Megan Jacob

Gilbertie, J. M., Levent, G., Norman, K. N., Vinasco, J., Scott, H. M., & Jacob, M. E. (2020). Comprehensive phenotypic and genotypic characterization and comparison of virulence, biofilm, and antimicrobial resistance in urinary Escherichia coli isolated from canines. VETERINARY MICROBIOLOGY, 249. https://doi.org/10.1016/j.vetmic.2020.108822

Eichhorn, I., Luebke-Becker, A., Lapschies, A.-M., Jacob, M., Baeumer, W., & Fulde, M. (2020). Draft Genome Sequence of Staphylococcus pseudintermedius Strain 13-13613, Isolated from a Case of Canine Pyoderma. MICROBIOLOGY RESOURCE ANNOUNCEMENTS, 9(7). https://doi.org/10.1128/MRA.00027-20

Jacob, M. E., Keelara, S., Aidara-Kane, A., Alvarez, J. R. M., & Fedorka-Cray, P. J. (2020). Optimizing a Screening Protocol for Potential Extended-Spectrum beta-Lactamase Escherichia coli on MacConkey Agar for Use in a Global Surveillance Program. JOURNAL OF CLINICAL MICROBIOLOGY, 58(9). https://doi.org/10.1128/JCM.01039-19

Gilbertie, J. M., Schaer, T. P., Schubert, A. G., Jacob, M. E., Menegatti, S., Lavoie, R. A., & Schnabel, L. V. (2020). Platelet-rich plasma lysate displays antibiofilm properties and restores antimicrobial activity against synovial fluid biofilms in vitro. JOURNAL OF ORTHOPAEDIC RESEARCH. https://doi.org/10.1002/jor.24584

Carlson, A. R., Nixon, E., Jacob, M. E., & Messenger, K. M. (2020). Sterility and concentration of liposomal bupivacaine single-use vial when used in a multiple-dose manner. VETERINARY SURGERY. https://doi.org/10.1111/vsu.13380

Foster, D. M., Jacob, M. E., Farmer, K. A., Callahan, B. J., Theriot, C. M., Kathariou, S., … Papich, M. G. (2019). Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers. PLOS ONE, 14(10). https://doi.org/10.1371/journal.pone.0223378

Scharf, V. F., Dent, B., Jacob, M. E., & Moore, B. (2019). Efficacy of vaporized hydrogen peroxide for repeated sterilization of a single-use single-incision laparoscopic surgery port. VETERINARY SURGERY, 48, O59–O65. https://doi.org/10.1111/vsu.12905

Ceric, O., Tyson, G. H., Goodman, L. B., Mitchell, P. K., Zhang, Y., Prarat, M., … Reimschuessel, R. (2019). Enhancing the one health initiative by using whole genome sequencing to monitor antimicrobial resistance of animal pathogens: Vet-LIRN collaborative project with veterinary diagnostic laboratories in United States and Canada. BMC VETERINARY RESEARCH, 15. https://doi.org/10.1186/s12917-019-1864-2

Gilbertie, J. M., Schnabel, L. V., Hickok, N. J., Jacob, M. E., Conlon, B. P., Shapiro, I. M., … Schaer, T. P. (2019). Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections. PLOS ONE, 14(8). https://doi.org/10.1371/journal.pone.0221012

Cullen, M., Jacob, M. E., Cornish, V., VanderSchel, I. Q., Cotter, H. V. T., Cubeta, M. A., … Gilger, B. C. (2019). Multi-locus DNA sequence analysis, antifungal agent susceptibility, and fungal keratitis outcome in horses from Southeastern United States. PLOS ONE, 14(3). https://doi.org/10.1371/journal.pone.0214214

Barash, N. R., Birkenheuer, A. J., Vaden, S. L., & Jacob, M. E. (2018). Agreement between Parallel Canine Blood and Urine Cultures: Is Urine Culture the Poor Man's Blood Culture? JOURNAL OF CLINICAL MICROBIOLOGY, 56(9). https://doi.org/10.1128/JCM.00506-18

