Megan Chambers

Works (1)

Updated: July 5th, 2023 14:38

2020 journal article

Structural and hemodynamic properties of murine pulmonary arterial networks under hypoxia-induced pulmonary hypertension

PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, 234(11), 1312–1329.

By: M. Chambers n, M. Colebank n , M. Qureshi n, R. Clipp * & M. Olufsen n

author keywords: Pulmonary hypertension; fractal networks; image segmentation; center line extraction; one-dimensional fluid dynamics; Navier-Stokes equations
MeSH headings : Animals; Hemodynamics; Humans; Hypertension, Pulmonary / diagnostic imaging; Hypoxia; Mice; Models, Cardiovascular; Pulmonary Artery / diagnostic imaging; X-Ray Microtomography
TL;DR: This study demonstrates how to combine imaging data from microcomputed tomography images with hemodynamic pressure and flow waveforms from control and hypertensive mice to generate subject-specific arterial networks in which one-dimensional fluid dynamics modeling is used to predict blood Pressure and flow. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 31, 2020

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