Michael Gamcsik

Works (20)

Updated: April 11th, 2023 10:13

2022 journal article

Direct Detection of Glutathione Biosynthesis, Conjugation, Depletion and Recovery in Intact Hepatoma Cells

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(9).

By: R. Jeffries n, S. Gomez, J. Macdonald & M. Gamcsik

author keywords: glutathione; antioxidant; nuclear magnetic resonance spectroscopy; noninvasive; alkylating agent; metabolism
Source: Web Of Science
Added: June 6, 2022

2022 article

Highlighting Functional Mass Spectrometry Imaging Methods in Bioanalysis

Mellinger, A. L., Muddiman, D. C., & Gamcsik, M. P. (2022, June 27). JOURNAL OF PROTEOME RESEARCH, Vol. 6.

By: A. Mellinger, D. Muddiman & M. Gamcsik

author keywords: mass spectrometry imaging; kinetics; rate; isotope; metabolism; dynamics
Sources: Web Of Science, ORCID
Added: July 11, 2022

2022 journal article

Mapping glycine uptake and its metabolic conversion to glutathione in mouse mammary tumors using functional mass spectrometry imaging

FREE RADICAL BIOLOGY AND MEDICINE, 193, 677–684.

Sources: Web Of Science, ORCID
Added: January 23, 2023

2022 journal article

Multiple Infusion Start Time Mass Spectrometry Imaging of Dynamic SIL-Glutathione Biosynthesis Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

JOURNAL OF PROTEOME RESEARCH, 21(3), 747–757.

By: A. Mellinger, K. Garrard n, S. Khodjaniyazova, Z. Rabbani, M. Gamcsik & D. Muddiman

author keywords: IR-MALDESI; mass spectrometry imaging; stable isotope labeling; glutathione; kinetic metabolism
Sources: Web Of Science, ORCID
Added: May 2, 2022

2021 journal article

A multiwell plate-based system for toxicity screening under multiple static or cycling oxygen environments

SCIENTIFIC REPORTS, 11(1).

By: M. Yao n, G. Walker & M. Gamcsik

Source: Web Of Science
Added: March 22, 2021

2019 journal article

Flow-Encoded Oxygen Control to Track the Time-Dependence of Molecular Changes Induced by Static or Cycling Hypoxia

ANALYTICAL CHEMISTRY, 91(23), 15032–15039.

By: M. Yao, Z. Rabbani, T. Sattler, K. Nguyen*, D. Zaharoff, G. Walker, M. Gamcsik

Source: Web Of Science
Added: December 30, 2019

2018 journal article

Mixing and delivery of multiple controlled oxygen environments to a single multiwell culture plate

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 315(5), C766–C775.

By: M. Yao, T. Sattler, Z. Rabbani, T. Pulliam n, G. Walker & M. Gamcsik

author keywords: cell culture; cycling hypoxia; finite element analysis; oxygen diffusion; permeability
Source: Web Of Science
Added: December 10, 2018

2015 journal article

Biocompatibility of Tygon® tubing in microfluidic cell culture

Biomedical Microdevices, 17(1).

By: X. Jiang*, R. Jeffries*, M. Acosta*, A. Tikunov*, J. Macdonald*, G. Walker, M. Gamcsik

author keywords: Biomaterial; Cancer cell; Biocompatibility; Toxicity; Polyvinylchloride; Spectroscopy
Source: Crossref
Added: August 28, 2020

2014 journal article

A microfluidic device to study cancer metastasis under chronic and intermittent hypoxia

Biomicrofluidics, 8(5), 054117.

By: M. Acosta n, X. Jiang, P. Huang*, K. Cutler*, C. Grant, G. Walker, M. Gamcsik

Sources: Crossref, Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Noninvasive In Vivo Magnetic Resonance Measures of Glutathione Synthesis in Human and Rat Liver as an Oxidative Stress Biomarker

HEPATOLOGY, 59(6), 2321–2330.

By: J. Skamarauskas*, F. Oakley*, F. Smith*, C. Bawn*, M. Dunn*, D. Vidler*, M. Clemence*, P. Blain* ...

Source: Web Of Science
Added: August 6, 2018

2012 journal article

13C magnetic resonance spectroscopy detection of changes in serine isotopomers reflects changes in mitochondrial redox status

MAGNETIC RESONANCE IN MEDICINE, 68(3), 671–679.

