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Works (33)
Updated: August 16th, 2024 13:37
2023 article
Draft Genome Sequences of Escherichia coli and Enterococcus faecalis Coisolated from Polymicrobial Extraintestinal Infections of Chickens and Turkeys
Walker, G. K., Harden, L., Suyemoto, M. M., Thakur, S., Jacob, M., & Borst, L. B. (2023, February 21). MICROBIOLOGY RESOURCE ANNOUNCEMENTS, Vol. 2.
TL;DR:
It is reported that draft genome sequences of 18 APEC and 18 E. faecalis strains coisolated from lesions of diseased poultry with colisepticemia are reported.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 20, 2023
2023 article
Draft genome sequences of 12 Escherichia coli co-isolated with Enterococcus spp. from dogs with polybacterial bacteriuria at a veterinary hospital
Walker, G. K., Harden, L., Suyemoto, M. M., Thakur, S., Jacob, M., & Borst, L. B. (2023, August 8). MICROBIOLOGY RESOURCE ANNOUNCEMENTS, Vol. 8.
author keywords: E; coli; UPEC; canine urinary tract infection; polymicrobial infections
TL;DR:
The draft genome sequences of 12 UPEC co-isolated with Enterococcus spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 21, 2023
2023 article
Nonredundant Dimethyl Sulfoxide Reductases Influence Salmonella enterica Serotype Typhimurium Anaerobic Growth and Virulence
Cruz, E., Haeberle, A. L., Westerman, T. L., Durham, M. E., Suyemoto, M. M., Knodler, L. A., & Elfenbein, J. R. (2023, February 1). INFECTION AND IMMUNITY.
author keywords: DMSO; Salmonella; anaerobic metabolism; bovine ileal loop model; dimethyl sulfoxide; murine infection; type 3 secretion system
MeSH headings : Animals; Virulence; Anaerobiosis; Type III Secretion Systems / metabolism; Dimethyl Sulfoxide / pharmacology; Dimethyl Sulfoxide / metabolism; Serogroup; Oxidoreductases / metabolism; Salmonella typhimurium; Mammals
TL;DR:
It is demonstrated that an S. enterica serotype Typhimurium mutant with loss of function in all three putative DMSO reductases (ΔdmsA3) poorly colonizes the mammalian intestine when the microbiota is intact and when inflammation is absent, and suggest D MSO is a physiologically relevant electron acceptor that supports S. entersica fitness in the gut.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: March 13, 2023
2021 journal article
Genomic Characterization of a Nalidixic Acid-Resistant Salmonella Enteritidis Strain Causing Persistent Infections in Broiler Chickens
FRONTIERS IN VETERINARY SCIENCE, 8.
author keywords: Salmonella Enteritidis; poultry; genomics; antimicrobial resistance; broilers
TL;DR:
P phenotypic and genomic features of a virulent SE strain from persistently infected broiler flocks are reported and a workflow for SE characterization from isolate collection to genome assembly and sequence analysis is presented.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 27, 2021
2020 journal article
Research Note: Repetitive element–based polymerase chain reaction genotyping improves efficiency of Salmonella surveillance in a model broiler production system
Poultry Science, 99(5), 2684–2689.
author keywords: Salmonella; antimicrobial resistance; broiler; microbiology; genetic characterization
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Chickens; DNA Fingerprinting / veterinary; Drug Resistance, Bacterial / genetics; Epidemiological Monitoring / veterinary; Genotyping Techniques / veterinary; Polymerase Chain Reaction / veterinary; Poultry Diseases / epidemiology; Poultry Diseases / microbiology; Prevalence; Salmonella / genetics; Salmonella / isolation & purification; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / microbiology; Serotyping / veterinary
TL;DR:
Genetic relatedness and antimicrobial susceptibility profiles of Salmonella isolated from poultry and their environment were determined and demonstrated that serovar Altona and Senftenberg were harbored by poultry, the latter appeared to persist in broiler flocks, and both serotypes shared similar patterns of antimacterial susceptibility in an integrated research operation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: June 1, 2020
2020 journal article
The role ofEnterococcus faecalisduring co-infection with avian pathogenicEscherichia coliin avian colibacillosis
AVIAN PATHOLOGY, 49(6), 589–599.
