Megan Leigh Matthews

Works (3)

Updated: October 23rd, 2023 08:15

2023 article

Multiplex CRISPR editing of wood for sustainable fiber production

Sulis, D. B., Jiang, X., Yang, C., Marques, B. M., Matthews, M. L., Miller, Z., … Wang, J. P. (2023, July 13). Science, Vol. 381, pp. 216-+.

By: D. Sulis  n, X. Jiang  n, C. Yang n, B. Marques  n, M. Matthews n, Z. Miller n, K. Lan n , C. Cofre-Vega n ...

Contributors: D. Sulis  n, C. Yang n, B. Liu  n, R. Sederoff n, V. Chiang n, R. Barrangou n , J. Wang n , B. Marques  n ...

MeSH headings : Carbohydrates / analysis; Gene Editing; Lignin / genetics; Wood / genetics; CRISPR-Cas Systems; Populus / genetics; Paper; Sustainable Growth
topics (OpenAlex): Plant Gene Expression Analysis; Biofuel production and bioconversion; Lignin and Wood Chemistry
TL;DR: This work demonstrates that genome editing can be harnessed for breeding more efficient trees, which will provide timely opportunities for sustainable forestry and a more efficient bioeconomy. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 9, 2023

2021 article

Multiscale Modeling of Cross-Regulatory Transcript and Protein Influences

Matthews, M. L., & Williams, C. M. (2021, January 1). Methods in Molecular Biology, Vol. 2328, pp. 115–138.

By: M. Matthews* & C. Williams n 

author keywords: Multiscale modeling; Cross-regulation; Transcript regulation; Protein regulation
MeSH headings : Algorithms; Computational Biology / methods; Gene Expression Profiling / methods; Gene Expression Regulation / genetics; Gene Regulatory Networks / genetics; Metabolomics / methods; Models, Theoretical; Populus / genetics; Populus / metabolism; Proteins / genetics; Proteins / metabolism; Proteomics / methods; Transcriptome / genetics
topics (OpenAlex): RNA Research and Splicing; Bioinformatics and Genomic Networks; RNA and protein synthesis mechanisms
TL;DR: A method is described to model cross-regulatory influences between the transcripts and proteins of a set of genes using abundance data collected from a series of transgenic experiments, using a sparse maximum likelihood algorithm to determine relationships that influence transcript and protein abundance. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: October 4, 2021

2012 article

Region of attraction estimation of biological continuous Boolean models

Matthews, M. L., & Williams, C. M. (2012, October 1). Ieee International Conference on Systems Man and Cybernetics Conference, pp. 1700–1705.

By: M. Matthews n & C. Williams n 

topics (OpenAlex): Gene Regulatory Network Analysis; Microbial Metabolic Engineering and Bioproduction; Gene expression and cancer classification
TL;DR: Assessment of the applicability of a state of the art ROA estimation technique based on interval arithmetic to a subnetwork of the Rb-E2F signaling pathway modeled using continuous Boolean functions shows that this method can successfully be used to provide an estimate of the ROA for dynamic models described using Hillcube continuous Boolean approximations. (via Semantic Scholar)
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15. Life on Land (OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

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