Works (6)
Updated: July 5th, 2023 15:34
2022 journal article
Fentanyl-induced acute and conditioned behaviors in two inbred mouse lines: Potential role for Glyoxalase
PHYSIOLOGY & BEHAVIOR, 243.
author keywords: RNA-sequencing; Opioids; Metabolism; Fentanyl; Conditioned place preference; Acute activity; Conditioned activity
MeSH headings : Animals; COVID-19; Fentanyl / pharmacology; Humans; Mice; Mice, Inbred C57BL; Pandemics; SARS-CoV-2
TL;DR:
Interestingly, few differentially expressed genes were noted using treatment as the main factor, however many genes differed between strains, and it is suggested that future studies assess the ability of Glo1 and related metabolites to modify opioid intake.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: November 29, 2021
2020 review
Mini-review: Epigenetic mechanisms that promote transgenerational actions of endocrine disrupting chemicals: Applications to behavioral neuroendocrinology
[Review of ]. HORMONES AND BEHAVIOR, 119.
author keywords: Chromatin; Transcription factors; CTCF; Transgenerational; Endocrine disrupting chemicals; Methylation; Bisphenol; PCB; Vinclozolin; Phthalates; Estrogen; Androgen
MeSH headings : Animals; Behavior / drug effects; Behavioral Research / methods; Behavioral Research / trends; Cohort Effect; DNA Methylation / drug effects; Endocrine Disruptors / pharmacology; Environmental Exposure / analysis; Environmental Exposure / statistics & numerical data; Epigenesis, Genetic / drug effects; Epigenesis, Genetic / physiology; Female; Humans; Male; Nervous System / drug effects; Nervous System / embryology; Nervous System / growth & development; Neuroendocrinology / methods; Neuroendocrinology / trends; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Prenatal Exposure Delayed Effects / physiopathology; Reproduction / drug effects; Sex Differentiation / drug effects
TL;DR:
The literature on transgenerational actions of endocrine disrupting chemicals (EDCs) on brain and behavior and their underlying epigenetic mechanisms including: DNA methylation, histone modifications, and non-coding RNAs are examined.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: April 6, 2020
2020 journal article
Perinatal Exposure to Methoxychlor Affects Reproductive Function and Sexual Behavior in Mice
FRONTIERS IN ENDOCRINOLOGY, 11.
author keywords: endocrine disruptor; reproduction; hormones; sexual behavior; kisspeptin
MeSH headings : Animals; Endocrine Disruptors / administration & dosage; Estrous Cycle / drug effects; Female; Insecticides / administration & dosage; Kisspeptins / metabolism; Methoxychlor / administration & dosage; Mice; Pregnancy; Prenatal Exposure Delayed Effects / metabolism; Prenatal Exposure Delayed Effects / physiopathology; Preoptic Area / drug effects; Preoptic Area / metabolism; Reproduction / drug effects; Sexual Behavior, Animal / drug effects; Sexual Maturation / drug effects
TL;DR:
Results show that MXC impacts reproductive outcomes, and it is shown that both males and females showed deficits in mate preference tests.
(via Semantic Scholar)
www.frontiersin.org (publisher PDF)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: October 19, 2020
2020 journal article
Sex chromosome complement influences vulnerability to cocaine in mice
HORMONES AND BEHAVIOR, 125.
author keywords: Mice; Cocaine; Self-administration; Sex chromosomes; Locomotor activity; Sex differences; Addiction
MeSH headings : Animals; Behavior, Animal / drug effects; Cocaine / pharmacology; Cocaine-Related Disorders / genetics; Estradiol / physiology; Female; Genetic Predisposition to Disease; Genotype; Gonads / physiology; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Sex Characteristics; Sex Chromosomes / physiology
TL;DR:
The data demonstrate that sex chromosome complement alone and/or interacting with gonadal status can modify cocaine's reinforcing and locomotor-activating effects and inform current studies of sex differences in drug use.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 9, 2020
2020 review
Sexual Differentiation and Substance Use: A Mini-Review
[Review of ]. ENDOCRINOLOGY, 161(9).
author keywords: cocaine; sexual differentiation; mice; sex chromosomes; dopamine; estrogen
MeSH headings : Aging / drug effects; Aging / physiology; Animals; Brain / drug effects; Brain / physiology; Gonadal Steroid Hormones / pharmacology; Humans; Reward; Risk Factors; Sex Characteristics; Sex Differentiation / physiology; Sex Factors; Substance-Related Disorders / epidemiology; Substance-Related Disorders / etiology
TL;DR:
It is proposed that sex chromosome complement also plays a role in determining sex-specific drug-taking behavior and the four core genotypes mouse model is proposed as an effective tool for answering these questions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: September 28, 2020
2018 journal article
Kisspeptin system in ovariectomized mice: Estradiol and progesterone regulation
BRAIN RESEARCH, 1688, 8–14.
author keywords: Kisspeptin; Estrogen; Progesterone; Periventricular region; Arcuate nucleus; Paraventricular nucleus
MeSH headings : Animals; Arcuate Nucleus of Hypothalamus / drug effects; Arcuate Nucleus of Hypothalamus / metabolism; Estradiol / administration & dosage; Estradiol / metabolism; Estrous Cycle; Female; Kisspeptins / metabolism; Mice; Neurons / metabolism; Ovariectomy; Paraventricular Hypothalamic Nucleus / drug effects; Paraventricular Hypothalamic Nucleus / metabolism; Progesterone / administration & dosage; Progesterone / metabolism
TL;DR:
Investigating the role played by progesterone (P) or estradiol (E2), alone or together, on the kisspeptin system and how this affects innervation of the PVN suggests that these fibers arrive from both RP3V and ARC nuclei.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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