Manasi Krishnakumar

Works (1)

Updated: June 23rd, 2023 22:05

2021 journal article

Fibrin‐specific poly(N‐isopropylacrylamide) nanogels for targeted delivery of tissue‐type plasminogen activator to treat thrombotic complications are well tolerated in vivo

Bioengineering & Translational Medicine, 7(2).

By: E. Mihalko n, K. Nellenbach n, M. Krishnakumar n, N. Moiseiwitsch n, J. Sollinger n, B. Cooley *, A. Brown n 

author keywords: disseminated intravascular coagulation; fibrin; nanogels; pNIPAM; targeted delivery; thrombosis; tissue plasminogen activator
topics (OpenAlex): Blood properties and coagulation; Blood Coagulation and Thrombosis Mechanisms; Protease and Inhibitor Mechanisms
TL;DR: The therapeutic efficacy of targeted fibrin‐specific nanogel (FSN) design for targeted delivery of tPA to treat thrombotic complications is demonstrated and key translational parameters for tPA‐FSN therapeutics are evaluated, including optimal tPA •FSN dosage in a DIC rodent model and safety of intravenous tPA•FSN therapies. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: December 20, 2021

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2026) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.