author keywords: Colibacillosis; Enterococcus; E; coli; co-infection; antimicrobial resistance; broiler; turkey
MeSH headings : Animals; Chick Embryo; Chickens / microbiology; Coinfection / veterinary; Enterococcus faecalis / physiology; Escherichia coli / physiology; Escherichia coli Infections / microbiology; Escherichia coli Infections / pathology; Escherichia coli Infections / veterinary; Female; Gram-Positive Bacterial Infections / microbiology; Gram-Positive Bacterial Infections / pathology; Gram-Positive Bacterial Infections / veterinary; Phenotype; Poultry Diseases / epidemiology; Poultry Diseases / microbiology; Poultry Diseases / pathology; Virulence
TL;DR:
Enterococcus is frequently co-isolated with avian pathogenic E. coli from poultry with colibacillosis, and Enterococcus faecalis (EF) enhances survival of APEC in iron restricted conditions and increases APEC virulence in broiler embryos.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 28, 2020
2019 journal article
Temporal characterization of wooden breast myopathy ("woody breast") severity and correlation with growth rate and lymphocytic phlebitis in three commercial broiler strains and a random-bred broiler strain
AVIAN PATHOLOGY, 48(4), 319–328.
author keywords: Athens Canadian Random Bred; broiler chickens; growth rate; incubation temperature; lymphocytic phlebitis; pectoralis major muscle; wooden breast myopathy
MeSH headings : Animals; Body Weight; Chickens / growth & development; Female; Lymphatic Vessels / pathology; Lymphatic Vessels / physiopathology; Male; Meat / economics; Meat / standards; Muscular Diseases / pathology; Muscular Diseases / physiopathology; Muscular Diseases / veterinary; Pectoralis Muscles / pathology; Pectoralis Muscles / physiopathology; Phlebitis / etiology; Phlebitis / veterinary; Poultry Diseases / pathology; Poultry Diseases / physiopathology; Random Allocation; Sex Factors; Temperature
TL;DR:
The positive correlation between WBM severity and lymphocytic phlebitis indicates vascular injury is likely an important factor in the pathogenesis of Wooden breast myopathy.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 17, 2019
2019 journal article
Wooden Breast in Commercial Broilers Associated with Mortality, Dorsal Recumbency, and Pulmonary Disease
AVIAN DISEASES, 63(3), 514–519.
author keywords: broiler chicken; lungs; mortality; muscular dystrophy; myopathy; Pectoralis major muscle; pulmonary disease; wooden breast
MeSH headings : Animals; Chickens; Female; Lung Diseases / epidemiology; Lung Diseases / etiology; Male; Meat / analysis; Muscular Diseases / mortality; Muscular Diseases / pathology; Muscular Diseases / veterinary; Pectoralis Muscles / pathology; Poultry Diseases / mortality; Poultry Diseases / pathology; Prevalence
TL;DR:
Findings indicate that wooden breast is likely greater than just a problem with meat quality and should be considered an animal well-being issue.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 20, 2020
2018 journal article
Vaccination of breeder hens with a polyvalent killed vaccine for pathogenic Enterococcus cecorum does not protect offspring from enterococcal spondylitis
AVIAN PATHOLOGY, 48(1), 17–24.
author keywords: Enterococcus cecorum; kinky-back; vaccine; broiler health; lameness; enterococcal spondylitis
MeSH headings : Animals; Chickens / immunology; Chickens / microbiology; Disease Outbreaks / veterinary; Enterococcus / immunology; Enterococcus / pathogenicity; Female; Genotype; Gram-Positive Bacterial Infections / microbiology; Gram-Positive Bacterial Infections / prevention & control; Poultry Diseases / microbiology; Poultry Diseases / prevention & control; Spondylitis / microbiology; Spondylitis / prevention & control; Vaccination / veterinary; Vaccines, Inactivated / immunology; Virulence
TL;DR:
Data suggest that pathogenic strains of E. cecorum possess virulence mechanisms that confound antibody-mediated opsinophagocytosis, complicating vaccine development for this pathogen of broilers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 7, 2019
2017 journal article
Prevalence and severity of osteochondrosis of the free thoracic vertebra in three modern broiler strains and the Athens Canadian Random Bred control broiler
Avian Pathology, 47(2), 152–160.