Kern, Z. T., Jacob, M. E., Gilbertie, J. M., Vaden, S. L., & Lyle, S. K. (2018). Characteristics of Dogs with Biofilm-Forming Escherichia Coli Urinary Tract Infections. JOURNAL OF VETERINARY INTERNAL MEDICINE, 32(5), 1645–1651. https://doi.org/10.1111/jvim.15231

Banovic, F., Olivry, T., Baumer, W., Paps, J., Stahl, J., Rogers, A., & Jacob, M. (2018). Diluted sodium hypochlorite (bleach) in dogs: antiseptic efficacy, local tolerability and in vitro effect on skin barrier function and inflammation. Veterinary Dermatology, 29(1). https://doi.org/10.1111/vde.12487

Ferguson, K. M., Jacob, M. E., Theriot, C. M., Callahan, B. J., Prange, T., Papich, M. G., & Foster, D. M. (2018). Dosing Regimen of Enrofloxacin Impacts Intestinal Pharmacokinetics and the Fecal Microbiota in Steers. FRONTIERS IN MICROBIOLOGY, 9. https://doi.org/10.3389/fmicb.2018.02190

Sylvester, H. J., Griffith, E. H., Jacob, M. E., & Foster, D. M. (2018). Factors associated with strongyle infection in goats at the individual and farm level. JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 253(7), 907–917. https://doi.org/10.2460/javma.253.7.907

Gilbertie, J. M., Schnabel, L. V., Stefanovski, D., Kelly, D. J., Jacob, M. E., & Schaer, T. P. (2018). Gram-negative multi-drug resistant bacteria influence survival to discharge for horses with septic synovial structures: 206 Cases (2010-2015). VETERINARY MICROBIOLOGY, 226, 64–73. https://doi.org/10.1016/j.vetmic.2018.10.009

Whitehead, M. C., Vanetten, C. L., Jacob, M. E., & Harrison, T. M. (2018). Microbial integrity of preservative-free alfaxalone in a multiple-use system for two storage conditions and three handling techniques. American Journal of Veterinary Research, 79(7), 704–710. https://doi.org/10.2460/ajvr.79.7.704

Watson, V. E., Jacob, M. E., Flowers, J. R., Strong, S. J., DebRoy, C., & Gookin, J. L. (2017). Association of Atypical Enteropathogenic Escherichia coli with Diarrhea and Related Mortality in Kittens. Journal of Clinical Microbiology, 55(9), 2719–2735. https://doi.org/10.1128/jcm.00403-17

Mohiti-Asli, M., Risselada, M., Jacob, M., Pourdeyhimi, B., & Loboa, E. G. (2017). Creation and evaluation of new porcine model for investigation of treatments of surgical site infection. Tissue Engineering. Part C, Methods, 23(11), 795–803. https://doi.org/10.1089/ten.tec.2017.0024

Swift, J. M., Foster, D. M., Rogers, A. T., Sylvester, H. J., Griffith, E. H., & Jacob, M. E. (2017). Efficacy of an Escherichia coli O157:H7 SRP vaccine in orally challenged goats and strain persistence over time. Foodborne Pathogens and Disease, 14(3), 160–166. https://doi.org/10.1089/fpd.2016.2213

Bäumer, W., Bizikova, P., Jacob, M., & Linder, K. E. (2017). Establishing a canine superficial pyoderma model. Journal of Applied Microbiology, 122(2), 331–337. https://doi.org/10.1111/jam.13362

Fogle, J., Jacob, M., Blikslager, A., Edwards, A., Wagner, B., Dean, K., & Fogle, C. (2016). Comparison of lipopolysaccharides and soluble CD14 measurement between clinically endotoxaemic and nonendotoxaemic horses. Equine Veterinary Journal, 49(2), 155–159. https://doi.org/10.1111/evj.12582

