Colon / surgery; Ileum / surgery; Intestinal Secretions; Specimen Handling / methods; Specimen Handling / veterinary; Ultrafiltration / instrumentation
TL;DR: Use of ultrafiltration probes is a novel, consistent and humane method to repeatedly sample the gastrointestinal contents. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, ORCID
Added: March 2, 2019

2014 journal article

Vaginal Microbiota of Spayed Dogs with or without Recurrent Urinary Tract Infections

JOURNAL OF VETERINARY INTERNAL MEDICINE, 28(2), 300–304.

By: R. Hutchins*, S. Vaden n, M. Jacob n, T. Harris n, K. Bowles n, M. Wood n, C. Bailey n

author keywords: Recurrent urinary tract infection; Lactic acid-producing bacteria
MeSH headings : Animals; Dog Diseases / microbiology; Dogs / microbiology; Female; Microbiota; Ovariectomy / veterinary; Recurrence; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary; Vagina / microbiology
TL;DR: The vaginal microbiota of spayed female dogs with recurrent UTI was similar to the control population of normal, spayed male dogs and vaginal bacteria isolate from vaginal swabs obtained from each dog. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Evidence of Non-O157 Shiga Toxin-Producing Escherichia coli in the Feces of Meat Goats at a US Slaughter Plant

JOURNAL OF FOOD PROTECTION, 76(9), 1626–1629.

MeSH headings : Abattoirs; Animals; Cattle; Colony Count, Microbial; DNA, Bacterial / analysis; Disease Reservoirs / microbiology; Disease Reservoirs / veterinary; Feces / microbiology; Food Microbiology; Goats; Humans; Meat / microbiology; Multiplex Polymerase Chain Reaction; Prevalence; Serotyping; Shiga-Toxigenic Escherichia coli / classification; Shiga-Toxigenic Escherichia coli / isolation & purification; Southeastern United States
TL;DR: Goats appear to be an important reservoir for non-O157 STEC, and further work to understand the characteristics, epidemiology, and ecology of STEC in these animals is warranted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

Prevalence and Relatedness of Escherichia coli O157:H7 Strains in the Feces and on the Hides and Carcasses of US Meat Goats at Slaughter

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 79(13), 4154–4158.

MeSH headings : Animals; Cluster Analysis; Electrophoresis, Gel, Pulsed-Field / veterinary; Escherichia coli Infections / epidemiology; Escherichia coli Infections / veterinary; Escherichia coli O157 / genetics; Feces / microbiology; Food-Processing Industry / standards; Goat Diseases / epidemiology; Goat Diseases / microbiology; Goats; Meat / microbiology; Prevalence; Skin / microbiology; Southeastern United States / epidemiology; Species Specificity
TL;DR: Sixteen pulsed-field gel electrophoresis (PFGE) subtypes were identified among 49 E. coli O157:H7 isolates, some of which were present on multiple sample types or collection days. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

The Effect of an Oral Probiotic Containing Lactobacillus, Bifidobacterium, and Bacillus Species on the Vaginal Microbiota of Spayed Female Dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 27(6), 1368–1371.

By: R. Hutchins n, C. Bailey n, M. Jacob n, T. Harris n, M. Wood n, K. Saker n, S. Vaden n

author keywords: Lactic acid-producing bacteria; Recurrent urinary tract infection
MeSH headings : Animals; Bacillus / genetics; Bacillus / isolation & purification; Bifidobacterium / genetics; Bifidobacterium / isolation & purification; Dog Diseases / microbiology; Dog Diseases / prevention & control; Dogs; Female; Lactobacillus / genetics; Lactobacillus / isolation & purification; Microbiota / genetics; Probiotics / pharmacology; Sequence Analysis, DNA; Urinary Tract Infections / microbiology; Urinary Tract Infections / prevention & control; Urinary Tract Infections / veterinary; Vagina / microbiology
TL;DR: Administration of this oral probiotic supplement for a 2- or 4-week period did not increase the prevalence of vaginal LAB in dogs and Enterococcus canintestini was the most common LAB isolated from all dogs in this study, although it was not included in the probiotics supplement. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Evaluation of a Multiplex Real-Time Polymerase Chain Reaction for the Quantification of Escherichia coli O157 in Cattle Feces

FOODBORNE PATHOGENS AND DISEASE, 9(1), 79–85.