author keywords: Osteochondrosis; enterococcal spondylitis; Enterococcus cecorum; genetics; sex-associated
MeSH headings : Animals; Chickens; Female; Genetic Predisposition to Disease; Male; Osteochondrosis / epidemiology; Osteochondrosis / genetics; Osteochondrosis / pathology; Osteochondrosis / veterinary; Poultry Diseases / epidemiology; Poultry Diseases / genetics; Poultry Diseases / pathology; Prevalence; Risk Factors
TL;DR:
Findings indicate that OCD of the FTV is common in broiler chickens with similar prevalence observed in broilers with modern genetics and the ACRB broilers which represent 1950s broiler genetics.
(via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2016 journal article
Culture methods impact recovery of antibiotic-resistant Enterococci including Enterococcus cecorum from pre- and postharvest chicken
LETTERS IN APPLIED MICROBIOLOGY, 64(3), 210–216.
author keywords: food safety; lactic acid bacteria; postharvest; resistance; veterinary
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacteriological Techniques / methods; Cecum / microbiology; Chickens; Drug Resistance, Bacterial; Enterococcus / drug effects; Enterococcus / genetics; Enterococcus / growth & development; Enterococcus / isolation & purification; Gram-Positive Bacterial Infections / microbiology; Meat / microbiology; Microbial Sensitivity Tests; Poultry Diseases / microbiology
TL;DR:
Findings confirm that current methodologies may not accurately identify the amount and range of antimicrobial resistance of enterococci from chicken sources and significantly affected recovery ofEnterococcal species other than EC.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Pathogenesis of Enterococcal Spondylitis Caused by Enterococcus cecorum in Broiler Chickens
Veterinary Pathology, 54(1), 61–73.
author keywords: Enterococcus cecorum; enterococcal spondylitis; osteochondrosis dissecans; osteochondritis dissecans; kinky back; broiler; chickens; neurologic disease; vertebral osteoarthritis
MeSH headings : Animals; Chickens / microbiology; Enterococcus / genetics; Gram-Positive Bacterial Infections / complications; Gram-Positive Bacterial Infections / microbiology; Gram-Positive Bacterial Infections / veterinary; Intestines / microbiology; Paralysis / etiology; Paralysis / microbiology; Paralysis / veterinary; Phylogeny; Poultry Diseases / etiology; Poultry Diseases / microbiology; Poultry Diseases / mortality; Spleen / microbiology; Spondylitis / microbiology; Spondylitis / veterinary; Thoracic Vertebrae / microbiology
TL;DR:
It is suggested that intestinal colonization, bacteremia, and OCD of the FTV in early life are crucial to the pathogenesis of ES.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2015 journal article
Comparative Genomic Analysis Identifies Divergent Genomic Features of Pathogenic Enterococcus cecorum Including a Type IC CRISPR-Cas System, a Capsule Locus, an epa-Like Locus, and Putative Host Tissue Binding Proteins
PLOS ONE, 10(4).
MeSH headings : Animals; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; CRISPR-Cas Systems / genetics; Chickens; Comparative Genomic Hybridization; Enterococcus / classification; Enterococcus / genetics; Enterococcus / isolation & purification; Evolution, Molecular; Genetic Loci; Genome, Bacterial; Genomics; Genotype; Phylogeny; Poultry Diseases / epidemiology; Poultry Diseases / microbiology; Virulence / genetics
TL;DR:
Specific genomic regions, coding sequences, and predicted proteins which may be related to the divergent evolution and increased virulence of emerging pathogenic strains of EC are identified and potential mediators of virulence identified.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
A Chicken Embryo Lethality Assay for Pathogenic Enterococcus cecorum
AVIAN DISEASES, 58(2), 244–248.