Jacob, M. E., Crowell, M. D., Fauls, M. B., Griffith, E. H., & Ferris, K. K. (2016). Diagnostic accuracy of a rapid immunoassay for point-of-care detection of urinary tract infection in dogs. American Journal of Veterinary Research, 77(2), 162–166. https://doi.org/10.2460/ajvr.77.2.162

Foster, D. M., Poulsen, K. P., Sylvester, H. J., Jacob, M. E., Casulli, K. E., & Farkas, B. E. (2016). Effect of high-pressure processing of bovine colostrum on immunoglobulin G concentration, pathogens, viscosity, and transfer of passive immunity to calves. Journal of Dairy Science, 99(11), 8575–8588. https://doi.org/10.3168/jds.2016-11204

Wilson, B. K., Holland, B. P., Step, D. L., Jacob, M. E., VanOverbeke, D. L., Richards, C. J., … Krehbiel, C. R. (2016). Feeding wet distillers grains plus solubles with and without a direct-fed microbial to determine performance, carcass characteristics, and fecal shedding of Escherichia coli O157:H7 in feedlot heifers. Journal of Animal Science, 94(1), 297–305. https://doi.org/10.2527/jas.2015-9601

Palerme, J.-S., Pan, P. C., Parsons, C. T., Kathariou, S., Ward, T. J., & Jacob, M. E. (2016). Isolation and characterization of atypical Listeria monocytogenes associated with a canine urinary tract infection. Journal of Veterinary Diagnostic Investigation, 28(5), 604–607. https://doi.org/10.1177/1040638716661381

Pritchard, J. C., Jacob, M. E., Ward, T. J., Parsons, C. T., Kathariou, S., & Wood, M. W. (2016). Listeria monocytogenes septicemia in an immunocompromised dog. Veterinary Clinical Pathology, 45(2), 254–259. https://doi.org/10.1111/vcp.12363

Tham, H. L., Jacob, M. E., & Bizikova, P. (2016). Molecular confirmation of shampoo as the putative source of Pseudomonas aeruginosa-induced postgrooming furunculosis in a dog. Veterinary Dermatology, 27(4), 320–380. https://doi.org/10.1111/vde.12332

Banovic, F., Koch, S., Robson, D., Jacob, M., & Olivry, T. (2015). Deep pyoderma caused by Burkholderia cepacia complex associated with ciclosporin administration in dogs: A case series. Veterinary Dermatology, 26(4), 287-. https://doi.org/10.1111/vde.12210

Jacob, M. E., Hoppin, J. A., Steers, N., Davis, J. L., Davidson, G., Hansen, B., … Papich, M. G. (2015). Opinions of clinical veterinarians at a US veterinary teaching hospital regarding antimicrobial use and antimicrobial-resistant infections. Journal of the American Veterinary Medical Association, 247(8), 938–944. https://doi.org/10.2460/javma.247.8.938

Foster, D. M., Jacob, M. E., Warren, C. D., & Papich, M. G. (2015). Pharmacokinetics of enrofloxacin and ceftiofur in plasma, interstitial fluid, and gastrointestinal tract of calves after subcutaneous injection, and bactericidal impacts on representative enteric bacteria. Journal of Veterinary Pharmacology and Therapeutics, 39(1), 62–71. https://doi.org/10.1111/jvp.12236

Jacob, M. E., Foster, D. M., Rogers, A. T., Balcomb, C. C., & Sanderson, M. W. (2015). Prevalence and relatedness of Escherichia coli O157:H7 strains in the feces and on the hides and carcasses of U.S. meat goats at slaughter (vol 79, pg 4154, 2013). Applied and Environmental Microbiology, Vol. 81, pp. 462–462.