By: M. Jacob n, X. Shi*, B. An*, T. Nagaraja* & J. Bai*

MeSH headings : Animals; Bacterial Shedding; Carbohydrate Epimerases / genetics; Cattle; Cattle Diseases / diagnosis; Colony Count, Microbial; DNA Primers / genetics; DNA, Bacterial / genetics; Escherichia coli Infections / diagnosis; Escherichia coli Infections / veterinary; Escherichia coli O157 / genetics; Escherichia coli O157 / isolation & purification; Escherichia coli Proteins / genetics; Feces / microbiology; Multiplex Polymerase Chain Reaction; Real-Time Polymerase Chain Reaction; Sensitivity and Specificity; Shiga Toxin 1 / genetics; Shiga Toxin 2 / genetics; Transaminases / genetics
TL;DR: The mqPCR quantifying E. coli O157 in cattle feces using stx1, stx2, and rfbE gene targets may have use in detecting and quantifying super shedders, but is not applicable for quantification in animals shedding low concentrations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Escherichia coli O157:H7 Genetic Diversity in Bovine Fecal Samples

JOURNAL OF FOOD PROTECTION, 74(7), 1186–1188.

By: M. Jacob*, K. Almes*, X. Shi*, J. Sargeant* & T. Nagaraja*

MeSH headings : Animals; Carrier State / microbiology; Carrier State / veterinary; Cattle / microbiology; Consumer Product Safety; Disease Reservoirs / microbiology; Disease Reservoirs / veterinary; Electrophoresis, Gel, Pulsed-Field; Escherichia coli Infections / prevention & control; Escherichia coli O157 / classification; Escherichia coli O157 / genetics; Escherichia coli O157 / pathogenicity; Feces / microbiology; Food Contamination / prevention & control; Food Microbiology; Genetic Variation; Humans; Phylogeny; Prevalence
TL;DR: The results of this study suggest that determining the PFGE pattern of a single isolate from a bovine sample may not be sufficient when comparing isolates from feces, hides, or carcasses, because multiple PFGE subtypes are present. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Modeling Preharvest and Harvest Interventions for Escherichia coli O157 Contamination of Beef Cattle Carcasses

Journal of Food Protection, 74(9), 1422–1433.

By: C. Dodd*, M. Sanderson*, M. Jacob* & D. Renter*

MeSH headings : Animal Husbandry / methods; Animals; Cattle / microbiology; Colony Count, Microbial; Escherichia coli O157 / growth & development; Feces / microbiology; Food Contamination / analysis; Food Contamination / prevention & control; Food Microbiology; Humans; Models, Biological; Monte Carlo Method; Prevalence; Risk Assessment; Risk Factors; Seasons; Skin / microbiology; Stochastic Processes; Transportation
TL;DR: Results indicated that combinations of preharvest interventions may be particularly important for supplementing harvest interventions during periods of higher variability in fecal shedding prevalence (i.e., summer), and assessments of the relationships among fecal prevalence and concentration, hide contamination, and subsequent carcass contamination are needed. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2010 journal article

Animal- and Truckload-Level Associations between Escherichia coli O157:H7 in Feces and on Hides at Harvest and Contamination of Preevisceration Beef Carcasses

Journal of Food Protection, 73(6), 1030–1037.

By: M. Jacob*, D. Renter* & T. Nagaraja*

MeSH headings : Abattoirs; Animals; Cattle / microbiology; Colony Count, Microbial; Escherichia coli O157 / isolation & purification; Feces / microbiology; Food Contamination / analysis; Food Contamination / prevention & control; Food Microbiology; Humans; Logistic Models; Odds Ratio; Prevalence; Risk Factors; Skin / microbiology; Transportation
TL;DR: The results suggest that preharvest interventions for reducing E. coli O157:H7 contamination of carcasses should focus on truckload (cohort)-level and hide mitigation strategies. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2010 journal article

Effects of Feeding Elevated Concentrations of Copper and Zinc on the Antimicrobial Susceptibilities of Fecal Bacteria in Feedlot Cattle

Foodborne Pathogens and Disease, 7(6), 643–648.

MeSH headings : Animal Feed / analysis; Animal Husbandry / methods; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacology; Bacterial Typing Techniques; Cattle; Copper / administration & dosage; Copper / pharmacology; DNA, Bacterial / isolation & purification; DNA, Bacterial / metabolism; Drug Resistance, Bacterial / genetics; Enterococcus / classification; Enterococcus / drug effects; Enterococcus / genetics; Enterococcus / growth & development; Enterococcus / isolation & purification; Escherichia coli / classification; Escherichia coli / drug effects; Escherichia coli / genetics; Escherichia coli / growth & development; Escherichia coli / isolation & purification; Feces / microbiology; Female; Genes, Bacterial; Microbial Sensitivity Tests; Polymerase Chain Reaction; Random Allocation; Rectum / microbiology; Time Factors; Zinc / administration & dosage; Zinc / pharmacology
TL;DR: Feeding elevated copper and/or zinc to feedlot cattle had marginal effects on antimicrobial susceptibilities of fecal E. coli and enterococci. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2010 journal article

Inclusion of Dried or Wet Distillers' Grains at Different Levels in Diets of Feedlot Cattle Affects Fecal Shedding of Escherichia coli O157:H7

Applied and Environmental Microbiology, 76(21), 7238–7242.

