Mindy Miller-Kittrell

Works (3)

Updated: July 5th, 2023 15:46

2016 journal article

A little cooperation helps murine cytomegalovirus (MCMV) go a long way: MCMV co-infection rescues a chemokine salivary gland defect

Journal of General Virology, 97, 2957–2972.

By: P. Dogra, M. Miller-Kittrell, E. Pitt, J. Jackson, T. Masi, C. Copeland, S. Wu, W. Miller, T. Sparer

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Modulation of innate immune signaling by the secreted form of the West Nile virus NS1 glycoprotein

VIROLOGY, 458, 172–182.

By: K. Crook n, M. Miller-Kittrell n, C. Morrison n & F. Scholle n

author keywords: West Nile virus; Flaviviridae; Nonstructural protein; Toll like receptor; Innate immunity
MeSH headings : Animals; HeLa Cells; Humans; Immunity, Innate; Luciferases / metabolism; Macrophages / immunology; Macrophages / metabolism; Mice; Mice, Inbred C57BL; Myeloid Cells / immunology; Myeloid Cells / metabolism; Poly I-C / pharmacology; Signal Transduction / immunology; Specific Pathogen-Free Organisms; Toll-Like Receptor 3 / antagonists & inhibitors; Viral Nonstructural Proteins / immunology; Viral Nonstructural Proteins / physiology; West Nile virus / immunology; West Nile virus / metabolism
TL;DR: Investigating whether the secreted form of NS1 inhibits innate immune signaling pathways in uninfected cells reduces TLR3 signaling and WNV replicon particle-mediated cytokine transcription in popliteal lymph nodes found the protein associated predominantly with macrophages and dendritic cells in the draining lymph node. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Intrinsic adjuvanting of a novel single-cycle flavivirus vaccine in the absence of type I interferon receptor signaling

VACCINE, 30(8), 1465–1475.

By: E. Winkelmann, D. Widman*, J. Xia*, T. Ishikawa, M. Miller-Kittrell n, M. Nelson *, N. Bourne*, F. Scholle n, P. Mason*, G. Milligan *

author keywords: West Nile virus; Single-cycle virus; CD8(+) T cell; Type I IFN
MeSH headings : Adjuvants, Immunologic / pharmacology; Animals; Antibodies, Viral / blood; CD4-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / immunology; Immunoglobulin G / blood; Lymph Nodes / immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Interferon alpha-beta / deficiency; Receptor, Interferon alpha-beta / immunology; Signal Transduction; West Nile Fever / immunology; West Nile Fever / prevention & control; West Nile Virus Vaccines / immunology
TL;DR: Results indicate that although type I IFN is not essential for the intrinsic adjuvanting of RepliVAX WN, it plays a role in shaping the cytokine secretion profiles of CD8(+) effector T cells elicited by this SCFV. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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