Jacob, M. E., Bai, J., Renter, D. G., Rogers, A. T., Shi, X., & Nagaraja, T. G. (2014). Comparing real-time and conventional PCR to culture-based methods for detecting and quantifying Escherichia coli O157 in cattle feces. Journal of Food Protection, 77(2), 314–319. https://doi.org/10.4315/0362-028x.jfp-13-304

Edwardsiella tarda and Aeromonas hydrophila isolated from diseased Southern flounder (Paralichthys lethostigma) are virulent to channel catfish and Nile tilapia. (2014). Journal of Coastal Life Medicine. https://doi.org/10.12980/jclm.2.2014jclm-2014-0005

Warren, C. D., Prange, T., Campbell, N. B., Gerard, M. P., Martin, L. G., Jacob, M. E., … Foster, D. M. (2014). Implantation of an ultrafiltration device in the ileum and spiral colon of steers to continuously collect intestinal fluid. Research in Veterinary Science, 97(3), 611–615. https://doi.org/10.1016/j.rvsc.2014.10.012

Hutchins, R. G., Vaden, S. L., Jacob, M. E., Harris, T. L., Bowles, K. D., Wood, M. W., & Bailey, C. S. (2014). Vaginal microbiota of spayed dogs with or without recurrent urinary tract infections. Journal of Veterinary Internal Medicine, 28(2), 300–304. https://doi.org/10.1111/jvim.12299

Jacob, M. E., Foster, D. M., Rogers, A. T., Balcomb, C. C., Shi, X., & Nagaraja, T. G. (2013). Evidence of non-O157 Shiga toxin-producing Escherichia coli in the feces of meat goats at a US slaughter plant. Journal of Food Protection, 76(9), 1626–1629. https://doi.org/10.4315/0362-028x.jfp-13-064

Jacob, M. E., Foster, D. M., Rogers, A. T., Balcomb, C. C., & Sanderson, M. W. (2013). Prevalence and relatedness of Escherichia coli O157:H7 strains in the feces and on the hides and carcasses of US meat goats at slaughter. Applied and Environmental Microbiology, 79(13), 4154–4158. https://doi.org/10.1128/aem.00772-13

Hutchins, R. G., Bailey, C. S., Jacob, M. E., Harris, T. L., Wood, M. W., Saker, K. E., & Vaden, S. L. (2013). The effect of an oral probiotic containing lactobacillus, bifidobacterium, and bacillus species on the vaginal microbiota of spayed female dogs. Journal of Veterinary Internal Medicine, 27(6), 1368–1371. https://doi.org/10.1111/jvim.12174

Jacob, M. E., Shi, X. R., An, B. Y., Nagaraja, T. G., & Bai, J. F. (2012). Evaluation of a multiplex real-time polymerase chain reaction for the quantification of Escherichia coli O157 in cattle feces. Foodborne Pathogens and Disease, 9(1), 79–85. https://doi.org/10.1089/fpd.2011.0947

Jacob, M. E., Almes, K. M., Shi, X., Sargeant, J. M., & Nagaraja, T. G. (2011). Escherichia coli O157:H7 genetic diversity in bovine fecal samples. Journal of Food Protection, 74(7), 1186–1188. https://doi.org/10.4315/0362-028x.jfp-11-022

Dodd, C. C., Sanderson, M. W., Jacob, M. E., & Renter, D. G. (2011). Modeling Preharvest and Harvest Interventions for Escherichia coli O157 Contamination of Beef Cattle Carcasses. Journal of Food Protection, 74(9), 1422–1433. https://doi.org/10.4315/0362-028x.jfp-10-516

Jacob, M. E., Renter, D. G., & Nagaraja, T. G. (2010). Animal- and Truckload-Level Associations between Escherichia coli O157:H7 in Feces and on Hides at Harvest and Contamination of Preevisceration Beef Carcasses. Journal of Food Protection, 73(6), 1030–1037. https://doi.org/10.4315/0362-028x-73.6.1030