By: M. Jacob*, Z. Paddock*, D. Renter*, K. Lechtenberg & T. Nagaraja*

MeSH headings : Animal Feed / microbiology; Animal Husbandry; Animals; Bacterial Shedding / physiology; Cattle / metabolism; Cattle / microbiology; Cattle / physiology; Cattle Diseases / metabolism; Cattle Diseases / microbiology; Cattle Diseases / prevention & control; Diet / veterinary; Edible Grain / microbiology; Escherichia coli Infections / microbiology; Escherichia coli Infections / prevention & control; Escherichia coli Infections / veterinary; Escherichia coli O157 / isolation & purification; Escherichia coli O157 / physiology; Feces / microbiology; Male
TL;DR: The prevalence levels of E. coli O157:H7 and the numbers of high shedders were not different between diets with 0 or 20% DG; however, cattle fed 40% DG had a higher prevalence and more high-shedder than cattle fed 0 or20% DG (P ≤ 0.05), and fecal shedding was associated with the DG inclusion level. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2010 journal article

Occurrence of tcrB, a Transferable Copper Resistance Gene, in Fecal Enterococci of Swine

Foodborne Pathogens and Disease, 7(9), 1089–1097.

By: R. Amachawadi*, N. Shelton*, M. Jacob*, X. Shi*, S. Narayanan*, L. Zurek*, S. Dritz*, J. Nelssen*, M. Tokach*, T. Nagaraja*

MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Bacterial Proteins / genetics; Copper / administration & dosage; DNA, Bacterial / analysis; Diet; Drug Resistance, Microbial / genetics; Enterococcus / genetics; Enterococcus faecalis / genetics; Enterococcus faecium / genetics; Feces / microbiology; Microbial Sensitivity Tests; Polymerase Chain Reaction; Selection, Genetic / drug effects; Swine / microbiology
TL;DR: The potential link between tcrB and antibiotic resistance genes and the propensity of enterococci to transfer tcr B to other strains raises the possibility that copper supplementation may exert selection pressure for antibiotic-resistant enterococCI. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2009 journal article

Dietary Interactions and Interventions Affecting Escherichia coli O157 Colonization and Shedding in Cattle

Foodborne Pathogens and Disease, 6(7), 785–792.

By: M. Jacob*, T. Callaway* & T. Nagaraja*

MeSH headings : Animal Feed / adverse effects; Animal Husbandry / methods; Animals; Bacterial Shedding; Cattle / microbiology; Diet / adverse effects; Diet / veterinary; Edible Grain / adverse effects; Escherichia coli Infections / microbiology; Escherichia coli Infections / prevention & control; Escherichia coli O157 / isolation & purification; Escherichia coli O157 / physiology; Feces / microbiology; Food Handling; Food Microbiology; Foodborne Diseases / prevention & control; Host-Pathogen Interactions; Humans
TL;DR: Understanding specific mechanisms, driven by diet influences, responsible for E. coli O157 shedding will aid in the development and implementation of better and practical preharvest intervention strategies. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2009 journal article

Evaluation of Feeding Dried Distiller's Grains with Solubles and Dry-Rolled Corn on the Fecal Prevalence of Escherichia coli O157:H7 and Salmonella spp. in Cattle

Foodborne Pathogens and Disease, 6(2), 145–153.

By: M. Jacob*, J. Fox*, J. Drouillard*, D. Renter* & T. Nagaraja*

MeSH headings : Animal Feed / analysis; Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Cattle / microbiology; Diet / veterinary; Escherichia coli O157 / isolation & purification; Feces / microbiology; Female; Prevalence; Random Allocation; Salmonella / isolation & purification; Solubility; Zea mays
TL;DR: Evaluation of the effect of feeding DG and dry-rolled corn, alone or in combination, on fecal prevalence of E. coli O157:H7 in finishing cattle found no association between either DG or DRC and Salmonella prevalence, contrary to previous observations. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2008 journal article

Antimicrobial Susceptibility of Foodborne Pathogens in Organic or Natural Production Systems: An Overview

Foodborne Pathogens and Disease, 5(6), 721–730.

