Michael Gamcsik

Works (20)

Updated: April 11th, 2023 10:13

2022 journal article

Direct Detection of Glutathione Biosynthesis, Conjugation, Depletion and Recovery in Intact Hepatoma Cells


By: R. Jeffries n, S. Gomez, J. Macdonald & M. Gamcsik

author keywords: glutathione; antioxidant; nuclear magnetic resonance spectroscopy; noninvasive; alkylating agent; metabolism
Source: Web Of Science
Added: June 6, 2022

2022 article

Highlighting Functional Mass Spectrometry Imaging Methods in Bioanalysis

Mellinger, A. L., Muddiman, D. C., & Gamcsik, M. P. (2022, June 27). JOURNAL OF PROTEOME RESEARCH, Vol. 6.

By: A. Mellinger, D. Muddiman & M. Gamcsik

author keywords: mass spectrometry imaging; kinetics; rate; isotope; metabolism; dynamics
Sources: Web Of Science, ORCID
Added: July 11, 2022

2022 journal article

Mapping glycine uptake and its metabolic conversion to glutathione in mouse mammary tumors using functional mass spectrometry imaging


Sources: Web Of Science, ORCID
Added: January 23, 2023

2022 journal article

Multiple Infusion Start Time Mass Spectrometry Imaging of Dynamic SIL-Glutathione Biosynthesis Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization


By: A. Mellinger, K. Garrard n, S. Khodjaniyazova, Z. Rabbani, M. Gamcsik & D. Muddiman

author keywords: IR-MALDESI; mass spectrometry imaging; stable isotope labeling; glutathione; kinetic metabolism
Sources: Web Of Science, ORCID
Added: May 2, 2022

2021 journal article

A multiwell plate-based system for toxicity screening under multiple static or cycling oxygen environments


By: M. Yao n, G. Walker & M. Gamcsik

Source: Web Of Science
Added: March 22, 2021

2019 journal article

Flow-Encoded Oxygen Control to Track the Time-Dependence of Molecular Changes Induced by Static or Cycling Hypoxia

ANALYTICAL CHEMISTRY, 91(23), 15032–15039.

By: M. Yao, Z. Rabbani, T. Sattler, K. Nguyen*, D. Zaharoff, G. Walker, M. Gamcsik

Source: Web Of Science
Added: December 30, 2019

2018 journal article

Mixing and delivery of multiple controlled oxygen environments to a single multiwell culture plate


By: M. Yao, T. Sattler, Z. Rabbani, T. Pulliam n, G. Walker & M. Gamcsik

author keywords: cell culture; cycling hypoxia; finite element analysis; oxygen diffusion; permeability
Source: Web Of Science
Added: December 10, 2018

2015 journal article

Biocompatibility of Tygon® tubing in microfluidic cell culture

Biomedical Microdevices, 17(1).

By: X. Jiang*, R. Jeffries*, M. Acosta*, A. Tikunov*, J. Macdonald*, G. Walker, M. Gamcsik

author keywords: Biomaterial; Cancer cell; Biocompatibility; Toxicity; Polyvinylchloride; Spectroscopy
Source: Crossref
Added: August 28, 2020

2014 journal article

A microfluidic device to study cancer metastasis under chronic and intermittent hypoxia

Biomicrofluidics, 8(5), 054117.

By: M. Acosta n, X. Jiang, P. Huang*, K. Cutler*, C. Grant, G. Walker, M. Gamcsik

Sources: Crossref, Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Noninvasive In Vivo Magnetic Resonance Measures of Glutathione Synthesis in Human and Rat Liver as an Oxidative Stress Biomarker

HEPATOLOGY, 59(6), 2321–2330.

By: J. Skamarauskas*, F. Oakley*, F. Smith*, C. Bawn*, M. Dunn*, D. Vidler*, M. Clemence*, P. Blain* ...

Source: Web Of Science
Added: August 6, 2018

2012 journal article

13C magnetic resonance spectroscopy detection of changes in serine isotopomers reflects changes in mitochondrial redox status


By: C. Johnson*, A. Tikunov*, H. Lee*, J. Wolak*, P. Pediaditakis*, D. Romney*, E. Holmuhamedov*, M. Gamcsik, J. Macdonald*

author keywords: serine 13C isotopomers; 13C NMR spectroscopy; mitochondrial redox; 2-13C-glycine; hepatocytes; confocal microscopy
Source: Web Of Science
Added: August 6, 2018

2012 journal article

In vivo MR studies of glycine and glutathione metabolism in a rat mammary tumor

NMR IN BIOMEDICINE, 25(2), 271–278.