Jacob, M. E., Fox, J. T., Nagaraja, T. G., Drouillard, J. S., Amachawadi, R. G., & Narayanan, S. K. (2010). Effects of Feeding Elevated Concentrations of Copper and Zinc on the Antimicrobial Susceptibilities of Fecal Bacteria in Feedlot Cattle. Foodborne Pathogens and Disease, 7(6), 643–648. https://doi.org/10.1089/fpd.2009.0401

Jacob, M. E., Paddock, Z. D., Renter, D. G., Lechtenberg, K. F., & Nagaraja, T. G. (2010). Inclusion of Dried or Wet Distillers' Grains at Different Levels in Diets of Feedlot Cattle Affects Fecal Shedding of Escherichia coli O157:H7. Applied and Environmental Microbiology, 76(21), 7238–7242. https://doi.org/10.1128/aem.01221-10

Amachawadi, R. G., Shelton, N. W., Jacob, M. E., Shi, X., Narayanan, S. K., Zurek, L., … Nagaraja, T. G. (2010). Occurrence of tcrB, a Transferable Copper Resistance Gene, in Fecal Enterococci of Swine. Foodborne Pathogens and Disease, 7(9), 1089–1097. https://doi.org/10.1089/fpd.2010.0540

Jacob, M. E., Callaway, T. R., & Nagaraja, T. G. (2009). Dietary Interactions and Interventions Affecting Escherichia coli O157 Colonization and Shedding in Cattle. Foodborne Pathogens and Disease, 6(7), 785–792. https://doi.org/10.1089/fpd.2009.0306

Jacob, M. E., Fox, J. T., Drouillard, J. S., Renter, D. G., & Nagaraja, T. G. (2009). Evaluation of Feeding Dried Distiller's Grains with Solubles and Dry-Rolled Corn on the Fecal Prevalence of Escherichia coli O157:H7 and Salmonella spp. in Cattle. Foodborne Pathogens and Disease, 6(2), 145–153. https://doi.org/10.1089/fpd.2008.0159

Jacob, M. E., Fox, J. T., Reinstein, S. L., & Nagaraja, T. G. (2008). Antimicrobial Susceptibility of Foodborne Pathogens in Organic or Natural Production Systems: An Overview. Foodborne Pathogens and Disease, 5(6), 721–730. https://doi.org/10.1089/fpd.2008.0095

Jacob, M. E., Fox, J. T., Narayanan, S. K., Drouillard, J. S., Renter, D. G., & Nagaraja, T. G. (2008). Effects of feeding wet corn distillers grains with solubles with or without monensin and tylosin on the prevalence and antimicrobial susceptibilities of fecal foodborne pathogenic and commensal bacteria in feedlot cattle1. Journal of Animal Science, 86(5), 1182–1190. https://doi.org/10.2527/jas.2007-0091

Jacob, M. E., Parsons, G. L., Shelor, M. K., Fox, J. T., Drouillard, J. S., Thomson, D. U., … Nagaraja, T. G. (2008). Feeding Supplemental Dried Distiller’s Grains Increases Faecal Shedding of Escherichia coli O157 in Experimentally Inoculated Calves. Zoonoses and Public Health, 55(3), 125–132. https://doi.org/10.1111/j.1863-2378.2008.01115.x

Fox, J. T., Reinstein, S., Jacob, M. E., & Nagaraja, T. G. (2008). Niche Marketing Production Practices for Beef Cattle in the United States and Prevalence of Foodborne Pathogens. Foodborne Pathogens and Disease, 5(5), 559–569. https://doi.org/10.1089/fpd.2008.0094

Jacob, M. E., Fox, J. T., Drouillard, J. S., Renter, D. G., & Nagaraja, T. G. (2007). Effects of Dried Distillers' Grain on Fecal Prevalence and Growth of Escherichia coli O157 in Batch Culture Fermentations from Cattle. Applied and Environmental Microbiology, 74(1), 38–43. https://doi.org/10.1128/aem.01842-07