By: M. Jacob*, J. Fox*, S. Reinstein* & T. Nagaraja*

MeSH headings : Animal Husbandry / methods; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacology; Consumer Product Safety / standards; Drug Resistance, Bacterial; Food Microbiology; Food, Organic; Marketing / economics; Marketing / methods; Meat / standards; Microbial Sensitivity Tests; Species Specificity
TL;DR: Comparing the impact of food animal production systems on the antimicrobial susceptibility of common foodborne bacterial pathogens and the literature is highly variable in terms of production type and practices and susceptibility associations, although few studies have compared truly organic and conventional practices. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2008 journal article

Effects of feeding wet corn distillers grains with solubles with or without monensin and tylosin on the prevalence and antimicrobial susceptibilities of fecal foodborne pathogenic and commensal bacteria in feedlot cattle1

Journal of Animal Science, 86(5), 1182–1190.

author keywords: antimicrobial feed additive; antimicrobial susceptibility; cattle; distillers grain; Escherichia coli O157
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena / drug effects; Animal Nutritional Physiological Phenomena / physiology; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacology; Cattle / metabolism; Cattle / microbiology; Colony Count, Microbial; Drug Resistance, Bacterial / genetics; Edible Grain; Enterococcus / drug effects; Enterococcus / growth & development; Escherichia coli / drug effects; Escherichia coli / growth & development; Escherichia coli O157 / drug effects; Escherichia coli O157 / growth & development; Feces / microbiology; Female; Food Handling / methods; Microbial Sensitivity Tests / veterinary; Monensin / administration & dosage; Monensin / pharmacology; Prevalence; Random Allocation; Salmonella / drug effects; Salmonella / growth & development; Solubility; Tylosin / administration & dosage; Tylosin / pharmacology; Zea mays
TL;DR: Results from this study indicate that wet distillers grains with solubles (WDGS) may have an effect on the prevalence of E. coli O157 and the concentration of selected antimicrobial resistance genes, but does not appear to affect antimicrobial susceptibility patterns in Enterococcus and genericE. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2008 journal article

Feeding Supplemental Dried Distiller’s Grains Increases Faecal Shedding of Escherichia coli O157 in Experimentally Inoculated Calves

Zoonoses and Public Health, 55(3), 125–132.

By: M. Jacob*, G. Parsons*, M. Shelor*, J. Fox*, J. Drouillard*, D. Thomson*, D. Renter*, T. Nagaraja*

MeSH headings : Animal Feed; Animals; Cattle / metabolism; Cattle / microbiology; Cecum / microbiology; Colon / microbiology; Colony Count, Microbial / veterinary; Consumer Product Safety; Disease Reservoirs / microbiology; Disease Reservoirs / veterinary; Edible Grain / metabolism; Escherichia coli Infections / transmission; Escherichia coli Infections / veterinary; Escherichia coli O157 / growth & development; Escherichia coli O157 / isolation & purification; Escherichia coli O157 / metabolism; Feces / microbiology; Food Contamination; Humans; Male; Meat / microbiology; Random Allocation; Rectum / microbiology; Rumen / metabolism
TL;DR: The results indicate that E. coli O157 gut persistence and faecal prevalence increased in calves fed DDG, which potentially have important implications for food safety. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2008 journal article

Niche Marketing Production Practices for Beef Cattle in the United States and Prevalence of Foodborne Pathogens

Foodborne Pathogens and Disease, 5(5), 559–569.

By: J. Fox*, S. Reinstein*, M. Jacob* & T. Nagaraja*

MeSH headings : Animals; Cattle; Consumer Product Safety / standards; Food Industry / economics; Food Microbiology; Marketing / economics; Meat / economics; Meat / standards; Prevalence; United States
TL;DR: This review outlines typical production practices for niche-market beef production systems in the United States and compares prevalence estimates of foodborne pathogens in animals and produce from conventional and niche- market production systems. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2007 journal article

Effects of Dried Distillers' Grain on Fecal Prevalence and Growth of Escherichia coli O157 in Batch Culture Fermentations from Cattle

Applied and Environmental Microbiology, 74(1), 38–43.

By: M. Jacob*, J. Fox, J. Drouillard*, D. Renter & T. Nagaraja

MeSH headings : Animals; Cattle; Cattle Diseases / microbiology; Colony Count, Microbial; Edible Grain / metabolism; Escherichia coli Infections / microbiology; Escherichia coli O157 / growth & development; Escherichia coli O157 / isolation & purification; Escherichia coli O157 / metabolism; Feces / microbiology; Fermentation; Rumen / microbiology; Zea mays / metabolism
TL;DR: The results indicate that there is a positive association between DDG and E. coli O157 in cattle, and the findings should have important ramifications for food safety. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

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