M Gregory Forest
Works (8)
Updated: August 16th, 2023 21:16
2022 journal article
A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes
JOURNAL OF CONTROLLED RELEASE, 343, 518–527.
co-author countries:
United States of America 🇺🇸
author keywords: PBPK model; Polyethylene glycol; PEGylated liposomes; Accelerated blood clearance; Anti-PEG antibodies
MeSH headings : Animals; Antibodies; Kinetics; Liposomes; Mice; Polyethylene Glycols / pharmacokinetics; Positron Emission Tomography Computed Tomography; Tissue Distribution
Source: Web Of Science
Added: May 23, 2022
2021 journal article
Experimental Data and PBPK Modeling Quantify Antibody Interference in PEGylated Drug Carrier Delivery
BULLETIN OF MATHEMATICAL BIOLOGY, 83(12).
co-author countries:
United States of America 🇺🇸
author keywords: PBPK model; Latin hypercube sampling; Parameter optimization; Anti-PEG antibodies; PEGylated liposomes
MeSH headings : Animals; Drug Carriers; Mathematical Concepts; Mice; Models, Biological; Polyethylene Glycols / pharmacokinetics; Positron Emission Tomography Computed Tomography; Tissue Distribution
link.springer.com (publisher PDF)
Source: Web Of Science
Added: November 23, 2021
2020 journal article
LPS-binding IgG arrests actively motile Salmonella Typhimurium in gastrointestinal mucus
MUCOSAL IMMUNOLOGY, 13(5), 814–823.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Antibodies, Bacterial / immunology; Disease Models, Animal; Immunoglobulin Fab Fragments / immunology; Immunoglobulin Fc Fragments / immunology; Immunoglobulin G / immunology; Intestinal Mucosa; Lipopolysaccharides / immunology; Mice; Mucus / immunology; Mucus / microbiology; Polysaccharides / immunology; Protein Binding / immunology; Salmonella Infections / immunology; Salmonella Infections / microbiology; Salmonella typhimurium / immunology
Source: Web Of Science
Added: March 23, 2020
2020 journal article
Modeling the Mechanisms by Which Coexisting Biomolecular RNA-Protein Condensates Form
BULLETIN OF MATHEMATICAL BIOLOGY, 82(12).
co-author countries:
Canada 🇨🇦 United States of America 🇺🇸
author keywords: Liquid– liquid phase separation; Flory– Huggins; RNA– protein dynamics; Phase field model
MeSH headings : Biophysical Phenomena; Kinetics; Mathematical Concepts; Models, Biological; Proteins / metabolism; RNA / metabolism
Source: Web Of Science
Added: December 21, 2020
2020 journal article
Spatial heterogeneity of the cytosol revealed by machine learning-based 3D particle tracking
MOLECULAR BIOLOGY OF THE CELL, 31(14), 1498–1511.
co-author countries:
Canada 🇨🇦 United States of America 🇺🇸
MeSH headings : Cytoplasm / metabolism; Cytoplasm / physiology; Cytosol / metabolism; Cytosol / physiology; Eremothecium / metabolism; Image Processing, Computer-Assisted / methods; Machine Learning; Nanoparticles; Orientation, Spatial / physiology; Single Molecule Imaging / methods
Source: Web Of Science
Added: August 3, 2020
2019 journal article
Modeling Barrier Properties of Intestinal Mucus Reinforced with IgG and Secretory IgA against Motile Bacteria
ACS INFECTIOUS DISEASES, 5(9), 1570–1580.
co-author countries:
United States of America 🇺🇸
author keywords: mucin; immunoglobulins; mucosal immunity; pathogen
MeSH headings : Agglutination; Animals; Bacteria / immunology; Bacteria / pathogenicity; Binding Sites; Humans; Immunoglobulin A, Secretory / chemistry; Immunoglobulin A, Secretory / metabolism; Immunoglobulin G / chemistry; Immunoglobulin G / metabolism; Intestinal Mucosa / immunology; Models, Theoretical; Mucins / chemistry; Mucins / immunology; Protein Binding
Source: Web Of Science
Added: October 7, 2019
2019 journal article
Partial demixing of RNA-protein complexes leads to intradroplet patterning in phase-separated biological condensates
PHYSICAL REVIEW E, 99(1).
co-author countries:
Canada 🇨🇦 United States of America 🇺🇸
MeSH headings : Kinetics; Models, Biological; RNA / metabolism; RNA-Binding Proteins / metabolism
Source: Web Of Science
Added: April 20, 2020
2014 journal article
Transient Antibody-Mucin Interactions Produce a Dynamic Molecular Shield against Viral Invasion
BIOPHYSICAL JOURNAL, 106(9), 2028–2036.
co-author countries:
United States of America 🇺🇸
MeSH headings : Antibodies, Neutralizing / immunology; Antibodies, Neutralizing / metabolism; Antibodies, Viral / metabolism; Antibody Specificity; Cervix Uteri / virology; Female; HIV-1 / physiology; Humans; Immunoglobulin G / immunology; Kinetics; Mucins / metabolism; Mucus / virology; Protein Binding; Vagina / virology
Source: Web Of Science
Added: August 6, 2018
