Mindy Miller-Kittrell

Works (3)

Updated: July 5th, 2023 15:46

2016 journal article

A little cooperation helps murine cytomegalovirus (MCMV) go a long way: MCMV co-infection rescues a chemokine salivary gland defect

Journal of General Virology, 97, 2957–2972.

By: P. Dogra, M. Miller-Kittrell, E. Pitt, J. Jackson, T. Masi, C. Copeland, S. Wu, W. Miller, T. Sparer

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Modulation of innate immune signaling by the secreted form of the West Nile virus NS1 glycoprotein

VIROLOGY, 458, 172–182.

By: K. Crook n, M. Miller-Kittrell n, C. Morrison n & F. Scholle n 

author keywords: West Nile virus; Flaviviridae; Nonstructural protein; Toll like receptor; Innate immunity
MeSH headings : Animals; HeLa Cells; Humans; Immunity, Innate; Luciferases / metabolism; Macrophages / immunology; Macrophages / metabolism; Mice; Mice, Inbred C57BL; Myeloid Cells / immunology; Myeloid Cells / metabolism; Poly I-C / pharmacology; Signal Transduction / immunology; Specific Pathogen-Free Organisms; Toll-Like Receptor 3 / antagonists & inhibitors; Viral Nonstructural Proteins / immunology; Viral Nonstructural Proteins / physiology; West Nile virus / immunology; West Nile virus / metabolism
topics (OpenAlex): Mosquito-borne diseases and control; Viral Infections and Vectors; Malaria Research and Control
TL;DR: Investigating whether the secreted form of NS1 inhibits innate immune signaling pathways in uninfected cells reduces TLR3 signaling and WNV replicon particle-mediated cytokine transcription in popliteal lymph nodes found the protein associated predominantly with macrophages and dendritic cells in the draining lymph node. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Intrinsic adjuvanting of a novel single-cycle flavivirus vaccine in the absence of type I interferon receptor signaling

VACCINE, 30(8), 1465–1475.

By: E. Winkelmann, D. Widman *, J. Xia*, T. Ishikawa, M. Miller-Kittrell n, M. Nelson *, N. Bourne*, F. Scholle n , P. Mason*, G. Milligan *

author keywords: West Nile virus; Single-cycle virus; CD8(+) T cell; Type I IFN
MeSH headings : Adjuvants, Immunologic / pharmacology; Animals; Antibodies, Viral / blood; CD4-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / immunology; Immunoglobulin G / blood; Lymph Nodes / immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Interferon alpha-beta / deficiency; Receptor, Interferon alpha-beta / immunology; Signal Transduction; West Nile Fever / immunology; West Nile Fever / prevention & control; West Nile Virus Vaccines / immunology
topics (OpenAlex): Mosquito-borne diseases and control; Viral Infections and Vectors; interferon and immune responses
TL;DR: Results indicate that although type I IFN is not essential for the intrinsic adjuvanting of RepliVAX WN, it plays a role in shaping the cytokine secretion profiles of CD8(+) effector T cells elicited by this SCFV. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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