@article{wood_morgan_ange-van heugten_serrano_minter_fellner_stoskopf_2022, title={Observable Metabolites and Metabolomic Sampling Protocols for Managed African Savanna Elephant (Loxodonta africana) Whole Blood Using H-NMR Spectroscopy}, volume={12}, ISSN={["2218-1989"]}, url={https://doi.org/10.3390/metabo12050400}, DOI={10.3390/metabo12050400}, abstractNote={We used nuclear magnetic spectroscopy (NMR) to evaluate the metabolomics of heparinized whole blood drawn from six African savanna elephants (Loxodonta africana) maintained on a well characterized diet. Whole blood samples obtained under behavioral restraint, then quickly frozen in liquid nitrogen, were stored at −80 °C until analysis. Frozen samples were thawed under controlled conditions and extracted with methanol and chloroform to separate the polar and non-polar metabolites. We identified 18 polar metabolites and 14 non-polar lipids using one-dimensional (1D) and two-dimensional (2D) NMR spectra. Despite unexpected rouleaux formation in the thawed frozen samples, spectra were consistent among animals and did not vary dramatically with age or the sex of the animal.}, number={5}, journal={Metabolites}, author={Wood, J. and Morgan, D.R. and Ange-van Heugten, K. and Serrano, M. and Minter, L.J. and Fellner, V. and Stoskopf, M.K.}, year={2022}, pages={400} }
 @article{harms_ruterbories_stacy_christiansen_papich_lynch_barratclough_serrano_2021, title={SAFETY OF MULTIPLE-DOSE INTRAMUSCULAR KETOPROFEN TREATMENT IN LOGGERHEAD TURTLES (CARETTA CARETTA)}, volume={52}, ISSN={["1937-2825"]}, DOI={10.1638/2020-0159}, abstractNote={Abstract: Sea turtles are frequently presented for rehabilitation with injuries for which analgesic treatment is warranted. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely used in clinical veterinary medicine for musculoskeletal pain relief. Pharmacokinetics of 2 mg/kg IM have been studied in loggerhead sea turtles (Caretta caretta) as a single and a repeated dose q24hr for 3 days. Safety of longer term administration has not been performed, however, and NSAID use carries a risk of potential complications, including gastrointestinal ulceration, kidney damage, and bleeding. The objective of the current study was to determine the effects of a 5-day course of ketoprofen on thromboelastography (TEG) and hematological (including thrombocytes) and plasma biochemical analytes in loggerheads. A secondary objective was to determine 24-hr trough concentrations of ketoprofen after 5 days of treatment. Eight loggerheads were treated with ketoprofen 2 mg/kg IM q24hr for 5 days, and TEG, hematology, and plasma biochemistry panels were performed before and at the conclusion of treatment. Eight controls were treated with an equivalent volume of saline intramuscularly. Virtually no changes were detected before and after treatment or between treatment and control groups in any of the 24 endpoints evaluated, and marginal differences were not considered clinically relevant. Plasma ketoprofen concentrations after 5 days of treatment indicated no accumulation over that duration. Ketoprofen at 2 mg/kg IM q24hr for up to 5 days in loggerheads appears safe with respect to blood clotting and blood data, although other potential effects were not evaluated.}, number={1}, journal={JOURNAL OF ZOO AND WILDLIFE MEDICINE}, author={Harms, Craig A. and Ruterbories, Laura K. and Stacy, Nicole I and Christiansen, Emily F. and Papich, Mark G. and Lynch, Alex M. and Barratclough, Ashley and Serrano, Maria E.}, year={2021}, month={Mar}, pages={126–132} }
 @article{posner_applegate_cannedy_deresienski_mozzachio_serrano_lewbart_2020, title={Total injectable anesthesia of dogs and cats for remote location veterinary sterilization clinic}, volume={16}, ISSN={["1746-6148"]}, DOI={10.1186/s12917-020-02525-x}, abstractNote={Abstract}, number={1}, journal={BMC VETERINARY RESEARCH}, author={Posner, Lysa Pam and Applegate, Jeffrey and Cannedy, Allen and Deresienski, Diane and Mozzachio, Kristie and Serrano, Maria and Lewbart, Gregory}, year={2020}, month={Aug} }
 @article{minter_stoskopf_serrano_burrus_lewbart_2012, title={Suspected lead toxicosis in an electric eel, Electrophorus electricus (L.)}, volume={35}, ISSN={["0140-7775"]}, DOI={10.1111/j.1365-2761.2012.01386.x}, abstractNote={Journal of Fish DiseasesVolume 35, Issue 8 p. 603-606 Short Communication Suspected lead toxicosis in an electric eel, Electrophorus electricus (L.) L J Minter, L J Minter Environmental Medicine Consortium and Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USASearch for more papers by this authorM K Stoskopf, M K Stoskopf Environmental Medicine Consortium and Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USASearch for more papers by this authorM Serrano, M Serrano Environmental Medicine Consortium and Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USASearch for more papers by this authorO Burrus, O Burrus NC Aquarium/Roanoke Island, Manteo, NC, USASearch for more papers by this authorG A Lewbart, G A Lewbart Environmental Medicine Consortium and Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USASearch for more papers by this author L J Minter, L J Minter Environmental Medicine Consortium and Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USASearch for more papers by this authorM K Stoskopf, M K Stoskopf Environmental Medicine Consortium and Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USASearch for more papers by this authorM Serrano, M Serrano Environmental Medicine Consortium and Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USASearch for more papers by this authorO Burrus, O Burrus NC Aquarium/Roanoke Island, Manteo, NC, USASearch for more papers by this authorG A Lewbart, G A Lewbart Environmental Medicine Consortium and Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USASearch for more papers by this author First published: 21 May 2012 https://doi.org/10.1111/j.1365-2761.2012.01386.xCitations: 1 L J Minter, Environmental Medicine Consortium and Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, 1060 William Moore Dr, Raleigh, NC 27607, USA (e-mail: [email protected]) Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References Ayotunde E.O. & Ochang S.N. (2004) Ichthyhaematological studies on the electric catfish, Malapterurus electricus. Global Journal of Agricultural Science 3, 5–14. Google Scholar Barak N.E. & Mason C.F. (1990) Mercury, cadmium and lead in eels and roachs: the effect of size, season and locality on metal concentrations in flesh and liver. The Science of the Total Environment 92, 249–256. 10.1016/0048-9697(90)90334-Q CASPubMedWeb of Science®Google Scholar Blakley B.R. (1984) A retrospective study of lead poisoning in cattle. Veterinary and Human Toxicology 26, 505–507. CASPubMedWeb of Science®Google Scholar Bratton G.R. & Kowalczk D.F. (1989) Lead poisoning. In: Current Veterinary Therapy X (ed. by R.W. Kirk), pp 152–159. W.B. Saunders Co., Philadelphia, PA. Google Scholar Ciftci N., Cicik B., Erdem C. & Ay Ö. (2008) Effects of lead concentrations on sera parameters and hematocrit levels in Anguilla anguilla. Journal of Fisheries Science 2, 616–622. CASGoogle Scholar Dumonceaux G. & Harrison G.J. (1994) Toxins. In: Avian Medicine: Principles and Applications (ed. by B.W. Ritchie, G.J. Harrison & L.R. Harrison), pp 1030–1052. Wingers, Lake Worth, FL. Google Scholar Franson J.C. (1996) Interpretation of tissue lead residues in birds other than waterfowl. In: Environmental Contaminants in Wildlife: Interpreting Tissue Concentrations (ed. by W.N. Beyer, G.H. Heinz & A.W. Redmon-Norwood), pp 265–279. CRC Press, Boca Raton, FL. Google Scholar Martinez C.R., Nagae M.Y., Zaia C.V. & Zaia D.M. (2004) Acute morphological and physiological effects of lead in the neotropical fish Prochilodus lineatus. Brazilian Journal of Biology 64, 797–807. 10.1590/S1519-69842004000500009 CASPubMedGoogle Scholar Mautino M. (1997) Lead and zinc intoxication in zoological medicine: a review. Journal of Zoo and Wildlife Medicine 28, 28–35. CASPubMedWeb of Science®Google Scholar McDonald S.E. (1986) Lead poisoning in psittacine birds. In: Current Veterinary Therapy IX (ed. by R.W. Kirk), pp 713–718. W.B. Saunders Co. Philadelphia, PA. Web of Science®Google Scholar Morgan R.V., Moore F.M., Pearce L.K. & Rossi T. (1991) Clinical and laboratory findings in small companion animals with lead poisoning: 347 cases (1977–1986). Journal of the American Veterinary Medical Association 199, 93–97. CASPubMedWeb of Science®Google Scholar Penumarthy L., Oehme F.W. & Hayes R.H. (1980) Lead, cadmium, and mercury tissue residue in healthy swine, cattle, dogs, and horses from midwestern United States. Archives of Environmental Contamination and Toxicology 9, 193–206. 10.1007/BF01055374 CASPubMedWeb of Science®Google Scholar Poppenga R.H. (1992) Common toxicoses of waterfowl, loons, and raptors. In: Current Veterinary Therapy XI (ed. by R.W. Kirk), pp 183–188. W.B. Saunders Co., Philadelphia, PA. Google Scholar Prasad G. & Charles S. (2010) Haematology and leucocyte enzyme cytochemistry of a threatened yellow catfish Horabagrus brachysoma. Fish Physiology and Biochemistry 36, 435–443. 10.1007/s10695-009-9313-y CASPubMedWeb of Science®Google Scholar Santos M.A. & Aristides H. (1990) Influence of inorganic lead on the biochemical blood composition of the eel, Anguilla anguilla. Ecotoxicology and Environmental Safety 20, 7–9. 10.1016/0147-6513(90)90040-C CASPubMedWeb of Science®Google Scholar Shah S.L. (2006) Hematological parameters in tench Tinca tinca after short term exposure to lead. Journal of Applied Toxicology 26, 223–228. 10.1002/jat.1129 CASPubMedWeb of Science®Google Scholar Silbergeld E.K. & Goldberg A.M. (1980) Problems in experimental studies of lead poisoning. In: Lead Toxicity (ed. by R.L. Singhal & J.A. Thomas), pp 19–41. Urban & Schwarzenberg, Baltimore. Google Scholar Sorensen E.M. (1991) Lead. In: Metal Poisoning in Fish (ed. by E.M. Sorensen), pp 95–110. CRC Press, Boca Raton. Web of Science®Google Scholar Zook B.C., Sauer R.M. & Garner F.M. (1972) Lead poisoning in captive wild animals. Journal of Wildlife Disease 8, 264–272. 10.7589/0090-3558-8.3.264 CASPubMedGoogle Scholar Citing Literature Volume35, Issue8August 2012Pages 603-606 ReferencesRelatedInformation}, number={8}, journal={JOURNAL OF FISH DISEASES}, author={Minter, L. J. and Stoskopf, M. K. and Serrano, M. and Burrus, O. and Lewbart, G. A.}, year={2012}, month={Aug}, pages={603–606} }