author keywords: broiler; chicken; Enterococcus cecorum; enterococcal spondylitis; chicken embryo lethality assay
MeSH headings : Animals; Chick Embryo; Chickens; Electrophoresis, Gel, Pulsed-Field / veterinary; Enterococcus / genetics; Enterococcus / isolation & purification; Enterococcus / pathogenicity; Enterococcus / physiology; Gram-Positive Bacterial Infections / diagnosis; Gram-Positive Bacterial Infections / epidemiology; Gram-Positive Bacterial Infections / microbiology; Gram-Positive Bacterial Infections / veterinary; Phylogeny; Poultry Diseases / diagnosis; Poultry Diseases / epidemiology; Poultry Diseases / microbiology; United States; Virulence
TL;DR:
This embryo lethality assay provides a useful tool for understanding the genetic basis of E. cecorum virulence and causes outbreaks of arthritis and osteomyelitis in chickens worldwide.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2013 journal article
Extrauterine Listeriosis in the gravid mouse influences embryonic growth and development
PLoS One, 8(8).
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
Mortality in Kittens Is Associated with a Shift in Ileum Mucosa-Associated Enterococci from Enterococcus hirae to Biofilm-Forming Enterococcus faecalis and Adherent Escherichia coli
JOURNAL OF CLINICAL MICROBIOLOGY, 51(11), 3567–3578.
MeSH headings : Animals; Animals, Newborn; Biofilms / growth & development; Biota; Cat Diseases / microbiology; Cat Diseases / mortality; Cats; Enteritis / microbiology; Enteritis / mortality; Enteritis / veterinary; Enterococcus / isolation & purification; Enterococcus / physiology; Escherichia coli / isolation & purification; Escherichia coli / physiology; Ileum / microbiology; Intestinal Mucosa / microbiology
TL;DR:
A significant difference is identified in the species of enterococci cultured from the ileum mucosa of kittens with terminal illness compared to the species cultured from healthy kittens, which is identified as more common and extensive in healthy kittens than in sick kittens.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
An Outbreak and Source Investigation of Enterococcal Spondylitis in Broilers Caused by Enterococcus cecorum
AVIAN DISEASES, 56(4), 768–773.
author keywords: broiler; chicken; Enterococcus cecorum; enterococcal spondylitis
MeSH headings : Animals; Bacterial Typing Techniques / veterinary; Cecum / microbiology; Chickens; Cloaca / microbiology; Disease Outbreaks / veterinary; Electrophoresis, Gel, Pulsed-Field / veterinary; Enterococcus / isolation & purification; Enterococcus / physiology; Fatal Outcome; Gram-Positive Bacterial Infections / diagnosis; Gram-Positive Bacterial Infections / epidemiology; Gram-Positive Bacterial Infections / microbiology; Gram-Positive Bacterial Infections / veterinary; North Carolina / epidemiology; Phenotype; Poultry Diseases / diagnosis; Poultry Diseases / epidemiology; Poultry Diseases / microbiology; Spondylitis / diagnosis; Spondylitis / epidemiology; Spondylitis / microbiology; Spondylitis / veterinary
TL;DR:
Enterococcus cecorum was isolated from spondylitis lesions in broilers from two flocks in North Carolina that were experiencing increased mortality and revealed paresis and paralysis, clinical signs characteristic of enterococcal spONDylitis (ES).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Molecular epidemiology of Enterococcus cecorum isolates recovered from enterococcal spondylitis outbreaks in the southeastern United States
AVIAN PATHOLOGY, 41(5), 479–485.
MeSH headings : Animals; Case-Control Studies; Cecum / microbiology; Cecum / pathology; Chickens; Cluster Analysis; Disease Outbreaks / veterinary; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field / veterinary; Enterococcus / genetics; Enterococcus / isolation & purification; Enterococcus / pathogenicity; Genetic Variation; Genotype; Gram-Positive Bacterial Infections / epidemiology; Gram-Positive Bacterial Infections / microbiology; Gram-Positive Bacterial Infections / veterinary; Male; Mannitol / metabolism; Molecular Epidemiology; Phenotype; Poultry Diseases / epidemiology; Poultry Diseases / microbiology; Southeastern United States / epidemiology; Spondylitis / epidemiology; Spondylitis / microbiology; Spondylitis / veterinary
TL;DR:
Findings indicate that the increase in E. cecorum-associated disease in the southeast United States is due to the emergence of new clones with increased pathogenicity and multidrug resistance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
In Vitro Properties of a Listeria monocytogenes Bacteriophage-Resistant Mutant Predict Its Efficacy as a Live Oral Vaccine Strain
INFECTION AND IMMUNITY, 79(12), 5001–5009.