By: P. Thelwall*, N. Simpson*, Z. Rabbani*, M. Clark*, R. Pourdeyhimi n, J. Macdonald, S. Blackband*, M. Gamcsik

author keywords: glutathione; MR; serine; metabolism; trans-sulfuration
Source: Web Of Science
Added: August 6, 2018

2011 journal article

In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis

PLoS Pathogens, 7(7).

By: N. Grahl, S. Puttikamonkul, J. Macdonald, M. Gamcsik, L. Ngo, T. Hohl, R. Cramer

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Synthesis of 13C-labeled derivatives of cysteine for magnetic resonance imaging studies of drug uptake and conversion to glutathione in rat brain

Journal of Labelled Compounds and Radiopharmaceuticals, 54(9), 607–612.

By: P. Amoyaw*, J. Springer*, M. Gamcsik, R. Mutesi*, M. D'Alessandro*, C. Dempsey*, S. Ludeman*

author keywords: C-13-labeling; synthesis; N-acetylcysteine; 2-oxothiazolidine-4-carboxylic acid; OTZ; ethyl glutamylcysteinate
Sources: Crossref, NC State University Libraries
Added: August 6, 2018

2010 journal article

Non-invasive Monitoring of L-2-Oxothiazolidine-4-Carboxylate Metabolism in the Rat Brain by In vivo 13C Magnetic Resonance Spectroscopy

Neurochemical Research, 36(3), 443–451.

By: M. Gamcsik, M. Daniel Clark*, S. Ludeman*, J. Springer*, M. D’Alessandro*, N. Simpson*, R. Pourdeyhimi*, C. Bryce Johnson ...

author keywords: Magnetic resonance; Metabolism; Cysteine; Glutathione; Taurine
Sources: Crossref, ORCID
Added: August 27, 2020

2005 journal article

Intrastrand base-stacking buttresses widening of major groove in interstrand cross-linked B-DNA

Bioorganic & Medicinal Chemistry, 13(14), 4580–4587.

By: M. da Silva*, R. Bierbryer*, C. Wilds*, A. Noronha*, O. Colvin*, P. Miller*, M. Gamcsik

author keywords: DNA interstrand crosslinks; DNA repair; solution NMR structure
Source: Crossref
Added: August 28, 2020

2005 journal article

Structure, Flexibility, and Repair of Two Different Orientations of the Same Alkyl Interstrand DNA Cross-Link†

Biochemistry, 44(18), 6764–6775.

By: D. Noll*, M. Webba da Silva*, A. Noronha*, C. Wilds*, O. Colvin*, M. Gamcsik, P. Miller*

Source: Crossref
Added: August 28, 2020

2004 journal article

Accommodation of Mispair Aligned N3T-Ethyl-N3T DNA Interstrand Cross Link†

Biochemistry, 43(39), 12549–12554.

By: M. Webba da Silva*, C. Wilds*, A. Noronha*, O. Colvin*, P. Miller* & M. Gamcsik

Source: Crossref
Added: January 21, 2021

2004 journal article

Role of glutathione and nucleotide excision repair in modulation of cisplatin activity with O6-benzylguanine

Cancer Chemotherapy and Pharmacology, 55(4), 333–342.

By: M. Fishel*, M. Gamcsik, S. Delaney*, E. Zuhowski*, V. Maher*, T. Karrison*, R. Moschel*, M. Egorin*, M. Dolan*

author keywords: cisplatin; modulation; chemotherapy
Source: Crossref
Added: January 21, 2021

1996 journal article

A versatile oxygenator and perfusion system for magnetic resonance studies

Biotechnology and Bioengineering, 49(3), 348–354.

By: M. Gamcsik, J. Forder, K. Millis & K. McGovern

author keywords: oxygenator; NMR spectroscopy; organ perfusion; mammalian cell culture
Source: Crossref
Added: January 28, 2021