By: C. Johnson*, A. Tikunov*, H. Lee*, J. Wolak*, P. Pediaditakis*, D. Romney*, E. Holmuhamedov*, M. Gamcsik, J. Macdonald*

author keywords: serine 13C isotopomers; 13C NMR spectroscopy; mitochondrial redox; 2-13C-glycine; hepatocytes; confocal microscopy
Source: Web Of Science
Added: August 6, 2018

2012 journal article

In vivo MR studies of glycine and glutathione metabolism in a rat mammary tumor

NMR IN BIOMEDICINE, 25(2), 271–278.

By: P. Thelwall*, N. Simpson*, Z. Rabbani*, M. Clark*, R. Pourdeyhimi n, J. Macdonald, S. Blackband*, M. Gamcsik

author keywords: glutathione; MR; serine; metabolism; trans-sulfuration
Source: Web Of Science
Added: August 6, 2018

2011 journal article

In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis

PLoS Pathogens, 7(7).

By: N. Grahl, S. Puttikamonkul, J. Macdonald, M. Gamcsik, L. Ngo, T. Hohl, R. Cramer

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Synthesis of 13C-labeled derivatives of cysteine for magnetic resonance imaging studies of drug uptake and conversion to glutathione in rat brain

Journal of Labelled Compounds and Radiopharmaceuticals, 54(9), 607–612.

By: P. Amoyaw*, J. Springer*, M. Gamcsik, R. Mutesi*, M. D'Alessandro*, C. Dempsey*, S. Ludeman*

author keywords: C-13-labeling; synthesis; N-acetylcysteine; 2-oxothiazolidine-4-carboxylic acid; OTZ; ethyl glutamylcysteinate
Sources: Crossref, NC State University Libraries
Added: August 6, 2018

2010 journal article

Non-invasive Monitoring of L-2-Oxothiazolidine-4-Carboxylate Metabolism in the Rat Brain by In vivo 13C Magnetic Resonance Spectroscopy

Neurochemical Research, 36(3), 443–451.

By: M. Gamcsik, M. Daniel Clark*, S. Ludeman*, J. Springer*, M. D’Alessandro*, N. Simpson*, R. Pourdeyhimi*, C. Bryce Johnson ...

author keywords: Magnetic resonance; Metabolism; Cysteine; Glutathione; Taurine
Sources: Crossref, ORCID
Added: August 27, 2020

2005 journal article

Intrastrand base-stacking buttresses widening of major groove in interstrand cross-linked B-DNA

Bioorganic & Medicinal Chemistry, 13(14), 4580–4587.

By: M. da Silva*, R. Bierbryer*, C. Wilds*, A. Noronha*, O. Colvin*, P. Miller*, M. Gamcsik

author keywords: DNA interstrand crosslinks; DNA repair; solution NMR structure
Source: Crossref
Added: August 28, 2020

2005 journal article

Structure, Flexibility, and Repair of Two Different Orientations of the Same Alkyl Interstrand DNA Cross-Link†

Biochemistry, 44(18), 6764–6775.

By: D. Noll*, M. Webba da Silva*, A. Noronha*, C. Wilds*, O. Colvin*, M. Gamcsik, P. Miller*

Source: Crossref
Added: August 28, 2020

2004 journal article

Accommodation of Mispair Aligned N3T-Ethyl-N3T DNA Interstrand Cross Link†

Biochemistry, 43(39), 12549–12554.

By: M. Webba da Silva*, C. Wilds*, A. Noronha*, O. Colvin*, P. Miller* & M. Gamcsik

Source: Crossref
Added: January 21, 2021

2004 journal article

Role of glutathione and nucleotide excision repair in modulation of cisplatin activity with O6-benzylguanine

Cancer Chemotherapy and Pharmacology, 55(4), 333–342.

By: M. Fishel*, M. Gamcsik, S. Delaney*, E. Zuhowski*, V. Maher*, T. Karrison*, R. Moschel*, M. Egorin*, M. Dolan*

author keywords: cisplatin; modulation; chemotherapy
Source: Crossref
Added: January 21, 2021

1996 journal article

A versatile oxygenator and perfusion system for magnetic resonance studies

Biotechnology and Bioengineering, 49(3), 348–354.

By: M. Gamcsik, J. Forder, K. Millis & K. McGovern

author keywords: oxygenator; NMR spectroscopy; organ perfusion; mammalian cell culture
Source: Crossref
Added: January 28, 2021