MeSH headings : Administration, Oral; Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bacterial Vaccines / administration & dosage; Bacterial Vaccines / immunology; Bacterial Vaccines / standards; Bacteriophages / physiology; Cells, Cultured; Enterocytes / microbiology; Female; Listeria monocytogenes / genetics; Listeria monocytogenes / virology; Listeriosis / microbiology; Listeriosis / prevention & control; Mice; Mice, Inbred BALB C; Mutagenesis, Insertional; Mutation; Time Factors; Vaccines, Attenuated / administration & dosage; Vaccines, Attenuated / standards
TL;DR:
The results indicate that oral administration of a profoundly attenuated listeria monocytogenes glcV mutant can safely elicit solid protective immunity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Zebrafish (Danio rerio) as a Screen for Attenuation of Lancefield Group C Streptococci and a Model for Streptococcal Pathogenesis
VETERINARY PATHOLOGY, 50(3), 457–467.
author keywords: animal model; Danio rerio; strangles; streptococcus; zebrafish
MeSH headings : Acute-Phase Proteins / metabolism; Animals; Anti-Infective Agents / metabolism; Blood Coagulation Factors / metabolism; Comparative Genomic Hybridization / veterinary; Disease Models, Animal; Female; Fish Diseases / immunology; Fish Diseases / microbiology; Gene Expression Regulation, Bacterial; Injections, Intramuscular; Kidney / pathology; Male; Muscles / pathology; Mutation; Spleen / pathology; Streptococcal Infections / immunology; Streptococcal Infections / microbiology; Streptococcus / genetics; Streptococcus / immunology; Streptococcus / pathogenicity; Streptococcus equi / genetics; Streptococcus equi / immunology; Streptococcus equi / pathogenicity; Virulence; Virulence Factors / genetics; Zebrafish / genetics; Zebrafish / immunology; Zebrafish / microbiology
TL;DR:
Collectively, these collective findings underscore the value of the zebrafish as a model of streptococcal pathogenesis as well as the need for further research on this topic.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2010 journal article
Factors Associated with the Acquisition and Severity of Gestational Listeriosis
PLOS ONE, 5(9).
MeSH headings : Animals; Disease Models, Animal; Female; Humans; Listeria / physiology; Listeriosis / embryology; Listeriosis / microbiology; Listeriosis / pathology; Liver / microbiology; Liver / pathology; Mice; Pregnancy; Pregnancy Complications, Infectious / microbiology; Pregnancy Complications, Infectious / pathology; Severity of Illness Index; Spleen / microbiology; Spleen / pathology
TL;DR:
It was determined in mice that increased susceptibility to lethal infection following oral inoculation begins surprisingly early in pregnancy and extends through embryonic development, and the window of listeriosis susceptibility afforded by pregnancy may be open longer than previously appreciated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2008 journal article
A Listeria monocytogenes mutant defective in bacteriophage attachment is attenuated in orally inoculated mice and impaired in enterocyte intracellular growth
INFECTION AND IMMUNITY, 76(9), 4046–4054.
MeSH headings : Animals; Bacterial Adhesion; Bacteriophages / physiology; DNA Transposable Elements; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Enterocytes / microbiology; Female; Genetic Complementation Test; Glycosyltransferases / genetics; Listeria monocytogenes / pathogenicity; Listeria monocytogenes / virology; Listeriosis / microbiology; Liver / microbiology; Mice; Mice, Inbred A; Molecular Sequence Data; Mutagenesis, Insertional; Receptors, Virus / genetics; Sequence Analysis, DNA; Spleen / microbiology; Survival Analysis; Viral Plaque Assay; Virulence; Virulence Factors / genetics; Virus Attachment
TL;DR:
Interestingly, the glcV lesion, while preventing phage attachment, did not alter the mutant's ability to bind to cultured mouse enterocyte monolayers, rather, the mutation appeared to alter a subsequent step in intracellular replication measured by a reduction in plaque-forming efficiency and plaque size.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Formate acts as a diffusible signal to induce Salmonella invasion
JOURNAL OF BACTERIOLOGY, 190(12), 4233–4241.
MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / physiology; Cell Line; Culture Media, Conditioned / pharmacology; Epithelial Cells / microbiology; Female; Formates / metabolism; Formates / pharmacology; Gene Expression Regulation, Bacterial / drug effects; Genomic Islands / genetics; Mice; Mice, Inbred C57BL; Models, Biological; Protons; Pyruvic Acid / pharmacology; Reverse Transcriptase Polymerase Chain Reaction; Salmonella typhimurium / drug effects; Salmonella typhimurium / genetics; Salmonella typhimurium / pathogenicity; Signal Transduction / drug effects; Signal Transduction / genetics; Signal Transduction / physiology
TL;DR:
It was found that formate affected the major regulators of SPI1, hilA and hilD, but that the primary routes of formate metabolism played no role in its activity as a signal.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA
Nucleic Acids Research, 35(4), 1222–1229.
MeSH headings : Aptamers, Nucleotide / chemistry; Boron Compounds / chemical synthesis; Boron Compounds / chemistry; Boron Compounds / metabolism; DNA / biosynthesis; DNA / chemistry; DNA Primers; DNA-Directed DNA Polymerase / metabolism; Polymerase Chain Reaction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Templates, Genetic; Thymine Nucleotides / chemical synthesis; Thymine Nucleotides / chemistry; Thymine Nucleotides / metabolism
TL;DR:
It is demonstrated that DNA polymerase can effectively recognize the B-TTP as the template for DNA polymerization, that allows PCR amplification of boronic acid-labeled DNA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2007 journal article
Genome-wide screen of Salmonella genes expressed during infection in pigs, using in vivo expression technology
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 73(23), 7522–7530.
MeSH headings : Animals; Fimbriae, Bacterial / genetics; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genes, Bacterial / genetics; Genome, Bacterial; Iron-Sulfur Proteins / genetics; Lipopolysaccharides / metabolism; Promoter Regions, Genetic / genetics; Recombinases / genetics; Salmonella / genetics; Salmonella / pathogenicity; Salmonella Infections / microbiology; Swine / microbiology; Virulence / genetics; Vitamin B 12 / genetics
TL;DR:
A recombinase-based promoter-trapping strategy is devised to identify genes with elevated expression during pig infection with Salmonella enterica serovar Typhimurium, suggesting possible signals for expression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Identification of CsrC and characterization of its role in epithelial cell invasion in Salmonella enterica serovar Typhimurium
INFECTION AND IMMUNITY, 74(1), 331–339.
MeSH headings : Bacterial Proteins / genetics; Base Sequence; Cell Line, Tumor; Epithelial Cells / microbiology; Genes, Regulator; Humans; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Bacterial / chemistry; RNA, Bacterial / genetics; RNA, Bacterial / physiology; RNA, Long Noncoding; RNA, Untranslated / genetics; RNA, Untranslated / physiology; Salmonella typhimurium / genetics; Salmonella typhimurium / pathogenicity; Trans-Activators / genetics
TL;DR:
It is shown that CsrC, like CsrB, is controlled by the BarA/SirA two-component regulator but that a csrB csrC mutant exhibits a loss of invasion equivalent to that of a barA or sirA mutant, indicating that much of the effect of BarA /SirA on invasion functions through its control of CSRB and CSRC.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Intestinal short-chain fatty acids alter Salmonella typhimurium invasion gene expression and virulence through BarA/SirA
MOLECULAR MICROBIOLOGY, 46(5), 1451–1464.
MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Cell Line; Escherichia coli Proteins; Fatty Acids / pharmacology; Female; Gene Expression Regulation, Bacterial; Humans; Intestines / chemistry; Membrane Proteins / genetics; Membrane Proteins / metabolism; Mice; Mice, Inbred BALB C; Phosphotransferases; Salmonella Infections, Animal / microbiology; Salmonella typhimurium / genetics; Salmonella typhimurium / pathogenicity; Sepsis / microbiology; Trans-Activators / genetics; Trans-Activators / metabolism; Virulence / genetics
TL;DR:
The results suggest that the concentration and composition of SCFAs in the distal ileum provide a signal for productive infection by Salmonella, whereas those of the large intestine inhibit invasion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
In Vitro and In Vivo Assessment of Salmonella enterica Serovar Typhimurium DT104 Virulence
Infection and Immunity, 69(7), 4673–4677.
