Matthew K. Zachek

Works (5)

Updated: July 5th, 2023 15:54

2010 journal article

Carbon Microelectrodes with a Renewable Surface

ANALYTICAL CHEMISTRY, 82(5), 2020–2028.

By: P. Takmakov  n, M. Zachek n, R. Keithley  n, P. Walsh  n, C. Donley  n, G. McCarty n , R. Wightman  n

MeSH headings : Carbon / chemistry; Microelectrodes; Microscopy, Atomic Force; Surface Properties
TL;DR: An electrochemical procedure that constantly renews the surface of a carbon microelectrode using periodic triangle voltage excursions to an extended anodic potential at a scan rate of 400 V s(-1) allows for the regeneration of an electrochemically active surface and restores electrode sensitivity degraded by irreversible adsorption of chemical species. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Characterization of Local pH Changes in Brain Using Fast-Scan Cyclic Voltammetry with Carbon Microelectrodes

ANALYTICAL CHEMISTRY, 82(23), 9892–9900.

By: P. Takmakov  n, M. Zachek n, R. Keithley  n, E. Bucher n, G. McCarty n  & R. Wightman  n

MeSH headings : 3,4-Dihydroxyphenylacetic Acid / chemistry; Animals; Brain / metabolism; Carbon / chemistry; Electrochemical Techniques / methods; Flow Injection Analysis; Hydrogen-Ion Concentration; Male; Microelectrodes; Rats; Rats, Sprague-Dawley
TL;DR: Hypercapnia is demonstrated to be a useful tool to induce robust in vivo pH changes, allowing confirmation of the pH signal observed with FSCV and an extra peak relating to the capacitive nature ofthe pH CV was identified. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Microfabricated FSCV-compatible microelectrode array for real-time monitoring of heterogeneous dopamine release

Analyst [London], 135(7), 1556–1563.

By: M. Zachek, J. Park, P. Takmakov, R. Wightman & G. McCarty 

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Simultaneous Decoupled Detection of Dopamine and Oxygen Using Pyrolyzed Carbon Microarrays and Fast-Scan Cyclic Voltammetry

ANALYTICAL CHEMISTRY, 81(15), 6258–6265.

By: M. Zachek n, P. Takmakov  n, B. Moody n, R. Wightman  n & G. McCarty n 

MeSH headings : Animals; Biosensing Techniques; Brain / metabolism; Carbon / chemistry; Dopamine / analysis; Electrochemistry / instrumentation; Microarray Analysis; Microelectrodes; Oxygen / analysis; Rats; Spectrum Analysis, Raman
TL;DR: The work described in this paper utilizes microfabrication processes to produce devices that enable multiple fast-scan cyclic voltammetry (FSCV) waveforms to be applied to different electrodes on a single substrate, enabling the simultaneous, decoupled detection of dopamine and oxygen. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Electrochemical dopamine detection: Comparing gold and carbon fiber microelectrodes using background subtracted fast scan cyclic voltammetry

JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 614(1-2), 113–120.

By: M. Zachek n, A. Hermans*, R. Wightman * & G. McCarty n 

author keywords: dopamine; carbon fiber microelectrode; Au microelectrode
TL;DR: Dopamine detection on gold microelectrodes was characterized and compared to P-55 carbon fiber micro electrodes of the same geometry, using background subtracted fast scan cyclic voltammetry, and selectivity to dopamine, in comparison to several other neurotransmitters and their derivatives, is described. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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