MeSH headings : Animals; Disease Models, Animal; Humans; Hydrogen Peroxide / pharmacology; Macrophages, Peritoneal / microbiology; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Nitrates / pharmacology; Salmonella Infections / microbiology; Salmonella typhimurium / drug effects; Salmonella typhimurium / growth & development; Salmonella typhimurium / isolation & purification; Salmonella typhimurium / pathogenicity; Tumor Cells, Cultured; Virulence
TL;DR:
In vitro and in vivo virulence-associated phenotypes of several clinical isolates of S. enterica serovar Typhimurium DT104 isolates failed to demonstrate that these strains are more virulent than S. entersicaserovar Typhoon ATCC 14028s.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2000 journal article
Characterization of two novel regulatory genes affecting Salmonella invasion gene expression
MOLECULAR MICROBIOLOGY, 35(3), 635–646.
MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; Carcinoma, Hepatocellular / microbiology; Chromosome Deletion; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genes, Regulator; Humans; Membrane Proteins / genetics; Membrane Proteins / metabolism; Molecular Sequence Data; Mutation; Phosphotransferases; RNA, Bacterial / metabolism; RNA, Long Noncoding; RNA, Untranslated; RNA-Binding Proteins / genetics; RNA-Binding Proteins / metabolism; Repressor Proteins; Salmonella typhimurium / genetics; Salmonella typhimurium / pathogenicity; Suppression, Genetic; Trans-Activators / genetics; Trans-Activators / metabolism; Tumor Cells, Cultured
TL;DR:
The results identify a protein that is likely to play a key role in the environmental control of Salmonella invasion gene expression, and they suggest that transcriptional control of invasion genes could be subject to refinement at the level of message turnover.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Regulation of Salmonella enterica serovar typhimurium invasion genes by csrA
INFECTION AND IMMUNITY, 68(12), 6790–6797.
MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / physiology; Base Sequence; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Humans; Molecular Sequence Data; RNA-Binding Proteins / physiology; Repressor Proteins; Salmonella typhimurium / genetics; Salmonella typhimurium / pathogenicity; Trans-Activators / genetics
TL;DR:
It is reported here that epithelial cell invasion requires the serovar Typhimurium homologue of Escherichia coli csrA, which encodes a regulator that alters the stability of specific mRNA targets, and it is found that CsrA affected hilA, a regulator of the other three genes the authors tested, probably by controlling one or more genetic elements that regulate hILA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1999 journal article
A recombinase-based selection of differentially expressed bacterial genes
GENE, 240(1), 99–106.
author keywords: Cre; invasion; loxP; sacB; Salmonella
MeSH headings : DNA, Bacterial / genetics; DNA, Recombinant; Gene Expression Regulation, Bacterial; Genes, Bacterial / genetics; Genes, Reporter / genetics; Humans; Integrases / genetics; Lac Operon / genetics; Plasmids / genetics; Recombinant Fusion Proteins / genetics; Recombination, Genetic; Salmonella typhimurium / genetics; Transformation, Genetic; Tumor Cells, Cultured; Viral Proteins
TL;DR:
This system is used to identify S. typhimurium genes that are specifically expressed when bacteria interact with cultured epithelial cells and identified a novel DNA fragment, not found in E. coli, which might represent part of a new pathogenicity island.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1997 journal article
Nucleic acid amplification for rapid detection of Rhodococcus equi in equine blood and tracheal wash fluids
American Journal of Veterinary Research, 58(11), 1232–1237.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Stability and bioactivity of tetracycline hydrochloride water medication in a swine production unit
Mason, S. E., Suyemoto, M., Baynes, R., & Almond, G. Journal of Swine Health and Production, 19(2), 107–111.
Source: NC State University Libraries
Added: August 6, 2018
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